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冷喷涂CoNiCrAlY涂层制备工艺及组织性能研究

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材料研究与应用 2024年第4期18卷 643-648页

作者：邹旸王高民张志远邓春明褚欣谢迎春中国航发南方工业有限公司湖南株洲412002 广东省科学院新材料研究所/广东省现代表面工程技术重点实验室/粤港现代表面工程技术联合实验室广东广州510650

CoNiCrAlY合金可用于航空发动机热端部件的高温涂层,其使用性能因制备工艺的不同而呈现出差异。传统热喷涂技术在制备涂层过程中会引入高温热源,可导致材料发生相变,且产生一定的热应力。为消除热应力,需在喷涂至一定厚度后对涂层进行... 详细信息

CoNiCrAlY合金可用于航空发动机热端部件的高温涂层,其使用性能因制备工艺的不同而呈现出差异。传统热喷涂技术在制备涂层过程中会引入高温热源,可导致材料发生相变,且产生一定的热应力。为消除热应力,需在喷涂至一定厚度后对涂层进行热处理,这导致了热喷涂技术制备大厚度涂层时喷涂效率的降低和成本的增加。围绕航空发动机涡轮外环高温封严涂层新一代制备技术需求,采用高压冷喷涂技术,以氮气为载气,国产CoNiCrAlY粉末为原料,开展了低成本冷喷涂CoNiCrAlY涂层的制备工艺及组织性能研究。实验采用φ100.50 mm 304不锈钢管基体,在69°喷涂角度、5 MPa喷涂压力下,分别在800、850和900℃喷涂温度条件下沉积制备了CoNiCrAlY涂层。测量了粉末在不同喷涂温度下的沉积效率,表征了涂层的微观结构、显微硬度和摩擦磨损性能,以1050℃保温5 h随炉冷却方式对涂层进行了真空热处理,研究了热处理后涂层的组织与性能变化。结果显示,涂层孔隙率随喷涂温度的升高而降低(2.07%、0.81%和0.44%),粉末颗粒的沉积效率随喷涂温度的升高而提高(29.7%、32.5%和36.1%),喷涂态涂层的显微硬度与喷涂温度之间无线性关系(585.32、526.21和563.52 HV_(0.3))。经真空热处理后,冷喷涂CoNiCrAlY涂层孔隙率均显著降低,均下降至0.4%左右。显微硬度显著下降,保持在360 HV_(0.3)左右。摩擦磨损测试结果表明,较低喷涂温度制备的CoNiCrAlY涂层,经真空热处理后具有更低的磨损率。

关键词：冷喷涂 CoNiCrAlY涂层气体温度孔隙率真空热处理显微硬度摩擦磨损沉积效率

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Patient-derived xenograft platform of OSCC： a renewable human bio-bank for preclinical cancer research and a new co-clinical model for treatment optimization

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Frontiers of Medicine 2016年第1期10卷 104-110页

作者： Shuyang Sun zhiyuan zhang Department of Oral and Maxillofacial-Head Neck Oncology Ninth People's Hospital Shanghai Jiao Tong University School of Medicine'Shanghai Key Laboratory of Stomatology Shanghai 200011 China

Advances in next-generation sequencing and bioinformatics have begun to reveal the complex genetic landscape in human cancer genomes, including oral squamous cell carcinoma （OSCC）. Sophisticated preclinical models that fully represent intra- and inter-tumoral heterogeneity are required to understand the molecular diversity of cancer and achieve the goal of personalized therapies. Patient-derived xenograft （PDX） models generated from human tumor samples that can retain the histological and genetic features of their donor tumors have been shown to be the preferred preclinical tool in translational cancer research compared with other conventional preclinical models. Specifically, genetically well-defined PDX models can be applied to accelerate targeted antitumor drug development and biomarker discovery. Recently, we have successfully established and characterized an OSCC PDX panel as part of our tumor bio-bank for translational cancer research. In this paper, we discuss the establishment, characterization, and preclinical applications of the PDX models. In particular, we focus on the classification and applications of the PDX models based on validated annotations, including clinicopathological features, genomic profiles, and pharmacological testing information. We also explore the translational value of this well-annotated PDX panel in the development of co-clinical trials for patient stratification and treatment optimization in the near future. Although various limitations still exist, this preclinical approach should be further tested and improved.

