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SH波入射下山体-断层破碎带-隧道相互作用分析

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防灾减灾工程学报 2024年第4期44卷 870-880页

作者：黄磊周颜婷刘中宪段更月张传秀天津城建大学土木工程学院天津300384 天津市软土特性与工程环境重点实验室天津300384 北京智宇天成设计咨询有限公司北京100000

采用一种高精度间接边界积分方程法(IBIEM),开展了山体-断层破碎带-隧道整体模型对地震波的散射作用模拟,考虑了三种影响因素:入射波强度、隧道与断层破碎带间距以及破碎带动力特性,模拟了其对山体表面及隧道地震动力响应的影响。研究... 详细信息

采用一种高精度间接边界积分方程法(IBIEM),开展了山体-断层破碎带-隧道整体模型对地震波的散射作用模拟,考虑了三种影响因素:入射波强度、隧道与断层破碎带间距以及破碎带动力特性,模拟了其对山体表面及隧道地震动力响应的影响。研究结果表明:断层破碎带的存在使得山体-断层破碎带-隧道整体系统内相互作用更加复杂,山体表面位移幅值以及隧道的位移和应力幅值主要呈现放大效应,山体表面断层破裂处破坏异常严重,位移幅值陡增,可达10以上;在衬砌的拱肩、拱脚处的应力集中较为明显,衬砌的顶部和底部应力较小;地震波低频入射时,隧道内外壁应力和位移曲线较平缓,随着入射频率的增大,波的相干效应更加明显,衬砌隧道应力和位移发生空间重分布,出现峰值多段集中现象。

关键词：山体断层破碎带隧道地震波散射

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基于VLAN技术的电子式互感器数字接口

电工技术学报 2008年第3期23卷 36-40页

作者：黄智宇段雄英邹圆张春鹏大连理工大学电气工程与应用电子技术系大连116024

电子式互感器数字接口使用常规以太网组播/广播模式进行通信,存在载波冲突、网络负载过重和广播风暴等问题。在分析了电子式互感器数字通信和VLAN技术特点的基础上,对变电站网络建设和电子式互感器数字传输帧做了一定的改进,并设计了一... 详细信息

电子式互感器数字接口使用常规以太网组播/广播模式进行通信,存在载波冲突、网络负载过重和广播风暴等问题。在分析了电子式互感器数字通信和VLAN技术特点的基础上,对变电站网络建设和电子式互感器数字传输帧做了一定的改进,并设计了一套基于VLAN技术的电子式互感器数字接口,使其利于互感器与二次设备利用组播/广播模式进行实时数据传输,从而提高了电子式互感器和二次设备之间通信的实时性和可靠性。

关键词：电子式互感器 VLAN技术数字接口 IEC(标准)61850

木霉LE02 β-1，3-葡聚糖酶酶学特性的研究

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食品与发酵工业 2007年第5期33卷 32-36页

作者：唐治玉段会轲熊善柏华中农业大学食品科技学院

对木霉菌株LE02所产β-1,3-葡聚糖酶的酶学特性进行了研究。结果表明,该酶最适反应温度为55℃、最适反应pH值为5.0。Co^(2+)、K+、Zn^(2+)、Li^+、Ba^(2+)、Cu^(2+)以及1.0mmol/L的Fe^(2+)对该酶没有影响,Cd^(2+)和10.0mmol/L的Mg^(2+)对酶具有部分抑制作用,而低浓度的Hg^(2+)、5.0mmol/L以上的Mn^(2+)和10.0 mmol/L的Fe^(3+)能强烈抑制该酶的活性。该酶只能作用于β-1,3-糖苷键,以Larinami为底物时其米氏常数K_m值为128.34μg/mL,最大反应速度V_m为23.01μg/(min·mL)。经过SDS-PAGE测定的分子质量近似为80.137ku。

关键词：木霉LE02 β-1 3-葡聚糖酶酶学特性

26型/246型氟橡胶多段硫化机理及结构与性能

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材料导报 2021年第12期35卷 12202-12208页

作者：李东翰段佳玉张超徐志宇方庆红沈阳化工大学材料科学与工程学院沈阳110142 沈阳化工大学辽宁省橡胶弹性体重点实验室沈阳110142

选用2601氟橡胶(2601FKM)和2461氟橡胶(2461FKM)为原料,N,N′-双亚肉桂基-1,6-己二胺为硫化剂,制备了加工性能优异、强度适中、低温性能好的氟橡胶共混胶。采用氟谱固体核磁(^(19)F MAS-NMR)、红外光谱(ATR-FTIR)分析了2601FKM、2461FK... 详细信息

