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Chinese Medical Journal 2014年第8期127卷 1590-1591页

作者： Liu Mei Wang Jianhua Ding Guichun Duan Yaqi Sun pengfei Jian Wenhao Department of Ultrasound General Hospital of Beijing Military Command of People's Liberation Army Beijing 100700 China

Patent foramen ovale （PFO）, a congenital cardiac lesion that persists into adulthood, has become the subject of much clinical interest. PFO has been implicated in several serious clinical syndromes, including paradoxical systemic emboli （which contribute to ischemic stroke）, myocardial infarction, and complications of pulmonary embolism. Currently, two-dimensional transesophageal echocardiography （TEE） is the standard procedure for diagnosing PFO. The diameter and contrast score have been used to size the PFO.~ None of these techniques is optimal as they are all indirect ways of measuring PFOs. Few data exist on the relation between stroke risk, anatomical characteristics, and physiological behavior. The purpose of our study therefore was to explore the clinical feasibility of sizing or displaying the morphology and physiological behavior of PFOs using three-dimensional TEE.

关键词： three-dimensional echocardiography patent foramen ovale diagnosis

Establishment and evaluation of an immortalized steroidogenic goat granulosa cell line as a model system to study the endoplasmic reticulum(ER)-stress response on steroidogenesis

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Establishment and evaluation of an immortalized steroidogeni...

变电站局部放电的定向天线多方位检测定位方法

中国畜牧兽医学会兽医产科学分会第十三次学术研讨会

作者：杨迪琦王磊 pengfei Lin Tingting Jiang Nan Wang Fan Zhao Huatao Chen Keqiong Tang Dong zhou Aihua Wang 靳亚平 Key Laboratory of Animal Biotechnology of the Ministry of Agriculture Northwest A&F University College of Veterinary Medicine Northwest A&F University

Under the support of granulosa cells and theca cells,the ovaries are responsible for producing oocytes and secreting sex steroids such as estrogen and *** reticulum stress(ERS) plays an important role in follicle atresia and embryo *** this study,goat granulosa cells were isolated from medium-sized(4-6 mm) healthy *** primary granulosa cells were immortalized by transfection with human telomerase reverse transcriptase(hTERT) to establish a goat granulosa cell line(hTERT-GGCs).Test results showed that hTERT-GGCs expressed hTERT,and a relatively long telomere existed at passage ***,the hTERT-GGCs expressed gonadotropin receptors CYP11A1,StAR and CYP19A1,which are involved in *** addition,the concentration of progesterone was detectable in *** the proliferation potential of hTERT-GGCs significantly improved,there was no evidence to suggest that the hTERT-GGCs are *** addition,thapsigargin(Tg)treatment led to a significant decrease in the progesterone concentration and the expression of steroidogenic enzyme in a dose-dependent *** summary,in this study we successfully generated a stable goat granulosa cell *** this cell line we found that Tg induced ERS,which reduced progesterone production and steroidogenic enzyme expression in *** studies may benefit from using this cell line as a model to explore the molecular mechanism regulating steroidogenesis and apoptosis in goat granulosa cells.

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高电压技术 2017年第5期43卷 1476-1484页

作者：周文俊李鹏飞杨帅刘宇舜田妍王勇武汉大学电气工程学院武汉430072 广州供电局有限公司广州510620

为提高变电站中高压设备局部放电(PD)的3维定位精度,开展了采用定向天线多方位检测的PD定位方法研究。研究了基于2支定向天线旋转检测的PD定位原理,分析了在单点旋转检测定位时的局限性,提出了多方位检测的定位方法。利用特高频信号首... 详细信息

