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China CDC weekly 2022年第30期4卷 655-659页

作者： Jiao Huang Liying Wang Chun Yu Zhaobing Liu Guanghong Yang Ziyao Lan zhongfa tao Kaike Ping He Huang Shijun Li Yan Huang Guizhou Center for Disease Control and Prevention Guiyang CityGuizhou ProvinceChina National Institute of Parasitic Diseases Chinese Center for Tropical Diseases ResearchChinese Center for Disease Control and PreventionNHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Center for Tropical DiseasesNational Center for International Research on Tropical DiseasesShanghai MunicipalityChina Doctorate School of Chemical and Biological Sciences for Health(CBS2) University of MontpellierMontpellierFrance.

Summary What is already known about this topic?Many regions in China have recently reported outbreaks of the coronavirus disease 2019(COVID-19)caused by the Omicron variant.What is added by this report?Wuchuan County,Guizhou Province reacted quickly and implemented accurate intervention measures to effectively control the outbreak.The susceptibleexposed-infectious-asymptomatic-removed(SEIAR)model was applied to evaluate the effectiveness of intervention measures.What are the implications for public health practice?Fast response measures should be taken to prevent the spread of outbreaks caused by the Omicron variant.

关键词： Guizhou measures Countermeasures

Epidemiological Characteristics of Human Brucellosis-China,2016−2019

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China CDC weekly 2021年第6期3卷 114-119,I0002,I0003页

作者： zhongfa tao Qiulan Chen Yishan Chen Yu Li Di Mu Huimin Yang Wenwu Yin Division of Infectious Disease Key Laboratory of Surveillance and Early Warning on Infectious DiseaseChinese Center for Disease Control and PreventionBeijingChina Guizhou Provincial Center for Disease Control and Prevention GuiyangGuizhouChina China Field Epidemiology Training Project BeijingChina Emory University AtlantaGAUSA

Introduction:Brucellosis is an important zoonotic infectious disease with its main mode of transmission from livestock to humans.The study analyzed epidemiological characteristics of human brucellosis from 2016 to 2019 in China,aiming to understand progress of the National Program of Brucellosis Prevention and Control.Methods:The research obtained data on human brucellosis cases reported through China’s National Notifiable Disease Reporting System(NNDRS)from January 1,2016 to December 31,2019 and described brucellosis epidemiological patterns by region,seasonality,age,sex,and occupation.Results:The number of cases reported nationwide in China decreased from 47,139(3.4/100,000)in 2016 to 37,947(2.7/100,000)in 2018,and then increased to 44,036(3.2/100,000)in 2019,with an average annual incidence of 3.0/100,000 during the four study years.Brucellosis in Xinjiang declined from 35.6/100,000 in 2016 to 16.3/100,000 in 2019-an average annual decrease of 22.9%.Brucellosis in Inner Mongolia increased from 23.8/100,000 in 2016 to 54.4/100,000 in 2019-an average increase of 31.8%per year and accounting for 22%of all reported cases.Northern China reported 95.2%of cases during this period and still had an incidence of 7.2/100,000 and 87.0%of counties being affected by brucellosis in 2019.In this region in 2019,males aged 45-64 years old had an incidence of over 15.9/100,000,compared with over 7.0/100,000 among females aged 45-64 years old.Conclusions:Although there was progress in prevention and control of human brucellosis in some provincial-level administrative divisions(PLADs)in 2016 through 2019,progress was limited nationwide and there was an overall resurgence of brucellosis in 2019.The resurgence was primarily in Inner Mongolia.An One Health approach should be strengthened to ensure successful and sustainable brucellosis prevention and control in China.

关键词： prevention nationwide occupation

Epidemiological Survey of First Human Brucellosis Outbreak Caused by the Sika Deer(Cervus nippon)—Guizhou Province,China,2019

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China CDC weekly 2021年第14期3卷 301-303页

作者： zhongfa tao Zhangping Yang Yishan Chen Shufeng Yang Jingchao Xu Yue Wang Mingyu Lei Yun Gou Qiulan Chen Yan Huang Guizhou Provincial Center for Disease Control and Prevention GuiyangGuizhouChina Division of Infectious Disease Key Laboratory of Surveillance and Early Warning on Infectious DiseaseChina Center for Disease Control and PreventionBeijingChina China Field Epidemiology Training Project BeijingChina Qiandongnan Prefecture Center for Disease Control and Prevention KailiGuizhouChina Emory University America Leishan County Center for Disease Control and Prevention LeishanGuizhouChina Qiannan Prefecture Center for Disease Control and Prevention DuyunGuizhouChina.

