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Bioactive Materials 2024年第1期31卷 312-314页

作者： Yifeng Xia Jingnan An Jiaying Li Wenxing gu Yifan Zhang Songsong Zhao Cenzhu Zhao Yang Xu Bin Li zhiyuan Zhong Fenghua Meng Biomedical Polymers Laboratory College of ChemistryChemical Engineering and Materials Scienceand State Key Laboratory of Radiation Medicine and ProtectionSoochow UniversitySuzhou215123PR China College of Pharmaceutical Sciences Soochow UniversitySuzhou215123PR China Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow UniversityInstitute of Blood and Marrow Transplantation of Soochow UniversityCollaborative Innovation Center of HematologySoochow UniversitySuzhou215123PR China Orthopedic Institute Soochow UniversitySuzhou215007PR China

The authors regret to inform that the blot bands of p-AKT in Fig.3C and the third mouse of 4%TPVol group(D9)in Fig.5B were *** mistakes were made during the arrangement of the *** correct form of the two figures are as *** authors apologize for any inconvenience caused and state that this does not change the discussion and the scientific conclusions of the article.

关键词： PLK1 Cor clinical

Directly patterned substrate-free plasmonic “nanograter” structures with unusual Fano resonances

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Light(Science & Applications) 2015年第1期4卷 295-300页

作者： Ajuan Cui Zhe Liu Jiafang Li Tiehan H Shen Xiaoxiang Xia zhiyuan Li Zhijie Gong Hongqiang Li Benli Wang Junjie Li Haifang Yang Wuxia Li Changzhi gu Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China Joule Physics Laboratory School of ComputingScience and EngineeringUniversity of SalfordSalfordM54WTUK School of Physics Science and Engineering Tongji UniversityShanghai200092China Collaborative Innovation Center of Quantum Matter Beijing200092China

The application of three-dimensional(3D)plasmonic nanostructures as metamaterials(MMs),nano-antennas,and other devices faces challenges in producing metallic nanostructures with easily definable orientations,sophisticated shapes,and smooth surfaces that are operational in the optical regime and ***,we demonstrate that complex 3D nanostructures can be readily achieved with focused-ion-beam irradiation-induced folding and examine the optical characteristics of plasmonic“nanograter”structures that are composed of free-standing Au *** 3D nanostructures exhibit interesting 3D hybridization in current flows and exhibit unusual and well-scalable Fano resonances at wavelengths ranging from 1.6 to 6.4 *** the introduction of liquids of various refractive indices to the structures,a strong dependence of the Fano resonance is observed,with spectral sensitivities of 1400 nm and 2040 nm per refractive index unit under figures of merit of 35.0 and 12.5,respectively,for low-order and high-order resonance in the near-infrared *** work indicates the exciting,increasing relevance of similarly constructed 3D free-standing nanostructures in the research and development of photonics and MMs.

关键词： extraordinary Fano resonances plasmonic nanostructures spatially oriented substrate-free three-dimensional

Mercury transformation processes in nature: Critical knowledge gaps and perspectives for moving forward

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Journal of Environmental Sciences 2022年第9期34卷 152-165页

作者： zhiyuan Gao Wang Zheng Yanbin Li Yurong Liu Mengjie Wu Shouying Li Ping Li guangliang Liu Xuewu Fu Shuxiao Wang Feiyue Wang Yong Cai Xinbin Feng Baohua gu Huan Zhong Yongguang Yin Centre for Earth Observation Science and Department of Environment and GeographyUniversity of ManitobaWinnipegMB R3T 2N2Canada Institute of Surface-Earth System Science Tianjin UniversityTianjin 300192China Key Laboratory of Marine Chemistry Theory and Technology Ministry of Education and College of Chemistry and Chemical EngineeringOcean University of ChinaQingdao 266100China State Key Laboratory of Agricultural Microbiology Huazhong Agricultural UniversityWuhan 430070China School of the Environment Nanjing UniversityState Key Laboratory of Pollution Control and Resource ReuseNanjing 210023China State Key Laboratory of Environmental Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China Department of Chemistry and Biochemistry Florida International UniversityMiamiFL 33199USA School of Environment and State Key Joint Laboratory of Environment Simulation and Pollution Control Tsinghua UniversityBeijing 100084China Environmental Sciences Division Oak Ridge National LaboratoryOak RidgeTennessee 37831USA Environmental and Life Sciences Program(EnLS) Trent UniversityPeterboroughOntario K9L 0G2Canada Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China

