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An investigation of the morphodynamic change of reef islands under monochromatic waves

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Acta Oceanologica Sinica 2023年第7期42卷 41-50页

作者： Yu Yao Baobao Zhou zhongwei zhao Xianjin Chen Long Chen School of Hydraulic and Environmental Engineering Changsha University of Science and TechnologyChangsha 410114China Key Laboratory of Ocean and Marginal Sea Geology South China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 511458China Key Laboratory of Water-Sediment Sciences and Water Disaster Prevention of Hunan Province Changsha 410114China

The persistence and habitability of coral reef islands in future extreme oceanographic conditions has received increasing attention in the recent decade,concerning that the sea level rise(SLR)and more frequent and intense storms in the context of global climate change are expected to destabilize those ***,we conduct a set of wave-flume laboratory experiments focusing on the morphodynamic change of reef islands to varying ocean forcing conditions(wave height and SLR).Subsequently,a phase-resolving XBeach numerical model is adopted to simulate the monochromatic wave process and its associated sediment *** adopted model is also firstly validated by laboratory experimental results as reported in this *** is then used to examine the impacts of island morphological factors(island width,island height,island location and island side slope)on the island *** combined laboratory/physical and numerical experiment outputs suggest that reef islands can accrete vertically in response to the sea level rise and the increased storminess.

关键词： coastal morphodynamics sea level rise reef island wave-flume experiment XBeach model

Pull-through capacity of bolted thin steel plate

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Frontiers of Structural and Civil Engineering 2020年第5期14卷 1166-1179页

作者： zhongwei zhao Miao LIU Haiqing LIU Bing LIANG Yongjing LI Yuzhuo ZHANG School of Civil Engineering Liaoning Technical UniversityFuxin 123000China Department of Civil Engineering Shenyang Jianzhu UniversityShenyang 110168China

The loading capacity in the axial direction of a bolted thin steel plate was investigated.A refined numerical model of bolt was first constructed and then validated using existing experiment *** analysis was performed to reveal the influences of geometric parameters,including the effective depth of the cap nut,the yield strength of the steel plate,the preload of the bolt,and shear force,on the ultimate loading ***,an analytical method was proposed to predict the ultimate load of the bolted thin steel *** derived using the numerical and analytical methods were compared and the results indicated that the analytical method can accurately predict the pull-through capacity of bolted thin steel *** work reported in this paper can provide a simplified calculation method for the loading capacity in the axial direction of a bolt.

关键词： bolted thin steel plate refined numerical model loading capacity nonlinear spring element analytical method

An Interdisciplinary Perspective from the Earth Scientist's Periodic Table:Similarity and Connection between Geochemistry and Metallurgy

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Engineering 2020年第6期6卷 707-715页

作者： Fenglong Sun zhongwei zhao School of Metallurgy and Environment Central South UniversityChangsha 410083China Key Laboratory for Metallurgy and Material Processing of Rare Metals.Central South University Changsha 410083China

In 2003,Railsback proposed the Earth Scientist's Periodic Table,which displays a great deal of elemental geology information in accordance with the natural environment of the *** an applied science,metallurgy is based on mineral composition and element behavior,that is similar to *** this paper,connections and similarities between geology and metallurgy are identified,based on geochemical laws and numerous metallurgical *** obvious connection is that simple cations w让h high and low ionic potential are commonly extracted by hydrometallurgy,while those with intermediate ionic potential are extracted by *** addition,element affinity in geology is associated with element migration in metallurgic *** be specific,in pyrometallurgy,lithophile elements tend to gather in slags,chalcophile elements prefer the matte phase,siderophile elements are easily absorbed into metal melt,and atmophile elements readily enter the gas ***,in hydrometallurgy,the principles of hard/soft acids and bases(HSABs)offer an explanation of how precipitation and dissolution occur in different solutions,especially for fluoride and *** article provides many metallurgical examples based on the principles of geochemistry to verify these similarities and connections.

