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Functional near-infrared spectroscopy in non-invasive neuromodulation

Neural Regeneration Research 2024年第7期19卷 1517-1522页

作者： Congcong huo Gongcheng Xu Hui Xie Tiandi Chen Guangjian Shao Jue Wang Wenhao Li Daifa Wang Zengyong Li Beijing Advanced Innovation Center for Biomedical Engineering Key Laboratory for Biomechanics and Mechanobiology of Ministry of EducationSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Beijing Key Laboratory of Rehabilitation Technical Aids for Old-Age Disability National Research Center for Rehabilitation Technical AidsBeijingChina School of Mechatronic Engineering and Automation Foshan UniversityFoshanGuangdong ProvinceChina School of Rehabilitation Engineering Beijing College of Social AdministrationBeijingChina Key Laboratory of Neuro-functional Information and Rehabilitation Engineering of the Ministry of Civil Affairs BeijingChina

Non-invasive cerebral neuromodulation technologies are essential for the reorganization of cerebral neural networks,which have been widely applied in the field of central neurological diseases,such as stroke,Parkinson’s disease,and mental *** significant advances have been made in neuromodulation technologies,the identification of optimal neurostimulation paramete rs including the co rtical target,duration,and inhibition or excitation pattern is still limited due to the lack of guidance for neural *** r,the neural mechanism unde rlying neuromodulation for improved behavioral performance remains poorly ***,advancements in neuroimaging have provided insight into neuromodulation *** near-infrared spectroscopy,as a novel non-invasive optical brain imaging method,can detect brain activity by measuring cerebral hemodynamics with the advantages of portability,high motion tole rance,and anti-electromagnetic *** functional near-infra red spectroscopy with neuromodulation technologies offe rs an opportunity to monitor the cortical response,provide realtime feedbac k,and establish a closed-loop strategy integrating evaluation,feedbac k,and intervention for neurostimulation,which provides a theoretical basis for development of individualized precise neuro *** aimed to summarize the advantages of functional near-infra red spectroscopy and provide an ove rview of the current research on functional near-infrared spectroscopy in transcranial magnetic stimulation,transcranial electrical stimulation,neurofeedback,and braincomputer ***,the future perspectives and directions for the application of functional near-infrared spectroscopy in neuromodulation are *** conclusion,functional near-infrared spectroscopy combined with neuromodulation may promote the optimization of central pellral reorganization to achieve better functional recovery form central nervous system

关键词： brain-computer interface cerebral neural networks functional near-infrared spectroscopy neural circuit neurofeedback neurological diseases neuromodulation non-invasive brain stimulation transcranial electrical stimulation transcranial electrical stimulation

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Artificial Intelligence Meets Flexible Sensors:Emerging Smart Flexible Sensing Systems Driven by Machine Learning and Artificial Synapses

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Nano-Micro Letters 2024年第1期16卷 235-273页

作者： Tianming Sun Bin Feng Jinpeng huo Yu Xiao Wengan Wang Jin Peng Zehua Li Chengjie Du Wenxian Wang Guisheng Zou Lei Liu Department of Mechanical Engineering State Key Laboratory of Tribology in Advanced EquipmentKey Laboratory for Advanced Manufacturing by Materials Processing TechnologyMinistry of Education of PR ChinaTsinghua UniversityBeijing 100084People’s Republic of China College of Materials Science and Engineering Shanxi ProvinceTaiyuan University of TechnologyTaiyuan 030024People’s Republic of China

The recent wave of the artificial intelligence(AI)revolution has aroused unprecedented interest in the intelligentialize of human *** an essential component that bridges the physical world and digital signals,flexible sensors are evolving from a single sensing element to a smarter system,which is capable of highly efficient acquisition,analysis,and even perception of vast,multifaceted *** challenging from a manual perspective,the development of intelligent flexible sensing has been remarkably facilitated owing to the rapid advances of brain-inspired AI innovations from both the algorithm(machine learning)and the framework(artificial synapses)*** review presents the recent progress of the emerging AI-driven,intelligent flexible sensing *** basic concept of machine learning and artificial synapses are *** new enabling features induced by the fusion of AI and flexible sensing are comprehensively reviewed,which significantly advances the applications such as flexible sensory systems,soft/humanoid robotics,and human activity *** two of the most profound innovations in the twenty-first century,the deep incorporation of flexible sensing and AI technology holds tremendous potential for creating a smarter world for human beings.

