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家蚕淡红卵突变体(rep-1)的发现及卵色相关基因MFS的结构分析

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蚕业科学 2017年第6期43卷 913-921页

作者：何芬赵巧玲王明磊王平阳夏定国裘智勇唐顺明沈兴家江苏科技大学生物技术学院江苏省蚕桑生物学与生物技术重点实验室江苏镇江212018 中国农业科学院蚕业研究所农业部蚕桑遗传改良重点实验室江苏镇江212018

在家蚕品种C1(H)中发现了一种新的卵色突变体。该突变体卵色为淡红色,成虫复眼为红色,遗传分析表明该突变性状由1个隐性基因控制,可能与红卵突变基因re互为等位基因,命名为淡红卵突变体(pale red egg,re^p-1)。红卵突变体(re)被认为是MF... 详细信息

在家蚕品种C1(H)中发现了一种新的卵色突变体。该突变体卵色为淡红色,成虫复眼为红色,遗传分析表明该突变性状由1个隐性基因控制,可能与红卵突变基因re互为等位基因,命名为淡红卵突变体(pale red egg,re^p-1)。红卵突变体(re)被认为是MFS(major facilitator superfamily)基因的序列发生了改变,故对re^p-1突变体MFS基因的结构及表达进行分析。与C1(H)卵色正常型品系的MFS基因比较,re^p-1突变体的MFS基因在第6外显子中的一段长59 bp片段被长14 bp的片段所替换,但编码蛋白质的跨膜结构未发生根本改变,而re突变体中MFS基因的结构变化对表达产物的功能有显著影响。此外,利用qRT-PCR检测MFS基因在C1(H)的卵色正常型品系、re^p-1突变体和re突变体3个家蚕品系5龄幼虫各个组织中均有表达,但表达水平存在差异:相较于C1(H)卵色正常型品系和re^p-1突变体,re突变体所有组织中MFS基因的表达量普遍偏低;相较于C1(H)卵色正常型品系,re^p-1突变体的后部丝腺和精巢中MFS基因具有较高的表达量,在其他组织中的表达量无明显差异。上述结果将有助于对re^p-1突变基因定位分析和卵色突变形成机制的研究。

关键词：家蚕卵色突变淡红色卵突变体遗传分析 MFS基因序列组成组织表达

贝伐珠单抗联合mFOLFOX6方案治疗晚期结肠癌的临床效果及对血清CEA的影响

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中国医药科学 2017年第10期7卷 11-14页

作者：陈志勇陈珍丘金花郑秋香黄文金福建医科大学附属龙岩第一医院肿瘤科福建龙岩364000

目的探讨贝伐珠单抗与m FOLFOX6方案联合治疗晚期结肠癌的临床价值。方法选取2013年1月~2016年1月我院收治的晚期结肠癌患者58例为研究对象,经随机数字表法分为观察组与对照组,每组29例,对照组给予m FOLFOX6化疗方案治疗,观察组在对照... 详细信息

目的探讨贝伐珠单抗与m FOLFOX6方案联合治疗晚期结肠癌的临床价值。方法选取2013年1月~2016年1月我院收治的晚期结肠癌患者58例为研究对象,经随机数字表法分为观察组与对照组,每组29例,对照组给予m FOLFOX6化疗方案治疗,观察组在对照组基础上加用贝伐珠单抗治疗,观察两组治疗效果、不良反应发生情况、无进展存活时间(PFS)及血清癌胚抗原(CEA)水平变化。结果观察组治疗总有效率为51.72%,同对照组24.14%比较,显著较高,差异有统计学意义(P0.05);观察组PFS时间同对照组比较,显著较长,差异有统计学意义(P0.05),治疗后均有下降,观察组治疗后血清CEA水平明显较对照组低,差异有统计学意义(P<0.05)。结论晚期结肠癌患者接受贝伐珠单抗联合m FOLFOX6方案治疗,近远期效果确切,可明显降低血清肿瘤标志物浓度,且具有较高安全性,值得推广。

关键词：晚期结肠癌化疗贝伐珠单抗无进展存活时间癌胚抗原

A dual-mode image sensor using an all-inorganic perovskite nanowire array for standard and neuromorphic imaging

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Journal of Semiconductors 2023年第9期44卷 75-82页

作者： Zhenghao Long Yucheng Ding Xiao qiu Yu Zhou Shivam Kumar zhiyong Fan Department of Electronic and Computer Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong Kong SARChina State Key Laboratory of Advanced Displays and Optoelectronics Technologies HKUSTClear Water BayKowloonHong Kong SARChina Department of Chemical and Biological Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong Kong SARChina Shanghai Artificial Intelligence Laboratory Shanghai 200232China