关键词： Metallurgy Geochemistry Periodic table Ionic potential Elemental affinity

A decomposing technique for scheelite concentrate and low-grade scheelite concentrate

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Rare Metals 2004年第2期23卷 115-119页

作者： HUO Guangsheng SUN Peimei LI Honggui LI Yunjiao zhao zhongwei SUN zhaoming LIU Maosheng School of Metallurgy Science and Engieering, Central South University, Changsha 410083, China School of Metallurgy Science and Engineering Central South University Changsha 410083 China

The effect of different decomposition conditions on tungsten recovery forscheelite concentrate has been examined. The results show that tungsten recovery can be more than98% under decomposing conditions as follows: the amount of caustic soda is 2.2 and 3.2 times oftheoretical respectively, ratio of water and ore is 0.7-0.8, temperature is 160℃, and preservationtime is 2.0 h for scheelite concentrate (63.21 % WO_3) and low grade scheelite concentrate (55.17%WO_3).

关键词： non-ferrous metallurgy caustic soda digestion scheelite concentrate lowgrade scheelite concentrat

Fucoidan-based dual-targeting mesoporous polydopamine for enhanced MRI-guided chemo-photothermal therapy of HCC via P-selectin-mediated drug delivery

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Asian Journal of Pharmaceutical Sciences 2022年第6期17卷 908-923页

作者： Gaofeng Shu Lin Shen Jiayi Ding Junchao Yu Xiaoxiao Chen Xiaoju Guo Enqi Qiao Yaning Chen Chenying Lu zhongwei zhao Yongzhong Du Minjiang Chen Jiansong Ji Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research Institute of Imaging Diagnosis and Minimally Invasive Intervention ResearchThe Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000China Department of radiology Lishui Hospital of Zhejiang UniversitySchool of MedicineLishui 323000China Institute of Pharmaceutics College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Shaoxing University School of Medcine Shaoxing 312000China

The development of novel theranostic agents with outstanding diagnostic and therapeutic performances is still strongly desired in the treatment of hepatocellular carcinoma(HCC).Here,a fucoidan-modified mesoporous polydopamine nanoparticle dual-loaded with gadolinium iron and doxorubicin(FMPDA/Gd^(3+)/DOX)was prepared as an effective theranostic agent for magnetic resonance imaging(MRI)-guided chemo-photothermal therapy of *** was found that FMPDA/Gd^(3+)/DOX had a high photothermal conversion efficiency of 33.4%and excellent T1-MRI performance with a longitudinal relaxivity(r1)value of 14.966 m M^(-1)·s^(-1).Moreover,the results suggested that FMPDA/Gd^(3+)/DOX could effectively accumulate into the tumor foci by dual-targeting the tumor-infiltrated platelets and HCC cells,which resulted from the specific interaction between fucoidan and overexpressed p-selectin *** excellent tumor-homing ability and MRI-guided chemo-photothermal therapy therefore endowed FMPDA/Gd^(3+)/DOX with a strongest ability to inhibit tumor growth than the respective single treatment ***,our study demonstrated that FMPDA/Gd^(3+)/DOX could be applied as a potential nanoplatform for safe and effective cancer theranostics.

关键词： Mesoporous polydopamine Fucoidan P-selectin target Platelets bridge Cancer theranostics

Minimally invasive interventional therapy for pain

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Journal of Interventional Medicine 2023年第2期6卷 64-68页

作者： Yingjie Hua Dan Wu Tian Gao Lu Liu Yanyu He Yiming Ding Qiaoying Rao Qiaohong Wu zhongwei zhao Department of Pain Medicine The Fifth Affiliated Hospital of Wenzhou Medical UniversityLishuiZhejiang Province323000China Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research LishuiZhejiang Province323000China

Pain interventional therapy,known as the most promising medical technology in the 21st century,refers to clinical treatment technology based on neuroanatomy,neuroimaging,and nerve block technology to treat pain *** with traditional destructive surgery,interventional pain therapy is considered a better and more economical choice of *** recent years,a variety of minimally invasive pain interventional therapy techniques,such as neuroregulation,spinal cord electrical stimulation,intervertebral disc ablation,and intrasheath drug infusion systems,have provided effective solutions for the treatment of patients with post-herpetic neuralgia,complex regional pain syndrome,cervical/lumbar disc herniation,and refractory cancer pain.