关键词： Flexible electronics Wearable electronics Neuromorphic Memristor Deep learning

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Effects of ulinastatin combined with dexmedetomidine on cognitive dysfunction and emergence agitation in elderly patients who underwent total hip arthroplasty

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World Journal of Psychiatry 2024年第1期14卷 26-35页

作者： Qi-Fan huo Li-Juan Zhu Jian-Wei Guo Yan-An Jiang Jing Zhao Department of Anesthesiology Shaanxi Provincial People’s HospitalXi’an 710068Shaanxi ProvinceChina

BACKGROUND With the continuous growth of the modern elderly population,the risk of fracture *** fracture is a common type of fracture in older *** hip arthroplasty(THA)has significant advantages in relieving chronic pain and promoting the recovery of hip joint *** To investigate the effect of ulinastatin combined with dexmedetomidine(Dex)on the incidences of postoperative cognitive dysfunction(POCD)and emergence agitation in elderly patients who underwent *** A total of 397 patients who underwent THA from February 2019 to August *** conducted a three-year retrospective cohort study in Shaanxi Provincial People’s *** demographic data were obtained from the electronic medical record *** collected preoperative,intraoperative,and postoperative *** hundred twenty-nine patients who were administered Dex during the operation were included in the Dex *** hundred fifty patients who were intravenously injected with ulinastatin 15 min before anesthesia induction were included in the ulinastatin *** hundred eighteen patients who were administered ulinastatin combined with Dex during the operation were included in the Dex+ulinastatin *** patients’perioperative conditions,hemodynamic indexes,postoperative Mini-Mental State Examination(MMSE)scores,Ramsay score,incidence of POCD,and serum inflammatory cytokines were *** There was a significant difference in the 24 h visual analogue scale score among the three groups,and the score in the Dex+ulinastatin group was the lowest(P<0.05).Compared with the Dex and ulinastatin group,the MMSE scores of the Dex+ulinastatin group were significantly increased at 1 and 7 d after the operation(all P<0.05).Compared with those in the Dex and ulinastatin groups,incidence of POCD,levels of serum inflammatory cytokines in the Dex+ulinastatin group were significantly decreased at 1 and 7 d after the operation(all P<0.05).The observer’s assessment of th

关键词： Ulinastatin Dexmedetomidine Postoperative cognitive dysfunction Inflammatory cytokines Total hip arthroplasty

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Insights from TARGET-seq:Inflammation drives TP53-mediated clonal evolution

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The Innovation 2024年第2期5卷 7-8页

作者： Yeqian Zhao Wenxuan huo Yue Liang Xiaodong Mo Shanshan Pei Yanmin Zhao Bone Marrow Transplantation Center the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Liangzhu Laboratory Zhejiang University Medical CenterHangzhou 311121China Institute of Hematology Zhejiang UniversityHangzhou 311121China Peking University People’s Hospital Peking University Institute of HematologyNational Clinical Research Center for Hematologic DiseaseBeijing 100044China

Approximately 10%–20%myeloproliferative neoplasms(MPNs)can progress into blast-phase MPNs,also termed secondary acute myeloid leukemias(sAMLs),presenting dismal *** exhibits a distinctive clinical and pathological profile compared to de novo AML,marked by a higher incidence of erythroid leukemias and reduced responsive to conventional chemotherapies,resulting in a median survival of approximately 6 ***53 alterations are prevalent adverse events in leukemic transformation(LT),occurring in around one-third of sAML subjects.

