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Fast topological pumping for the generation of large-scale Greenberger–Horne–Zeilinger states in a superconducting circuit

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Frontiers of physics 2022年第6期17卷 143-161页

作者： Jin-Xuan Han Jin-Lei Wu zhong-hui yuan Yan Xia Yong-yuan Jiang Jie Song School of Physics Harbin Institute of TechnologyHarbin 150001China Department of Optoelectronics Science Harbin Institute of TechnologyWeihai 264209China Department of Physics Fuzhou UniversityFuzhou 350002China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China Key Laboratory of Micro-Nano Optoelectronic Information System Ministry of Industry and Information TechnologyHarbin 150001China Key Laboratory of Micro-Optics and Photonic Technology of Heilongjiang Province Harbin Institute of TechnologyHarbin 150001China

Topological pumping of edge states in the finite lattice with nontrivial topological phases provides a powerful means for robust excitation transfer,requiring extremely slow evolution to follow an adiabatic ***,we propose fast topological pumping via edge channels to generate large-scale Greenberger–Horne–Zeilinger(GHZ)states in a topological superconducting circuit with a sped-up evolution *** scheme indicates a conceptual way of designing fast topological pumping related to the instantaneous energy spectrum characteristics rather than relying on the shortcuts to *** on fast topological pumping,large-scale GHZ states show greater robustness against on-site potential defects,the fluctuation of couplings and losses of the system in comparison with the conventional adiabatic topological *** experimentally feasible qutrit-resonator coupling strengths and moderate decay rates of qutrits and resonators,fast topological pumping drastically improves the scalability of GHZ states with a high *** work opens up prospects for the realization of large-scale GHZ states based on fast topological pumping in the superconducting quantum circuit system,which provides potential applications of topological matters in quantum information processing.

关键词： topological pumping superconducting ciruit large-scale Greenberger-Horne-Zeilinger states

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Effect of high glucose levels on the calcification of vascular smooth muscle cells by inducing osteoblastic differentiation and intracellular calcium deposition via BMP-2/Cbfα-1 pathway

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第12期11卷 905-911页

作者： Fang LIU hui zhong Jing-yuan LIANG Ping FU Zhi-juan LUO Li ZHOU Rong GOU Jun HUANG Division of Nephrology West China Hospital Sichuan University Chengdu 610041 China

In this paper, we investigate the effect and the possible mechanism of high glucose levels on the calcification of human aortic smooth muscle cells （HASMCs）. HASMCs were divided into four groups： normal glucose group （NG）, osmolality control group （OC）, high glucose group （HG, HASMCs culture medium containing 30 mmol/L glucose）, and high glucose plus recombinant human Noggin protein （bone morphogenetic protein-2 （BMP-2） antagonist） group （HN）. The mRNA levels and the protein expressions of BMP-2 and core binding factor alpha-1 （Cbfa-1） were measured by real-time quantitative polymerase chain reaction （PCR） and Western blot. After induced by 10 mmol/L β-glycerol phosphoric acid, cells were had＇vested for assessments of alkaline phosphatase （ALP） activities at Days 1,2, and 3, and intracellular calcium contents at Days 7 and 14, respectively. High glucose levels increased the mRNA levels and the protein expressions of BMP-2 and Cbfa-1 （P〈0.05）. The expression of Cbfa-1 was partially blocked by Noggin protein （P〈0.05）, while BMP-2 was not （P〉0.05）. After being induced by β-glycerol phosphoric acid, high glucose levels increased the ALP activity [（48.63±1.03） vs. （41.42±2.28） U/mg protein, Day 3; P〈0.05] and the intracellular calcium content [（2.76±0.09） vs. （1.75±0.07） μmol/mg protein, Day 14; P〈0.05] in a time-dependent manner when compared with the NG group, while the ALP activity could not be blocked by Noggin protein [（48.63±1.03） vs. （47.37±0.97） U/mg protein, Day 3; P〉0.05]. These results show that high glucose levels can evoke the calcification of HASMCs by inducing osteoblastic trans-differentiation and intracellular calcium deposition via the BMP-2/Cbfa-1 pathway, which can be partially blocked by Noggin protein.

