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Additive manufacturing of thin electrolyte layers via inkjet printing of highly-stable ceramic inks

Journal of Advanced Ceramics 2021年第2期10卷 279-290页

作者： Zhongqi Zhu zhiyuan gong Piao Qu Ziyong Li Sefiu Abolaji Rasaki zhiyuan Liu Pei Wang Changyong Liu Changshi Lao Zhangwei Chen Additive Manufacturing Institute Shenzhen UniversityShenzhen518060China

Inkjet printing is a promising alternative for the fabrication of thin film components for solid oxide fuel cells(SOFCs) due to its contactless, mask free, and controllable printing process. In order to obtain satisfying electrolyte thin layer structures in anode-supported SOFCs, the preparation of suitable electrolyte ceramic inks is a key. At present, such a kind of 8 mol% Y_(2)O_(3)-stabilized ZrO_(2)(8 YSZ) electrolyte ceramic ink with long-term stability and high solid loading(> 15 wt%) seems rare for precise inkjet printing, and a number of characterization and performance aspects of the inks, such as homogeneity, viscosity, and printability, should be studied. In this study, 8 YSZ ceramic inks of varied compositions were developed for inkjet printing of SOFC ceramic electrolyte layers. The dispersing effect of two types of dispersants, i.e., polyacrylic acid ammonium(PAANH4) and polyacrylic acid(PAA), were compared. The results show that ultrasonic dispersion treatment can help effectively disperse the ceramic particles in the inks. PAANH4 has a better dispersion effect for the inks developed in this study. The inks show excellent printable performance in the actual printing process. The stability of the ink can be maintained for a storage period of over 30 days with the help of initial ultrasonic dispersion. Finally, micron-size thin 8 YSZ electrolyte films were successfully fabricated through inkjet printing and sintering, based on the as-developed high solid loading 8 YSZ inks(20 wt%). The films show fully dense and intact structural morphology and smooth interfacial bonding, offering an improved structural quality of electrolyte for enhanced SOFC performance.

关键词： inkjet printing water-based ceramic ink solid oxide fuel cell(SOFC)electrolyte 8YSZ ink stability rheological properties

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Exosome-mediated metabolic reprogramming:the emerging role in tumor microenvironment remodeling and its influence on cancer progression

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Signal Transduction and Targeted Therapy 2020年第1期5卷 421-433页

作者： Enli Yang Xuan Wang zhiyuan gong Miao Yu Haiwei Wu Dongsheng Zhang Department of Oral and Maxillofacial Surgery Shandong Provincial Hospital Affiliated to Shandong First Medical University324 Jingwu Road250021 JinanChina Department of Oral and Maxillofacial Surgery Shandong Provincial Hospital Affiliated to Shandong University324 Jingwu Road250021 JinanChina

Metabolic reprogramming is reported to be one of the hallmarks of cancer,which is an adaptive mechanism by which fast-growing cancer cells adapt to their increasing energy ***,extracellular vesicles(EVs)known as exosomes have been recognized as crucial signaling mediators in regulating the tumor microenvironment(TME).Meanwhile,the TME is a highly heterogeneous ecosystem incorporating cancer cells,fibroblasts,adipocytes,endothelial cells,mesenchymal stem cells,and extracellular *** evidence indicates that exosomes may transfer biologically functional molecules to the recipient cells,which facilitate cancer progression,angiogenesis,metastasis,drug resistance,and immunosuppression by reprogramming the metabolism of cancer cells and their surrounding stromal *** this review,we present the role of exosomes in the TME and the underlying mechanism of how exosomes exacerbate tumor development through metabolic *** addition,we will also discuss the potential role of exosomes targeting metabolic process as biomarkers for tumor diagnosis and prognosis,and exosomes-mediated metabolic reprogramming as potential targets for cancer ***,a better understanding of the link between exosomes and metabolic reprogramming,and their impact on cancer progression,would provide novel insights for cancer prevention and treatment in the future.

