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Distinct but correct: generating diversified and entity-revised medical response

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Science China(Information Sciences) 2024年第3期67卷 94-113页

作者： Bin LI Bin SUN Shutao LI Encheng CHEN Hongru LIU Yixuan WENG Yongping BAI meiling HU College of Electrical and Information Engineering Hunan University School of Mathematics Sun Yat-sen University JD Technology National Laboratory of Pattern Recognition Institute of AutomationChinese Academy of Sciences Xiangya Hospital of Central South University Teaching and Research Section of Clinical Nursing Xiangya Hospital of Central South University

Medical dialogue generation(MDG) is applied for building medical dialogue systems for intelligent consultation. Such systems can communicate with patients in real time, thereby improving the efficiency of clinical diagnosis. However, predicting correct entities and correctly generating distinct responses remain a great challenge. Inspired by actual doctors’ responses to patients, we consider MDG a two-stage task: entity prediction and dialogue generation. For entity prediction, we design an ent-mac post pre-training strategy by leveraging external medical entity knowledge to enhance the pre-trained model. For dialogue generation, we propose an entity-aware fusion MDG method in which predicted entities are integrated into the dialogue generation model through different encoding fusion mechanisms, using information from different sources. Because the diverse beam search algorithm can produce responses with entities that deviate from the predicted entities, an entity-revised diverse beam search is proposed to correct the entities entailed in the generated responses and make the generated responses more distinct. The experimental results on the China Conference on Knowledge Graph and Semantic Computing 2021(A/B tests) and the International Conference on Learning Representations 2021(online test) datasets show that the proposed method outperforms several state-of-the-art methods, which demonstrates its practicability and effectiveness.

关键词： medical entity prediction ent-mac post pre-training strategy entity-aware fusion medical dialogue generation encoding fusion mechanism entity-revised diverse beam search

Biomimetic microchannel network with functional endothelium formed by sacrificial electrospun fibers inside 3D gelatin methacryloyl(GelMA)hydrogel models

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第1期25卷 79-96页

作者： Haoyu SUN Haiyang MA Li WANG Yang LIU Tian HOU Wenjie TANG Qing YU Meiwen AN meiling WEN Institute of Biomedical Engineering College of Biomedical EngineeringTaiyuan University of TechnologyTaiyuan030024China

Three-dimensional(3D)hydrogel models play a crucial role in tissue engineering for promoting tissue regeneration.A biomimetic microchannel network system in the 3D hydrogel model is necessary for optimal cellular *** report describes the preparation of a biomimetic hydrogel scaffold with an internal microchannel network,using electrospinning techniques and the sacrificial template method for 3D cell *** and cavities were created within the gelatin methacryloyl(GelMA)hydrogel by sacrificing polyvinyl alcohol(PVA)electrospun fibers(>10µm),resulting in the creation of microvessel-like *** characterizations,swelling properties,and biodegradation analysis were conducted to investigate the feasibility of a biomimetic microchannel network hydrogel scaffold for 3D cell culture *** to pure GelMA hydrogel,the hydrogel with microchannels promoted cell proliferation,adhesion,and endothelial tube ***,the results confirmed that the biomimetic microchannel network scaffold had a major impact on the distribution and arrangement of human umbilical vein endothelial cells(HUVECs)and can enable the formation of artificial microvasculature by the culture of HUVECs and cell media perfusion.

关键词： Biomimetic scaffold Photocrosslinking Microchannel network Tissue engineering Artificial microvascular

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基于鲨鱼优化算法的液压伺服系统自抗扰控制

电气传动 2019年第11期49卷 76-81页

作者：周美玲刘悦开封大学信息工程学院

针对冷轧机组液压伺服位置系统存在不一致性而引起两侧位置不同步的问题,提出一种基于改进鲨鱼优化(ISSO)算法的自抗扰同步控制方法。首先,建立了液压伺服位置同步系统的数学模型,并针对自抗扰控制器参数难以整定以至于影响同步控制精... 详细信息

针对冷轧机组液压伺服位置系统存在不一致性而引起两侧位置不同步的问题,提出一种基于改进鲨鱼优化(ISSO)算法的自抗扰同步控制方法。首先,建立了液压伺服位置同步系统的数学模型,并针对自抗扰控制器参数难以整定以至于影响同步控制精度的问题,通过引入反向学习综合策略和自学习系数,针对鲨鱼优化算法易陷入局部最优的问题进行了改进,并将改进后的鲨鱼优化算法用于自抗扰控制器的参数整定。最后,通过仿真验证了所提方法有效地减小了同步控制误差,且具有良好的抗扰动能力。

关键词：位置同步控制鲨鱼优化算法参数整定反向学习自学习系数

Preparation,Characterization and Catalytic Properties of Amphiphilic Cyclopalladated Polymers and Their Langmuir Blodgett(LB) Films

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Preparation,Characterization and Catalytic Properties of Amp...

