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Generation of Entangled Displacement Fock State of Trapped Ion Manipulated by a Laser Beam

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Communications in Theoretical Physics 2008年第5期49卷 1315-1318页

作者： WANG zhong-jie zhang Ke-Fu Department of Physics Anhui Normal University Wuhu 241000 China

The interaction of a single two-level two-mode trapped ion with a laser beam has been studied theoretically. With application of a unitary transformation, an analytical solution to this quantum system has been obtained without performing the Lamb-Dicke approximation. In this system the entangled displacement Fock state is produced.

关键词： trapped ion unitary transformation Lamb-Dicke limit

Synthesis and Crystal Structure of 2-tert-Butyl-5-(4-tert-butylbenzylthio)-4-chloropyridazin-3(2H)-one

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Chemical Research in Chinese Universities 2006年第6期22卷 763-764页

作者： XU Liang-zhong YU Guan-ping XU zhong-jie zhang Gong-sheng ZHAI Zhi-wei College of Chemistry and Molecular Engineering Qingdao University of Science and Technology Qingdao 266042 P. R. China

The title compound, 2-ten-butyl-6 （4-ten -butylbenzylthio） -4-chloropyridazin-3 （ 2H ） -one, was synthesized from 1 -ten-butylhydrazine, （ Z ） -2,3 -dichloro-3 -formylacrylic acid and （ 4 -tert -butylphenyl ） methanethiol in several steps. It crystallized in an orthorhombic space group Pnma with Mr = 364. 93 （ C19H25 ClN2OS）, a = 1. 0091 （2） nm, b = 0.7076（2） nm, c=2. 8103（5） nm, V=2.0066（6） nm^3, Z=4, Dc =1. 192 g/cm^3, F（000） =765, μ=0.301 mm , final R1 = 0. 0665, and wR = 0. 1913 for 1927 unique reflections. Inter- and intramolecular hydrogen bond C-H…O interactions stabilize the structure.

关键词： Pyridaben Synthesis Crystal structure

Synthesis,Characterization and Biological Activities of Novel Acrylamide Compounds

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Chemical Research in Chinese Universities 2008年第5期24卷 575-578页

作者： XU Liang-zhong XU zhong-jie zhang Gong-sheng ZHOU Kai ZHAI Zhi-wei College of Chemistry and Molecule Engineering Qingdao University of Science and Technology Qingdao 266042 P. R. China

With dimethomorph and flumorph as the leading compounds, four novel acrylamide compounds with two types of structure were designed and synthesized by means of the method of ＂me too chemistry＂. The target compounds were characterized by 1H NMR, IR, MS, and elemental analysis. The influences of solvent and raw material on the yield were investigated and optimum processing conditions were determined. The results of preliminary biological tests show that all those compounds exhibit certain antifungal activities.

关键词： Acrylamide derivatives Biological activity Process optimum

The receptor tyrosine kinase torso regulates ecdysone homeostasis to control developmental tinning in Bombyx mori

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Insect Science 2021年第6期28卷 1582-1590页

作者： zhong-jie zhang Xiao-Jing Liu Ye Yu Fang-Ying Yang Kai Li School of Life Science East China Normal UniversityShanghai 200062China Key Laboratory of Insect Developmental and Evolution-ary Biology Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijing 100049China

Insect growth and development are precisely controlled by hormone *** prothoracicotropic hormone(PTTH)receptor,Torso,is a member of the receptor tyrosine kinase family in *** of Torso by PTTH triggers biosynthesis and release of the steroid hormone in the prothoracic gland(PG).Although numbers of genes functioning in steroid hormone synthesis and metabolism have been identified in insects,the PTTH transduction pathway via its receptor Torso is poorly *** the current study,we describe a loss-of-function analysis of Torso in the silkworm,Bombyx mori,by targeted gene disruption using the transgenic CRISPR/Cas9(clustered regularly interspaced short palindromic repeats/RNA-guided Cas9 nucleases)*** of *** Torso(BmTorso)did not eventually affect larval ecdysis and metamorphosis ***,BmTorso deficiency resulted in significant extension of developing time during larval and pupal stages with increased pupa and cocoon *** eedysteriod titers in the hemolymph of BmTorso mutants sharpy *** levels of genes involved in ecdysone biosynthesis and eedysteroid signaling pathways were significantly reduced in BniTorso-defic'iQnt ***,RNA-Seq analysis revealed that genes involved in the longevity pathway and protein processing in the endoplasmic reticulum pathway were affected after BmTorso *** results indicate that Torso is critical for maintaining steroid hormone homeostasis in insects.