Summary What is already known on this topic?Brucellosis is a zoonotic infectious disease caused by Brucella spp.The main source of infection in human brucellosis is sick animals,mainly including sheep,goat,and cattle,but sika deer(Cervus nippon)can also cause human brucellosis.The first human brucellosis case in Guizhou Province was reported in 2009,and no brucellosis outbreak was reported caused by sika deer ever before.

关键词： Guizhou nippon break

Investigation of Brucellosis Caused by Raw Goat Milk—Fujian Province,China,April–June,2019

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China CDC weekly 2021年第20期3卷 430-433页

作者： Mu Di zhongfa tao Weiping Hua Jiandong Chen Jingming Cao Yanqin Deng Huihui Liu Lijie Zhang Yishan Chen Qiulan Chen Wenwu Yin Chinese Center for Disease Control and Prevention Infectious Diseases Management OfficeBeijingChina China Chinese Field Epidemiology Training Project BeijingChina Guizhou Provincial Center for Disease Control and Prevention GuiyangGuizhouChina Zhangping County Center for Disease Control ZhangpingFujianChina Fujian Provincial Center for Disease Control and Prevention FuzhouFujianChina Emory University AtlantaUSA.

Summary What is already known about this topic?Brucellosis is one of the most important zoonotic diseases in China.Goat milk and dairy products are essential pathways for foodborne transmission of brucellosis.Pasteurization can completely kill Brucella spp.in milk,and milk-borne transmission is mainly related to unhealthy dietary hygiene habits and insufficient epidemic control among animals.

关键词： China. Fujian Pasteur

2018-2022年贵州省流感样病例流行特征分析

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疾病监测 2024年第1期39卷 32-37页

作者：黄焦余春雷明玉陶忠发勾云庄丽张月黄艳贵州省疾病预防控制中心贵州贵阳550004

目的为了解2018—2022年贵州省流感样病例(ILI)的流行特征,掌握流感病毒的变异变迁情况,为科学防控流感提供依据。方法采用描述流行病学方法,对2018—2022年贵州省ILI监测数据进行分析。结果2018—2022年贵州省ILI的就诊比例(ILI%)为7.9... 详细信息

目的为了解2018—2022年贵州省流感样病例(ILI)的流行特征,掌握流感病毒的变异变迁情况,为科学防控流感提供依据。方法采用描述流行病学方法,对2018—2022年贵州省ILI监测数据进行分析。结果2018—2022年贵州省ILI的就诊比例(ILI%)为7.94%,ILI%呈逐年上升趋势。流感流行时间呈冬春季和夏秋季双峰分布。ILI%较高的前3个市(州)分别为黔南州、贵阳市和黔东南州,ILI%最低的为安顺市。5岁以下儿童ILI的占比最高,60岁及以上人群ILI占比最少,不同年龄组ILI的构成差异具有统计学意义(P<0.001)。2018—2022年贵州省ILI流感病毒核酸阳性率为11.37%,五年间不同流感病毒优势毒株交替流行。以月为单位的流感病毒核酸阳性率与ILI%呈正相关关系(P=0.028)。2018—2022年贵州省共报告流感暴发疫情227起,主要发生在中小学校,暴发疫情检出流感病毒类型主要为甲型H3N2、BV和甲型H1N1。结论2018—2022年贵州省ILI%逐年上升,2020年之后流感病毒核酸阳性率先降低后升高,流行毒株发生了改变,发病人群仍主要是学校5岁及以下儿童。需加强学校5岁以下儿童流感的健康宣教和疫苗接种。

