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The Potassium Transporter AtKUP12 Enhances Tolerance to Salt Stress through the Maintenance of the K^(+)/Na^(+)Ratio in Arabidopsis

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Phyton-International Journal of Experimental Botany 2021年第2期90卷 389-402页

作者： Hua Zhang zhongmin yang Xilong You Youqiang Heng Yan Wang Xinjiang Key Laboratory of Biological Resources and Genetic Engineering College of Life Science and TechnologyXinjiang UniversityUrumqi830046China

Potassium(K^(+))is a necessary nutrient for plant growth and crop *** K^(+)transporter plays crucial roles in the absorption and transport of K^(+)in *** K^(+)transporters in Arabidopsis have been reported,but AtKUP12,which is a member of the KT/KUP/HAK family,has not yet been the subject of relevant in-depth *** the present study,we demonstrated that AtKUP12 plays a crucial role in K^(+)uptake in Arabidopsis under 100μM low-K^(+)and 125 mM salt stress ***12 transcripts were induced by K^(+)deficiency and salt *** analyzed the K^(+)uptake of AtKUP12 using the K^(+)uptake-deficient yeast R5421 and Arabidopsis mutant *** with AtKUP12 rescued the growth defect of mutant yeast and atkup12 mutant plants at the low-K^(+)concentration,which suggested that AtKUP12 might be involved in high-affinity K^(+)uptake in low-K^(+)*** comparison to the wild-type(WT)and atkup12-AtKUP12 complementation lines,atkup12 showed a dramatic reduction in potassium concentration,K^(+)/Na^(+)ratio,and root and shoot growth on 12-day-old seedlings under the salt conditions;however,there was no significant difference between the complementation and WT *** together,these results demonstrate that AtKUP12 might participate in salt tolerance in Arabidopsis through K^(+)uptake and K^(+)/Na^(+)homeostasis.

关键词： AtKUP12 atkup12 mutant K+uptake K^(+)/Na^(+)homeostasis salt tolerance

Wearable ultrasensitive and rapid human physiological monitoring based on microfiber Sagnac interferometer

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Science China(Information Sciences) 2024年第3期67卷 281-290页

作者： Xin WANG Hongyou ZHOU Meihua CHEN Yongcheng HE Zhishen ZHANG Jiulin GAN zhongmin yang State Key Laboratory Luminescent Materials and Devices Institute of Optical Communication MaterialsSpecial Glass Fiber and Device Engineering Technology Research and Development Center of Guangdong ProvinceGuangdong Provincial Key Laboratory of Fiber Laser Materials and Applied TechniquesSouth China University of Technology Guangdong-Hong Kong-Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology Foshan University

High-sensitive and fast-responding flexible strain sensors are essential for the smart wearable devices that precisely and dynamically perceive the weak deformations induced by human physiological signals. Here, a flexible strain sensor via polydimethylsiloxane(PDMS)-encapsulated microfiber Sagnac interferometer was designed and prepared for monitoring the human pulse signals and sound vibrations. The sensor achieved a record-breaking sensitivity(gauge factor, GF = 9977) and an extremely low detection limit(0.00025%) due to the strong polarization-dependent coupling effect in the microfiber coupler and the polarization-mixing effect in the Sagnac loop. The relative intensity demodulation method also enabled a fast response time of 10 μs. The wearable pulse measurements were implemented by attaching this flexible strain sensor directly to human skin at various locations and the waveform details were accurately captured. Taking advantage of the ultra-high sensitivity and fast response performance of the prepared sensor, the real-time dynamic acquisition of the underwater weak signal, such as the hydro-acoustic waves with a wide range of 20 Hz–16.86 k Hz, has been demonstrated. These initial results pave the way for a new and innovative category of underwater wearable devices with rapid detection of human physiological signals and weak environmental vibrations.