关键词： Bombyx mori CRISPR/Cas9 developmental timing Torso

Positive periodic solutions of higher-dimensional nonlinear functional difference equations

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Journal of Central South University of Technology 2005年第z1期12卷 274-277页

作者： DAI Bin-xiang ZOU jie-zhong zhang Na School of Mathematical Science and Computing Technology Central South University Changsha 410075 China School of Mathematical Science and Computing Technology Central South University Changsha 410075 China College of Mathematics and Econometrics Hunan University Changsha 410082 China

In this paper, we apply a cone theoretic fixed point theorem to obtain sufficient conditions for the existence of multiple positive periodic solutions to the higher-dimensional functional difference equations of the f... 详细信息

关键词： positive periodic solution difference equations cone fixed point theorem

BmHpo mutation induces smaller body size and late stage larval lethality in the silkworm,Bombyx mori

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Insect Science 2018年第6期25卷 1006-1016页

作者： Xia Xu Hong-Lun Bi zhong-jie zhang Yang Yang Kai Li Yong-Ping Huang Yong zhang Lin He School of Life Science East China Normal UniversityShanghaiChina Key Laboratory of Insect Developmental and Evolutionary Biology Institute of Plant Physiology and EcologyShanghai Institutes for Biological SciencesChinese Academy of SciencesShanghaiChina

As a core member of the Hippo signaling pathway,Hpo plays a critical role in regulating growth and *** studies reported that loss of function of Hpo results in increased proliferation,reduced apoptosis and induction of tissue overgrowth in *** this study,we used CRISPR/Cas9(Clustered Regularly Interspaced Short Palindromic Repeats/Casg)to study Hpo gene (BmHpo)function in the lepidopteran insect Bombyx mori,known commonly as the *** analysis of BmHpo revealed an array of deletions in *** found that BmHpo knockout resulted in defects in body size regnlation,in developmental defects and pigment accumulation and early death. Our data show that BmHpo is essential for regulation of insect growth and development and that CRISPR/Cas9technology can serve as a basis for functional analysis of target genes in lepidopteran insects.

关键词： Bombyx mori CRISPR/Cas9 developmental defects Hippo signaling path- way Hpo

Novel high- with low specific on-resistance high voltage lateral double-diffused MOSFET

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Chinese Physics B 2017年第2期26卷 382-386页

作者： Li-Juan Wu zhong-jie zhang Yue Song Hang Yang Li-Min Hu Na Yuan School of Physics ＆ Electronic Science Changsha University of Science ＆ Technology Changsha 410114 China

A novel voltage-withstand substrate with high-K（HK, k 〉 3.9, k is the relative permittivity） dielectric and low specific on-resistance（Ron,sp） bulk-silicon, high-voltage LDMOS（HKLR LDMOS）is proposed in this paper. The high-K dielectric and highly doped interface N＋-layer are made in bulk silicon to reduce the surface field drift region. The high-K dielectric can fully assist in depleting the drift region to increase the drift doping concentration（Nd） and reshape the electric field distribution. The highly doped N＋-layer under the high-K dielectric acts as a low resistance path to reduce the Ron,sp. The new device with the high breakdown voltage（BV）, the low Ron,sp, and the excellent figure of merit（FOM = BV^2/Ron,sp） is obtained. The BV of HKLR LDMOS is 534 V, Ron,sp is 70.6 m？·cm^2, and FOM is 4.039 MW·cm^（-2）.

