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慢性肾衰竭患者血浆sCD40和sCD40L的变化

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中华急诊医学杂志 2008年第9期17卷 969-973页

作者：姜立萍黄雯翟艳苓刘宁首都医科大学附属北京同仁医院肾内科北京100730

目的探讨慢性肾衰竭（CRF）患者血浆中可溶性CIMO（sCD40）和可溶性CD40配体（sCD40L）的变化以及在肾损伤和免疫异常中的可能作用。方法选择2006年9月至12月首都医科大学附属北京同仁医院肾内科收治的慢性肾衰竭未透析患者（CRF组）30... 详细信息

目的探讨慢性肾衰竭（CRF）患者血浆中可溶性CIMO（sCD40）和可溶性CD40配体（sCD40L）的变化以及在肾损伤和免疫异常中的可能作用。方法选择2006年9月至12月首都医科大学附属北京同仁医院肾内科收治的慢性肾衰竭未透析患者（CRF组）30例，血液透析中心维持性血液透析3个月以上的尿毒症患者（HD组）30例，与患者年龄、性别相匹配的健康正常对照组20例。采用酶联免疫吸附法（ELISA）测定血浆sCD40和sCD40L的水平，并进行相关因素分析，观察血液透析对sCD40和sCD40L的影响。用方差分析和Pearson相关性分析进行统计学分析。结果（1）CRF组和HD组sCD40水平均明显高于对照组（P〈0．01），HD组sCD40水平较CRF组升高（P〈0．01）；（2）CRF组和HD组sCD40L水平均明显高于对照组（P〈0．01），HD组sCD40L水平较CRF组轻度升高，但无显著差异（P〉0．05）；（3）CRF组sCD40水平与血肌酐（Scr）和C-反应蛋白（CRP）之间成正相关（r=0．637，P〈0．01；r=0．551，P〈0．05），sCD40L水平与Ser和CRP之间也存在相关性（r=0．553，P〈0．05；r=0．686，P〈0．01），sCD40、sCD40L水平与血压、血红蛋白（Hb）、血小板（PLT）、白细胞（WBC）、血白蛋白（AIb）、血糖（Glu）、尿素氮（Bun）及血脂等指标之间无相关性（P〉0．05）。血液透析组sCD40、sCD40L与上述指标之间无相关性，与透析病程和透析充分性（Kt／V）之间也无相关性（P〉0．05）；（4）一次血液透析过程，HD后sCD40水平较HD前略有升高，差异无统计学意义（P〉0．05），HD后sCD40L水平较HD前下降，差异具有统计学意义（P〈0．01）。结论CRF患者血浆中sCD40和sCD40L水平升高，HD患者更明显，有可能参与CRF患者肾损伤和免疫异常。

关键词：肾衰竭慢性血液透析可溶性CD40 可溶性CD40配体 CD40/CD40配体

General radiation via tunneling in Kerr and Kerr-Newman black holes

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Science china(physics,Mechanics & Astronomy) 2008年第9期51卷 1200-1205页

作者： GAO Li liu wenbiao department of physics Institute of Theoretical PhysicsBeijing Normal UniversityBeijing 100875China

Hawking radiation can be viewed as a process of quantum tunneling near the black hole horizon. When a particle with angular momentum L≠ω a tunnels across the event horizon of Kerr or Kerr-Newman black hole, the angular momentum per unit mass a should be changed. The emission rate of the massless particles under this general case is calculated, and the result is consistent with an underlying unitary theory.

关键词： Hawking radiation black hole Bekenstein-Hawking entropy quantum unitary theory Painleve coordinates

高强度运动对糖尿病心肌病大鼠心脏重塑及亚硝基-氧化还原失衡的影响

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中华物理医学与康复杂志 2024年第6期46卷 500-505页

作者：吴金涛万琼刘静康伟民郑州工业应用技术学院体育学院新郑451100 解放军总医院第三医学中心北京100039 北京朝阳中西医结合急诊抢救医院脑病医学部北京100022

目的观察高强度运动对1型糖尿病大鼠心脏重塑及亚硝基-氧化还原失衡的影响,为制订糖尿病心肌病患者运动康复处方提供理论依据及干预靶点。方法从45只8周龄健康雄性SD大鼠中取10只纳入正常对照组(NC组),剩余大鼠通过注射链脲佐菌素方式制... 详细信息