关键词： flexible strain sensor microfiber Sagnac interferometer underwater detection

Realization of one-dimensional 2^(n)-root topological states in photonic lattices

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Science China(Technological Sciences) 2024年第1期67卷 98-104页

作者： WEI RuiShan ZHANG QingLong yang DanDan HUANG XiongJian PAN QiWen KANG Juan QIU JianRong yang zhongmin DONG GuoPing State Key Laboratory of Luminescent Materials and Devices and Guangdong Provincial Key Laboratory of Fiber Laser Materials and Applied TechniquesGuangdong Engineering Technology Research and Development Center of Special Optical Fiber Materials and DevicesSchool of Materials Science and EngineeringSouth China University of TechnologyGuangzhou 510640China School of Physics and Optoelectronics South China University of TechnologyGuangzhou 510640China State Key Laboratory of Modern Optical Instrumentation College of Optical Science and EngineeringZhejiang UniversityHangzhou 310027China

Square-root topological insulators recently discovered are intriguing topological *** possess topological properties inherited from the squared Hamiltonian and exhibit double-band *** mechanism of the square root was generalized to 2^(n)-root topological insulators,giving rise to more band *** this study,we describe the experimental realization of onedimensional 2^(n)-root topological insulators in photonic waveguide arrays using the archetypical Su-Schrieffer-Heeger(SSH)*** edge states with tunable numbers are clearly observed under visible *** particular,we visualized the dynamic evolutions of the light propagation by varying the sample lengths,which further proved the localization and multiple numbers of edge states in 2^(n)-root topological *** experiment,which involves constructing 2^(n)-root topological photonic lattices in various geometric arrangements,provides a stable platform for studying topological states that exhibit a remarkable degree of flexibility and control.

关键词： 2^(n)-root topological insulators multiple edge states photonic waveguide arrays light dynamics

miR-126-5p affects the chemosensitivity of colorectal cancer cells by regulating SPRED1, ERK1/2 pathway and apoptosis

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Genes & Diseases 2023年第3期10卷 675-678页

作者： Mingshi Xu Gang Zhang Xiaofan Gu Fangqin Zhao zhongmin yang Xiongwen Zhang Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development School of Chemistry and Molecular EngineeringEast China Normal UniversityShanghai 200241China

Chemoresistance is still one of the main obstacles to treat colorectal cancer(CRC).Substantial studies on biomarkers related to chemoresistance have emerged in recent *** microRNAs(miRNA)have been reported to involved in drug resistance and CRC.1 MiR-126-5p participates in malignant behaviors of numerous cancers.2,3 However,it is not known if miR-126-5p participates in multidrug resistance in ***,the impact of miR-126-5p on drug resistance of CRC and its drug resistance mechanism have not been reported.

关键词： colorectal miR cancer

In situ instant generation of an ultrabroadband near-infrared emission center in bismuth-doped borosilicate glasses via a femtosecond laser

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Photonics Research 2019年第3期7卷 300-310页

作者： LIPING WANG JIANGKUN CAO YAO LU XIAOMAN LI SHANHUI XU QINYUAN ZHANG zhongmin yang MINGYING PENG State Key Laboratory of Luminescent Materials and Devices Guangdong Engineering Technology Research and Development Center of Special Optical Fiber Materials and Devices Guangdong Provincial Key Laboratory of Fiber Laser Materials and Applied Techniques School of Materials Science and Engineering South China University of Technology Department of Orthopedics Zhujiang Hospital Southern Medical University School of Physics and Physical Engineering Shandong Provincial Key Laboratory of Laser Polarization and Information TechnologyQufu Normal University

Bismuth(Bi)-doped photonic materials, which exhibit broadband near-infrared(NIR) luminescence(1000–1600 nm), are evolving into interesting gain media. However, the traditional methods have shown their limitations in enhancing Bi NIR emission, especially in the microregion. Consequently, the typical NIR emission has seldom been achieved in Bi-doped waveguides, which highly restricts the application of Bi-activated ***, superbroadband Bi NIR emission is induced in situ instantly in the grating region by a femtosecond(fs)laser inside borosilicate glasses. A series of structural and spectroscopic characterizations are summoned to probe the generation mechanism. And we show how this novel NIR emission in the grating region can be enhanced significantly and erased reversibly. Furthermore, we successfully demonstrate Bi-activated optical *** results present new insights into Bi-doped materials and push the development of broadband waveguide amplification.