为提高变电站中高压设备局部放电(PD)的3维定位精度,开展了采用定向天线多方位检测的PD定位方法研究。研究了基于2支定向天线旋转检测的PD定位原理,分析了在单点旋转检测定位时的局限性,提出了多方位检测的定位方法。利用特高频信号首波互相关算法进行时延估计,结合网格搜索法和粒子群寻优算法求解非线性方程组实现精准定位。并在220 kV变电站模拟了PD源的定位试验。结果表明:与全向天线定位方法相比,定向天线提升了微弱信号的检测能力,抑制了信号传播多路径效应,多方位检测的定位方法有效提高了变电站内PD的3维定位精度。研究结果对变电站内PD的精准定位具有工程实用价值。

关键词：局部放电定位变电站定向天线多方位检测首波互相关算法

Chemical constituents from Murraya tetramera Huang

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Journal of Chinese Pharmaceutical Sciences 2016年第3期25卷 201-205页

作者：周颖王文光屠鹏飞姜勇北京大学医学部药学院天然药物及仿生药物国家重点实验室北京100191

The aim of this study is to perform a phytochemical investigation of the aerial parts of Murraya tetramera Huang. Nine compounds were isolated by silica gel and Sephadex LH-20 chromatography, together with preparative TLC and HPLC methods. By analysis of the MS and NMR spectroscopic data and comparison with those in literature, these nine compounds were identified as 3,3＇-[oxybis（methylene）]bis（9-methoxy-9H-carbazole）（1）, murrastifoline B（2）, murrayaquinone A（3）, 2,4-dimethoxyphenol（4）, 1,2-dimethoxy-4-nitrobenzene（5）, 3-methylanisole（6）,（–）-syringaresinol-4-O-β-D-glucopyranoside（7）, β-sitosterol（8）, and octadecanyl-3-methoxy-4-hydroxylbenzeneacrylate（9）, respectively. Among them, compounds 4–6 and 9 were described from the genus Murraya for the first time, and compounds 2–9 were isolated from M. tetramera for the first time.

关键词： Rutaceae Murraya tetramera Chemical constituents

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豫南地区夏季绿肥品种筛选与冬小麦轮作

浙江农业科学 2024年第8期65卷 1957-1962页

作者：丁丽张琳杜光辉张丽霞史鹏飞聂良鹏凌敬伟潘兹亮吕玉虎信阳市农业科学院河南信阳464000

在信阳市种植6个夏季绿肥品种,设接种和不接种根瘤菌2个水平、共12个处理进行小区种植试验。通过种植筛选适宜冬小麦减肥生产的夏季绿肥品种,为翻压利用做准备。从多方面对不同夏季绿肥品种进行综合评价。结果表明:12个处理的出苗期差... 详细信息

在信阳市种植6个夏季绿肥品种,设接种和不接种根瘤菌2个水平、共12个处理进行小区种植试验。通过种植筛选适宜冬小麦减肥生产的夏季绿肥品种,为翻压利用做准备。从多方面对不同夏季绿肥品种进行综合评价。结果表明:12个处理的出苗期差别不大,巨丰和汾豆牧绿2号现蕾期最早,田菁现蕾期最晚。汾豆牧绿2号始花期最早,田菁始花期最晚。汾豆牧绿2号盛花期最早,田菁盛花期最晚,但均能在8月底压青沤肥。盛花期鲜草产量差异大,接种根瘤菌的田菁鲜草产量最高,巨丰和郑1307植株氮磷钾的养分含量综合比较最好。氮磷钾的养分积累量均以接种根瘤菌的田菁最高。接种根瘤菌的田菁能降低土壤温度,提高土壤湿度。增加土壤稳定性和抗风蚀能力,更能提高土壤肥力。初步筛选出与冬小麦轮作的夏季绿肥首选品种为田菁(接种根瘤菌)。

关键词：绿肥品种根瘤菌农艺性状鲜草产量养分含量筛选

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基于AHP的海事巡逻船配置

大连海事大学学报 2010年第4期36卷 14-16页

作者：黄鹏飞周建文李子富集美大学航海学院福建厦门361021

为更好地对海事巡逻船进行科学配置,以福建海事局为例,针对福建海事局海事巡逻船配置现状,根据《海事船舶配备管理规定》,利用层次分析法(AHP),综合考虑福建海事局所辖水域的配置因素,得出该水域海事巡逻船合理的配置结构.

