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Efficacy analysis of Cheng's GIRAFFE reconstruction after proximal gastrectomy for adenocarcinoma of esophagogastric junction

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Chinese Journal of Cancer Research 2022年第3期34卷 289-297页

作者： zhiyuan xu Can Hu Yanqiang Zhang Ling Huang Litao Yang Jianfa Yu Pengfei Yu Jiahui Chen Yian Du Xiangdong Cheng Department of Gastric Surgery Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital)Institute of Basic Medicine and Cancer(IBMC)Chinese Academy of SciencesHangzhou 310022China Department of Gastrointestinal Surgery the First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310053China

Objective:Reconstruction of the digestive tract for adenocarcinoma of esophagogastric junction(AEG)is in dispute.This study evaluated Cheng’s gastric tube interposition esophagogastrostomy with reconstruction of His angle and fundus(Cheng’s GIRAFFE anastomosis)in laparoscopic/open proximal gastrectomy for Siewert typeⅡAEG,which was performed at Zhejiang Cancer Hospital and the First Affiliated Hospital of Zhejiang Chinese Medical University.Here,we discuss the preliminary results of gastric emptying and anti-reflux.Methods:From a retrospective database,74 patients with advanced Siewert typeⅡAEG underwent curative proximal gastrectomy with GIRAFFE anastomosis,and their gastric emptying and anti-reflux outcomes were evaluated by the Reflux Disease Questionnaire(RDQ)score,nuclide gastric emptying,24-h impedance-pH monitoring and gastroscopy.Results:Seventy-four patients successfully completed proximal partial gastrectomy with Cheng’s GIRAFFE esophagogastric anastomosis.RDQ score six months after the operation was 2.2±2.5.Results of nuclide gastric emptying examinations showed that the gastric half-emptying time was 67.0±21.5 min,the 1-h residual rate was(52.2±7.7)%,the 2-h residual rate was(36.4±5.1)%,and the 3-h residual rate was(28.8±3.6)%;24-h impedance-p H monitoring revealed that the mean De Meester score was 5.8±2.9.Reflux esophagitis was observed by gastroscopy in 7 patients six months after surgery.Conclusions:Cheng’s GIRAFFE anastomosis is safe and feasible for Siewert typeⅡAEG.

关键词： Cheng's GIRAFE anastomosis anti refux Siewert typeⅡAEG proximal gastrectomy

A new pinching theorem for complete self-shrinkers and its generalization

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Science China Mathematics 2020年第6期63卷 1139-1152页

作者： Li Lei Hongwei xu zhiyuan xu Center of Mathem atical Sciences Zhejiang UniversityHangzhou 310027China Departm ent of Mathem atics Hangzhou Normal UniversityHangzhou 310036China

In this paper,we firstly verify that if Mn is an n-dimensional complete self-shrinker with polynomial volume growth in Rn+1,and if the squared norm of the second fundamental form of M satisfies 0≤S-1≤1/18,then S≡1 and M is a round sphere or a cylinder.More generally,let M be a complete λ-hypersurface of codimension one with polynomial volume growth in Rn+1 with λ≠0.Then we prove that there exists a positive constant γ,such that if |λ|≤γ and the squared norm of the second fundamental form of M satisfies0≤S-βλ≤1/18,then S≡βλ,λ> 0 and M is a cylinder.Here βλ=1/2(2+λ2+|λ|(λ2+4)1/2).

关键词： rigidity theorem the second fundamental form self-shrinker λ-hypersurface

On the generalized Chern conjecture for hypersurfaces with constant mean curvature in a sphere

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Science China Mathematics 2021年第7期64卷 1493-1504页

作者： Li Lei Hongwei xu zhiyuan xu Center of Mathematical Sciences Zhejiang UniversityHangzhou 310027China Department of Mathematics Hangzhou Normal UniversityHangzhou 310036China

Let M be a compact hypersurface with constant mean curvature in Denote by H and S the mean curvature and the squared norm of the second fundamental form of M,respectively.We verify that there exists a positive constantγ(n)depending only on n such that if|H|≤γ(n)andβ(n,H)≤S≤β(n,H)+n/18,then S≡β(n,H)and M is a Clifford torus.Here,β(n,H)=n+n^(3)/2(n-1)H^(2)+n(n-2)/2(n-1)(1/2)n^(2)H^(4)+4(n-1)H^(2).

