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Protective effect of early enteral feeding on postburn impairment of liver function and its mechanism in rats

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World Journal of Gastroenterology 2000年第1期6卷 79-83页

作者： zhu l Yang ZC li A Cheng DC Institute of Burn Research Southwest HospitalThird Military Medical UniversityChongqing 400038China Critical Care Department Peking Union Medical College Hospital(PUMCH)Chinese Academy of Medical science(CAMS)Beijing 100730China

AIM To study the protective effect of earlyenteral feeding(EEF)on the postburnimpairment of liver function and its *** Wistar rats with 30% of total bodysurface area(TBSA)full-thickness burn *** effects of EEF on the postburnchanges of gastric intramucosal pH,endotoxinlevels in portal vein,water contents of hepatictissue,blood concentrations of tumor necrosisfactor(TNF-α),plasma activities of alanineaminotransferase(AlT)and asparateaminotransferase(AST),as well as the bloodcontents of total(TB)and direct bilirubin(DB),total protein(TP)and albumin(AlB)wereserially determined within 48h *** EEF could significantly improvegastric mucosal acidosis,reduce portal veinendotoxin level and water content of hepatictissue,as well as plasma concentrations of TNF-α at all timepoints after severe burns(P<0.01);postburn elevation of the plasma activities ofAlT,AST and the contents of TB,DB wereeffectively prevented,whereas the plasmaconcentrations of TP and AlB were markedlyincreased 24 h and 48 h posturn in EEF groupcompared with that of the burn without EEFgroup(P<0.01).CONClUSION EEF has significant beneficialeffects on the improvement of hepatic function in rats after severe burn,and is probably relatedwith an increase in splanchnic blood flow,reduction of the absorption of gut-originendotoxin and the consequent release ofinflammatory mediators.

关键词： Subject headings early enteral feeding liver postburn impairments

Reduced gastric acid production in burn shock period and its significance in the prevention and treatment of acute gastric mucosal lesions

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World Journal of Gastroenterology 2000年第1期6卷 84-88页

AIM To investigate the changes of gastric acidproduction and its mechanism in shock period ofsevere burn in *** A rat model with 30% TBSA full-thickness burn injury was employed and thegastric acid production,together with gastricmucosal blood flow(GMBF)and energy charge(EC)were measured serially within *** The gastric acid production in theacute shock period was markedly inhibited aftersevere burn *** the 3rd h postburn,thegastric juice volume,total acidity and acidoutput were already significantly decreased(P<0.01),and reached the lowest point,0.63ml/l±0.20ml/l,10.81mmol/l±2.58mmol/l and 2.23mmol/h±0.73mmol/hrespectively,at the 12th h *** to some degree 24 h after thermalinjury,the variables above were stillstatistically lower,compared with those ofcontrol animals at the 48th h *** and EC were also significantly reducedafter severe burns,consistent with the trend ofgastric acid production *** Gastric acid production,as wellas GMBF and EC was predominantly decreased in the early postburn stage,suggesting that gastricmucosal ischemia and hypoxia with resultantdisturbance in energy metabolism,but notgastric acid proper,might be the decisive factorin the pathogenesis of AGMl after thermalinjury,and that the preventive use of anti-aciddrugs during burn shock period wasunreasonable in some ***,taking effective measures to improve gastricmucosal blood perfusion as early as possiblepostburn might be more preferable for the AGMlprevention and treatment.

关键词： Subject headings gastric mucosal lesions gastric acid burn shock

Ab initio STUDIES ON MAGNETISM OF 3d TRANSITION METAl DIMERS

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Acta Metallurgica Sinica(English letters) 2007年第5期20卷 341-346页

作者： J.H. Gu Z.l. zhu School of Physical Engineering and Material Physics laboratory Zhengzhou University Zhengzhou 450052 China

Ab initio calculations with the self-consistent full-potential linearized augmented-plane-wave method （FlAPW）, under generalized gradient approximation, have been carried out to describe the electronic and magnetic properties of 3d transition metal dimers. It predicted the antiferromagneticity of Cr2 and ferromagneticity of other species. The Mn2 dimer was shown to be ferromagnetic coupling with a local magnetic moment of 5μB. retaining the value of its free atom state. The V2 and Ni2 exhibited low spin-polarization with local magnetic moment of only 1μB per atom. On the other hand, Fe2 and Co2 were highly spin-polarized with local magnetic moments of 3 and 2μB.

关键词： magnetism 3d transition metal dimer ab initio calculation

EFFECT OF NANOCRYSTAllIZATION ON THE SCAlING OF NiAl AT 1000℃ IN AIR

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Acta Metallurgica Sinica(English letters) 2002年第1期15卷 77-80页

作者： S.l. Yang Fuhui Wang S.l. zhu State Key laboratory for Corrosion and Protection Institute of Metal Research The Chinese Academy of Sciences Shenyang 110016 China

The oxidation behavior of a magnetron sputtered nanocrystalline NiAl coating was investigated at 1000℃ in air. Comparing with cast NiAl and NiAl-0.1at.%Y alloys reveals influences of nanocrystallization as well as yttrium addition on the oxidation behavior of NiAl. Results show that a phase transformation from metastable θ-Al2O3 to stable a-Al2O3 occurred in scales, which was accelerated by the microcrystallization and retarded by the addition of Y. The addition of Y as well as the nanocrystallization reduced the void formation at the interface between the scale and the substrate.