目的观察高强度运动对1型糖尿病大鼠心脏重塑及亚硝基-氧化还原失衡的影响,为制订糖尿病心肌病患者运动康复处方提供理论依据及干预靶点。方法从45只8周龄健康雄性SD大鼠中取10只纳入正常对照组(NC组),剩余大鼠通过注射链脲佐菌素方式制作1型糖尿病大鼠模型,并随机分为糖尿病对照组(DMC组)及糖尿病运动组(DME组)。NC组及DMC组大鼠均置于鼠笼内安静饲养,DME组大鼠则给予4周高强度跑台运动干预(5次/周)。于末次训练结束48 h后利用超声成像系统检测各组大鼠心脏结构及功能,采用葡萄糖氧化酶法测定空腹血糖含量;取各组大鼠心肌组织进行HE染色和天狼星红染色,经病理学观察后分析对比各组大鼠心肌细胞横断面积(CSA)及间质胶原容积分数(CVF),采用高效液相色谱法测定心肌四氢生物喋呤(BH4)含量,采用Western blot法检测心肌p47phox和p67phox、内皮型一氧化氮合酶(eNOS)、eNOS二聚体及单体蛋白表达量。结果与NC组比较,DMC组血糖、左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、心肌CSA及CVF、p47phox和p67phox蛋白表达量均显著增加(P0.05)。结论短期高强度运动能抑制糖尿病心肌病大鼠心脏重塑进程,但对大鼠体内亚硝基氧化-还原失衡无明显改善作用。

关键词：高强度运动糖尿病心肌病心脏重塑氧化应激亚硝基-氧化还原平衡

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聚合物-富勒烯太阳能电池器件物理研究进展

化学学报 2014年第2期72卷 171-184页

作者：刘震徐丰严大东北京师范大学物理学系北京100875 清华大学化学系有机光电子与分子工程教育部重点实验室北京100084

近期共轭聚合物-富勒烯太阳能电池的器件效率已突破10%并接近商业应用的标准,在科研和产业领域引起了广泛关注.伴随器件效率的提升,对有机太阳能电池器件物理过程的认识也在不断深入.本文就近年来聚合物太阳能电池的代表性工作进行综述... 详细信息

近期共轭聚合物-富勒烯太阳能电池的器件效率已突破10%并接近商业应用的标准,在科研和产业领域引起了广泛关注.伴随器件效率的提升,对有机太阳能电池器件物理过程的认识也在不断深入.本文就近年来聚合物太阳能电池的代表性工作进行综述,着重介绍提高器件效率的新方法,涵盖三相本体异质结、反向器件、等离激元共振效应和叠层器件等热点技术;并就器件工作的物理过程进行探讨,介绍热激子分离理论、非整数次电荷复合等新观点.通过材料设计、器件表征优化和理论计算等方法对聚合物太阳能电池进行的综合研究将有力推进这一新兴领域的发展和产业化.

关键词：有机太阳能电池器件物理进展聚合物-富勒烯效率

Measurement and analysis of K-shell lines of silicon ions in laser plasmas

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High Power Laser Science and Engineering 2018年第2期6卷 133-140页

作者： Bo Han Feilu Wang Jiayong zhong Guiyun Liang Huigang Wei Dawei Yuan Baojun Zhu Fang Li Chang liu Yanfei Li Jiarui Zhao Zhe Zhang Chen Wang Jun Xiong Guo Jia Neng Hua Jianqiang Zhu Yutong Li Gang Zhao Jie Zhang department of Astronomy Beijing Normal University Key Laboratory of Optical Astronomy National Astronomical Observatories Chinese Academy of Sciences IFSA Collaborative Innovation Center Shanghai Jiao Tong University National Laboratory for Condensed Matter physics Institute of Physics Chinese Academy of Sciences Research Center for Laser Fusion China Academy of Engineering Physics National Laboratory on High Power Laser and physics Chinese Academy of Sciences Key Laboratory for Laser Plasmas (MoE) and department of physics and Astronomy Shanghai Jiao Tong University

We present laboratory measurement and theoretical analysis of silicon K-shell lines in plasmas produced by Shenguang II laser facility, and discuss the application of line ratios to diagnose the electron density and temperature of laser *** types of shots were carried out to interpret silicon plasma spectra under two conditions, and the spectra from 6.6 ?A to6.85 ?A were measured. The radiative-collisional code based on the flexible atomic code(RCF) is used to identify the lines, and it also well simulates the experimental spectra. Satellite lines, which are populated by dielectron capture and large radiative decay rate, influence the spectrum profile significantly. Because of the blending of lines, the traditional G value and R value are not applicable in diagnosing electron temperature and density of plasma. We take the contribution of satellite lines into the calculation of line ratios of He-α lines, and discuss their relations with the electron temperature and density.