关键词： generalized Chern conjecture hypersurfaces with constant mean curvature rigidity theorem scalar curvature the second fundamental form

Defective Ni_(3)S_(2)nanowires as highly active electrocatalysts for ethanol oxidative upgrading

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Nano Research 2022年第4期15卷 2987-2993页

作者： Yufeng Zhang Wei Zhu Jinjie Fang zhiyuan xu Yanrong xue Di Liu Rui Sui Qingqing Lv xuerui Liu Yongsheng Wang Wei Chen Zhongbin Zhuang State Key Lab of Organic-Inorganic Composites and Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical TechnologyBeijing 100029China Key Laboratory of Carbon Materials of Zhejiang Province College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325035China Beijing Key Laboratory of Energy Environmental Catalysis Beijing University of Chemical TechnologyBeijing 100029China

Electrochemical upgrading of biomass ethanol to value-added chemicals is promising for sustainable society.Here,we synthesize defective Ni_(3)S_(2) nanowires(NWs),which show high activity towards electrochemical oxidation of ethanol to acetate.The Ni_(3)S_(2) NWs are formed by the oriented attachment mechanism,and rich defects are introduced during the growth.A low onset potential of 1.31 V and high mass activity of 8,716 mA·mgNi^(-1) at 1.5 V are achieved using the synthesized Ni_(3)S_(2) NWs toward the ethanol electro-oxidation,which are better than the Ni(OH)2 NWs and the Ni_(3)S_(2) nanoparticles(NPs).And the selectivity for the acetate generation is ca.99%.The high activity of Ni_(3)S_(2) NWs is attributed to the easier oxidation of Ni(II)to the catalytically active Ni(III)species with the promotion from S component and rich defects.These results demonstrate that the defective NWs can be synthesized by the oriented attachment method and the defective Ni_(3)S_(2) NWs structure as the efficient nonnoble metal electrocatalysts for oxidative upgrading of ethanol.

关键词： nickel sulfide electrocatalyst ethanol oxidation defects oriented attachment

Single flow treatment degradation of antibiotics in water using falling-film dielectric barrier discharge

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Plasma Science and Technology 2024年第4期26卷 27-36页

作者：许志远章程伍云健黄邦斗席登科张晓星邵涛 Hubei Engineering Research Center for Safety Monitoring of New Energy and Power Grid Equipment Hubei University of TechnologyWuhan 430068People’s Republic of China Beijing International S&T Cooperation Base for Plasma Science and Energy Conversion Institute of Electrical EngineeringChinese Academy of SciencesBeijing 100190People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China

The environmental contamination caused by antibiotics is increasingly conspicuous due to their widespread manufacture and misuse. Plasma has been employed in recent years for the remediation of antibiotic pollution in the environment. In this work, a falling-film dielectric barrier discharge was used to degrade the antibiotic tetracycline(TC) in water. The reactor combined the gas-liquid discharge and active gas bubbling to improve the TC degradation performance. The discharge characteristics, chemical species’ concentration, and degradation rates at different parameters were systematically studied. Under the optimized conditions(working gas was pure oxygen, liquid flow rate was 100 mL/min, gas flow rate was 1 L/min,voltage was 20 kV, single treatment), TC was removed beyond 70% in a single flow treatment with an energy efficiency of 145 mg/(kW·h). The reactor design facilitated gas and liquid flow in the plasma area to produce more ozone in bubbles after a single flow under pure oxygen conditions, affording fast TC degradation. Furthermore, long-term stationary experiment indicated that long-lived active species can sustain the degradation of TC. Compared with other plasma treatment systems, this work offers a fast and efficient degradation method, showing significant potential in practical industrial applications.

关键词： antibiotic degradation dielectric barrier discharge reactive species single flow treatment

Genetic basis of negative heterosis for growth traits in chickens revealed by genome-wide gene expression pattern analysis

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Journal of Animal Science and Biotechnology 2021年第4期12卷 1267-1280页

作者： Chunning Mai Chaoliang Wen zhiyuan xu Guiyun xu Sirui Chen Jiangxia Zheng Congjiao Sun Ning Yang National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics Breeding and ReproductionMinistry of Agriculture and Rural AffairsChina Agricultural UniversityBeijing 100193China

Background:Heterosis is an important biological phenomenon that has been extensively utilized in agricultural breeding.However,negative heterosis is also pervasively observed in nature,which can cause unfavorable impacts on production performance.Compared with systematic studies of positive heterosis,the phenomenon of negative heterosis has been largely ignored in genetic studies and breeding programs,and the genetic mechanism of this phenomenon has not been thoroughly elucidated to date.Here,we used chickens,the most common agricultural animals worldwide,to determine the genetic and molecular mechanisms of negative heterosis.Results:We performed reciprocal crossing experiments with two distinct chicken lines and found that the body weight presented widely negative heterosis in the early growth of chickens.Negative heterosis of carcass traits was more common than positive heterosis,especially breast muscle mass,which was over−40%in reciprocal progenies.Genome-wide gene expression pattern analyses of breast muscle tissues revealed that nonadditivity,including dominance and overdominace,was the major gene inheritance pattern.Nonadditive genes,including a substantial number of genes encoding ATPase and NADH dehydrogenase,accounted for more than 68%of differentially expressed genes in reciprocal crosses(4257 of 5587 and 3617 of 5243,respectively).Moreover,nonadditive genes were significantly associated with the biological process of oxidative phosphorylation,which is the major metabolic pathway for energy release and animal growth and development.The detection of ATP content and ATPase activity for purebred and crossbred progenies further confirmed that chickens with lower muscle yield had lower ATP concentrations but higher hydrolysis activity,which supported the important role of oxidative phosphorylation in negative heterosis for growth traits in chickens.Conclusions:These findings revealed that nonadditive genes and their related oxidative phosphorylation were the major genetic and molecular factors in the negati