关键词： metabolism prevention programming

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Non-destructive detection of tea stalk and insect foreign bodies based on THz-TDS combination of electromagnetic vibration feeder

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Food Quality and Safety 2023年第2期7卷 300-308页

作者： Xudong Sun Chao Xu Chagen Luo Dongfu Xie Wei Fu zhiyuan gong Xinpeng Wang School of Mechatronics and Vehicle Engineering East China Jiaotong UniversityNanchangChina Key Laboratory of Conveyance Equipment(East China Jiaotong University) Ministry of EducationNanchangChina Nanchang Automotive Institute of Intelligence and New Energy(Tongji University) NanchangChina

Background and objectives:Current technology of X-ray imaging can recognize hard foreign materials(FMs)such as metal and high-density ***,low-density foreign bodies are still a challenge for food quality and safety *** and methods:An electromagnetic vibration feeder aided by terahertz time-domain spectroscopy(THz-TDS)and imaging was inves-tigated for non-destructively detecting tea stalk and insect FMs mixed with tea ***:THz time-domain signals were employed directly to develop the K-nearest neighbor model with a precision of 100%,accuracy of 95.6%and recall of 98.7%in predicting the unknown *** contrast THz-TDS images were obtained by the separation method for the samples using electromagnetic vibration *** characteristic parameters of the ratio of maximum length(L)to maximum width(W)and hue extracted from THz-TDS images indicated significant difference between tea leaves and ***:The results suggested that electromagnetic vibration feeder combination with THz-TDS was feasible for detecting FMs in fin-ishingteaproducts.

关键词： Terahertz spectroscopy imaging food foreign bodies

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Molecular insights of organochlorine biocide-induced toxicity in zebrafish:Whole-adult-organism toxicogenomics,targeted gene expression and histological analyses

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Journal of Genetics and Genomics 2016年第8期43卷 525-528页

作者： eei yin lui caixia li zhi-hua li zhiyuan gong siew hong lam nus environmental research institute national university of singapore117411Singapore department of biological sciences national university of singapore117543Singapore yangtze river fisheries research institute chinese academy of fishery sciencesWuhan 430223China

Organochlorine biocides （OCBs）, such as lindane and dichlorodi- phenyltrichloroethane （DDT）, have been used for control of vector- borne diseases in public health and for insect pest control in agri- culture. These chemicals are extremely persistent in the environ- ment and they tend to bioaccumulate via food chains, thus posing risk to human and ecological health （Cooney et al., 2010; Wang et al., 2013）. Due to their persistence in the environment and continuous use in certain countries despite the banning of some of these chemicals, monitoring and studies of OCBs have continued intensely and remain relevant in foreseeable future （ Cohn et al.,

关键词： Molecular insights of organochlorine biocide-induced toxicity in zebrafish gene

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Analysis of nucleosome positioning in promoters of miRNA genes and protein-coding genes

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Chinese Science Bulletin 2010年第22期55卷 2347-2352页

作者： LIU HongDe ZHANG DeJin XIE JianMing YUAN ZhiDong MA Xin LU zhiyuan gong LeJun SUN Xiao State Key Laboratory of Bioelectronics Southeast University Nanjing 210096 China

Nucleosome positioning in promoters is important for gene transcription regulation. In this paper, with a nucleosome prediction model, curvature profile, the characteristics of nucleosome positioning in promoters are analyzed for miRNA genes and protein-coding genes. In the vicinity of transcription start site (TSS), there is a nucleosome-free region (NFR) followed by a positioned nucleosome at ～200 bp downstream of TSS. A similar characteristic is observed in independent intronic promoters and intergenic promoters, namely, both types of promoters have a longer NFR in 0—-400 bp upstream of TSS. Moreover, transcription factor binding sites (TFBSs) locate in the NFR with a high concentration. However, nucleosome pattern in dependent intronic promoters are like that in protein-coding promoters, with two nucleosomes positioned at -200—-400 bp and -400—-600 bp upstream of TSS. The results indicate nucleosome positioning is probably different in independent miRNA promoters and protein-coding promoters; and positioning seems to be an important factor not only in regulation of protein-coding gene, but also in that of miRNA gene.

关键词：蛋白编码基因基因启动子核小体点定位 RNA基因 miRNA 蛋白质编码转录起始位点

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铁谱图像分析方法中数据处理及实现

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润滑与密封 2005年第3期30卷 91-93页

作者：龚志远华东交通大学江西南昌330013

论述了磨粒在铁谱仪磁场下的分布状态及规律,构建了图像分析的数学模型,求解了磨粒分布函数,利用VB编程实现数据的处理,作图直观描述出磨粒的分布,提出了铁谱分析的一种新方法。

关键词：图像分析方法数据处理分布状态数学模型分布函数 VB编程铁谱分析铁谱仪磨粒作图

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铁谱图像分析技术研究

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润滑与密封 2006年第8期31卷 106-108,111页