关键词： high energy density physics laser plasmas interaction plasmas astrophysics

Gravitational wave astronomy: the current status

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Science china(physics,Mechanics & Astronomy) 2015年第12期58卷 3-43页

作者： BLAIR David JU Li ZHAO ChunNong wen LinQing CHU Qi FANG Qi CAI RongGen GAO JiangRui LIN xueChun liu Dong WU Ling-An ZHU ZongHong REITZE David H. ARAI Koji ZHANG Fan FLAMINIO Raffaele ZHU XingJiang HOBBS George MANCHESTER Richard N. SHANNON Ryan M. BACCIGALUPI Carlo GAO Wei xu Peng BIAN Xing CAO ZhouJian CHANG ZiJing DONG Peng GONG xueFei HUANG ShuangLin JU Peng LUO ZiRen QIANG Li'E TANG wenLin WAN XiaoYun WANG Yue xu ShengNian ZANG YunLong ZHANG HaiPeng LAU Yun-Kau NI Wei-Tou School of physics The University of Western Australia State Key Laboratory of theoretical physics Institute of Theoretical Physics Chinese Academy of Sciences The School of physics & Electronic Engineering Shanxi University Laboratory of All-Solid-State Light Sources Institute of Semiconductors Chinese Academy of Science State Key Laboratroy of Modern Optical Instrumentation Department of Optical Engineering Zhejiang University Laboratory of Optical physics Institute of Physics Chinese Academy of Sciences Gravitational Wave and Cosmology Laboratory Department of Astronomy Beijing Normal University LIGO Laboratory California Institute of Technology department of physics University of Florida department of physics West Virginia University National Astronomical Observatory of Japan CSIRO Astronomy and Space Science International Centre for Radio Astronomy Research Curtin University SISSA Astrophysics Sector institute of Applied Mathematics Academy of Mathematics and Systems Science Chinese Academy of Sciences university of Chinese Academy of Sciences Morningside Center of Mathematics Chinese Academy of Sciences State Key Laboratory of Scientific and Engineering Computing Academy of Mathematics and Systems ScienceChinese Academy of Sciences department of Mathematics Henan University department of Mathematics Capital Normal University department of Geophysics College of the Geology Engineering and Geomatics Chang'an University QUEST Centre of Quantum Engineering and Space-Time Research Leibniz Universitt Hannover Max-Planck-Institut für Gravitationsphysik(Albert Einstein Institut) Aerospace Flight Dynamics Laboratory Beijing Aerospace Control Center Qian xuesen Laboratory of Launch Vehicle Technology Center for Gravitation and Cosmology Department of Physics Tsing Hua University

In the centenary year of Einstein's General Theory of Relativity, this paper reviews the current status of gravitational wave astronomy across a spectrum which stretches from attohertz to kilohertz frequencies. Sect. 1 of this paper reviews the historical development of gravitational wave astronomy from Einstein's first prediction to our current understanding the spectrum. It is shown that detection of signals in the audio frequency spectrum can be expected very soon, and that a north-south pair of next generation detectors would provide large scientific benefits. Sect. 2 reviews the theory of gravitational waves and the principles of detection using laser interferometry. The state of the art Advanced LIGO detectors are then described. These detectors have a high chance of detecting the first events in the near future. Sect. 3 reviews the KAGRA detector currently under development in Japan,which will be the first laser interferometer detector to use cryogenic test masses. Sect. 4 of this paper reviews gravitational wave detection in the nanohertz frequency band using the technique of pulsar timing. Sect. 5 reviews the status of gravitational wave detection in the attohertz frequency band, detectable in the polarisation of the cosmic microwave background, and discusses the prospects for detection of primordial waves from the big bang. The techniques described in sects. 1–5 have already placed significant limits on the strength of gravitational wave sources. Sects. 6 and 7 review ambitious plans for future space based gravitational wave detectors in the millihertz frequency band. Sect. 6 presents a roadmap for development of space based gravitational wave detectors by china while sect. 7 discusses a key enabling technology for space interferometry known as time delay interferometry.

关键词： gravitational waves ground based detectors pulsar timing spaced based detectors CMB

Terahertz metasurface zone plates with arbitrary polarizations to a fixed polarization conversion

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Opto-Electronic Science 2022年第3期1卷 9-16页

作者： Zhen Yue Jitao Li Jie Li Chenglong Zheng Jingyu liu Guocui Wang Hang xu Mingyang Chen Yating Zhang Yan Zhang Jianquan Yao Key Laboratory of Opto-Electronics Information Technology(Tianjin university) Ministry of EducationSchool of Precision Instruments and Opto-Electronics EngineeringTianjin UniversityTianjin 300072China beijing Key Laboratory for Metamaterials and Devices Department of PhysicsCapital Normal UniversityBeijing 100048China beijing Engineering Research Center for Mixed Reality and Advanced Display School of Optics and PhotonicsBeijing Institute of TechnologyBeijing 100081China department of Optoelectronic Information Science and Engineering Jiangsu UniversityZhenjiang 212013China

Metasurfaces that can realize the polarization manipulation of electromagnetic waves on the sub-wavelength scale have become an emerging research ***,a novel strategy of combining the metasurface and Fresnel zone plate to form a metasurface zone plate is proposed to realize the conversion from nearly arbitrary polarizations to a fixed ***,when one polarized wave is incident on adjacent ring zones constructed by different types of meta-atoms,the transmitted waves generated by odd-numbered and even-numbered ring zones converge at the same focus and superimpose to generate a fixed polarized *** function demonstrations,we have designed two types of metasurface zone plates:one is a focused linear polarizer,and the other can convert nearly arbitrary polarized waves into focused circularly polarized *** simulated and measured results are consistent with theoretical expectations,suggesting that the proposed concept is flexible and *** work provides an alternative platform for polarization manipulation and may vigorously promote the development of polarization photonic devices.