关键词：贵州省流感样病例流感病毒暴发疫情

贵州省一起新型冠状病毒感染家庭聚集性疫情的调查分析

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医学动物防制 2024年第1期40卷 83-87页

作者：黄焦余春刘昭兵陶忠发平凯珂黄荷黄远谋秦政雷明玉黄艳贵州省疾病预防控制中心贵州贵阳550001 遵义市疾病预防控制中心务川县疾病预防控制中心

目的为了追溯2022年3月贵州省遵义市务川县报告的一起新型冠状病毒感染(Corona virus disease 2019,COVID-19,简称“新冠”)家庭聚集性疫情的感染来源和传播方式。方法本研究通过专项调查,收集此次新冠疫情感染者的基本情况、临床表... 详细信息

目的为了追溯2022年3月贵州省遵义市务川县报告的一起新型冠状病毒感染(Corona virus disease 2019,COVID-19,简称“新冠”)家庭聚集性疫情的感染来源和传播方式。方法本研究通过专项调查,收集此次新冠疫情感染者的基本情况、临床表现和诊疗情况、实验室检查、个人暴露史、密切接触史等流行病学调查资料。结果 2022年3月11日至3月17日,务川县共报告新型冠状病毒感染者12例,波及6个家庭,4例感染者(编号分别为3、4、5和9)为同一家庭(编号2)成员。首例病例(病例1)于3月7日从浙江省杭州市返回务川县,3月9日下午病例1在2号家庭居住的小区周围活动并于16:45摘下口罩吐痰。3月9日,2号家庭的孩子(代号N)于17:28踩到了病例1吐的痰液,后穿着被痰液污染的鞋子回到住处,其并未换鞋即在家里活动;3月9日晚上病例3、4、9与孩子N去鞋店买鞋,购鞋期间病例4和9反复帮N和病例3脱鞋穿鞋。测序结果显示,病例1的病毒基因序列与同时期浙江省流行的毒株完全同源,病例3、4和5的病毒基因序列与病例1的毒株序列高度同源。结论本次家庭聚集性疫情系因省外返乡的病例1随地吐痰后,2号家庭的成员N踩到痰液并机械携带引起病毒在其家人间传播导致的聚集性疫情事件。

关键词：新冠病毒感染奥密克戎聚集现场流行病学调查痰液基因序列疫情分析

Incidence and warning signs for complications of human brucellosis: a multi-center observational study from China

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Infectious Diseases of Poverty 2024年第1期13卷 53-62页

作者： Qing-Nan Shi Hui-Jie Qin Qiao-Shan Lu hu Li Zhong-Fa tao Meng-Guang Fan Mu-Heta Aishan Zeng-Qiang Kou Qiu-Lan Chen Wen-Wu Yin Yan-Ping Zhang National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases Chinese Center for Disease Control and PreventionChangbai RoadChangping DistrictBejing 102206China School of Public Health Guangxi Medical UniversityNanningChina Nanning Center for Disease Control and Prevention NanningChina Guizhou Center for Disease Control and Prevention GuiyangChina Inner Mongolia Center for Disease Control and Prevention HohhotChina Xinjiang Uighur Autonomous Region Center for Disease Control and Prevention UrumqiChina Shandong Center for Disease Control and Prevention JinanChina

Background Brucellosis is a severe zoonotic disease that is often overlooked,particularly in impoverished countries.Timely identification of focal complications in brucellosis is crucial for improving treatment outcomes.However,there is currently a lack of established indicators or biomarkers for diagnosing these complications.Therefore,this study aimed to investigate potential warning signs of focal complications in human brucellosis,with the goal of providing practical parameters for clinicians to aid in the diagnosis and management of patients.Methods A multi-center cross-sectional study was conducted in China from December 2019 to August 2021.The study aimed to investigate the clinical characteristics and complications of patients with brucellosis using a ques-tionnaire survey and medical record system.The presence of warning signs for complications was assessed using univariate and multivariate logistic regression models.Receiver operating characteristic(ROC)curves and the area under the curve(AUC)were used for variable screening and model evaluation.Results A total of 880 participants diagnosed with human brucellosis were enrolled.The median age of the patients Was 50 years[interquartile range(IQR):41.5-58.0],and 54.8%had complications.The most common organ system affected by complications was the osteoarticular system(43.1%),with peripheral arthritis(30.0%),spondylitis(16.6%),paravertebral abscess(5.0%),and sacroilitis(2.7%)being the most prevalent.Complications in other organ systems included the genitourinary system(4.7%),respiratory system(4.7%),and hematologic system(4.6%).Several fac-tors were found to be associated with focal brucellosis.These factors included a long delay in diagnosis odds ratio(OR)=3.963,95%confidence interval(CI):1.906-8.238 for>90 daysl,the presence of underlying disease(OR=1.675,95%CI:1.176-2.384),arthralgia(OR=3.197,95%CI:1.986-5.148),eye bulging pain(OR=3.482,95%CI:1.349-8.988),C-reactive protein(CRP)>10 mg/L(OR=1.910,95%CI:1.310-2.784)and erythrocyte sedimentation rate(ESR)el