Microstructure Characteristics and Elevated Temperature Mechanical Properties of a B Containedβ-solidifiedγ-TiAl Alloy

第十八届全国金属有机化学学术研讨会

作者： Zhen Liu meiling zhou Guoping Li Wenjian Xu 李铁生 Yangjie Wu 郑州大学化学与分子工程学院河南省化学与生物重点实验室

Palladium-catalyzed cross-coupling reactions have become an extremely powerful method in organic synthesis for the formation of carbon-carbon or carbon-heteroatom bonds. The heterogeneous catalysts are widely used in the industry because of facilitating product purification and catalyst recycling,but the reaction mechanism of these catalysts is not ***,the traditional methods of immobilized catalysts are doped into organic polymers,

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Journal of Wuhan University of Technology(Materials Science) 2024年第3期39卷 738-746页

作者：王秀琦 GUO Ruiqi 刘国怀 LI Tianrui YANG Yuxuan CHEN Yang XIN meiling WANG Zhaodong State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819China School of Materials Science and Engineering Harbin Institute of Technology at ShenzhenShenzhen 518055China School of Metallurgical Engineering Anhui University of TechnologyMaanshan 243000China

The improved microstructure and enhanced elevated temperature mechanical properties of Ti-44Al-5Nb-(Mo,V,B)alloys were obtained by vacuum arc re-melting(VAR)and primary annealing heat treatment(HT)of 1260℃/6 h/Furnace cooling(FC).The phase transformation,microstructure evolution and tensile properties for as-cast and HTed alloys were *** indicate that three main phase transformation points are determined,T_(eut)=1164.3℃,T_(γsolv)=1268.3℃and T_(βtrans)=1382.8℃.There are coarse lamellar colonies(300μm in length)and neighbor reticular B2 andγgrain(3-5μm)in as-cast alloy,while lamellar colonies are markedly refined and multi-oriented(20-50μm)as well as the volume fraction and grain sizes of equiaxedγand B2 phases(about 15μm)significantly increase in as-HTed *** transformations involvingα+γ→α+γ+β/B2 and discontinuousγcoarsening contribute to the above ***(1-3μm)act as nucleation sites forβ_(eutectic) and produce massiveβgrains with different orientations,thus effectively refining the lamellar colonies and forming homogeneous multi-phase *** curves show both the alloys exhibit suitable performance at 800℃.As-cast alloy shows a higher ultimate tensile stress of 647 MPa,while a better total elongation of more than 41%is obtained for as-HTed *** mechanical properties improvement is mainly attributed to fine,multi-oriented lamellar colonies,coordinated deformation of homogeneous multi-phase microstructure and borides within lamellar interface preventing crack propagation.

关键词： TiAl alloy phase transformation heat treatment boride microstructure mechanical properties

Key role of electron accessibility at the noble metal-free catalytic interface in hydrogen evolution reaction

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Nano Research 2024年第4期17卷 2538-2545页

作者： Dongchen Han Nanxing Gao Yuyi Chu Zhaoping Shi Ying Wang Junjie Ge meiling Xiao Changpeng Liu Wei Xing State Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China Laboratory of Advanced Power Sources Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China Jilin Province Key Laboratory of Low Carbon Chemical Power Sources Changchun 130022China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China

The reactant concentration at the catalytic interface holds the key to the activity of electrocatalytic hydrogen evolution reaction(HER),mainly referring to the capacity of adsorbing hydrogen and electron *** hydrogen adsorption free energy(ΔGH)as a reactivity descriptor,the volcano curve based on Sabatier principle is established to evaluate the hydrogen evolution activity of ***,the role of electron as reactant received insufficient attention,especially for noble metal-free compound catalysts with poor conductivity,leading to cognitive gap between electronic conductivity and apparent catalytic *** we successfully construct a series of catalyst models with gradient conductivities by regulating molybdenum disulfide(MoS_(2))electronic bandgap via a simple solvothermal *** demonstrate that the conductivity of catalysts greatly affects the overall catalytic *** further elucidate the key role of intrinsic conductivity of catalyst towards water electrolysis,mainly concentrating on the electron transport from electrode to catalyst,the electron accumulation process at the catalyst layer,and the charge transfer progress from catalyst to *** and experimental evidence demonstrates that,with the enhancement in electron accessibility at the catalytic interface,the dominant parameter governing overall HER activity gradually converts from electron accessibility to combination of electron accessibility and hydrogen adsorbing *** results provide the insight from various perspective for developing noble metal-free catalysts in electrocatalysis beyond HER.

关键词： conductivity molybdenum disulfide catalytic interface electron accessibility hydrogen evolution charge transfer.

