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Computed tomography-based radiomics diagnostic approach for differential diagnosis between early-and late-stage pancreatic ductal adenocarcinoma

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1256-1267页

作者： Shuai Ren Li-Chao Qian Ying-Ying Cao Marcus J Daniels Li-Na Song Ying Tian zhong-qiu Wang Department of Radiology Jiangsu Province Hospital of Chinese MedicineAffiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Department of Geratology Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese MedicineNanjing 210022Jiangsu ProvinceChina Department of Radiology NYU Langone HealthNew YorkNY 10016United States

BACKGROUND One of the primary reasons for the dismal survival rates in pancreatic ductal adenocarcinoma(PDAC)is that most patients are usually diagnosed at late *** is an urgent unmet clinical need to identify and develop diagnostic methods that could precisely detect PDAC at its earliest *** A total of 71 patients with pathologically proved PDAC based on surgical resection who underwent contrast-enhanced computed tomography(CT)within 30 d prior to surgery were included in the *** staging was performed in accordance with the 8th edition of the American Joint Committee on Cancer staging *** features were extracted from the region of interest(ROI)for each patient using Analysis Kit *** most important and predictive radiomics features were selected using Mann-Whitney U test,univar-iate logistic regression analysis,and minimum redundancy maximum relevance(MRMR)*** forest(RF)method was used to construct the radiomics model,and 10-times leave group out cross-validation(LGOCV)method was used to validate the robustness and reproducibility of the *** A total of 792 radiomics features(396 from late arterial phase and 396 from portal venous phase)were extracted from the ROI for each patient using Analysis Kit *** most important and predictive features were selected using Mann-Whitney U test,univariate logistic regression analysis,and MRMR *** method was used to construct the radiomics model with the nine most predictive radiomics features,which showed a high discriminative ability with 97.7%accuracy,97.6%sensitivity,97.8%specificity,98.4%positive predictive value,and 96.8%negative predictive *** radiomics model was proved to be robust and reproducible using 10-times LGOCV method with an average area under the curve of 0.75 by the average performance of the 10 newly built *** The radiomics model based on CT could serve as a promising non-invasive method in differential diag

关键词： Pancreatic ductal adenocarcinoma Radiomics Computed tomography American Joint Committee on Cancer staging

Hyphae-mediated bioassembly of carbon fibers derivatives for advanced battery energy storage

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Carbon Energy 2024年第6期6卷 140-150页

作者： Lei Huang zhong qiu Ping Liu Xinhui Xia Feng Cao Xinping He Chen Wang Wangjun Wan Yongqi Zhang Yang Xia Wenkui Zhang Minghua Chen Jiancang Zhou Department of Critical Care Medicine Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhouChina State Key Laboratory of Silicon Materials Key Laboratory of Advanced Materials and Applications for Batteries of Zhejiang ProvinceSchool of Materials Science&EngineeringZhejiang UniversityHangzhouChina College of Materials Science&Engineering Zhejiang University of TechnologyHangzhouChina State Key Laboratory of Photocatalysis on Energy and Environment Fuzhou UniversityFuzhouChina Department of Engineering Technology Huzhou CollegeHuzhouChina Zhejiang Academy of Science and Technology for Inspection&Quarantine HangzhouZhejiangChina Institute of Fundamental and Frontier Science University of Electronic Science and Technology of ChinaChengduChina Key Laboratory of Engineering Dielectric and Applications(Ministry of Education) School of Electrical and Electronic EngineeringHarbin University of Science and TechnologyHarbinChina

Ingenious design and fabrication of advanced carbon-based sulfur cathodes are extremely important to the development of high-energy lithium-sulfur batteries,which hold promise as the next-generation power ***,for the first time,we report a novel versatile hyphae-mediated biological assembly technology to achieve scale production of hyphae carbon fibers(HCFs)derivatives,in which different components including carbon,metal compounds,and semiconductors can be homogeneously assembled with HCFs to form composite *** mechanism of biological adsorption assembly is also *** a representative,reduced graphene oxides(rGOs)decorated with hollow carbon spheres(HCSs)successfully co-assemble with HCFs to form HCSs@rGOs/HCFs hosts for sulfur *** this unique architecture,not only large accommodation space for sulfur but also restrained volume expansion and fast charge transport paths are ***,multiscale physical barriers plus chemisorption sites are simultaneously established to anchor soluble lithium ***,the designed HCSs@rGOs/HCFs-S cathodes deliver a high capacity(1189 mA h g^(-1)at 0.1 C)and good high-rate capability(686 mA h g^(-1)at 5 C).Our work provides a new approach for the preparation of high-performance carbon-based electrodes for energy storage devices.