选用2601氟橡胶(2601FKM)和2461氟橡胶(2461FKM)为原料,N,N′-双亚肉桂基-1,6-己二胺为硫化剂,制备了加工性能优异、强度适中、低温性能好的氟橡胶共混胶。采用氟谱固体核磁(^(19)F MAS-NMR)、红外光谱(ATR-FTIR)分析了2601FKM、2461FKM及其共混胶多段硫化过程中链结构的演变,提出了该共混胶的多段硫化机理。进一步地,对共混胶的硫化特性和交联密度进行了测试分析,并采用差式扫描量热仪(DSC)、热重分析仪(TGA)和拉伸试验对比了一段硫化和二段硫化产物的热性能和拉伸性能。结果表明,2601FKM和2461FKM二段硫化产物交联键含量均高于一段硫化,2461FKM二段硫化产物的交联键含量是2601FKM的1.67倍;当2601FKM/2461FKM共混比为40/60时,硫化产物的玻璃化转变温度(T_(g))均较低,一段硫化产物的T_(g)为-16.5℃,二段硫化产物的T_(g)为-12.1℃,耐低温性良好;随着共混胶中2461FKM用量的增加,两段硫化产物的热分解温度(T_(d))均明显升高;随着共混胶中2461FKM用量的增加,其拉伸强度线性增加。

关键词：氟橡胶多段硫化硫化机理

Marker Technique and its Application in the Source Address Recognition Research

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Marker Technique and its Application in the Source Address R...

Aripiprazole in the treatment of acute episode of schizophrenia: a real-world study in China

2012 National Conference on Information Technology and Computer Science

作者： Zhu zhiyu Network Information Center Changsha University,Hunan,China duan Huiliang Network Information Center Central South University of Forestry and Technology Hunan,China

SPi is an end system of validation technique,in which routers mark packets,and end system performs *** construct the simulation with various network topologies to verify the effectiveness and the filtering accuracy of the SVA *** simulation results show that,SVA can respond quickly to the source address forgery attack,and has a better filtration.

关键词： source address validation SPi SVA

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Chinese Medical Journal 2023年第9期136卷 1126-1128页

作者： Qian Li Yun’ai Su Xuemei Liao Maosheng Fang Jianliang Gao Jia Xu Mingjun duan Haiying Yu Yang Yang zhiyu Chen Jintong Liu Shaoxiao Yan Peifen Yao Shuying Li Changhong Wang Bin Wu Congpei Zhang Tianmei Si Department of Psychopharmacology Peking University Sixth Hospital(Institute of Mental Health)NHC Key Laboratory of Mental Health(Peking University)National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital)Beijing 100191China Department of Psychiatry Wuhan Mental Health CenterWuhanHubei 430012China Department of Child and Adolescent Psychology the Fourth People’s Hospital of HefeiHefeiAnhui 230022China Mental Health Center the First Psychiatric Hospital of HarbinHarbinHeilongjiang 150056China Department of Science and Education the Fourth People’s Hospital of ChengduChengduSichuan 610036China Department of Psychiatry the Chinese People’s Liberation Army 904th HospitalChangzhouJiangsu 213003China Department of Psychiatry Beijing Anding HospitalBeijing 100029China Department of Psychiatry Hangzhou Seventh People’s HospitalHangzhouZhejiang 310063China Department of Adolescent and Child Psychological Behavior Shandong Mental Health CenterJinanShandong 250014China Department of Integrated Chinese and Western Medicine Beijing Huilongguan HospitalBeijing 102208China Department of Psychiatry Shanghai Mental Health CenterShanghai 201109China Department of Psychiatry the First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Department of Psychiatry the Second Affiliated Hospital of Xinxiang Medical UniversityXinxiangHenan 456750China Department of Psychiatry Xi’an Mental Health CenterXi’anShaanxi 710067China

To the Editor:Schizophrenia is a progressive,debilitating disease.[1]Safe and effective treatment performed during the acute phase is the first step to improve prognosis,and it is critically *** is known as a dopamine system stabilizer,and it exerts partial agonism with high affinity at dopamine D2 and serotonin-1A(5-HT1A)receptors as well as antagonism at serotonin-2A(5-HT2A)receptors.[2]It has been shown to be efficacious in amelioration of both positive and negative symptoms of acute schizophrenia,and it shows better tolerance than most antipsychotics.[3]We conducted a real-world study to further confirm the efficacy and safety of aripiprazole in patients with acute episodes of schizophrenia in China and tried to explore the clinical variables,including various drug regimens,which may be correlated with the efficacy of aripiprazole,and provide a basis for the optimization of aripiprazole treatment for patients with acute schizophrenia.

关键词： schizophrenia acute dopamine

SND1 promotes cholesterol synthesis and ameliorates high fat diet-induced hepatic steatosis and insulin resistance in mice

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SND1 promotes cholesterol synthesis and ameliorates high fat...

