检索结果-南通市图书馆

World Journal of Gastrointestinal Oncology 2024年第6期16卷 2362-2379页

作者： Yi Zhou Shuang Wu Fan-Jie qu Department of Oncology Affiliated Dalian Third People’s Hospital of Dalian Medical UniversityDalian 116033Liaoning ProvinceChina

More than 1.9 million new colorectal cancer(CRC)cases and 935000 deaths were estimated to occur worldwide in 2020,representing about one in ten cancer cases and ***,colorectal ranks third in incidence,but second in *** than half of the patients are in advanced stages at *** options are complex because of the heterogeneity of the patient population,including different molecular *** have included conventional fluorouracil-based chemotherapy,targeted therapy,immunotherapy,*** recent years,with the development of genetic testing technology,more and more targeted drugs have been applied to the treatment of CRC,which has further prolonged the survival of metastatic CRC patients.

关键词： Metastatic colorectal cancer Epidermal growth factor receptor B-type RAF mutation Kirsten rat sarcoma viral oncogene wild type Kirsten rat sarcoma viral oncogene G12C mutation Human epidermal growth factor receptor 2 overexpression/amplification

Proper interpretation of sectional analysis results

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Earthquake Research Advances 2024年第2期4卷 65-71页

作者： Juyuan Zheng Yuli Huang Zhe qu Key Laboratory of Earthquake Engineering and Engineering Vibration Institute of Engineering MechanicsChina Earthquake AdministrationHarbin150080China Key Laboratory of Earthquake Disaster Mitigation Ministry of Emergency ManagementHarbin150080China Arup 560 Mission StreetSuite 700San FranciscoCA94105United States

Displacement control algorithms commonly used to evaluate axial force-bending moment(PM)diagrams may lead to incorrect interpretations of the strength envelopes for asymmetric *** paper aims to offer valuable insights by comparing existing displacement control algorithms with a newly proposed force control *** main focus is on the PM diagrams of three example sections that exhibit varying degrees of *** comparative study indicates that conventional displacement control algorithms inevitably introduce non-zero out-of-plane bending *** reported PM diagram in such cases erroneously neglects the out-of-plane moment and fails to represent the strength envelope *** oversight results in significant and unconservative errors when verifying the strength of asymmetric sections.

关键词： Fiber section model Axial force-moment interaction diagram Limit state Failure surface

Experimental study on workability and permeability of sandy soils conditioned with thickened foam

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2024年第2期16卷 532-544页

作者： Zhiyao Feng Shuying Wang Tongming qu Xiangcou Zheng Fanlin Ling School of Civil Engineering Central South UniversityChangsha410075China Tunnel and Underground Engineering Research Center Central South UniversityChangsha410075China Department of Civil and Environmental Engineering The Hong Kong University of Science and TechnologyClearwater BayKowloon999077Hong KongChina Geo-Engineering Section Delft University of TechnologyDelft999025Netherlands

Water spewing and muck plugging often occur during earth pressure balance(EPB)shield machines tunnelling in water-rich sandy strata,even though the conventional foam has been employed to condition sandy *** this study,a novel thickened foaming agent suitable for EPB shield tunnelling in water-rich sandy strata is *** contrast to conventional foam-conditioned sands,the thickened foam-conditioned sand has a low permeability due to the consistent filling of soil pores with the thickened foam,and the initial permeability coefficient decreases by approximately two orders of *** also exhibits a suitable workability,which is attributed to the enhanced capability of the thickened foam to condition sandy *** addition,the effect of concentration on the stability of the foam is explained by the Gibbs-Marangoni effect,and conditioning mechanisms for the thickened foam on sands are discussed from the evolution of foam bubbles.