作者：龚志远华东交通大学江西南昌330013

利用MATLAB的图像处理技术对铁谱磨粒图像进行数字化分析,求解了磨粒图谱的一些形状特征参数,通过对量化的数据进行统计和比较,揭示了铁谱图像的一些基本特性,以及这些特征所代表的一般意义和在铁谱磨粒图像分析过程中应用。同时,提出... 详细信息

利用MATLAB的图像处理技术对铁谱磨粒图像进行数字化分析,求解了磨粒图谱的一些形状特征参数,通过对量化的数据进行统计和比较,揭示了铁谱图像的一些基本特性,以及这些特征所代表的一般意义和在铁谱磨粒图像分析过程中应用。同时,提出了铁谱图像进行计算机图像处理的一般过程以及常用的处理方法。

关键词：磨粒形状特征参数图像处理 MATLAB

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Genetically engineered bacterial-like particles induced specific cellular and humoral immunity as effective tick-borne encephalitis virus vaccine

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Aggregate 2023年第3期4卷 175-183页

作者： Mengyao Zhang Hongli Jin Yuanyuan Li Cuicui Jiao Pei Huang Yujie Bai zhiyuan gong Haili Zhang Shunjie Liu Hualei Wang Key Laboratory of Zoonosis Research Ministry of EducationCollege of Veterinary MedicineJilin UniversityChangchunChina

Tick-borne encephalitis(TBE)is a natural focal disease with fatal encephalitis induced by tick-borne encephalitis virus(TBEV),seriously threatening human and public *** of TBE depends on vaccination with inactivated vaccine,which requires high cost and multiple ***,we construct genetically engineered bacterial-like particles(BLPs)as an effective TBEV vaccine with simplified immunizations and improved immune *** TBEV BLPs involve the combination of the gram-positive enhancer matrix from Lactococcus lactis,and TBEV envelope(E)protein expressed by genetically engineered recombinant *** prepared TBEV BLPs can effectively stimulate the activation of dendritic cells to present the TBEV E proteins to T and B cells,leading to strong and durable cellular and humoral immune responses in ***,the serum levels of specific IgG antibodies in mice remain about 10^(6)at 6 months after the secondary ***,the TBEV BLPs can be used as a potent vaccine candidate,laying the foundation for developing novel TBEV genetically engineered vaccines.

关键词： bacterial-like particles envelope protein genetically engineered vaccines gram-positive enhancer matrix tick-borne encephalitis virus

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微型自动化立体仓库设计

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制造技术与机床 2011年第8期 79-82页

作者：龚志远华东交通大学江西南昌330013

微型立体仓库是面向高校机械及自动化专业的经济型实验装置,其机械系统可实现对9个货位物料的存取,控制系统实现对装置的逻辑控制。根据物料重量及加减速初始条件,计算X、Y、Z三个方向分力及折算转矩,选择直流电动机和轴承,设计丝杠螺... 详细信息

微型立体仓库是面向高校机械及自动化专业的经济型实验装置,其机械系统可实现对9个货位物料的存取,控制系统实现对装置的逻辑控制。根据物料重量及加减速初始条件,计算X、Y、Z三个方向分力及折算转矩,选择直流电动机和轴承,设计丝杠螺母副、导轨和机体,完成机械系统的设计;根据3台直流电动机的动作逻辑和硬件I/O配置,完成接口电路系统的设计。上位机使用VB的MSComm控件,编写FX2N-PLC通信协议代码,实现上下位机的串行通信,完成显示货位号、寻货、取货、存货、急停、回零等动作的控制。

关键词：微型立体仓库机械系统设计 PLC 接口电路设计 VB

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基于模型的立体仓库CC-Link总线控制系统

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机床与液压 2013年第11期41卷 108-111页

作者：龚志远华东交通大学江西南昌330013

针对三排九仓位立体仓库模型,构建了由FX2N-PLC作为主站和从站的现场总线结构,介绍本地站单排立体仓库控制方法,详细分析了CC-Link对3个本地站总线信号传输原理、工作方式和技术要点,对各站对应的缓存地址进行了分配,阐明了数据链接的... 详细信息

针对三排九仓位立体仓库模型,构建了由FX2N-PLC作为主站和从站的现场总线结构,介绍本地站单排立体仓库控制方法,详细分析了CC-Link对3个本地站总线信号传输原理、工作方式和技术要点,对各站对应的缓存地址进行了分配,阐明了数据链接的的关键要点,通过举例给出了数据传输格式以及数据链接的关键程序。系统根据PC机的指令,由主站PLC在总线上下发数据链接信号,自动控制立体仓库存取货物。

关键词： CC-Link 总线结构数据链接编程方法

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