关键词： bioassembly carbon fibers energy storage graphene lithium-sulfur batteries

Recent progress of two-dimensional metal-base catalysts in urea oxidation reaction

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Rare Metals 2024年第8期43卷 3607-3633页

作者： Qi-Xiang Huang Fang Wang Yong Liu Bi-Ying Zhang Fang-Ya Guo zhong-qiu Jia Hao Wang Tian-Xiang Yang Hai-Tao Wu Feng-Zhang Ren Ting-Feng Yi School of Materials Science and Engineering Henan University of Science and TechnologyLuoyang 471000China School of Environmental Engineering and Chemistry Luoyang Institute of Science and TechnologyLuoyang 471023China Henan Province International Joint Laboratory of Materials for Solar Energy Conversion and Lithium Sodium Based Battery Luoyang 471023China School of Chemistry and Life Sciences Suzhou University of Science and TechnologySuzhou 215009China School of Materials Science and Engineering Northeastern UniversityShenyang110819China

Urea oxidation reaction(UOR)is an auxiliary water electrolysis hydrogen production technology developed in recent years to replace oxygen evolution reaction and reduce energy consumption,which can produce hydrogen more efficiently by low theoretical potential,reduce the average cost of electrochemical hydrogen production,and is a frontier research hotspot for renewable hydrogen ***-dimensional(2D)nanomaterials as electrocatalysts have many favorable potential,such as it can effectively reduce the resistivity of materials and increase the specific surface area with *** paper reviews the application of 2D materials in UOR in alkaline *** a cross-sectional comparison of various material performance data including overpotential,Tafel slope,electrochemical active surface area(ECSA)and it stability test was conducted,which could illustrate the differences between materials composed of different *** addition,the main challenges hindering the progress of research on 2D materials in urea electrocatalysis processes and promising materials in this field in future are summarized and *** is believed that this review will contribute to designing and analyzing highperformance 2D urea electrocatalysts for water splitting.

关键词： Water splitting Urea oxidation reaction Two-dimensional Transition metal compounds Noble/non-noble metals

Prevalence and risk factors of depression among patients with perianal fistulizing Crohn’s disease

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World Journal of Psychiatry 2024年第5期14卷 715-725页

作者： Jing Li Wing-Yi Ng Li-Chao Qiao Fen Yuan Xing Lan Li-Bei Zhu Bo-Lin Yang zhong-qiu Wang Department of Radiology Jiangsu Province Hospital of Chinese Medicine Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Department of Acupuncture and Rehabilitation Jiangsu Province Hospital of Chinese Medicine Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Department of Colorectal Surgery Jiangsu Province Hospital of Chinese Medicine Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina

BACKGROUND Psychological distress,especially depression,associated with perianal fistulizing Crohn’s disease(PFCD)is widespread and ***,there is a surprising paucity of studies to date that have sought to identify the prevalence and risk factors of depression associated with *** To estimate the prevalence of depressive symptoms and investigate the depression-related risk factors in patients with *** The study was conducted in the form of survey and clinical data collection via questionnaire and specialized medical *** symptoms,life quality,and fatigue severity of patients with PFCD were assessed by Patient Health Questionnaire-9,Inflammatory Bowel Disease Patient Quality of Life Questionnaire(IBDQ),and Inflammatory Bowel Disease(IBD)Fatigue Patient Self-assessment *** basic demographic information,overall disease features,perianal clinical information,and laboratory inflammation indicators were also *** regression analysis was ultimately used to ascertain the risk factors of depression associated with *** A total of 123 patients with PFCD were involved,and 56.91%were suffering from *** to multivariate logistic regression analysis,Perianal Disease Activity Index(PDAI)score[odds ratio(OR)=0.69,95%confidence interval(CI):0.50 to 0.95],IBDQ score(OR=0.93,95%CI:0.88 to 0.97),modified Van Assche index(OR=1.24,95%CI:1.01 to 1.53),and IBD Fatigue score(OR=1.72,95%CI:1.23 to 2.42)were independent risk factors of depression-related prevalence among patients with PFCD(P<0.05).Multiple linear regression analysis revealed that the increasing perianal modified Van Assche index(βvalue=0.166,95%CI:0.02 to 0.31)and decreasing IBDQ score(βvalue=-0.116,95%CI:-0.14 to-0.09)were independently associated with the severity of depression(P<0.05).CONCLUSION Depressive symptoms in PFCD patients have significantly high *** score,modified Van Assche index,quality of life,and fatigue severity

关键词： Crohn’s disease Fistula Depression Inflammatory bowel diseases Risk factors

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中国餐饮消费驱动的温室气体跨产业传导机制

中国环境科学 2024年第9期44卷 5321-5328页

作者：磨昕钟秋萌梁赛广东工业大学生态环境与资源学院湾区生态安全与绿色发展基础研究卓越中心大湾区城市环境安全与绿色发展教育部重点实验室广东广州510006

基于环境投入产出模型、结构路径分析和介数中心性方法揭示了中国餐饮消费驱动的温室气体(GHG)跨产业传导机制(包括重要传导路径和关键控制节点).结果表明:(1)2002~2020年间中国餐饮业GHG足迹在波动中增加.畜牧业→屠宰及肉类加工业→... 详细信息