The transformation of mercury(Hg) in the environment plays a vital role in the cycling of Hg and its risk to the ecosystem and human health. Of particular importance are Hg oxidation/reduction and methylation/demethylation processes driven or mediated by the dynamics of light, microorganisms, and organic carbon, among others. Advances in understanding those Hg transformation processes determine our capacity of projecting and mitigating Hg risk. Here, we provide a critical analysis of major knowledge gaps in our understanding of Hg transformation in nature, with perspectives on approaches moving forward. Our analysis focuses on Hg transformation processes in the environment, as well as emerging methodology in exploring these processes. Future avenues for improving the understanding of Hg transformation processes to protect ecosystem and human health are also explored.

关键词： Mercury oxidation reduction methylation demethylation isotope fractionation

Spontaneous emission in micro-or nanophotonic structures

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PhotoniX 2021年第1期2卷 39-73页

作者： zhiyuan Qian Lingxiao Shan Xinchen Zhang Qi Liu YunMa Qihuang Gong Ying gu State Key Laboratory for Mesoscopic Physics Department of PhysicsPeking UniversityBeijingChina Frontiers Science Center for Nano-optoelectronics Collaborative Innovation Center of Quantum Matterand Beijing Academy of Quantum Information SciencesPeking UniversityBeijingChina Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuanChina Beijing Academy of Quantum Information Sciences Peking UniversityBeijingChina Peking University Yangtze Delta Institute of Optoelectronics NantongChina.

Single-photon source in micro-or nanoscale is the basic building block of on-chip quantum information and scalable quantum *** spontaneous emission based on cavity quantum electrodynamics(CQED)is one of the key principles of realizing single-photon sources fabricated by micro-or nanophotonic *** we mainly review the spontaneous emission of single emitters in micro-or nanostructures,such as whispering gallery microcavities,photonic crystals,plasmon nanostructures,metamaterials,and their *** researches have enriched light-matter interaction as well as made great influence in single-photon source,photonic circuit,and on-chip quantum information.

关键词： Spontaneous emission Cavity quantum electrodynamics Whispering gallery microcavities Photonic crystals Plasmon nanostructures Metamaterials

A21-point finite difference scheme for 2D frequency-domain elastic wave modelling

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A21-point finite difference scheme for 2D frequency-domain e...

Multi-component elastic reverse time migration based on the P-and S-wave separated velocity–stress equations

中国科学院地质与地球物理研究所2013年度（第13届）学术年会

作者： Bingluo gu guanghe Liang zhiyuan Li Key Laboratory of Mineral Resources Institute of Geology and GeophysicsThe Chinese Academy of Sciences College of Earth Sciences University of The Chinese Academy of Sciences

The 21-point finite difference scheme for the frequency-space domain elastic wave forward modelling is designed through optimising the impedance matrix,especially calculating the spatial derivative terms and the mass acceleration terms of the elastic wave displacement equation as accurately as *** tests show that the 21-point finite difference scheme is much better in grid dispersion,memory requirement,and computation time than the 9- point scheme and slightly better than the 25-point *** 21-point finite difference scheme is～15%lower in memory consumption and computing time than the 25-point *** numerical examples show that the 21-point finite difference scheme is valid in the sense of the numerical simulation of ideal models

关键词： 21-point finite difference scheme computing time dispersion frequency domain memory consumption

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Multi-component elastic reverse time migration based on the ...

Degradation Dynamics and Residue Analysis of Flubendiamide in Cabbage and Soil by Liquid Chromatography-Tandem Mass Spectrometry with Dispersive Solid Phase Extraction

中国科学院地质与地球物理研究所2015年度（第15届）学术年会

作者： Bingluo gu zhiyuan Li Xiaona Ma guanghe Liang Institute of Geology and Geophysics The Chinese Academy of Sciences University of Chinese Academy of Sciences Key Laboratory of Mineral Resources Chinese Academy of Sciences

The vector P-and S-seismograms in an elastic common-shot gather generated with a P-wave source in a twodimensional model using a finite difference solution of the P-and S-wave separated velocity–stress equations can be imaged by two independent ERTMs based on the same *** inputs as boundary conditions for reverse-time extrapolation are the pure vector P-and S-waves,*** vector P-wave image components can be obtained by the normalized correlation operation between the vector P-source wavefields and receiver wavefields,which are obtained by extrapolating the vector P-seismograms in reverse-time using the same equations as the forward *** vector S-wave image components can be obtained by a similar *** with the conventional ERTM,this method can minimize the artifacts caused by the crosstalk between different wave modes and can preserve the phase and amplitude attributes of migration images very ***,the polarity-reversal of the vector S-wave data can be corrected automatically during the imaging process,so destructive interferences between data from adjacent sources do not *** examples with synthetic data have demonstrated the feasibility and effectiveness of this method for complex structures.