关键词： Bone morphogenetic protein (BMP) Core binding factor alpha-1 (Cbfa-1) Vascular smooth muscle cell,Noggin protein

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脉冲电沉积纳米晶Ni-Co合金镀层热稳定性的研究

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材料工程 2009年第4期37卷 52-56页

作者：钟远辉戴品强戴春福福州大学材料科学与工程学院福州350108

采用X射线衍射（XRD）、能谱分析（EDS）等方法研究脉冲电沉积法制备的纳米晶Ni-Co合金镀层的组织结构和合金成分。测定不同退火温度下纳米晶Ni-Co合金镀层的显微硬度,并着重研究Ni-23.5%Co（质量分数）合金的热稳定性,结果表明：随着... 详细信息

采用X射线衍射（XRD）、能谱分析（EDS）等方法研究脉冲电沉积法制备的纳米晶Ni-Co合金镀层的组织结构和合金成分。测定不同退火温度下纳米晶Ni-Co合金镀层的显微硬度,并着重研究Ni-23.5%Co（质量分数）合金的热稳定性,结果表明：随着退火温度的升高,纳米晶Ni-Co合金在低温退火后显微硬度有所升高,在250℃时达到最高值,然后随退火温度的继续升高而降低。纳米晶Ni-23.5%Co合金镀层的晶粒尺寸逐渐增大,从原始晶粒尺寸13.5nm长大到300℃时的98.5nm,在升温速率为***-1的DSC曲线中,Ni-23.5%Co合金在约300-350℃一直是低能放热,随后出现明显的放热峰,其峰值温度为372℃,放热焓为14.22J·g^-1。通过测定不同升温速率条件下的DSC曲线峰值温度,由Kissinger方程求得纳米晶Ni-23.5%Co合金镀层的晶粒长大激活能为212.5kJ/mol。

关键词：脉冲电沉积 Ni-Co合金镀层热稳定性激活能

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Inverse Learning Control of Nonlinear Systems Using Support Vector Machines

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Journal of Shanghai Jiaotong university(Science) 2005年第2期10卷 135-138,142页

作者：胡中辉李远贵蔡云泽许晓鸣 Dept. of Automation Shanghai Jiaotong Univ. Shanghai 200030 China

An inverse learning control scheme using the support vector machine (SVM) for regression was proposed. The inverse learning approach is originally researched in the neural networks. Compared with neural networks, SVMs overcome the problems of local minimum and curse of dimensionality. Additionally, the good generalization performance of SVMs increases the robustness of control system. The method of designing SVM inverse learning controller was presented. The proposed method is demonstrated on tracking problems and the performance is satisfactory.

关键词： support vector machines learning control inverse model nonlinear system

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浅谈省道S225线改建工程施工监理

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山西建筑 2007年第10期33卷 334-335页

作者：钟元辉兴宁市公路局

针对省道S225线合水至黄槐段公路改建工程,探讨了公路改建工程施工监理的特殊性,总结、积累了公路改建施工监理的一些做法及管理经验,供类似工程参考借鉴。

关键词：公路工程工程质量管理配合比设计拌合设备监理

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Dynamic Regulation of Hydrogen Bonding Networks and Solvation Structures for Synergistic Solar‑Thermal Desalination of Seawater and Catalytic Degradation of Organic Pollutants

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Nano-Micro Letters 2025年第2期17卷 548-565页

作者： Ming‑yuan Yu Jing Wu Guang Yin Fan‑Zhen Jiao zhong‑Zhen Yu Jin Qu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Although solar steam generation strategy is efficient in desalinating seawater,it is still challenging to achieve continuous solar-thermal desalination of seawater and catalytic degradation of organic ***,dynamic regulations of hydrogen bonding networks and solvation structures are realized by designing an asymmetric bilayer membrane consisting of a bacterial cellulose/carbon nanotube/Co_(2)(OH)_(2)CO_(3)nanorod top layer and a bacterial cellulose/Co_(2)(OH)_(2)CO_(3)nanorod(BCH)bottom ***,the hydrogen bonding networks inside the membrane can be tuned by the rich surface–OH groups of the bacterial cellulose and Co_(2)(OH)_(2)CO_(3)as well as the ions and radicals in situ generated during the catalysis ***,both SO_(4)^(2−)and HSO_(5)−can regulate the solvation structure of Na^(+)and be adsorbed more preferentially on the evaporation surface than Cl^(−),thus hindering the de-solvation of the solvated Na^(+)and subsequent nucleation/growth of ***,the heat generated by the solar-thermal energy conversion can accelerate the reaction kinetics and enhance the catalytic degradation *** work provides a flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane for synergistic solar thermal desalination of seawater/brine and catalytic degradation of organic pollutants.