第十一届全国免疫学学术大会

作者： Wang Xinting Lingbiao Xin Zhongchao duan zhiyu Zuo Ruanruan Ren Xin Liu Lin Ge Silvennoinen Olli Minxin Wei Zhi Yao Xi Yang Jie Yang Tianjin Medical University University of Tampere Tianjin Medical University General Hospital University of Manitoba

Aim: Staphylococcal nuclease domain containing 1(SND1) transcriptionally activates adipogenesis and regulates adipocyte differentiation, but its contribution to the metabolic homeostasis in vivo is unclear. The current study aimed to explore impact of SND1 overexpression in vivo on high-fat diet-induced(HFD) nonalcoholic fatty liver disease(NAFLD).Method: Wild-type and globally expressed SND1 transgenic mice on C57BL/6 were fed a high-fat diet for 12 ***: Compared to wild-type mice, the HFD in transgenic mice induced lower liver and body weight as well as decreased hepatic steatosis and elevated hepatic cholesterol and LDL-cholesterol in the blood. Microarray profiling on HFD-liver revealed a series of genes involved in hepatic cholesterol biosynthesis were increased, which was associated with activation of sterol regulatory element-binding protein 2(SREBP2) through SREBP cleavage-activating protein(SCAP). In human hepatoma cells, chromatin immunoprecipitation assay revealed the binding of SND1 to the Scap promoter, and transient transfection with full length SND1 activated a Scap promoter-reporter in response to free fatty acids or TNFa, identifying Scap as a SND1 direct transcriptional target. Biopsy studies from NAFLD patients confirmed a significant correlation between SND1 and Scap mR NA expression in human liver tissues. Inflammation experiments showed an elevated inflammatory state in HFD-Tg liver with increased Tnfa expression. More importantly, HFD-transgenic mice show increased level of circulating leptin derived from larger white adipose mass characterized by active de novo lipogenesis in fat. Moreover, SND1 transgenic mice in high fat diet protected from insulin resistance, central to NAFLD pathogenesis, evidenced by increased insulin sensitivity both in mice liver and primary ***: SND1 regulates cholesterol metabolism and improve liver steatosis and insulin resistance in nonalcoholic fatty liver disease.

关键词： NAFLD SREBP SCAP leptin insulin resistance phospholipids cholesterols

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泵喷推进航行体有动力流场数值仿真

弹箭与制导学报 2012年第3期32卷 161-163,170页

作者：段相杰董永香冯顺山邵志宇北京理工大学爆炸科学与技术国家重点实验室北京100081

为实现对泵喷推进航行体有动力流场的数值模拟,基于多参考系模型(MRF)建立了有动力流场模型;利用Fluent软件求解以k-εRNG湍流模型封闭的RANS方程实现流场的数值仿真;在用试验数据对仿真结果验证基础上,分析了泵喷推进器对航行体水动力... 详细信息

为实现对泵喷推进航行体有动力流场的数值模拟,基于多参考系模型(MRF)建立了有动力流场模型;利用Fluent软件求解以k-εRNG湍流模型封闭的RANS方程实现流场的数值仿真;在用试验数据对仿真结果验证基础上,分析了泵喷推进器对航行体水动力参数的影响规律,结果表明文中所研究的泵喷推进器使航行体在10m/s航速下的阻力系数增大约47%,对垂向力系数和俯仰力矩系数影响小于3%。所建立的数值仿真方法及结果可为航行体水动力特性研究提供重要参考。

关键词：泵喷推进器有动力流场水动力特性 MRF

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氧化石墨烯对发泡水泥结构和性能的影响

非金属矿 2020年第3期43卷 26-29页

作者：王之宇李春段毓敏郭家林商洛学院陕西省尾矿资源综合利用重点实验室陕西商洛726000 商洛学院化学工程与现代材料学院陕西商洛726000

为提高水泥/尾矿基发泡水泥保温板的力学性能,解决制约其推广应用的瓶颈问题,将氧化石墨烯作为添加剂加入发泡水泥原料中进行试验,对氧化石墨烯掺量与发泡水泥性能之间的关系及作用机理进行研究分析。在成熟配比的基础上添加不同质量分... 详细信息

为提高水泥/尾矿基发泡水泥保温板的力学性能,解决制约其推广应用的瓶颈问题,将氧化石墨烯作为添加剂加入发泡水泥原料中进行试验,对氧化石墨烯掺量与发泡水泥性能之间的关系及作用机理进行研究分析。在成熟配比的基础上添加不同质量分数的氧化石墨烯,通过测试试件抗压强度、抗折强度、泡孔结构等方法,确定最佳氧化石墨烯掺量,并结合扫描电镜(SEM)分析氧化石墨烯对发泡水泥微观形貌的影响及作用机理。结果表明,原料中掺入氧化石墨烯可以提高发泡水泥保温板的抗压强度和抗折强度,可以优化发泡水泥保温板的泡孔形态,氧化石墨烯对发泡水泥水化产物的形成具有模板效应和填充效应。水泥/尾矿基发泡水泥保温板原料中石墨烯最佳掺入量为0.02%。

关键词：氧化石墨烯尾矿发泡水泥泡孔结构力学性能