关键词： LDMOS high-K dielectric highly doped N+-layer high voltage specific on-resistance

A palmitoyltransferase Approximated gene Bm-app regulates wing development in Bombyx mori

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Insect Science 2020年第1期27卷 2-13页

作者： Ye Yu Xiao-Jing Liu Xiao Ma zhong-jie zhang Tai-Chu Wang Fan Sun Cheng-Xiang Hou Mu-Wang Li School of Biotechnology Jiangsu University of Science and TechnologyZhenjiangJiangsuChina Sericultural Research Institute Chinese Academy of Agricultural SciencesZhenjiangJiangsuChina Sericultural Research Institute Anhui Academy of Agricultural SciencesHefeiChina

The silkworm Bombyx mori is an important lepidopteran model insect in which many kinds of natural mutants have been ***,molecular mechanisms of most of these mutants remain to be *** we report the identification of a gene Bm-app is responsible for the silkworm minute wing(mw)mutation which exhibits exceedingly small wings during pupal and adult *** with the wild type silkworm,relative messenger RNA expression of Bm-app is significantly decreased in the ul 1 mutant strain which shows mw phenotype.A 10 bp insertion in the putative promoter region of the Bm-app gene in mw mutant strain was identified and the dual luciferase assay revealed that this insertion decreased Bm-app promoter ***,clustered regularly interspaced short palindromic repeats/RNA-guided Cas9 nucleases-mediated depletion of the Bm-app induced similar wing defects which appeared in the mw mutant,demonstrating that Bm-app controls wing development in ***-app encodes a palmitoyltransferase and is responsible for the palmitoylation of selected cytoplasmic proteins,indicating that it is required for cell mitosis and growth during wing *** also discuss the possibility that Bm-app regulates wing development through the Hippo signaling pathway in ***.

关键词： Bombyx mori CRISPR/Cas9 minute wing palmitoyltransferase promoter

The relationship between single nucleotide polymorphisms in estrogenmetabolizing genes CYP1A1,CYP17,COMT and estrogen receptor alpha and the risk of endometrial adenocarcinoma among the Chinese women

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现代妇产科进展 2007年第1期16卷 76-80页

作者： Yang Xingsheng Liu jie zhong Yanhui zhang Xian Wang Yan Department of Gynecology and Obstetrics Qilu Hospital of Shandong University Jinan 250012

Objective:To explore whether polymorphisms of the genes responsible for catechol estrogen(CE)formation via estrogen biosynthesis(CYP17)and hydroxylation (CYP1A1)and CE inactivation(COMT)and ERa are associated with an elevated risk for en- dometrial adenocarcinoma in Chinese ***:A multigenic case-control study was conducted,eighty-seven endometrial adenocarcinoma patients and ninety controls were recrui- ***-RFLP assays were used to determine the genotypes of estrogen-metabolizing genes and ERa ***:The endometrial adenocarcinoma risk associated with individual susceptibili- ty genotypes varied among the six polymorphic sites and was the highest for CYP17,followed by CYP1 A1 Ile-Val,CYP1A1 MspI,COMT,ERa XhaI and ERa *** logistic regres- sion showed the CYP1A1 MspI genotype was the most significant determinant for endometrial adenocarcinoma development and was associated with a 3.61 fold increase in risk(95% confi- dence interval,1.73～7.55).Furthermore,a trend of increasing risk for developing endometrial adenocarcinoma was found in women harboring higher numbers of high-risk ***- sion:The CYP1A1,CYP17 and ERa XbaI genotypes are related to the susceptibility of endome- trial adenocarcinoma,they may be useful markers for predicting endometrial adenocarcinoma *** allele encoding for low acticity COMT,ERa PvuII may not be a genetic risk factor for endometrial adenocarcinoma.

关键词：子宫内膜肿瘤基因治疗方法护理措施