关键词： Earth pressure balance(EPB)shield Thickened foam Foam-conditioned sand Permeability Workability

Power Generation Enhancement in a Solar Energy and Biomass-Based Distributed Energy System using H_(2)O/CO_(2)Hybrid Gasification

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2024年第5期33卷 1657-1671页

作者： WU Haifeng LYU Yan WANG Ruixiang XU Rongji qu Wanjun LIU Qibin Beijing Engineering Research Center of Sustainable Energy and Buildings Beijing University of Civil Engineering and ArchitectureBeijing 100044China Guangdong Provincial Key Laboratory of Distributed Energy Systems School of Chemical Engineering and Energy TechnologyDongguan University of TechnologyDongguan 523808China Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing 100190China

A new solar energy and biomass-based distributed energy system using H_(2)O/CO_(2)hybrid gasification is proposed,and their complementarity to enhance the system's energy efficiency is investigated and *** the system,concentrated solar energy is used to provide heat for biomass gasification;two gasifying agents(H_(2)O and CO_(2))are adopted to enhance syngas yields,and the produced solar fuel is further burned for power production in a combined cycle *** show that CO share in gasification products is remarkably increased with the increment of CO_(2)/H_(2)O mole ratio caused by the boudouard reaction with the consumption of fixed carbon,while the H_(2)share is decreased;the optimal solar-to-fuel efficiency,27.88%,is achieved when the temperature and CO_(2)/H_(2)O mole ratio are 1050℃and 0.45,*** emission reduction rate of CO_(2)in the system under design conditions is reduced by 2.31%compared with that using only H_(2)O *** annual power production of the system is increased by 1.39%,and the thermodynamic and environmental performances are significantly ***,an economic assessment is conducted to forecast the technical feasibility of the hybrid gasification *** work provides a promising route to improving the thermochemical utilization efficiency of solar energy and solid fuel.

关键词： solar energy biomass hybrid gasification distributed energy system thermodynamics performance

A scalable one-pot strategy for the development of polymer electrolytes adaptable to room-temperature high-voltage lithium batteries

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第3期35卷 461-467页

作者： Yue Guo Xinxin qu Zhen Li Ruiyuan Tian Xiaokong Liu State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012China Key Laboratory of Physics and Technology for Advanced Batteries(Ministry of Education) College of PhysicsJilin UniversityChangchun 130012China

Poly(ethylene oxide)(PEO)polymer electrolytes(PEs)have been commercially applied in LiFePO_(4)||Li solid-state lithium batteries(SSLBs).However,it remains challenging to develop PEO-based PEs applicable to the high-voltage SSLBs with higher energy density,owing to the poor electrochemical stability of ***,we report a scalable strategy for fabricating PEO-based PEs with high-voltage compatibility,by exploiting a new mechanism to stabilize the cathode-electrolyte interface in the highvoltage *** protocol only involves a one-pot synthesis procedure to covalently crosslink the PEO chains,in the presence of high-content lithium bis(trifluoromethylsulphonyl)imide(LiTFSI)salts and N,N-dimethylformamide(DMF).LiTFSI-DMF supramolecular aggregates are formed and firmly embedded in the polymer network,endowing the PE with high room-temperature ionic *** dissociated and highly concentrated TFSI^-anions can enter the Helmholtz layer close to the high-voltage cathode,leading to the formation of a thin and homogeneous cathode electrolyte interface(CEI),mainly composed of LiF,on the *** CEI with high electrochemical stability can effectively stabilize the cathode-electrolyte interface,enabling long-term stable cycling of the high-voltage LiCoO_(2)||Li and nickelrich NCM_(622)||Li batteries at room *** simplicity and scalability of the strategy makes the reported PEO-based PE potentially applicable in high-voltage SSLBs in practice.

关键词： Lithium batteries Polymer electrolytes Poly(ethylene oxide) Energy density High-voltage cathodes

Nickel-Catalyzed Regiodivergent Acylzincation of Styrenes with Organozincs and CO

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2024年第6期42卷 599-604页

作者： Chenglong Wang Ning Liu Xianqing Wu Jingping qu Yifeng Chen Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering Feringa Nobel Prize Scientist Joint Research CenterFrontiers Science Center for Materiobiology and Dynamic ChemistrySchool of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai200237 China Dedicated to the Special Issue of C1 Chemistry.