关键词： Chicken Growth Gene expression patterns Heterosis Oxidative phosphorylation

Switched-capacitor Multi-level Inverter with Equal Distribution of the Capacitors Discharging Phases

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Chinese Journal of Electrical Engineering 2020年第4期6卷 42-52页

作者： zhiyuan xu Xiaofeng Zheng Tong Lin Jia Yao Adrian Ioinovici College of Automation Nanjing University of Science and TechnologyNanjing 210014China College of Automation Nanjing University of Aeronautics and AstronauticsNanjing 210016China

A new switched-capacitor(2n+1)levels inverter with a single input source and equal charge of the capacitors at the input voltage V_(in) is presented.Compared with its peers from the same class of inverters,the proposed one features an equal or lower components count referred to the boost factor.And,it presents an additional advantage:each voltage level can be obtained by using different capacitors in the discharging phase,such that the decreasing part of the staircase output waveform can be synthesized with different switching topologies than those used in the increasing part.As a consequence,all the capacitors are discharged at the same voltage value at the end of each half-cycle,allowing for the use of smaller capacitors of equal values.When the capacitors are connected in parallel in the charging phase,there is no need to equalize their voltages,so no additional current spikes appear.This also implies less electromagnetic emission(EMI).Two types of modulation strategies are proposed.A half-height fundamental switching frequency modulation strategy allows for reaching the desired peak of the output voltage during the highest voltage level operation.It is advantageous in application of the inverter as a front end of a grid supplied by green sources of energy.A high frequency(f_(s)=200 kHz)modulation strategy accompanied by a duty-cycle control is advantageous for applications which require miniaturization.A 9-level switched-capacitor multi-level inverter(SCMLI)is analyzed and designed.The power losses are calculated.The experimental results for a 9-level inverter with V_(in)=40 V,V_(out)=110 Vrms 50 Hz,200 W confirm the theoretical expectations.

关键词： Switched-capacitor multi-level inverter half-height frequency modulation

Analysis and Optimization of a Five-phase Hybrid Excitation Flux Switching Machine Based on the Consistency and Complementarity Principle

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Chinese Journal of Electrical Engineering 2021年第3期7卷 52-64页

作者： Ming Cheng zhiyuan xu Minghao Tong Guishu Zhao Peng Han School of Electrical Engineering Southeast UniversityNanjing 210096China School of Mechanical Engineering Nanjing University of Science and TechnologyNanjing 210094China School of Electrical and Automation Engineering Nanjing Normal UniversityNanjing 210023China Ansys Inc.San JoseCA 95134USA

In this study,the general optimal stator poles/rotor teeth(P/T)combination equation of the E-core hybrid excitation flux switching(HEFS)machines are introduced,and a new HEFS machine is proposed and optimized.Firstly,the influences of three different P/T combinations(10/18,10/19,and 10/21)on the HEFS machines are investigated with two-dimensional(2D)finite element analyses(2D-FEA).Meanwhile,the consistency and complementarity principle of the armature windings is analyzed in detail to give reasonable explanations to the simulated results.The general optimal P/T combination equation of the E-core HEFS machines is deduced mathematically to provide an effective guidance on the selection of P/T combinations.The optimal P/T combination calculated by the general equation agrees with the simulated results which confirm the correctness of the mathematical inferences.Finally,the optimizations on the proposed HEFS machine are implemented to obtain higher output torque and better flux-regulation ratio characteristics based on which the cogging torque and torque ripple are reduced significantly.

关键词： Consistence and complementarity principle HEFS machines stator poles/rotor teeth combination

Laparoscopic-assisted radical gastrectomy for distal gastric cancer

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Chinese Journal of Cancer Research 2013年第4期25卷 460-462页

作者： Yian Du Xiangdong Cheng zhiyuan xu Litao Yang Ling Huang Bing Wang Pengfei Yu Ruizeng Dong Department of Abdominal Surgery Zhejiang Cancer Hospital

A 48-year-old female patient was diagnosed with a superficial depressed type early gastric cancer （type IIc） of 1.0 cm at the gastric angle as indicated by gastroscopy. Laparoscopic-assisted greater omentumpreserving D2 radical gastrectomy was performed in combination with Billroth I reconstruction under general anesthesia for the distal gastric cancer on April 5, 2013. The postoperative recovery was satisfying without complications. The patient was discharged seven days after surgery.

关键词： Early gastric cancer gastrectomy laparoscopic-assisted D2 lymph node dissection