基于环境投入产出模型、结构路径分析和介数中心性方法揭示了中国餐饮消费驱动的温室气体(GHG)跨产业传导机制(包括重要传导路径和关键控制节点).结果表明:(1)2002~2020年间中国餐饮业GHG足迹在波动中增加.畜牧业→屠宰及肉类加工业→餐饮业→城镇居民消费、畜牧业→餐饮业→城镇居民消费是对餐饮业GHG足迹贡献最大的2条传导路径,种植业、畜牧业、电力热力的生产和供应业是传导路径涉及较多的起点部门.所识别的重要传导路径是餐饮业低碳发展决策的重要抓手.(2)屠宰及肉类加工业、谷物加工业、植物油加工业是餐饮业GHG足迹在产业链中隐含传输的关键控制节点,其2020年传输的隐含GHG规模分别为12.2, 8.0和7.0Mt CO_(2)-eq,应关注这些部门的生产效率提升以降低餐饮业GHG足迹.(3)2002~2020年间谷物加工业、电力热力的生产和供应业等部门的控制节点作用逐渐增强.

关键词：餐饮业温室气体投入产出分析结构路径分析网络分析

Biomimetic natural biomaterials for tissue engineering and regenerative medicine:new biosynthesis methods,recent advances,and emerging applications

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Military Medical Research 2024年第1期11卷 50-79页

作者： Shuai Liu Jiang-Ming Yu Yan-Chang Gan Xiao-zhong qiu Zhe-Chen Gao Huan Wang Shi-Xuan Chen Yuan Xiong Guo-Hui Liu Si-En Lin Alec McCarthy Johnson V.John Dai-Xu Wei Hong-Hao Hou Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering the Fifth Affiliated HospitalSchool of Basic Medical ScienceSouthern Medical UniversityGuangzhou 510900China Department of Orthopedics Tongren HospitalShanghai Jiao Tong UniversityShanghai 200336China The Eighth Affiliated Hospital Sun Yat-Sen UniversityShenzhen 518033GuangdongChina Engineering Research Center of Clinical Functional Materials and Diagnosis&Treatment Devices of Zhejiang Province Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhou 325011ZhejiangChina Department of Orthopedics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Orthopaedics and Traumatology Faculty of Medicinethe Chinese University of Hong KongHong Kong SAR 999077China Department of Functional Materials Terasaki Institute for Biomedical InnovationLos AngelesCA 90064USA Mary&Dick Holland Regenerative Medicine Program College of MedicineUniversity of Nebraska Medical CenterOmahaNE 68130USA Zigong Affiliated Hospital of Southwest Medical University Zigong Psychiatric Research CenterZigong Institute of Brain ScienceZigong 643002SichuanChina Key Laboratory of Resource Biology and Biotechnology in Western China Ministry of EducationSchool of MedicineDepartment of Life Sciences and MedicineNorthwest UniversityXi’an 710127China

Biomimetic materials have emerged as attractive and competitive alternatives for tissue engineering(TE)and regenerative *** contrast to conventional biomaterials or synthetic materials,biomimetic scaffolds based on natural biomaterial can offer cells a broad spectrum of biochemical and biophysical cues that mimic the in vivo extracellular matrix(ECM).Additionally,such materials have mechanical adaptability,micro-structure interconnectivity,and inherent bioactivity,making them ideal for the design of living implants for specific applications in TE and regenerative *** paper provides an overview for recent progress of biomimetic natural biomaterials(BNBMs),including advances in their preparation,functionality,potential applications and future *** highlight recent advances in the fabrication of BNBMs and outline general strategies for functionalizing and tailoring the BNBMs with various biological and physicochemical characteristics of native ***,we offer an overview of recent key advances in the functionalization and applications of versatile BNBMs for TE ***,we conclude by offering our perspective on open challenges and future developments in this rapidly-evolving field.

关键词： Biomimic Scaffold Biosynthesis Natural biomaterial Tissue engineering

Factors influencing further vertebral height loss following percutaneous vertebroplasty in osteoporotic vertebral compression fractures:A 1-year follow-up study

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World Journal of Clinical Cases 2024年第21期12卷 4609-4617页

作者： zhong-qiu Tang Shao-Bo He Dong-Yang Yu Hai-Mao Luo Xue-Hong Xing Yong-Wen Zhou Department of Spinal Surgery Affiliated Hospital of Panzhihua UniversityPanzhihua 617000Sichuan ProvinceChina Department of Shoulder and Elbow Surgery Affiliated Hospital of Panzhihua UniversityPanzhihua 617000Sichuan ProvinceChina