Mo-La_2O_3阴极碳化层组织结构研究

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中国稀土学报 2010年第5期28卷 586-590页

作者：周文元张久兴周美玲相志磊北京工业大学材料科学与工程学院北京100022

采用高分辨透射/扫描电镜,X射线衍射和俄歇探针等分析手段对实用型的FU-6051电子管的碳化Mo-La2O3阴极显微组织结构进行了观察分析。碳化Mo-La2O3阴极碳化层为疏松多孔的Mo2C块状组织,其中有许多垂直于丝轴方向的晶界与孔洞串,相互贯通... 详细信息

采用高分辨透射/扫描电镜,X射线衍射和俄歇探针等分析手段对实用型的FU-6051电子管的碳化Mo-La2O3阴极显微组织结构进行了观察分析。碳化Mo-La2O3阴极碳化层为疏松多孔的Mo2C块状组织,其中有许多垂直于丝轴方向的晶界与孔洞串,相互贯通直至阴极表面。碳化层与芯部基体钼结合良好,两者间无明显的过渡层。活性物质La2O3在阴极的碳化层和基体中分布均匀,但在阴极表面有相当程度的富集。La2O3在碳化层中以两种方式存在:在晶界、孔洞中以微米级的颗粒富集,在Mo2C晶体内部弥散分布纳米级La2O3粒子。

关键词：镧钼阴极碳化层镧微观组织与结构

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CVD温度对钼沉积层组织及性能的影响

稀有金属材料与工程 2005年第12期34卷 1965-1968页

作者：马捷毕安园王从曾周美玲北京工业大学功能材料教育部重点实验室北京100022

介绍了化学气相沉积法(CVD)制备难熔金属钼膜层的原理和方法。以MoF_6和H_2为原料,采用化学气相沉积法在纯铜基体上沉积出难熔金属钼膜层。分析研究了沉积层的组织、结构和硬度。实验结果表明：沉积膜层显微组织随沉积温度变化而不同,... 详细信息

介绍了化学气相沉积法(CVD)制备难熔金属钼膜层的原理和方法。以MoF_6和H_2为原料,采用化学气相沉积法在纯铜基体上沉积出难熔金属钼膜层。分析研究了沉积层的组织、结构和硬度。实验结果表明：沉积膜层显微组织随沉积温度变化而不同,沉积温度较低时,沉积层显微组织为细晶层状结构,沉积层硬度可达677×9.8 MPa：沉积温度较高时,沉积层显微组织为致密的柱状晶,硬度稍高于一般烧结钼的硬度。

关键词：化学气相沉积钼显微组织

Simultaneously achieving high energy density and responsivity in submicron BaTiO_(3) film capacitors integrated on Si

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Journal of Advanced Ceramics 2024年第2期13卷 198-206页

作者： Jun Ouyang Yinxiu Xue Chuanqi Song meiling Yuan Kun Wang Yuyao Zhao Hongbo Cheng Hanfei Zhu Chao Liu Institute of Advanced Energy Materials and Chemistry School of Chemistry and Chemical EngineeringQilu University of Technology(Shandong Academy of Sciences)Jinan 250353China Key Laboratory of Key Film Materials&Application for Equipment School of Material Sciences and EngineeringXiangtan UniversityXiangtan 411105China School of Materials Science and Engineering Shandong UniversityJinan 250061China Academic Affairs Office Civil Aviation University of ChinaTianjin 300300China China Tobacco Shandong Industrial Co. Ltd.Jinan 250014China

In the research field of energy storage dielectrics,the“responsivity”parameter,defined as the recyclable/recoverable energy density per unit electric field,has become critically important for a comprehensive evaluation of the energy storage capability of a *** this work,high recyclable energy density and responsivity,i.e.,W_(rec)=161.1 J·cm^(-3) and ξ=373.8 J·(kV·m^(2))^(-1),have been simultaneously achieved in a prototype perovskite dielectric,BaTiO_(3),which is integrated on Si at 500℃ in the form of a submicron thick *** ferroelectric film features a multi-scale polar structure consisting of ferroelectric grains with different orientations and inner-grain ferroelastic domains.A LaNiO_(3) buffer layer is used to induce a{001}textured,columnar nanograin microstructure,while an elevated deposition temperature promotes lateral growth of the nanograins(in-plane diameter increases from~10-20 nm at lower temperatures to~30 nm).These preferably oriented and periodically regulated nanograins have resulted in a small remnant polarization and a delayed polarization saturation in the film’s P-E behavior,leading to a high recyclable energy ***,an improved polarizability/dielectric constant of the BaTiO_(3) film has produced a much larger maximum polarization than those deposited at lower temperatures at the same electric field,leading to a record-breaking responsivity for this simple perovskite.

关键词： energy storage energy density responsivity BaTiO_(3) dielectric capacitor Si