关键词： TP53 neoplasms alterations

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A breathable, designable and flexible leather–heater used in wearable thermotherapy

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Science China(Technological Sciences) 2024年第7期67卷 2125-2132页

作者： ZHU JingYu LIU YaDong XIE RuiJie ZHAO YuHan WANG Feng LIU YunQing ZHA BaoLi WU JianSheng huo FengWei Key Laboratory of Flexible Electronics(KLOFE) School of Flexible Electronics(Future Technologies)Institute of Advanced Materials(IAM)Nanjing Tech UniversityNanjing 211816China The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen 361005China Tan Kah Kee Innovation Laboratory Xiamen 361102China

Flexible heaters with personal thermal management capabilities have great potential in thermal therapy applications due to their excellent flexibility, low power consumption, and portability. However, manufacturing wearable heating devices that are breathable, wear resistant and conformal for long-term use is still challenging. To address these issues, we designed a leather heater using breathable, biocompatible, and tailorable leather as the substrate through a simple in-situ polymerization polypyrrole strategy. This heater exhibits excellent heating and mechanical properties(reaching 64℃ at a voltage of 5 V with efficient Joule heat generation of 2286 W/m^(2)and uniform temperature distribution, and functioning properly after 1000 cycles of bendability tests). In addition, this heater displays better wear resistance and water vapor permeability rate(38.04 g/(m^(2)h)). The cuttable and sewable of leather gives the strategy ability to be flexibly designed to mold the heater to the specific requirements of different body parts, providing a new approach to wearable thermal therapy.

关键词： flexible electronics leather thermotherapy

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Ascending phase of solar cycle 25 tilts the current El Ni?o-Southern oscillation transition

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Atmospheric and Oceanic Science Letters 2024年第1期 36-40页

作者： Wenjuan huo Ziniu Xiao Liang Zhao Fei Liu GEOMAR Helmholtz Centre for Ocean Research State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of Sciences School of Atmospheric Sciences Sun Yat-Sen UniversityKey Laboratory of Tropical Atmosphere-Ocean SystemMinistry of Educationand Southern Marine Science and Engineering Guangdong Laboratory

自2020年初夏,赤道太平洋地区出现拉尼娜现象并持续两年半多(以下简称2020拉尼娜),对其未来演变的预测引起了很多关注,考虑到11年太阳周期活动对热带太平洋SST异常可能存在锁相影响,本研究分析了当前太阳活动周(即第25太阳周(SC25))对... 详细信息

自2020年初夏,赤道太平洋地区出现拉尼娜现象并持续两年半多(以下简称2020拉尼娜),对其未来演变的预测引起了很多关注,考虑到11年太阳周期活动对热带太平洋SST异常可能存在锁相影响,本研究分析了当前太阳活动周(即第25太阳周(SC25))对目前热带太平洋ENSO现象未来演变的调节作用,基于历史太阳周的统计特征,作者对第25太阳周达到其最大值的时间提出三种可能的情景,并讨论了不同情景下的太阳活动对未来两年ENSO演变的可能影响,第25太阳周的持续上升阶段在一定程度上抑制了当前2023厄尔尼诺现象发展为超级事件.

关键词：厄尔尼诺-南方涛动太阳活动热带太平洋位相转变预测三重拉尼娜现象

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Institutional Inclusiveness

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China Weekly 2024年第9期 37-39页

作者： huo Siyi 不详

More institutional reform and openness are required in achieving high-quality economic development,says Tsinghua expert On July 18,the 20th Central Committeeof the Communist Party of China(CPC)concluded its third plenary session in Beijing,issuing a Communiquéthat describes opening up as"a defining feature of Chinese modernization."The resolution adopted at the session focuses on further deepening reform comprehensively to advance Chinese modernization and renewing the country's plan for opening up.