关键词：海事巡逻船配置结构层次分析法(AHP)

A review of progress in coupled ocean-atmosphere model developments for ENSO studies in China

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Journal of Oceanology and Limnology 2020年第4期38卷 930-961页

作者： ZHANG Rong-Hua YU Yongqiang SONG Zhenya REN Hong-Li TANG Youmin QIAO Fangli WU Tongwen GAO Chuan HU Junya TIAN Feng ZHU Yuchao CHEN Lin LIU Hailong LIN pengfei WU Fanghua WANG Lin Key Laboratory of Ocean Circulation and Waves Institute of Oceanologyand Center for Ocean Mega-ScienceChinese Academy of SciencesQingdao 266071China Laboratory for Ocean and Climate Dynamics Pilot National Laboratory for Marine Science and TechnologyQingdao 266237China Center for Excellence in Quaternary Science and Global Change Chinese Academy of SciencesXi’an 710061China University of Chinese Academy of Sciences Beijing 100049China LASG Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100049China First Institute of Oceanography Ministry of Natural ResourcesQingdao 266061China Laboratory for Regional Oceanography and Numerical Modeling Pilot National Laboratory for Marine Science and TechnologyQingdao 266237China Key Laboratory of Marine Science and Numerical Modeling(MASNUM) Ministry of Natural ResourcesQingdao 266061China National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology Qingdao 266061China State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China Laboratory for Climate Studies and CMA-NJU Joint Laboratory for Climate Prediction Studies National Climate CenterChina Meteorological AdministrationBeijing 100081China Environmental Science and Engineering University of Northern British ColumbiaBritish Columbia V2N 4Z9Canada State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Key Laboratory of Meteorological Disaster Ministry of Education(KLME)and Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD)Nanjing University of Information Science and TechnologyNanjing 210044China Beijing Climate Center China Meteorological AdministrationBeijing 100081China

El Nino-Southern Oscillation(ENSO) is the strongest interannual signal that is producedby basinscale processes in the tropical Pacific,with significant effects on weather and climate *** the past,extensive and intensive international efforts have been devoted to coupled model developments for ENSO studies.A hierarchy of coupled ocean-atmo sphere models has been formulated;in terms of their complexity,they can be categorized into intermediate coupled models(ICMs),hybrid coupled models(HCMs),and fully coupled general circulation models(CGCMs).ENSO modeling has made significant progress over the past decades,reaching a stage where coupled models can now be used to successfully predict ENSO events 6 months to one year in ***,ENSO exhibits great diversity and complexity as observed in nature,which still cannot be adequately captured by current state-of-the-art coupled models,presenting a challenge to ENSO *** primarily reviewed the long-term efforts in ENSO modeling continually and steadily made at different institutions in China;some selected representative examples are presented here to review the current status of ENSO model developments and applications,which have been actively pursued with noticeable progress being made *** ENSO simulations are very sensitive to model formulations and process representations etc.,dedicated efforts have been devoted to ENSO model developments and ***,different ocean-atmosphere coupled models have been available in China,which exhibit good model performances and have already had a variety of applications to climate modeling,including the Coupled Model Intercomparison Project Phase 6(CMIP6).Nevertheless,large biases and uncertainties still exist in ENSO simulations and predictions,and there are clear rooms for their improvements,which are still an active area of researches and ***,model performances of ENSO simulations are assessed in terms of advantages and disadvantage

关键词： El Niño-Southern Oscillation(ENSO) coupled ocean-atmosphere models simulations and predictions model biases and uncertainties

金融中介与经济增长质量——基于中国省级样本的经验研究

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经济评论 2017年第5期 64-78页

作者：随洪光段鹏飞高慧伟周瑾山东大学经济学院山东省淄博市临淄区人民检察院

本文利用中国大陆28个省级样本2001-2015年的数据,考察了金融中介对经济增长质量的影响。结果表明:金融中介发展显著提升了经济增长的质量。在资金吸纳环节,动员社会资金功能与增长质量正相关,其贡献主要来自对增长稳定性的提升;动员居... 详细信息