关键词： patient-derived xenograft models personalized medicine co-clinical trial patient stratification oral squamous cellcarcinoma

埋弧焊丝用H08Mn钢盘条氧化铁皮研究及其轧制工艺

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热处理 2024年第2期39卷 23-26页

作者：李立仁张志远杨海江赵琼彭兴东山西建龙实业有限公司技术中心山西运城043801 辽宁科技大学材料与冶金学院辽宁鞍山114051

H08Mn钢盘条多用于制作埋弧焊丝,其表面的氧化铁皮对拉拔前机械除鳞效果有明显影响。介绍了盘条氧化铁皮的形成机制、氧化铁皮的种类和构成;采用不同的工艺参数,包括始轧温度、精轧温度、吐丝温度和首道辊速度,轧制了H08Mn钢盘条,随后... 详细信息

H08Mn钢盘条多用于制作埋弧焊丝,其表面的氧化铁皮对拉拔前机械除鳞效果有明显影响。介绍了盘条氧化铁皮的形成机制、氧化铁皮的种类和构成;采用不同的工艺参数,包括始轧温度、精轧温度、吐丝温度和首道辊速度,轧制了H08Mn钢盘条,随后检测了盘条氧化铁皮的厚度、盘条的晶粒度和抗拉强度。结果表明:采用这样的工艺参数即880℃的精轧温度、900℃的吐丝温度和18 m/min(按5%递增)的首段辊道速度轧制的H08Mn钢盘条,其氧化铁皮厚度小于20μm且易剥落,晶粒度和抗拉强度均有利于后续拉拔加工。

关键词： H08Mn钢盘条氧化铁皮机械除鳞轧制工艺

Kill two birds with one stone: A novel dual-functional nanobiomaterial platform with a clear translational potential for bone regeneration

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Nano Research 2020年第9期13卷 2311-2312页

作者： Yu Shrike zhang zhiyuan zhang Division of Engineering in Medicine Department of MedicineBrigham and Womens HospitalHarvard Medical SchoolCambridgeMA02139USA Department of Oral and Maxillofacial Surgery Ninth Peoples HospitalShanghai Jiao Tong UniversityShanghai 200011China

Modulating healing of the bone has been a long-standing theme of both fundam ental and clinical research,which can be greatly aided using a biomaterials approach[1],designed to provide effective cues that are otherwise intrinsically lacking or insufficient in the wounded bone *** in Nano Research,Ye,Khademhosseini,and colleagues report a new nanobiom aterial strategy based on m esoporous silica rods with cone-shaped pores(MSR-CP),to minimize inflammation while maximizing regeneration,for the treatm ent of bone defects[2].

关键词： healing wound otherwise

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10kV氧化锌避雷器故障分析及处置

河北电力技术 2024年第3期43卷 67-70页

作者：张智远李兴权格桑次仁赵猛虎刘宾国网河北省电力有限公司电力科学研究院河北石家庄050021 国网西藏电力有限公司阿里供电公司西藏阿里地区859000

针对一起10kV氧化锌避雷器故障,通过外观检查、例行试验检测、关键部位解体等试验分析,发现其存在密封性不良、工艺设计缺陷、阀片质量不合格等问题。抽检分析了库存(在运)设备,讨论了避雷器的故障机理,认为避雷器密封性能、设备工艺设... 详细信息

针对一起10kV氧化锌避雷器故障,通过外观检查、例行试验检测、关键部位解体等试验分析,发现其存在密封性不良、工艺设计缺陷、阀片质量不合格等问题。抽检分析了库存(在运)设备,讨论了避雷器的故障机理,认为避雷器密封性能、设备工艺设计的紧凑性及内部阀片质量是影响设备整体运行性能的关键因素。同时,从避雷器选型、日常运维、避雷器安装等方面提出了改进建议,将促进设备质量持续提升,保障用户可靠供电。

关键词：氧化锌避雷器例行试验解体分析密封性金属阀片

Predictors of Global Disparities in COVID-19 Vaccination Coverage — 219 Countries and Territories, December 2020–July 2022

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China CDC weekly 2024年第15期6卷 318-323,I0006,I0007页

作者： Ying zhang Shujie Zang Xu zhang Zhiqiang Qu Xinyu Zhou Leesa Lin zhiyuan Hou School of Public Health and Global Health InstituteFudan UniversityShanghaiChina Department of Infectious Disease Epidemiology London School of Hygiene&Tropical MedicineLondonUnited Kingdom Laboratory of Data Discovery for Health(D24H) Hong Kong Science ParkHong Kong Special Administrative RegionChina

What is already known about this topic?The significant disparities in global coronavirus disease 2019(COVID-19)vaccine coverage hamper the pace of epidemic *** is a need to better understand the factors contributing to disparities in COVID-19 vaccination rates across *** is added by this report?This report revealed significant associations between vaccination coverage and various country-level *** pandemic preparedness,higher levels of trust,and a lower proportion of young population aged 0–14 were strongly correlated with higher COVID-19 vaccination *** are the implications for public health practices?Our findings emphasize the need for enhanced pandemic preparedness and governance,coupled with building trust in government and healthcare *** also needs to address the hesitancy of vaccinating children and adolescents aged 0–14 as the vaccination campaign progresses.