关键词： Interventional therapy Nerve regulation Spinal cord stimulation Discogenic pain Intrathecal drug delivery system

Expression of tumor necrosis factor related apoptosis inducing ligand receptor in glioblastoma

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Neural Regeneration Research 2008年第5期3卷 538-541页

作者： Dongling Gao zhongwei zhao Hongxin Zhang Lan Zhang Kuisheng Chen Yunhan Zhang Department of Pathology First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 Henan Province China

BACKGROUND： Receptors for tumor necrosis factor related apoptosis inducing ligand （TRAIL） include death receptor 4, death receptor 5, decoy receptor 1, and decoy receptor 2. Activation of death receptor 4 and 5 selectively kills tumor cells. OBJECTIVE： To detect TRAIL receptor expression in glioblastoma by immunohistochemistry and RT-PCR, and to compare this expression to that in normal brain tissue. DESIGN： Observational analysis. SETTING： Department of Pathology, the First Affiliated Hospital of Zhengzhou University; Henan Tumor Pathology Key Laboratory. PARTICIPANTS： Twenty-five patients （17 males and 8 females） who received glioblastoma resection were selected from the Fifth Affiliated Hospital of Zhengzhou University, between September 2003 to June 2004. All glioblastoma samples were diagnosed pathologically. Twenty patients （12 males and 8 females） with craniocerebral injury who received normal brain tissue resection were selected in the same time period. There were no significant differences in sex and age between glioblastoma patients or between craniocerebral injury patients （P 〉 0.05）. All patients and appropriate relatives provided informed consent, and this study was approved by the local research ethics committee. METHODS： Polyclonal antibody against TRAIL receptors and an immunohistochemical kit （batch number： 200502） were purchased from Boster Company, Wuhan. Immunohistochemistry： Expression of death receptor 4, death receptor 5, decoy receptor l, and decoy receptor 2 were observed in both glioblastoma and normal brain tissue. The experiment was performed according to the kit instructions, and positive staining was brown-yellow. Assessment： There were no positive signals （-）; weakly positive signals, positive cells 〈 25% （＋）; weakly positive signals, positive cells 25%-50% （＋＋）; strongly positive signals, positive cells 50%-75% （＋＋＋）; strongly positive signals, positive cells 〉 75% （＋＋＋＋）. Evaluation： Expression levels of TRAIL receptors were estimate

关键词： glioblastoma tumor necrosis factor related apoptosis inducing ligand apoptosis immunohistochemistry reverse transcription polymerase chain reaction

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家庭重构方法与历史人口学研究

世界历史 2011年第2期 96-101,160页

作者：赵中维澳大利亚国立大学人口与社会研究所

历史人口学一般被定义为使用常规与非常规人口技术对历史数据进行分析研究的学科。其研究的主要目的是获取历史上详细的人口信息,如人口规模、性别与年龄结构、出生、死亡、婚姻、人口迁移,并对包括以上人口特征及事件在内的人口变化进... 详细信息

历史人口学一般被定义为使用常规与非常规人口技术对历史数据进行分析研究的学科。其研究的主要目的是获取历史上详细的人口信息,如人口规模、性别与年龄结构、出生、死亡、婚姻、人口迁移,并对包括以上人口特征及事件在内的人口变化进行测量与分析。在历史人口学的发展中,家庭重构方法的使用及其推广起到了极大作用。本文对家庭重构方法及使用的资料、该方法在历史人口学研究中的应用与贡献,以及其他有关问题做一简要介绍。

关键词：家庭重构方法历史人口学教会登记

Healing Temperature of Hybrid Structures Based on Genetic Algorithm

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Transactions of Tianjin University 2016年第1期22卷 64-71页

作者：赵中伟陈志华刘红波 School of Civil Engineering Tianjin University Key Laboratory of Coast Civil Structure Safety of Ministry of Education Tianjin University

The healing temperature of suspen-dome with stacked arches(SDSA)and arch-supported single-layer lattice shell structures was investigated based on the genetic algorithm. The temperature field of arch under solar radiation was derived by FLUENT to investigate the influence of solar radiation on the determination of the healing temperature. Moreover, a multi-scale model was established to apply the complex temperature field under solar radiation. The change in the mechanical response of these two kinds of structures with the healing temperature was discussed. It can be concluded that solar radiation has great influence on the healing temperature, and the genetic algorithm can be effectively used in the optimization of the healing temperature for hybrid structures.

关键词： healing temperature genetic algorithm solar radiation strain energy multi-scale model multi-point constraint equation