关键词： Solar steam generation Seawater desalination Catalytic degradation Bacterial cellulose Cobalt hydroxycarbonate nanorods

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肝硬化合并结核性腹膜炎临床特点(附32例临床分析)

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航空航天医药 2010年第1期21卷 18-19页

作者：戴小灵钟远辉广东省梅州市人民医院感染科广东梅州514000

目的：分析肝硬化合并结核性腹膜炎（TBP）的临床特点，以期减少误诊率漏诊率及提高治疗疗效。方法：将我院从2000—01～2009—04收治32例确诊为肝硬化合并TBP的临床表现、实验室检查及治疗、预后情况进行回顾性分析。结果：肝硬化合并... 详细信息

目的：分析肝硬化合并结核性腹膜炎（TBP）的临床特点，以期减少误诊率漏诊率及提高治疗疗效。方法：将我院从2000—01～2009—04收治32例确诊为肝硬化合并TBP的临床表现、实验室检查及治疗、预后情况进行回顾性分析。结果：肝硬化合并TBP临床表现不典型，实验检测阳性率低，极易误诊，其中首诊误诊为原发性腹膜炎81．3％。疗效均满意。结论：肝硬化合并TBP确诊困难，需综合考虑、全面分析，肝肾功能者正常者在保肝基础上采用LFHSE（左氧氟沙星异烟肼链霉素乙胺丁醇）方案安全有效，肝功能异常者则采用LFSE方案，联用胸腺肽α1及腹腔灌洗注射异烟肼、地塞米松综合性治疗可明显提高疗效。

关键词：肝硬化:结核性腹膜炎

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认知行为疗法对精神分裂症患者康复效果分析

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深圳中西医结合杂志 2016年第19期26卷 82-84页

作者：林伟泉钟远惠广州市民政局精神病院广东广州510430

目的:分析通过认知行为疗法治疗精神分裂症的康复效果。方法:将2012年2月至2013年3月广州市民政局精神病院收治的60例精神分裂症患者随机分组为对照组与观察组,各30例,对照组患者给予常规的抗精神病药物治疗,观察组患者在对照组的基础... 详细信息

目的:分析通过认知行为疗法治疗精神分裂症的康复效果。方法:将2012年2月至2013年3月广州市民政局精神病院收治的60例精神分裂症患者随机分组为对照组与观察组,各30例,对照组患者给予常规的抗精神病药物治疗,观察组患者在对照组的基础上采取认知行为疗法方案进行干预,观察两组患者治疗前后的生活质量情况及认知能力评分。结果:观察组生活质量及认知能力评分明显优于对照组,组间比较,差异具有统计学意义(P<0.05)。结论:对精神分裂症患者在常规抗精神药物治疗的基础上采取认知行为疗法进行干预,可有效改善患者的认知功能及生活质量,其效果显著。

关键词：认知行为疗法精神分裂症抗精神病疗法

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多孔载药n-HA/PEEK/CS复合材料的制备与性能

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功能高分子学报 2018年第3期31卷 267-272页

作者：周浩浩曹慧群周莉罗仲宽胡惠媛黄丹榕深圳大学化学与环境工程学院广东深圳518060

首先以纳米羟基磷灰石(n-HA)、聚醚醚酮(PEEK)、壳聚糖(CS)为原材料进行复合,制得n-HA/PEEK/CS复合材料;然后采用聚乙烯吡咯烷酮(PVP)/NaCl作为致孔剂对复合材料进行致孔,载入抗生素类药物红霉素(EM),制备出一种新型多孔载药复合骨修复... 详细信息