关键词： Elastic reverse time migration The P-and S-separated elastic equations Crosstalk Polarity-reversal Phase and amplitude attributes

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Agricultural Sciences 2014年第10期5卷 850-857页

作者： Xiaojun Chen Ping Wang zhiyuan Meng Si Chen Haotian gu Xiaoling Sha School of Horticulture and Plant Protection Yangzhou University Yangzhou China

To formulate a scientific basis for a reasonable spray dose and safe interval period of 20% flubendiamide water dispersible granule (WDG) on controlling vegetable pests, degradation dynamics of flubendiamide in cabbage and soil was analyzed in this study. Dissipation and residue of flubendiamide in 20% flubendiamide WDG in cabbage and soil under field conditions were investigated by liquid chromatography-tandem mass spectrometry with dispersive solid phase extraction. Results showed that the degradation dynamic equations of flubendiamide in cabbage and soil were based on the first-order reaction dynamic equations. The half-lives of the degradation of flubendiamide were 3.51 d to 3.96 d and 3.43 d to 3.87 d in the cabbage of Yangzhou and Jingzhou, respectively, and 4.42 d to 5.13 d and 4.37 d to 4.99 d in the soil of Yangzhou and Jingzhou, respectively. The terminal residues of flubendiamide in the cabbage of Yangzhou and Jingzhou were 0.0247 mg·kg-1 to 0.0393 mg·kg-1 and 0.0225 mg·kg-1 to 0.0273 mg·kg-1, respectively, when 20% flubendiamide WDG was applied at a dose of0.050g·m-2. Flubendiamide is safe to be applied in cabbage fields at the recommended dose.

关键词： Flubendiamide Dispersive Solid Phase Extraction LC-MS/MS Degradation Residue

Candidate therapeutic agents in a newly established triple wild-typemucosalmelanoma cell line

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Cancer Communications 2022年第7期42卷 627-647页

作者： Chaoji Shi Ziyue gu Shengming Xu Houyu Ju Yunteng Wu Yong Han Jiayi Li Chuwen Li Jing Wu Lizhen Wang Jiang Li guoyu Zhou Weimin Ye guoxin Ren zhiyuan Zhang Rong Zhou Department of Oral and Maxillofacial-Head Neck Oncology Shanghai Ninth People’s HospitalCollege of StomatologyShanghai Jiao Tong University School of MedicineShanghai 200011P.R.China National Clinical Research Center for Oral Diseases Shanghai 200011P.R.China Shanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology Shanghai 200011P.R.China Research Unit of Oral and Maxillofacial Regenerative Medicine Chinese Academy of Medical SciencesShanghai 200011P.R.China Department of Oral Pathology Ninth People’s HospitalShanghai Jiao Tong UniversitySchool of MedicineShanghai 200011P.R.China

Background:Mucosalmelanoma has characteristically distinct genetic features and typically poor *** lack of representativemucosal melanoma models,especially cell lines,has hindered translational research on this melanoma *** this study,we aimed to establish and provide the biological properties,genomic features and the pharmacological profiles of a mucosal melanoma cell line that would contribute to the understanding and treatment optimization of molecularly-defined mucosal melanoma ***:The sample was collected from a 67-year-old mucosal melanoma patient and processed into pieces for the establishment of cell line and patientderived xenograft(PDX)*** proliferation and tumorigenic property of cancer cells from different passageswere evaluated,andwhole-genome sequencing(WGS)was performed on the original tumor,PDX,established cell line,and the matched blood to confirm the establishment and define the genomic features of this cell *** was conducted to depict the architecture of amplified regions detected by ***-throughput drug screening(HTDS)assay including a total of 103 therapeutic agents was implemented on the established cell line,and selected candidate agents were validated in the corresponding PDX ***:A mucosal melanoma cell line,MM9H-1,was established which exhibited robust proliferation and tumorigenicity after more than 100 serial *** analysis of MM9H-1,corresponding PDX,and the original tumor showed genetic fidelity across genomes,and MM9H-1 was defined as a triple wild-type(TWT)melanoma subtype lacking well-characterized“driver mutations”.Instead,the amplification of several oncogenes,telomerase reverse transcriptase(TERT),v-Rafmurine sarcoma viral oncogene homolog B1(BRAF),melanocyte Inducing transcription factor(MITF)and INO80 complex ATPase subunit(INO80),via large-scale genomic rearrangement potentially contributed to oncogenesis of ***,HTDS identified proteasome