本文利用中国大陆28个省级样本2001-2015年的数据,考察了金融中介对经济增长质量的影响。结果表明:金融中介发展显著提升了经济增长的质量。在资金吸纳环节,动员社会资金功能与增长质量正相关,其贡献主要来自对增长稳定性的提升;动员居民储蓄功能与增长质量负相关,其不利影响主要来自对增长可持续性的冲击。在资金投放环节,投资转化功能与增长质量正相关,显著提升了增长的可持续性;资金配置功能与增长质量正相关,对增长效率、稳定性和可持续性均产生了积极影响。鼓励针对非居民的金融产品创新,适当放松资本充足率管制,提升非国有部门的授信比例,有助于提升经济增长的质量。

关键词：金融中介经济增长质量主成分分析法

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双模三维环境下的态势标绘技术研究

测绘科学技术学报 2016年第2期33卷 169-174,179页

作者：李鹏飞周杨许继伟胡校飞信息工程大学河南郑州450001

针对虚拟三维环境态势标绘存在精度低、交互操作难以控制的缺点,提出了一种双模三维环境下的态势标绘与显示技术。首先利用遥感正射影像和DEM制作立体辅助影像,构建由立体辅助影像对形成的真实三维环境,并将其与传统虚拟三维环境无缝集... 详细信息

针对虚拟三维环境态势标绘存在精度低、交互操作难以控制的缺点,提出了一种双模三维环境下的态势标绘与显示技术。首先利用遥感正射影像和DEM制作立体辅助影像,构建由立体辅助影像对形成的真实三维环境,并将其与传统虚拟三维环境无缝集成;利用立体辅助影像的高精度量测的特性,在真实三维环境中精确采集态势符号定位点,根据标绘规范形成三维态势符号;最后在虚拟三维环境中进行态势的逼真显示。实验结果表明:双模三维环境下的态势标绘技术能够有效避免三维符号与地形之间的混叠,提高态势标绘精度,是高分辨率遥感卫星影像的一种新应用模式。

关键词：态势标绘双模三维虚拟三维真实三维立体辅助影像

Selectivity of Parvalbumin B Protein Binding to Ca^(2+) and Mg^(2+) at an Ab Initio QM/MM Level Using the Reference-Potential Method

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Chinese Journal of Chemical Physics 2021年第6期34卷 741-750,I0002页

作者： Shuwei Jin Jia-Ning Wang Yuanfei Xue pengfei Li Ye Mei State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200062China NYU-ECNU Center for Computational Chemistry at NYU Shanghai Shanghai 200062China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China d.Silicon Therapeutics(Suzhou)Co. Ltd.Suzhou 215000China

Ion selectivity in protein binding sites is of great significance to biological *** additive force fields have been successfully applied to various protein-related studies,it is difficult to well capture the subtle metal-protein interaction for the prediction of ion selectivity,due to the remarkable polarization and charge transfer effect between the metals and the surrounding *** mechanics-based methods are well-suited for dealing with these systems,but they are too costly to apply in a direct *** this work,the reference-potential method(RPM)was used to measure the selectivity for calcium and magnesium cations in the binding pocket of parvalbumin B protein by calculating the free energy change associated with this substitution reaction at an ab initio quantum mechanics/molecular mechanics(QM/MM)*** alchemical transformations were performed at the molecular mechanics level,and the relative binding free energy was then corrected to the QM/MM level via thermodynamic *** this way,the free energy change at the QM/MM level for the substitution reaction was obtained without running the QM/MM simulations,thus remarkably enhancing the *** the reweighting process,we found that the selection of the QM region greatly affects the accuracy of the QM/MM *** particular,the charge transfer effect on the free energy change of a reaction cannot be neglected.

关键词： Selectivity Free energy Referece potential method