BACKGROUND Osteoporotic vertebral compression fractures(OVCFs)contribute to back pain and functional limitations in older individuals,with percutaneous vertebroplasty(PVP)emerging as a minimally invasive ***,further height loss post-PVP prompts investigation into contributing *** To investigate the factors associated with further height loss following PVP with cement augmentation in OVCF *** A total of 200 OVCF patients who underwent successful PVP between January 2021 and December 2022 were included in this study.“Further height loss”during 1 year of follow-up in OVCF patients with bone edema was defined as a vertical height loss of≥4 *** study population was divided into two groups for analysis:The“No Further Height Loss group(n=179)”and the“Further Height Loss group(n=21).”RESULTS In comparing two distinct groups of patients,significant differences existed in bone mineral density(BMD),vertebral compression degree,prevalence of intravertebral cleft(IVF),type of bone cement used,and cement distribution *** from binary univariate regression analysis revealed that lower BMD,the presence of IVF,cleft distribution of bone cement,and higher vertebral compression degree were all significantly associated with further height ***,the use of mineralized collagen modified-poly(methyl methacrylate)bone cement was associated with a significant reduction in the risk of further height *** multivariate regression analysis,lower BMD and the presence of IVF remained significantly associated with further height *** Further height loss following PVP in OVCF patients is influenced by a complex interplay of factors,especially lower BMD and the presence of *** findings underscore the importance of assessing and managing these factors when addressing height loss following PVP in OVCF patients.

关键词： Percutaneous vertebroplasty Osteoporotic vertebral compression fractures Further height loss Bone mineral density Intravertebral cleft

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新会计制度下中学预算绩效管理优化研究

教育财会研究 2024年第3期35卷 92-95页

作者：仲秋北京大学附属中学财务办公室北京100190

政府绩效管理体系的高质效运行离不开政府会计制度的有力支持。作为中学预算管理的核心内容,绩效管理是实现资源有效配置和效率最大化的重要手段。中学预算管理直接影响绩效管理水平,对办学目标的实现具有重要影响。随着政府会计制度的... 详细信息

政府绩效管理体系的高质效运行离不开政府会计制度的有力支持。作为中学预算管理的核心内容,绩效管理是实现资源有效配置和效率最大化的重要手段。中学预算管理直接影响绩效管理水平,对办学目标的实现具有重要影响。随着政府会计制度的推出,中学预算管理面临新的机遇和挑战,科学化、严密化、精细化的预算编制成为新会计制度对中学预算绩效管理的新要求。对标新要求,中学预算管理存在预算编制不科学、对预算项目库建设不重视、预算绩效管理部门彼此信息闭塞、联动性不足以及预算绩效管理监督机制建设不健全等问题。为此,本文针对性地提出加强中学预算绩效管理的建议,以期不断优化中学预算绩效管理,提升管理质效。

关键词：政府会计制度中学预算管理绩效管理优化策略

景观生态风险演变及其对驱动因素的响应--以北京生态涵养区为例

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中国环境科学 2024年第7期44卷 4031-4041页

作者：高林赵中秋宋东阳裴小龙中国地质大学(北京)土地科学技术学院北京100083 自然资源部土地整治重点实验室北京100035 中国地质调查局廊坊自然资源综合调查中心河北廊坊065000 自然资源要素耦合过程与效应重点实验室北京100055

基于1990~2020年土地利用/覆被数据,建立了景观生态风险评价模型,对30a间北京生态涵养区景观生态风险时空演变特征进行探究,并使用地理探测器模型,分析了自然与人为因素对景观生态风险的驱动作用.结果表明,研究区土地利用类型以林地与... 详细信息

基于1990~2020年土地利用/覆被数据,建立了景观生态风险评价模型,对30a间北京生态涵养区景观生态风险时空演变特征进行探究,并使用地理探测器模型,分析了自然与人为因素对景观生态风险的驱动作用.结果表明,研究区土地利用类型以林地与耕地为主,1990~2020年间,土地利用变化主要呈现林地、建设用地、水域增加,耕地、草地、未利用地减少的趋势.近30a间,景观生态风险持续下降,中、较高、高生态风险区分别下降8.45%、13.66%、8.13%,低、较低生态风险区分别增加2124.34,1247.96km^(2),在空间尺度上呈现正相关性.单因子探测中,人为干扰度、NDVI、高程是驱动景观生态风险变化的主要因素,双因子交互探测结果全部呈现双因子增强和非线性增强,人为干扰度与其他因子相互作用是景观生态风险演变的主要原因.本研究揭示了30a间北京生态涵养区土地利用格局与景观生态风险变化,探究了景观生态风险演变的驱动因素,为北京生态涵养区保持生态稳定、促进绿色发展提供科学依据.

关键词：景观生态风险评价土地利用北京生态涵养区地理探测器