Transition metal-catalyzed carbometallation of unsaturated hydrocarbons constitutes one of the most efficient synthetic methodologies for the construction of C—C ***,the incorporation of organometallic reagent with the CO gas as a nucleophilic acyl synthon could enable the acylmetallation reaction,which greatly increases the horizon of carbometallation ***,we report a nickel-catalyzed regiodivergent acylzincation of o-cyano cinnamate ester and o-cyano styrene,in which the cyano moiety intramolecularly captures zinc intermediates to trigger the tandem cyclization *** protocol features mild conditions,broad substrate scope and excellent functional group tolerance,thus affording a diverse array of highly functionalized carbocyclic compounds.

关键词： Carbonylation Carbometallation Styrene Nickel Cyclization

A refined deviatoric hardening plastic model for sand

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2024年第7期16卷 2813-2821页

作者： Min Wang Tongming qu Yuntian Feng Teng Liang Liangtong Zhan MOE Key Laboratory of Soft Soils and Geoenvironmental Engineering Zhejiang UniversityHangzhou310058China Department of Civil and Environmental Engineering Hong Kong University of Science and TechnologyKowloon999077Hong KongChina Zienkiewicz Centre for Computational Engineering College of EngineeringSwansea UniversitySwanseaWalesSA18EPUK Center for Hypergravity Experimental and Interdisciplinary Research Zhejiang UniversityHangzhou310058China

The classical deviatoric hardening models are capable of characterizing the mechanical response of granular materials for a broad range of degrees of *** work finds that it has limitations in accurately predicting the volumetric deformation characteristics under a wide range of confining/consolidation *** issue stems from the pressure independent hardening law in the classical deviatoric hardening *** overcome this problem,we propose a refined deviatoric hardening model in which a pressure-dependent hardening law is developed based on experimental *** between numerical results and laboratory triaxial tests indicate that the improved model succeeds in capturing the volumetric deformation behavior under various confining/consolidation pressure conditions for both dense and loose ***,to examine the importance of the improved deviatoric hardening model,it is combined with the bounding surface plasticity theory to investigate the mechanical response of loose sand under complex cyclic loadings and different initial consolidation *** is proved that the proposed pressure-dependent deviatoric hardening law is capable of predicting the volumetric deformation characteristics to a satisfactory degree and plays an important role in the simulation of complex deformations for granular geomaterials.

关键词： Elasto-plastic deformation Isotropic hardening Deviatoric plastic strain Granular material Kinematic hardening Bounding surface

Doubled haploid technology and synthetic apomixis:Recent advances and applications in future crop breeding

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2024年第7期17卷 1005-1018页

作者： Yanzhi qu Alisdair R.Fernie Jie Liu Jianbing Yan National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070China Hubei Hongshan Laboratory Wuhan 430070China Department of Molecular Physiology Max-Planck-Institute of Molecular Plant Physiology14476 Potsdam-GolmGermany Center of Plant Systems Biology and Biotechnology 4000 PlovdivBulgaria azhouwan National Laboratory Sanya 572024China

Doubled haploid(DH)technology and synthetic apomixis approaches can considerably shorten breeding cycles and enhance breeding *** with traditional breeding methods,DH technology offers the advantage of rapidly generating inbred lines,while synthetic apomixis can effectively fix hybrid *** this review,we focus on(i)recent advances in identifying and characterizing genes responsible for haploid induction(Hl),(ii)the molecular mechanisms of Hl,(ili)spontaneous haploid genome doubling,and(iv)crop synthetic *** also discuss the challenges and potential solutions for future crop breeding programs utilizing DH technology and synthetic ***,we provide our perspectives about how to integrate DH and synthetic apomixis for precision breeding and de novo domestication.