关键词： metasurface zone plates polarization conversion terahertz

Ferrimagnetic Properties of Bond Dilution Mixed Blume-Capel Model with Random Single-Ion Anisotropy

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Communications in theoretical physics 2005年第4X期44卷 743-748页

作者： liu Lei YAN Shi-Lei department of physics Suzhou University Suzhou 215006 China Jiangsu Key Loboratory of Thin Films Suzhou University Suzhou 215006 China CCAST (World Loboratory) P.O. Box 8730 Beijing 100080 China

We study the ferrimagnetic properties of spin 1/2 and spin-1 systems by means of the effective field theory. The system is considered in the framework of bond dilution mixed Blume-Capel mode/ （BCM） with random single-ion anisotropy. The investigation of phase diagrams and magnetization curves indicates the existence of induced magnetic ordering and single or multi-compensation points. Special emphasis is placed on the influence of bond dilution and random single-ion anisotropy on normal or induced magnetic ordering states and single or multi-compensation points. normal magnetic ordering states take on new phase diagrams with increasing randomness （bond and anisotropy）, while anisotropy induced magnetic ordering states are always occurrence no matter whether concentration of anisotropy is large or small. Existence and disappearance of compensation points rely strongly on bond dilution and random singleion anisotropy. Some results have not been revealed in previous papers and predicted by Néel theory of ferrimagnetism.

关键词： ferrimagnetic property mixed Blume-Capel model induced magnetic ordering compensation point bond dilution and random single-ion anisotropy

The next detectors for gravitational wave astronomy

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Science china(physics,Mechanics & Astronomy) 2015年第12期58卷 91-124页

作者： BLAIR David JU Li ZHAO ChunNong wen LinQing MIAO HaiXing CAI RongGen GAO JiangRui LIN xueChun liu Dong WU Ling-An ZHU ZongHong HAMMOND Giles PAIK Ho Jung FAFONE Viviana ROCCHI Alessio BLAIR Carl MA YiQiu QIN JiaYi PAGE Michael School of physics The University of Western Australia School of physics and Astronomy University of Birmingham State Key Laboratory of theoretical physics Institute of Theoretical Physics Chinese Academy of Sciences The School of physics & Electronic Engineering Shanxi University Laboratory of All-Solid-State Light Sources Institute of Semiconductors Chinese Academy of Science State Key Laboratroy of Modern Optical Instrumentation Department of Optical Engineering Zhejiang University Laboratory of Optical physics Institute of Physics Chinese Academy of Sciences Gravitational Wave and Cosmology Laboratory Department of Astronomy Beijing Normal University School of physics and Astronomy SUPA University of Glasgow department of physics University of Maryland College Park university of Rome Tor Vergata INFN Roma Tor Vergata

This paper focuses on the next detectors for gravitational wave astronomy which will be required after the current ground based detectors have completed their initial observations, and probably achieved the first direct detection of gravitational waves. The next detectors will need to have greater sensitivity, while also enabling the world array of detectors to have improved angular resolution to allow localisation of signal sources. Sect. 1 of this paper begins by reviewing proposals for the next ground based detectors,and presents an analysis of the sensitivity of an 8 km armlength detector, which is proposed as a safe and cost-effective means to attain a 4-fold improvement in sensitivity. The scientific benefits of creating a pair of such detectors in china and Australia is emphasised. Sect. 2 of this paper discusses the high performance suspension systems for test masses that will be an essential component for future detectors, while sect. 3 discusses solutions to the problem of Newtonian noise which arise from fluctuations in gravity gradient forces acting on test masses. Such gravitational perturbations cannot be shielded, and set limits to low frequency sensitivity unless measured and suppressed. Sects. 4 and 5 address critical operational technologies that will be ongoing issues in future detectors. Sect. 4 addresses the design of thermal compensation systems needed in all high optical power interferometers operating at room temperature. Parametric instability control is addressed in sect. 5. Only recently proven to occur in Advanced LIGO, parametric instability phenomenon brings both risks and opportunities for future detectors. The path to future enhancements of detectors will come from quantum measurement technologies. Sect. 6 focuses on the use of optomechanical devices for obtaining enhanced sensitivity, while sect. 7 reviews a range of quantum measurement options.

关键词： future gravitational wave detectors opto-mechanics quantum limit