关键词： nanocrystalline NiAl NiAlY oxidation

Novel heating-and deformation-induced phase transitions and mechanical properties for multicomponent Zr_(50)M_(50),Zr_(50)(M,Ag)_(50)and Zr_(50)(M,Pd)_(50)(M=Fe,Co,Ni,Cu)amorphous alloys

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Journal of Materials Science & Technology 2022年第9期104卷 109-118页

作者： J.Ding A.Inoue F.l.Kong S.l.zhu Y.l.Pu E.Shalaan A.A.Al-Ghamdi A.l.Greer School of Materials Science and Engineering Tianjin UniversityTianjin 300072China International Institute of Green Materials Josai International UniversityTogane 283-8555Japan Institute of Massive Amorphous Alloy Science China University of Mining TechnologyXuzhou 221116China Department of Physics King Abdulaziz UniversityJeddah 22254Saudi Arabia MISiS National University of Science and TechnologyMoscow 119049Russia School of Materials Science and Engineering Lanzhou Jiaotong UniversityLanzhou 730070China Department of Materials Science and Metallurgy University of CambridgeCambridge CB30FSUK

Multicomponent alloys of Zr_(50)M_(50),Zr_(50)(M,Ag)_(50)and Zr_(50)(M,Pd)_(50)(M=Fe,Co,Ni,Cu)can be melt-spun to obtain amorphous *** maximum thickness for fully amorphous ribbons varies with composition in the range 34-53μ*** contrast,fully amorphous ribbons are not obtainable for binary Zr_(50)Ni_(50)or ternary Zr_(50)(Ni,Cu)_(50)***-induced crystallization occurs through:two stages of amorphous[am]→[~(am')+B2]→[B2+B33]for Zr_(50)M_(50);and[am]→[am'+B2]→[B2+AgZr]for Zr_(50)(M,Ag)_(50);and a single stage of[am]→[B2]for Zr_(50)(M,Pd)_(50),while no B2 phase is formed for the binary and ternary Zr_(50)Q_(50)(Q=Ni or/and Cu)***-spun amorphous ribbons have good bending ***,Zr_(50)M_(50)ribbons in tension show 0.22-0.28%plastic elongation and work-hardening(the yield stress is~820 MPa,the fracture stress is~1200 MPa).When cold-rolled at room temperature to 30%reduction in thickness,Zr_(50)M_(50)ribbons show 10%increase in hardness,while retaining good bending ***-rolling induces precipitation of spheroidal B2 and irregular B33 particles,while deformation in tension induces B2,B33 and also plate-like monoclinic *** B2 and B33 particles form by polymorphic transformation,and include a high density of internal *** novel deformationinduced precipitation has not been recognized for any Zr_(50)Q_(50)binary or ternary *** new multicomponent systems are encouraging for future progress as structural amorphous alloys.

关键词： Multicomponent Microstructure Mechanical properties Phase transition Amorphous alloy

A prospective study:intraoperative ^(125)I radioactive seed implant therapy in advanced esophageal squamous cell carcinoma

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Journal of Nanjing Medical University 2009年第5期23卷 335-339页

作者： Jin lü Xiufeng Cao Bin zhu lü Ji Oncology Center Surgery of Nanjing First Hospital Affiliated to Nanjing Medical University and Oncology Center of Nanjing Medical University Nanjing 210006China

Objective： To investigated the role of intraoperative iodine-125 （125I） brachytherapy as a treatment option for advanced thoracic esophageal squamous cell carcinoma （ESCC）. Methods： Using preoperative computed tomography （CT）-based staging criteria, between 2000 and 2008, 298 patients with ESCC （stage Ⅱ-Ⅲ） were enrolled in this prospective study. With informed consent, patients were randomized into two groups： intraoperative ^125^I seed implantation and surgery alone （control group）. Twenty to forty 125I seeds （0.5 mCi per seed）, with a total activity in 10-30 mCi, and a matched peripheral dose （MPD） of 60-70 Gy, were implanted under direct visualization. The surgical procedure used in this study was either a radical resection, which involved an esophagectomy through a left thoracotomy with two-field lymphadenectomy, or palliative resection. The postoperative complications were observed and recorded. The location and quality assessment of J25I seeds were assessed using CT scans or X-ray imaging. The short-term efficacy was evaluated according to WHO criteria. The 1, 3, 5 and 7-year survival rates were determined on follow-up. Results： There was no displacement or loss of 125I seeds. The local recurrence rates in the intraoperative 125I seed implantation group and control group were 14.9% and 38.7%, respectively （P 〈 0.05）. An objective response rate of 92% was observed in the seed implant group, which was significantly higher than 0% in the control group （P 〈 0.05）. There was no significant difference between the two groups when comparing of complications （P 〉 0.05）. The 1-year survival rate of the two groups were not significantly different （P 〉 0.05）. However, the 3, 5 and 7-year survival rates in the united 125I group （64%, 55.3% and 8%, respectively） were statistically different from those in the control group （52%, 29.1% and 1.4%,respectively）（P 〈 0.05）. Conclusion： Intraoperative 125I seed implantation is safe and effective for advanced ESCC. Seed implantation