关键词： maize doubled haploid technology haploid induction synthetic apomixis precision breeding

Effects of long-term fencing on soil microbial community structure and function in the desert steppe,China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Arid Land 2024年第3期16卷 431-446页

作者： PAN Yaqing KANG Peng qu Xuan RAN Yichao LI Xinrong Shapotou Desert Research and Experiment Station Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China School of Biological Science and Engineering North Minzu UniversityYinchuan 750021China

One of the goals of grazing management in the desert steppe is to improve its ***,relatively little is known about soil microbe communities in the desert steppe ecosystem under grazing *** this study,we investigated the diversity and aboveground biomass of Caragana korshinskii *** communities in long-term fencing and grazing areas,combined with an analysis of soil physical-chemical properties and genomics,with the aim of understanding how fence management affects plant-soil-microbial inter-relationships in the desert steppe,*** results showed that fence management(exclosure)increased plant diversity and aboveground biomass in *** shrub area and effectively enhanced soil organic carbon(233.94%),available nitrogen(87.77%),and available phosphorus(53.67%)*** well,the Shannon indices of soil bacteria and fungi were greater in the fenced ***-soil changes profoundly affected the alpha-and beta-diversity of soil *** management also altered the soil microbial community structure,significantly increasing the relative abundances of Acidobacteriota(5.31%-8.99%),Chloroflexi(3.99%-5.58%),and Glomeromycota(1.37%-3.28%).The soil bacterial-fungal co-occurrence networks under fence management had higher complexity and *** on functional predictions,fence management significantly increased the relative abundance of bacteria with nitrification and nitrate reduction functions and decreased the relative abundance of bacteria with nitrate and nitrite respiration *** relative abundances of ecologically functional fungi with arbuscular mycorrhizal fungi,ectomycorrhizal fungi,and saprotrophs also significantly increased under fence *** addition,the differential functional groups of bacteria and fungi were closely related to plant-soil *** results of this study have significant positive implications for the ecological restoration and reconstruction of dry desert steppe and simila

关键词： desert steppe fence management Caragana korshinskii soil physical-chemical property soil microorganism

Complex transmission matrix retrieval for a highly scattering medium via regional phase differentiation

在线全文

学校读者我要写书评

暂无评论

Photonics Research 2024年第5期12卷 876-883页

作者： QIAOZHI HE RONGJUN SHAO YUAN qu LINXIAN LIU CHUNXU DING JIAMIAO YANG School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China Institute of Marine Equipment Shanghai Jiao Tong UniversityShanghai 200240China School of Automation and Software Engineering Shanxi UniversityTaiyuan 030006China

Accurately measuring the complex transmission matrix(CTM) of the scattering medium(SM) holds critical significance for applications in anti-scattering optical imaging, phototherapy, and optical neural networks. Noninterferometric approaches, utilizing phase retrieval algorithms, can robustly extract the CTM from the speckle patterns formed by multiple probing fields traversing the SM. However, in cases where an amplitude-type spatial light modulator is employed for probing field modulation, the absence of phase control frequently results in the convergence towards a local optimum, undermining the measurement accuracy. Here, we propose a high-accuracy CTM retrieval(CTMR) approach based on regional phase differentiation(RPD). It incorporates a sequence of additional phase masks into the probing fields, imposing a priori constraints on the phase retrieval algorithms. By distinguishing the variance of speckle patterns produced by different phase masks, the RPD-CTMR can effectively direct the algorithm towards a solution that closely approximates the CTM of the SM. We built a prototype of a digital micromirror device modulated RPD-CTMR. By accurately measuring the CTM of diffusers, we achieved an enhancement in the peak-to-background ratio of anti-scattering focusing by a factor of 3.6, alongside a reduction in the bit error rate of anti-scattering image transmission by a factor of 24. Our proposed approach aims to facilitate precise modulation of scattered optical fields, thereby fostering advancements in diverse fields including high-resolution microscopy, biomedical optical imaging, and optical communications.

关键词： matrix phase holds

同方期刊数据库