The high-density,vertically aligned retinal neuron array provides effective vision,a feature we aim to replicate with electronic ***,the conventional complementary metal-oxide-semiconductor(CMOS)image sensor,based on separate designs for sensing,memory,and processing units,limits its integration ***,redundant signal communication significantly increases energy *** neuromorphic devices integrating sensing and signal processing show promise in various computer vision applications,but there is still a need for frame-based imaging with good *** this study,we developed a dual-mode image sensor based on a high-density all-inorganic perovskite nanowire *** device can switch between frame-based standard imaging mode and neuromorphic imaging mode by applying different *** unique bias-dependent photo response is based on a well-designed energy band *** biomimetic alignment of nanowires ensures the potential for high-resolution *** further demonstrate the imaging ability,we conducted pattern reconstruction in both modes with a 10×10 crossbar *** study introduces a novel image sensor with high compatibility and efficiency,suitable for various applications including computer vision,surveillance,and robotics.

关键词： mode image inorganic

Effect of solidification rate on the coarsening behavior of precipitate in rapidly solidified Al-Si alloy

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Progress in Natural Science:Materials International 2016年第4期26卷 391-397页

作者： zhiyong Cai Chun Zhang Richu Wang Chaoqun Peng Ke qiu Naiguang Wang School of Materials Science and Engineering Jiangxi University of Science and Technology School of Materials Science and Engineering Central South University

The gas-atomized Al-Si alloy powder with different particle sizes was subjected to isothermal annealing for understanding the effect of solidification rate on precipitation and growth Si crystals. The results show that Si precipitates grew more quickly in the small samples with a large solidification rate due to high interfacial energy. Moreover, these Si crystals had a tendency to form a quasi-spherical shape after annealing at a low temperature or for a short holding time. Coarsening of the Si precipitates during annealing was examined using a LSW equation. Thermal stability of the rapidly solidified alloy was significantly influenced by its original microstructure as a result of high solidification rate. Furthermore,more serious clustering of Si-Si phase was also observed in the small samples, attributed to the rapid coarsening of the Si phases.

关键词： Rapid solidification Solidification rate Super-saturated solutions Grain growth Aluminum Silicon alloy

Current progress in developing metal oxide nanoarrays-based photoanodes for photoelectrochemical water splitting

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Science Bulletin 2019年第18期64卷 1348-1380页

作者： Yongcai qiu Zhenghui Pan Haining Chen Daiqi Ye Lin Guo zhiyong Fan Shihe Yang Guangdong Provincial Key Laboratory of Atmospheric Environment and Pollution Control School of Environment and EnergySouth China University of TechnologyGuangzhou 510006China State Key Laboratory of Luminescent Materials and Devices South China University of TechnologyGuangzhou 510640China Department of Materials Science and Engineering National University of SingaporeSingapore 117574Singapore School of Materials Science and Engineering Beihang UniversityBeijing 100191China School of Chemistry and Environment Beihang UniversityBeijing 100191China Department of Electronic and Computer Engineering The Hong Kong University of Science and TechnologyHong KongChina Department of Chemistry The Hong Kong University of Science and TechnologyHong KongChina Guangdong Key Lab of Nano-Micro Material Research School of Chemical Biology and Biotechnology Shenzhen Graduate SchoolPeking UniversityShenzhen 518055China

Solar energy driven photoelectrochemical(PEC) water splitting is a clean and powerful approach for renewable hydrogen production. The design and construction of metal oxide based nanoarray photoanodes is one of the promising strategies to make the continuous breakthroughs in solar to hydrogen conversion efficiency of PEC cells owing to their owned several advantages including enhanced reactive surface at the electrode/electrolyte interface, improved light absorption capability, increased charge separation efficiency and direct electron transport pathways. In this Review, we first introduce the structure,work principle and their relevant efficiency calculations of a PEC cell. We then give a summary of the state-of the-art research in the preparation strategies and growth mechanism for the metal oxide based nanoarrays, and some details about the performances of metal oxide based nanoarray photoanodes for PEC water splitting. Finally, we discuss key aspects which should be addressed in continued work on realizing high-efficiency metal oxide based nanoarray photoanodes for PEC solar water splitting systems.

关键词： Photoelectrochemical water splitting Metal oxide based nanoarray photoanodes Preparation strategies and growth mechanism

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煤气管道用耐酸钢硫酸腐蚀行为研究

轧钢 2021年第1期38卷 26-30,35页

作者：邱志永胡学文高秀华石践吴红艳于驰东北大学轧制技术及连轧自动化国家重点实验室辽宁沈阳110819 马鞍山钢铁股份有限公司技术中心安徽马鞍山243000 东北大学秦皇岛分校资源与材料学院河北秦皇岛066004

高炉煤气输送管道通常采用普碳钢,而煤气管道中含有硫酸、硝酸和氯离子等多种腐蚀性介质,对管道造成腐蚀,管道使用寿命低。针对研发的煤气管道用耐酸钢,采用均匀腐蚀全浸试验对其硫酸腐蚀行为进行了研究,利用扫描电镜(SEM)、电子探针(EP... 详细信息