首先以纳米羟基磷灰石(n-HA)、聚醚醚酮(PEEK)、壳聚糖(CS)为原材料进行复合,制得n-HA/PEEK/CS复合材料;然后采用聚乙烯吡咯烷酮(PVP)/NaCl作为致孔剂对复合材料进行致孔,载入抗生素类药物红霉素(EM),制备出一种新型多孔载药复合骨修复材料n-HA/PEEK/CS/EM。通过傅里叶红外光谱(FT-IR)、扫描电镜(SEM)、力学测试、紫外-可见分光光度计(UVVis)表征了该复合材料的形貌结构、力学性能及药物缓释性能。结果表明:当m(PVP)∶m(NaCl)=1∶6时,可以得到孔隙率为51.6%、抗压强度为6.98MPa的n-HA/PEEK/CS/EM复合材料;当CS的质量分数由0增加到30%时,最大药物释放质量浓度由39.8μg/mL增加到52.0μg/mL;药物载入后无新化学键生成;材料形成了三维立体多孔结构,孔径为5~50μm,有利于营养物质的运输及细胞、组织的长入。

关键词：骨材料聚醚醚酮壳聚糖纳米羟基磷灰石释药性

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Poorly controlled type II diabetes mellitus significantly enhances postoperative chemoresistance in patients with stage III colon cancer

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World Journal of Gastroenterology 2025年第3期31卷 29-41页

作者： Ruo-Yu Guan Jia-Wei Wu Zi-Yun yuan Zhi-yuan Liu Zi-Zhu Liu Zhi-Cong Xiao Jing-hui Li Cheng-Zhi Huang Jun-Jiang Wang Xue-Qing Yao Guangdong Cardiovascular Institute Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesSouthern Medical UniversityGuangzhou 510080Guangdong ProvinceChina Department of Gastrointestinal Surgery Department of General SurgeryGuangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080Guangdong ProvinceChina Department of General Surgery Guangdong Provincial People’s Hospital Ganzhou Hospital(Ganzhou Municipal Hospital)Ganzhou 341000Jiangxi ProvinceChina Shantou University Medical College Shantou 515041Guangdong ProvinceChina School of Medicine South China University of TechnologyGuangzhou 510006Guangdong ProvinceChina Gannan Medical University Ganzhou 341000Jiangxi ProvinceChina

BACKGROUND Type II diabetes mellitus(T2DM)has been associated with increased risk of colon cancer(CC)and worse prognosis in patients with *** effects of T2DM on postoperative chemoresistance rate(CRR)and long-term disease-free survival(DFS)and overall survival(OS)in patients with stage III CC who receive curative resection remain *** To investigate whether T2DM or glycemic control is associated with worse postoperative survival outcomes in stage III *** This retrospective cohort study included 278 patients aged 40-75 years who underwent surgery for stage III CC from 2018 to *** on preoperative T2DM history,the patients were categorized into non-DM(n=160)and DM groups(n=118).The latter was further divided into well-controlled(n=73)and poorly controlled(n=45)groups depending on the status of glycemic ***,OS,and CRR were compared between the groups and Cox regression analysis was used to identify risk *** Patients in the DM and non-DM groups demonstrated similar DFS,OS,and CRR(DFS:72.03%vs 78.75%,P=0.178;OS:81.36%vs 83.12%,P=0.638;CRR:14.41%vs 7.5%,P=0.063).Poorly controlled DM was associated with a significantly worse prognosis and higher CRR than well-controlled DM(DFS:62.22%vs 78.07%,P=0.021;OS:71.11%vs 87.67%,P=0.011;CRR:24.40%vs 8.22%,P=0.015).High preoperative fasting plasma glucose[DFS:Hazard ratio(HR)=2.684,P<0.001;OS:HR=2.105,P=0.019;CRR:HR=2.214,P=0.005]and glycosylated hemoglobin levels(DFS:HR=2.344,P=0.006;OS:HR=2.119,P=0.021;CRR:HR=2.449,P=0.009)indicated significantly poor prognosis and high CRR,while T2DM history did not(DFS:HR=1.178,P=0.327;OS:HR=0.933,P=0.739;CRR:HR=0.997,P=0.581).CONCLUSION Increased preoperative fasting plasma glucose and glycosylated hemoglobin levels,but not T2DM history,were identified as risk factors associated with poor postoperative outcomes and high CRR in patients with stage III CC.

关键词： Colon cancer Chemoresistance Diabetes mellitus Prognosis Type II diabetes mellitus

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