关键词： esophageal squamous cell carcinoma 125I radioactive seed brachytherapy esophagectomy

light-weighting in aerospace component and system design

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Propulsion and Power Research 2018年第2期7卷 103-119页

作者： l.zhu N.li P.R.N.Childs Imperial College london London SW72AZUnited Kingdom

light-weighting involves the use of advanced materials and engineering methods to enable structural elements to deliver the same,or enhanced,technical performance while using less *** concept has been extensively explored and utilised in many industries from automotive applications to fashion and packaging and offers significant potential in the aviation *** implementations of light-weighting have involved use of high performance materials such as composites and optimisation of structures using computational aided engineering approaches with production enabled by advanced manufacturing methods such as additive manufacture,foam metals and hot *** paper reviews the principal approaches used in light-weighting,along with the scope for application of light-weighting in aviation applications from power-plants to airframe components.A particular area identified as warranting attention and amenable to the use of lightweighting approaches is the design of solar powered aircraft *** high aspect ratio typically used for these can be associated with insufficient stiffness,giving rise to non-linear deformation,aileron reversal,flutter and rigid-elastic *** applications considered include ultralight aviation components and sub-systems,UAVs,and *** optimisation approaches can be applied to optimise the layout of structural elements,as well as geometrical parameters in order to maximise structural stiffness,minimise mass and enable incorporation of energy storage *** use of additive manufacturing technologies,some capable of producing composite or multi-material components is an enabler for light-weighting,as features formally associated with one principal function can be designed to fulfil multiple functionalities。

关键词： light-weighting aviation High performance lightweight materials Numerical structural optimization Advanced manufacturing

Borofutus, a new genus of Boletaceae from tropical Asia: phylogeny, morphology and taxonomy

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Fungal Diversity 2013年第1期58卷 215-226页

作者： Md.Iqbal Hosen Bang Feng Gang Wu Xue Tai zhu Yan Chun li zhu l.Yang Key laboratory of Biodiversity and Biogeography Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina University of Chinese Academy of Sciences Beijing 100049China

A new monotypic genus in the Boletaceae,Borofutus,typified by ***,is described using morphological and molecular *** is a putatively ectomycorrhizal fungus associated with Shorea *** is characterized by the combination of the following characters:basidiomata small to medium-sized;pileus grayish brown to cocoa brown;hymenophore subdecurrent,cream then golden brown,with broad,nearly hexagonal pores;basidiospores purple to purplish red in H2O,ornamented with irregular to regular shallow pits;cystidia lageniform,*** is sister to Spongiforma in molecular phylogenetic analyses using DNA nucleotide sequences of single or multiple loci.A description,line drawings,phylogenetic placement and comparison with allied taxa are presented herein.

关键词： Boletes Dipterocarpaceae Multiple gene analysis New fungal taxon

The genus Phylloporus (Boletaceae, Boletales) from China: morphological and multilocus DNA sequence analyses

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Fungal Diversity 2013年第1期58卷 73-101页

作者： Nian-Kai Zeng li-Ping Tang Yan-Chun li Bau Tolgor Xue-Tai zhu Qi Zhao zhu l.Yang Key laboratory of Biodiversity and Biogeography Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China Department of Pharmacy Hainan Medical UniversityHaikou 571101China Institute of Mycology Jilin Agriculture UniversityChangchun 130118China Graduate University of Chinese Academy of Sciences Beijing 100039China

Species of the genus Phylloporus in China were investigated based on morphology and molecular phylogenetic analysis of a three-locus(nrlSU,ITS and tef-1a)DNA sequence ***-one phylogenetic species were recognized among the studied *** of them are described as new:***,***,***,***,***,***,and *** addition,four of them correspond with the previous morphology-based taxa:***,***,***,and *** remaining ten phylogenetic species were not described due to the paucity of the materials.A key to the Chinese morphologically recognizable taxa was provided.A preliminary biogeographical analysis showed that(1)Pylloporus species in East Asia and Southeast Asia are mostly closely related,(2)species pairs or closely related species of Phylloporus between East Asia and North/Central America are relatively common,and(3)the biogeographic relationship of Phylloporus between East Asia and Europe was supported by only a single species ***,no taxa common either to both Europe and East Asia,or to both East Asia and North/Central America,were *** look to have taxa from both sides of the Pacific and Europe/Asia though.

关键词： Biogeography New taxa Phylogenetic species Species diversity Taxonomy