关键词： ultrabroadband near-infrared emission center bismuth-doped borosilicate glasses via a femtosecond laser

Dynamic gain driven mode-locking in GHz fiber laser

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Light(Science & Applications) 2024年第11期13卷 2715-2725页

作者： Xuewen Chen Wei Lin Xu Hu Wenlong Wang Zhaoheng Liang Lin Ling yang yang Yuankai Guo Tao Liu Dongdan Chen Xiaoming Wei zhongmin yang School of Physics and Optoelectronics State Key Laboratory of Luminescent Materials and DevicesGuangdong Engineering Technology Research and Development Center of Special Optical Fiber Materials and DevicesGuangdong Provincial Key Laboratory of Fiber Laser Materials and Applied TechniquesSouth China University of TechnologyGuangzhouChina Research Institute of Future Technology South China Normal UniversityGuangzhouGuangdongChina

Ultrafast lasers have become powerful tools in various fields,and increasing their fundamental repetition rates to the gigahertz(GHz)level holds great potential for frontier scientific and industrial *** various schemes,passive mode-locking in ultrashort-cavity fiber laser is promising for generating GHz ultrashort pulses(typically solitons),for its simplicity and ***,its pulse energy is far lower than the critical value of the existing theory,leading to open questions on the mode-locking mechanism of GHz fiber ***,we study the passive mode-locking in GHz fiber lasers by exploring dynamic gain depletion and recovery(GDR)effect,and establish a theoretical model for comprehensively understanding its low-threshold mode-locking mechanism with multi-GHz fundamental repetition ***,the GDR effect yields an effective interaction force and thereby binds multi-GHz solitons to form a counterpart of soliton *** is found that the resulting collective behavior of the solitons effectively reduces the saturation energy of the gain fiber and permits orders of magnitude lower pulse energy for continuous-wave mode-locking(CWML).A new concept of quasi-single soliton defined in a strongly correlated length is also proposed to gain insight into the dynamics of soliton assembling,which enables the crossover from the present mode-locking theory to the existing ***,two distinguishing dynamics of Q-switched mode-locking that respectively exhibit rectangular-and Gaussian-shape envelopes are theoretically indicated and experimentally verified in the mode-locked GHz fiber laser through the measurements using both the standard real-time oscilloscope and emerging time-lens *** on the proposed criterion of CWML,we finally implement a GDR-mediated mode-locked fiber laser with an unprecedentedly high fundamental repetition rate of up to 21 GHz and a signal-tonoise ratio of 85.9 dB.

关键词： fiber mode locking

Development of Mathematical Model on Preparation of Functionally Graded Material by Co-sedimentation

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Journal of Materials Science & Technology 2001年第2期17卷 275-277页

作者： zhongmin yang, Lianmeng ZHANG and Qiang SHEN Institute of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, China Wuhan Univ Technol Inst Mat Sci & Engn Wuhan 430070 Peoples R China

From the process of sedimentation the mathematical relationships among deposition Volume and powder properties as well as sedimentation parameters were deduced. Based on the formula a mathematical model was set up and simulated through the computer. At last the validity of mathematical model was supported by the representative experiment on Ti-Mo system FGM prepared by co-sedimentation.