高炉煤气输送管道通常采用普碳钢,而煤气管道中含有硫酸、硝酸和氯离子等多种腐蚀性介质,对管道造成腐蚀,管道使用寿命低。针对研发的煤气管道用耐酸钢,采用均匀腐蚀全浸试验对其硫酸腐蚀行为进行了研究,利用扫描电镜(SEM)、电子探针(EPMA)、激光共焦扫描显微镜(LSCM)等手段揭示其腐蚀行为。结果表明,煤气管道用耐酸钢有优异的耐硫酸腐蚀性能;Cu、Sb、Cr等耐腐蚀元素的加入有利于改善点蚀现象,并在耐酸钢表面形成一层致密的不溶于硫酸的富含Cu、Sb、Cr等元素的钝化膜,从而增强耐酸钢的耐硫酸腐蚀性能;适量的S元素含量有利于提高钢的耐硫酸腐蚀性能。

关键词：耐酸钢煤气管道均匀腐蚀硫酸腐蚀电子探针点蚀 S元素含量钝化膜

Remarkably Enhanced Hydrogen Oxidation Reaction Activity of Carbon-supported Pt by Facile Nickel Modification

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Chemical Research in Chinese Universities 2020年第1期36卷 105-109页

作者： HUANG Xuewei LONG Chang HAN Jianyu ZHANG Jing qiu Xueying TANG zhiyong College of Chemistry Zhengzhou UniversityZhengzhou 450001P.R.China CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190P.R.China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150080P.R.China Institute of Applied Chemistry Shanxi UniversityTaiyuan 030006P.R.China

Developing high activity catalysts for hydrogen oxidation reaction(HOR)under alkaline condition remains a challenge in the exchange membrane fuel cell(AEMFC).Herein,we report that the activity of carbon-supported platinum(Pt/C)towards the hydrogen oxidation reaction(HOR)in alkaline media can be remarkably enhanced by simple immersion of Pt/C in nickel chloride *** adsorption of hydrogen on the catalyst surface is weakened by modification of *** HOR activity on the Pt/C after immersion possesses an excellent mass current density of 33.4 A/gmetal,which is 18%higher than that(28.3 A/gmetal)on Pt/C.

关键词： Electrocatalyst Hydrogen oxidation Pt/C Modified nickel

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一款水杨酸去屑洗发水的性能研究

广东化工 2022年第12期49卷 67-70页

作者：刘怡玲卓珊珊杨杏邱志勇梁嘉宜欧婷婷澳宝化妆品(惠州)有限公司研发中心广东惠州441301

目的:一款含水杨酸原料化妆品的性能。方法:按照相关标准和方法对具有去屑功效的化妆品进行了内控测试、安全性试验、人体功效评价的半定量评估和实验室试验。结论:相比用样前,该样品内控指标满足产品要求,并通过安全性测试,人体功效评... 详细信息

目的:一款含水杨酸原料化妆品的性能。方法:按照相关标准和方法对具有去屑功效的化妆品进行了内控测试、安全性试验、人体功效评价的半定量评估和实验室试验。结论:相比用样前,该样品内控指标满足产品要求,并通过安全性测试,人体功效评价和实验室试验显示该样品具有去屑功效、护发、柔顺功效。

关键词：去屑功效人体功效评价图像分析性能研究实验室试验

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含AOS原料的洗护产品的性能研究

广东化工 2022年第8期49卷 59-62页

作者：卓珊珊刘怡玲梁嘉宜邱志勇欧婷婷杨杏澳宝化妆品(惠州)有限公司研发中心广东惠州441301

文章主要探讨几款含AOS原料的固色护色功效洗护产品的功效宣称。按照相关标准和方法对几款具有固色护色功效的洗护产品进行了内控测试、安全性试验和在体外功效性评价试验,从而探究固色护色洗护类产品的性能。内控测试包括化妆品的理化... 详细信息

文章主要探讨几款含AOS原料的固色护色功效洗护产品的功效宣称。按照相关标准和方法对几款具有固色护色功效的洗护产品进行了内控测试、安全性试验和在体外功效性评价试验,从而探究固色护色洗护类产品的性能。内控测试包括化妆品的理化酸碱度测试和稳定性测试,安全性试验为鸡胚绒毛尿囊膜试验和斑贴测试,体外功效性评价试验则是通过颜色测试探头在同一条件下测定染色的离体真人离体发束的色差,验证产品的固色效果。结果表明:几款洗护产品通过了内控指标测试,产品安全性为中度刺激,因该产品不直接接触眼部,所以该产品安全性通过,并且体外功效评价具有显著固色护色的功效。

关键词：发色护理洗护产品体外功效性评价功效宣称固色护色