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Neural Regeneration Research 2011年第31期6卷 2424-2428页

作者： Guangyao Liu Qiao Zhang Yan Jin zhongli gao Department of Orthopedics China-Japan Friendship Hospital Jifin University Changchun 130031 Jilin Province China Department of Ophthalmology Second Hospital of Jilin University Changchun 130041 Jilin Province China

The sciatic nerve is biological viscoelastic solid,with stress relaxation and creep *** this study,a comparative analysis of the stress relaxation and creep characteristics of the sciatic nerve was conducted after simulating sciatic nerve injury and anastomosing with autologous nerve or human amniotic *** results demonstrate that,at the 7 200-second time point,both stress reduction and strain increase in the human amniotic membrane anastomosis group were significantly greater than in the autologous nerve anastomosis *** findings indicate that human amniotic membrane anastomosis for sciatic nerve injury has excellent rheological characteristics and is conducive to regeneration of the injured nerve.

关键词： sciatic nerve injury anastomosis autologous nerve human amniotic membrane rheology

Stress and strain analysis on the anastomosis site sutured with either epineurial or perineurial sutures after simulation of sciatic nerve injury

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Neural Regeneration Research 2012年第29期7卷 2299-2304页

作者： Guangyao Liu Qiao Zhang Yan Jin zhongli gao Department of Orthopedics China-Japan Union Hospital Jilin University Changchun 130031 Jilin Province China Department of Ophthalmology Second Hospital Jilin University Changchun 130041 Jilin Province China

The magnitude of tensile stress and tensile strain at an anastomosis site under physiological stress is an important factor for the success of anastomosis following suturing in peripheral nerve injury treatment. Sciatic nerves from fresh adult cadavers were used to create models of sciatic nerve injury. The denervated specimens underwent epineurial and perineurial suturing. The elastic modulus （40.96 ＋ 2.59 MPa） and Poisson ratio （0.37 ＋ 0.02） of the normal sciatic nerve were measured by strain electrical measurement. A resistance strain gauge was pasted on the front, back left, and right of the edge of the anastomosis site after suturing. Strain electrical measurement results showed that the stress and strain values of the sciatic nerve following perineurial suturing were lower than those following epineurial suturing. Scanning electron microscopy revealed that the sciatic nerve fibers were disordered following epineurial compared with perineurial suturing. These results indicate that the effect of perineurial suturing in sciatic nerve injury repair is better than that of epineurial suturing.

关键词： sciatic nerve injury epineurial suture perineurial suture strain electrical measurement anastomosis site tensile stress tensile strain elastic modulus Poisson ratio biomechanics peripheral nerve injury neural regeneration

Application of Acetabular Reinforcement Ring with Hook for Correction of Segmental Acetabular Rim Defects during Total Hip Arthroplasty Revision

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Journal of Bionic Engineering 2018年第1期15卷 154-159页

作者： Jianlin Xiao Xin Zhao Yiming Wang Yuhui Yang Jianhui Zhao zhongli gao Jianlin Zuo Department of Orthopaedics China-Japan Union Hospital of Jilin University Changchun 130033 China Department of Orthopaedics The 2nd Hospital of Jilin University Changchun 13004 l China

This study investigated the biomechanical micro-motion associated with the application of acetabular reinforcement ring with hook （Ganz ring） for the correction of segmental acetabular rim defects, by finite element analysis. The objective was to determine whether the Ganz ring is suitable for correcting segmental acetabular rim defects at different regions during total hip arthroplasty revision as well as the number of screws required to fix the Ganz ring. A finite element model of the hip joint was generated to simulate and evaluate the insertion and fixation of the Ganz ring and acetabular cup in the context of segmental rim defects in the anterior column, superior portion, and posterior column. Micro-motion was the greatest in the posterior column defect and the least in the anterior column defect. However, the peak stress distribution on the remaining portion of the acetabular rim was the highest in the superior portion defect, following the pos- terior column defect and anterior column defect. Increasing the number of fixations of the Ganz ring did not decrease the micro-motion. We found that the Ganz ring effectively provided biomechanical stability during the reconstruction of the segmental rim defect as long as the screws fixed the Ganz ring well to the host bone.