关键词： deepening modernization session

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An End-To-End Hyperbolic Deep Graph Convolutional Neural Network Framework

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Computer Modeling in Engineering & Sciences 2024年第4期139卷 537-563页

作者： Yuchen Zhou Hongtao huo Zhiwen Hou Lingbin Bu Yifan Wang Jingyi Mao Xiaojun Lv Fanliang Bu School of Information Network Security People’s Public Security University of ChinaBeijing100038China Institute of Computing Technology China Academy of Railway Sciences Corporation LimitedBeijing100081China

Graph Convolutional Neural Networks(GCNs)have been widely used in various fields due to their powerful capabilities in processing graph-structured ***,GCNs encounter significant challenges when applied to scale-free graphs with power-law distributions,resulting in substantial ***,most of the existing GCN models are shallow structures,which restricts their ability to capture dependencies among distant nodes and more refined high-order node features in scale-free graphs with hierarchical *** more broadly and precisely apply GCNs to real-world graphs exhibiting scale-free or hierarchical structures and utilize multi-level aggregation of GCNs for capturing high-level information in local representations,we propose the Hyperbolic Deep Graph Convolutional Neural Network(HDGCNN),an end-to-end deep graph representation learning framework that can map scale-free graphs from Euclidean space to hyperbolic *** HDGCNN,we define the fundamental operations of deep graph convolutional neural networks in hyperbolic ***,we introduce a hyperbolic feature transformation method based on identity mapping and a dense connection scheme based on a novel non-local message passing *** addition,we present a neighborhood aggregation method that combines initial structural featureswith hyperbolic attention *** the above methods,HDGCNN effectively leverages both the structural features and node features of graph data,enabling enhanced exploration of non-local structural features and more refined node features in scale-free or hierarchical *** results demonstrate that HDGCNN achieves remarkable performance improvements over state-ofthe-art GCNs in node classification and link prediction tasks,even when utilizing low-dimensional embedding ***,when compared to shallow hyperbolic graph convolutional neural network models,HDGCNN exhibits notable advantages and performance enhanceme

关键词： Graph neural networks hyperbolic graph convolutional neural networks deep graph convolutional neural networks message passing framework

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Surgical management of adult hand macrodactyly in a 49-year-old patient:A case report

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World Journal of Clinical Cases 2024年第22期12卷 5236-5244页

作者： chao-Jian Pang Xiao-Yan huo Yuan Liu Zong-You Yang Lu Liu Xiao-Bo Fan Shang-Wen Xu Department of Orthopaedic Surgery The First Hospital of HandanHandan 050000Hebei ProvinceChina Department of Orthopaedic Surgery The Third Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina Department of Health Management Hebei Provincial Hospital of Traditional Chinese MedicineShijiazhuang 050000Hebei ProvinceChina Department of Hand Surgery The First Hospital of HandanHandan 050000Hebei ProvinceChina

BACKGROUND Macrodactyly is a rare congenital malformation characterized by an increase in the size of all structures of a digit,accounting for less than 1%of all congenital upper extremity *** SUMMARY We report a case involving a 49-year-old woman who presented for the first time with untreated,radial-sided hand *** performed soft tissue debulking,amputation,median nerve neurotomy and coaptation,and carpal tunnel *** the 6-year follow-up,no significant growth was observed in the bone or soft tissue of the affected *** Tissue overgrowth in patients with progressive macrodactyly can continue and progress excessively with *** nerve neurotomy and coaptation play a crucial role in preventing recurrence of the deformity.

关键词： Macrodactyly Surgery Management Hand Case report

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Society Who Cares?

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China Weekly 2024年第7期 32-35页

作者： huo Siyi 不详

As the impact of China's rapidly aging society increases,experts are urgently calling on authorities to roll out a national insurance scheme to address the dearth of long-term care for the country's seniors.

关键词： authorities insurance senior

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