关键词： Brucellosis Complications Clinical spectrum Warning signs

Complex-frequency waves:beat loss and win sensitivity

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Light(Science & Applications) 2024年第2期13卷 181-183页

作者： Qingqing Cheng tao L School of Optical-Electrical and Computer Engineering University of Shanghai for Science and TechnologyShanghai200093China Department of Respiratory Diseases and Critical Medicine Quzhou Hospital Affiliated to Wenzhou Medical UniversityQuzhou324000China National Laboratory of Solid State Microstructures College of Engineering and Applied SciencesNanjing UniversityNanjing210093China

Recent experiments have demonstrated that synthesized complex-frequency waves can impart a virtual gain to molecule sensing systems,which can effectively restore information lost due to intrinsic molecular damping.The enhancement notably amplifies the signal of trace molecular vibrational fingerprints,thereby substantially improving the upper limit of sensitivity.

关键词： thereby Complex limit

Pre-combustion mercury removal with co-production of hydrogen via coal electrolysis

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Journal of Environmental Sciences 2024年第2期136卷 382-389页

作者： Xiang Lyu Runming tao Tianyu Zhang Chemical and Biomolecular Engineering Department Ohio University165 Stocker CenterAthensOH45701USA Electrification and Energy Infrastructures Division Oak Ridge National LaboratoryOak RidgeTN37831USA Beijing Key Lab for Source Control Technology of Water Pollution College of Environmental Science and EngineeringBeijing Forestry UniversityBeijing 100083China Engineering Research Center for Water Pollution Source Control&Eco-remediation College of Environmental Science and EngineeringBeijing Forestry UniversityBeijing 100083China

Pre-combustion mercury removal via coal electrolysis was performed and investigated on a bench-scale coal electrolytic cell(CEC)systemically,and factorial design was used to determine the effect of different operating conditions(coal particle size,operating temperature,operating cell voltage,and flow rate of slurry)on the percentage of mercury removal,percentage of ash removal,and dry heating value change.The results showed that the operating cell voltage,as well as the interaction between operating cell voltage and coal particle size,are significant factors in the percentage of mercury removal.There is no significant factor in the percentage of ash removal and the dry heating value change,but the coal could be purified while keeping the dry heating value almost constant after electrolysis.A co-product of hydrogen could be produced during coal electrolysis with 50%lower energy consumption compared with water electrolysis.Meanwhile,a mechanism for mercury removal in coal was proposed.The facts indicate that coal electrolysis is a promising method for precombustion mercury removal.

关键词： Pre-combustion mercury removal Coal electrolysis Ash removal Dry heating value Hydrogen production

A Global Optimality Principle for Fully Coupled Mean-field Control Systems

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 379-413页

作者： tao HAO School of Statistics and Mathematics Shandong University of Finance and EconomicsJinan 250014China

This paper concerns a global optimality principle for fully coupled mean-field control systems.Both the first-order and the second-order variational equations are fully coupled mean-field linear FBSDEs. A new linear relation is introduced, with which we successfully decouple the fully coupled first-order variational equations. We give a new second-order expansion of Y^(ε) that can work well in mean-field framework. Based on this result, the stochastic maximum principle is proved. The comparison with the stochastic maximum principle for controlled mean-field stochastic differential equations is supplied.

关键词： optimal control global maximum principle fully coupled general mean-field FBSDE adjoint equation recursive utility