关键词： Co Mo Development of Mathematical Model on Preparation of Functionally Graded Material by Co-sedimentation

Switchable photothermal conversion efficiency for reprogrammable actuation

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npj Flexible Electronics 2023年第1期7卷 70-78页

作者： Yongcheng He Haojun Liu Jiajia Luo Nuo Li Lihua Li Puxian Xiong Jiulin Gan zhongmin yang State Key Laboratory Luminescent Materials and Devices Institute of Optical Communication MaterialsSpecial Glass Fiber and Device Engineering Technology Research and Development Center of Guangdong ProvinceGuangdong Provincial Key Laboratory of Fiber Laser Materials and Applied TechniquesSouth China University of Technology510641 GuangzhouChina Future Institute of Technology School of Information and Optoelectronic Science and EngineeringSouth China Normal University510515 GuangzhouChina

Reprogrammable soft matter brings flexibility to soft robots so that they can display various motions,which is flourishing in soft ***,the reprogramming of photoresponsive materials used in soft robots is time-consuming using existing *** this study,we promote a strategy for rapid reprogramming via switchable photothermal conversion efficiency(PCE).The liquid crystalline elastomers doped with semiconductor bismuth compounds(Bi-LCE)used in this work exhibited large photothermal actuation with over 35%shrinkage in 5 s at high PCE state,which demonstrated little deformation at low PCE ***,the material was capable of being reprogrammed up to 10 times,with only 20 min required for one PCE reversible *** on this switchable PCE effect,the same Bi-LCE film displayed various shape changes through different programmable ***,a reprogrammable hollow tube made of PCE reprogrammable materials could tune the diameter,cross-section configuration,and surface morphology,which was crucial for microfluidics *** materials provide endless possibilities for reusability and sustainability in robotics.

关键词： programming consuming bismuth

Aggregated carbon dots-loaded macrophages treat sepsis by eliminating multidrug-resistant bacteria and attenuating inflammation

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Aggregate 2023年第1期4卷 184-198页

作者： Lihua Li Lingling Chen Yao Lu Binglin Li Rong Hu Ling Huang Tao Zhang Xiaoming Wei zhongmin yang Chuanbin Mao State Key Laboratory of Luminescent Materials and Devices Guangdong Provincial Key Laboratory of Fiber Laser Materials and Applied TechniquesSchool of Materials Science and EngineeringSouth China University of TechnologyGuangzhouGuangdongP.R.China Guangdong Key Lab of Orthopedic Technology and Implant General Hospital of Southern Theater Command of PLAThe First School of Clinical MedicineSouthern Medical UniversityGuangzhouGuangdongP.R.China Orthopedic Centre Clinical Research CentreZhujiang HospitalSouthern Medical UniversityGuangzhouGuangdongP.R.China School of Materials Science and Engineering Zhejiang UniversityHangzhouZhejiangP.R.China Department of Chemistry&Biochemistry Stephenson Life Science Research CenterUniversity of OklahomaNormanOklahomaUSA

Sepsis,caused by uncontrollable infection and inflammatory response,leads to more than 30 million infected patients and results in high morbidity worldwide every ***,no efficient approaches have been developed for sepsis therapy due to antimicrobial resistance and inflammatory ***,we report macrophages loaded with aggregated carbon dots(ACDs)in the lysosome,termed MCDs,to treat sepsis in immunosuppressive *** ACDs are constructed by negative CDs and amine-abundant polyethyleneimine(PEI),enabling them to bear the strong antibacterial ability and enhanced photoluminescent *** ACDs are specifically located in the macrophage lysosomes,efficiently enhancing the multidrug-resistant bacteria-killing ability of *** importantly,the MCDs possess superior anti-inflammatory effects such as reducing the number of pro-inflammatory(M1)and stimulating anti-inflammatory(M2)*** effects upregulate the inflammatory cytokines(TNF-α,IL-1β,IL-4,and IL-10),ultimately resulting in increased sepsis *** work provides an intelligent approach to overcoming multidrug-resistant bacteria-induced infection from sepsis patients and paves a new avenue on employing nanoparticle-loaded cells for combating inflammation-related infection.

关键词： aggregated carbon dots in macrophages(MCDs) inflammation multidrug-resistant bacteria sepsis