关键词： segmental acetabular rim defect Ganz ring biomechanics finite element method total hip arthroplasty revision

Puerarin accelerates neural regeneration after sciatic nerve injury

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Neural Regeneration Research 2014年第6期9卷 589-593页

作者： Minfei Wu Guanjie Zhao Xiaoyu Yang Chuangang Peng Jianwu Zhao Jun Liu Rui Li zhongli gao Department of Orthopedics China-Japan Union Hospital of Jilin University Department of Nephropathy China-Japan Union Hospital of Jilin University Hand & Foot Surgery and Reparative & Reconstruction Surgery Center the Second Hospital of Jilin University

Puerarin is a natural isoflavone isolated from plants of the genus Pueraria and functions as a protector against cerebral ischemia. We hypothesized that puerarin can be involved in the repair of peripheral nerve injuries. To test this hypothesis, doses of 10, 5, or 2.5 mg/kg per day puer- arin （8-（β-D-Glucopyranosyl-7-hydroxy-3-（4-hydroxyphenyl）-4H-l-benzopyran-4-one） were injected intraperitoneally into mouse models of sciatic nerve injury. Puerarin at the middle and high doses significantly up-regulated the expression of growth-associated protein 43 in the L4_6 segments of the spinal cord from mice at 1, 2, and 4 weeks after modeling, and reduced the atro- phy of the triceps surae on the affected side and promoted the regeneration of nerve fibers of the damaged spinal cord at 8 weeks after injury. We conclude that puerarin exerts an ongoing role to activate growth-associated protein 43 in the corresponding segment of the spinal cord after sciat- ic nerve injury, thus contributing to neural regeneration after sciatic nerve injuries.

关键词： nerve regeneration peripheral nerve injury puerarin growth-associated protein 43 sci-atic nerve repair NSFC grant neural regeneration 2014-02-26

Totalhipreplacementforcongenitaldislocationofthehipinelderlypatients

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吉林大学学报(医学版) 1994年第1期 41-44页

作者： Duan Desheng Zhang Yuanying,Jiang Hongzhi,gao zhongli,Wedge J H(Department of Orthopaedic Surgery, Third Teaching Hospital)

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ＴｏｔａｌｈｉｐｒｅｐｌａｃｅｍｅｎｔｆｏｒｃｏｎｇｅｎｉｔａｌｄｉｓｌｏｃａｔｉｏｎｏｆｔｈｅｈｉｐｉｎｅｌｄｅｒｌｙｐａｔｉｅｎｔｓＤｕａｎＤｅｓｈｅｎｇ，ＺｈａｎｇＹｕａｎｙｉｎｇ，ＪｉａｎｇＨｏｎｇｚｈｉ，ＧａｏＺｈｏｎｇｌｉ，ＷｅｄｇｅＪＨ...

关键词： hip dislocation congenital/SU aged

Angle estimation of northeastern Chinese human femora in a three-dimensional Virtual environment

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Angle estimation of northeastern Chinese human femora in a t...

DISCOVERY AND DETERMINATION OF A DOMINANT MALE-STERILE GENE AND

东北三省第二届国际骨科高峰论坛暨吉林省医学会骨科学分会第十三届年会吉林省护理学会骨科护理分会第二届年会

作者： gao zhongli,Wang Jincheng,Qin Yanguo,Xiao Jianlin,Liu Tong,

Objective:To establish a method for estimating human femur morphology and angulation,and using this method to estimation angle of northeastern Chinese human femora provide useful information for assisted surgery,prosthesis design and femur ***:we chose 40 normal femora in 20 cases from lower extremities CTA DICOM data,including 10 cases of male and 10 cases of female *** ages for all the patients averaged 38.9(range,18-55).The DICOM images were imported into Mimics 10.0 software for three-dimensional reconstruction of the *** then the reconstructed 3-d models were imported into Geomagic12 software,Virtual cylinders were fitted to 4 regions of the bone painted by the user,and auto-CAD was used for measuring and calculating femoral ***- and intra-reading measurements were evaluated for this ***:Average anteversion,neckshaft and valgus angles were male 12.5°,128.5°, femalel2.7°,127.8°*** repeatability and reproducibility of the automated method showed a 5-fold reduction in inter- and intra-reading ***:provide a reliable method to estimate angles of femora.