关键词： vaccination vaccine COV

Self-cleaning effect and secondary swirling clean gas for suppressing particle deposition on vortex finder of gas cyclones

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Particuology 2024年第7期90卷 72-87页

作者： Zhanpeng Sun Huandi Yang Kaixuan zhang zhiyuan Wang Zhenyuan Hong Guang Yang School of Mechanical Engineering Hebei University of Science&TechnologyShijiazhuang050018China

In order to suppressing the particle deposition on vortex finder,a series of gas cyclones with the secondary swirling clean gas were developed inspired by the gas purge *** of the width and extension length of the flow channel as well as the secondary inlet velocity and running time on the particle deposition pattern,the deposited particle mass and the cyclones'performance were experimentally investigated,*** results show that the ultrafine particles(Stokes number Stk<0.0358)are mainly loose deposited on the walls under the secondary *** to the conventional cyclone with single tangential inlet,the total deposited particle mass of the improved cyclone has a maximum reduction more than 60%,and the collecting efficiency is increased up to 97.5%under the basically same pressure *** corresponding no-deposition area is increased by about 13%,and remains constant in spite of extending the running ***,an interesting phenomenon named"self-cleaning effect"of the vortex finder was captured for the gas cyclones,and mechanism of the secondary clean gas on the particle deposition is preliminarily *** results can deepen the understanding of the particle deposition on the vortex finder and guide the design of the anti-coking gas cyclones.

关键词： Cyclones Vortex finder Particle deposition Gas purge effect Self-cleaning effect

Rational Design of Cost-Effective Metal-Doped ZrO_(2)for Oxygen Evolution Reaction

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Nano-Micro Letters 2024年第9期16卷 385-396页

作者： Yuefeng zhang Tianyi Wang Liang Mei Ruijie Yang Weiwei Guo Hao Li zhiyuan Zeng Department of Materials Science and Engineering and State Key Laboratory of Marine PollutionCity University of Hong Kong83 Tat Chee AvenueKowloon 999077Hong KongPeople’s Republic of China Advanced Institute for Materials Research(WPI‑AIMR) Tohoku UniversitySendai 980‑8577Japan Shenzhen Research Institute City University of Hong KongShenzhen 518057People’s Republic of China Shanxi Supercomputing Center Lvliang 033000ShanxiPeople’s Republic of China

The design of cost-effective electrocatalysts is an open challenging for oxygen evolution reaction(OER)due to the“stable-oractive”*** dioxide(ZrO_(2)),a versatile and low-cost material that can be stable under OER operating conditions,exhibits inherently poor OER activity from experimental ***,we doped a series of metal elements to regulate the ZrO_(2)catalytic activity in OER via spin-polarized density functional theory calculations with van der Waals *** modeling as a function of the OER activity descriptor(G_(O*)-G_(HO*))displays that 16 metal dopants enable to enhance OER activities over a thermodynamically stable ZrO_(2)surface,among which Fe and Rh(in the form of single-atom dopant)reach the volcano peak(*** optimal activity of OER under the potential of interest),indicating excellent OER *** energy diagram calculations,density of states,and ab initio molecular dynamics simulations further showed that Fe and Rh are the effective dopants for ZrO_(2),leading to low OER overpotential,high conductivity,and good *** cost-effectiveness,single-atom Fe doped ZrO_(2)emerged as the most promising catalyst for *** finding offers a valuable perspective and reference for experimental researchers to design cost-effective catalysts for the industrial-scale OER production.

关键词： Oxygen evolution reaction Metal oxide Electrocatalysis Surface Pourbaix analysis Doping

A large-scale screening of metal-organic frameworks for iodine capture combining molecular simulation and machine learning

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Frontiers of Environmental Science & Engineering 2023年第12期17卷 71-84页

作者： Min Cheng zhiyuan zhang Shihui Wang Kexin Bi Kong-qiu Hu Zhongde Dai Yiyang Dai Chong Liu Li Zhou Xu Ji Wei-qun Shi School of Chemical Engineering Sichuan UniversityChengdu 610065China Laboratory of Nuclear Energy Chemistry Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China College of Architecture and Environment Sichuan UniversityChengdu 610065China School of Carbon Neutrality Future Technology Sichuan UniversityChengdu 610065China Department of Bioprocess Engineering Institute of BiotechnologyTechnische Universität BerlinBerlin 10623Germany

We performed large-scale molecular simulation to screen and identify metal-organic framework materials for gaseous iodine capture,as part of our ongoing effort in addressing management and handling issues of various radionuclides in the grand scheme of spent nuclear fuel *** from the computation-ready experimental(CoRE)metal-organic frameworks(MOFs)database,grand canonical Monte Carlo simulation was employed to predict the iodine uptake values of the MOFs.A ranking list of MOFs based on their iodine uptake capabilities was generated,with the Top 10 candidates identified and their respective adsorption sites ***,machine learning was used to establish structure-property relationships to correlate MOFs’various structural and chemical features with their corresponding performances in iodine capture,yielding interpretable common features and design rules for viable MOF *** research strategy and framework of the present study could aid the development of high-performing MOF adsorbents for capture and recovery of radioactive iodine,and moreover,other volatile environmentally hazardous species.

关键词： Iodine capture Metal-organic framework Large-scale screening Molecular simulation Machine learning