关键词： bortezomib cell line extrachromosomal DNA high-throughput drug screening mucosal melanoma patient derived tumor cells patient-derived xenograft whole-genome sequencing

Associations between cancer family history and esophageal cancer and precancerous lesions in high-risk areas of China

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Chinese Medical Journal 2022年第7期135卷 813-819页

作者： Jiachen Zhou Kexin Sun Shaoming Wang Ru Chen Minjuan Li Jianhua gu zhiyuan Fan guihua Zhuang Wenqiang Wei Department of Epidemiology and Biostatistics School of Public HealthXl’an Jiaotong University Health Science CenterXi’anShaanxi 710061China National Central Cancer Registry National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

Background:Family clustering of esophageal cancer(EC)has been found in high-risk areas of ***,the relationships between cancer family history and esophageal cancer and precancerous lesions(ECPL)have not been comprehensively reported in recent *** study aimed to provide evidence for identification of high-risk ***:This study was conducted in five high-risk areas in China from 2017 to 2019,based on the National Cohort of Esophageal *** permanent residents aged 40 to 69 years were examined by endoscopy,and pathological examination was performed for suspicious *** on demographic characteristics,environmental factors,and cancer family history was *** logistic regression was applied to evaluate odds ratios between family history related factors and ***:Among 33,008 participants,6143(18.61%)reported positive family history of *** proportion of positive family history varied significantly among high-risk *** adjusting for risk factors,participants with a family history of positive cancer,gastric and esophageal cancer or EC had 1.49-fold(95%confidence interval[CI]:1.36-1.62),1.52-fold(95%CI:1.38-1.67),or 1.66-fold(95%CI:1.50-1.84)higher risks of ECPL,*** with single or multiple first-degree relatives(FDR)of positive EC history had 1.65-fold(95%CI:1.47-1.84)or 1.93-fold(95%CI:1.46-2.54)higher risks of *** with FDRs who developed EC before 35,45,and 50 years of age had 4.05-fold(95%CI:1.30-12.65),2.11-fold(95%CI:1.37-3.25),and 1.91-fold(95%CI:1.44-2.54)higher risks of ECPL,***:Participants with positive family history of EC had significantly higher risk of *** risk increased with the number of EC positive FDRs and EC family history of early *** genetic risk factors of the population in high-risk areas of China require further *** registration:ChiCTR-EOC-17010553.

关键词： Esophageal cancer Family history High-risk area Cross-sectional study

Effect of Planting Density on Physiological Indexes, Agronomic Traits and Yield of Buckwheat ( Fagopyrum esculentum Moench.)

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Agricultural Biotechnology 2021年第3期10卷 22-25页

作者： Yaojun CHANG Yangxiu MU Juan gu zhiyuan LU Yanping DU Keqin CHANG Key Laboratory for Meteorological Disaster Monitoring and Early Warning and Risk Management of Characteristic Agriculture in Arid Regions CMABeijing 100081China Ningxia Key Lab of Meteorological Disaster Prevention and Reduction Guyuan 756000China guyuan Branch Ningxia Academy of Agriculture and Forestry SciencesGuyuan 756000China

Ningqiao 1 was selected as the material to study the effects of planting density on physiological indices,agronomic traits and yield of *** results showed that high density resulted in decreases of chlorophyll content,soluble protein content and activity of SOD,POD and CAT,and acceleration of MDA accumulation under drought *** density could effectively improve the grain number per plant,grain weight per plant,1000-grain weight and yield in drought conditions.

关键词： Buckwheat(Fagopyrum esculentum Moench.) Planting density Physiological index Agronomic trait Yield