关键词： mimics geomagic auto-CAD cylinder fitting 3d reconstruction femoral model

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Science in China,Ser.B 1982年第5期25卷 508-520页

作者：邓景扬高忠丽 Institute of Crop Breeding and Cultivation Chinese Academy of Agricultural Sciences Institute of Agricultural Sciences of Taigu County Shanxi Province China

This paper deals with the determination of one male-sterile plant found in Chinese wheatcultivar (T. aestuvum L.). It is the first time in the world that a spontaneous mutant is dis-eovered in wheat. This dominant male-sterile gene is assigned as Ta 1. This determinationfirmly confirms the existence of the genic male-sterility and provides once again the scien-tific evidence to solve the argument of this problem. On the other hand, a breeding programof using this gene, especially in recurrent selection, is herewith proposed.

关键词： DISCOVERY AND DETERMINATION OF A DOMINANT MALE-STERILE GENE AND

Studies on Single-electron Oxidation of N-Alkyl-p-Phenylenediamines and Benzidines in Aqueous Acetonitrile by Cyclovoltammetry and ESR Spectroscopy

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Chemical Research in Chinese Universities 1988年第4期 24-31页

作者： Zhang Fa, gao zhongli and Liu Youcheng(Department of Chemistry, Lanzhou University, Lanzhou)Chen Wei(Instrumental Analysis and Research Center of Lanzhou University,Lanzhou)

It is demonstrated by cyclovoltammetry and ESR spectroscopy that N,N,N,’N,’-tetramethyl; tetraethgl, tetra-n-propyl, tetra-n-butyl-p-phenylenediamine and tetraethyl, tetra-n-propyl-p-benzidine undergo deprotonat ion and two consecutive single electron transfer step CE reaction at electrode in aqueous acetonitrile with the corresponding radical cations as the intermediate. The bivalent cations produced at the electrode react not only with hydroxyl anion in the medium to give quinone but also with the N-alkyl-p-phenylene-diamines or benzidines to produce the corresponding radical cations.

关键词： Cyclovoltammetry ESR N-alkyl-p-phenylenediamine N-alkyl-p-benzidine Electron transfer

STUDIES ON NITROXIDES——KINETICS AND MECHANISM OF THE REACTION BETWEEN GLUTATHIONE AND 2,2,6,6-TETRAMETHYL-4-HYDROXYPIPERIDINE-1-OXYL RADICAL IN ALKALINE BUFFER

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Chinese Science Bulletin 1988年第24期33卷 2032-2035页

作者：刘有成高忠理 Department of Chemistry Lanzhou University

Studies on the protective action of glutathione (1) via the destruction of free radicals in biological system are of great significance. The authors have previously reported the reaction of glutathione with 2,2, 6,6-t... 详细信息

关键词： glutathione kinetics and mechanism nitroxides

CTCS3-300T车载ATP设备测试系统方案探讨

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铁路通信信号工程技术 2020年第12期17卷 25-29页

作者：高忠利北京全路通信信号研究设计院集团有限公司北京100070

探讨通过模拟车辆接口信号,利用高级修更换下来的超生命周期的设备,搭建一个可以支持系统级和单元模块级测试的简易系统。该系统充分考虑可实现性和经济性,具备上电运行、接口测试、程序读写、故障复现、备件拷机及教学培训等多种功能。

关键词： CTCS3-300T 测试系统车辆接口 300T.JCS