检索结果-南通市图书馆

Proxitome profiling reveals a conserved SGT1-NSL1 signaling module that activates NLR-mediated immunity

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Molecular Plant 2024年第9期17卷 1369-1391页

作者： Dingliang Zhang Xinxin Yang zhiyan wen Zhen Li Xinyu Zhang Chenchen Zhong Jiajie She Qianshen Zhang He Zhang wenli Li Xiaoyun Zhao Mingliang Xu Zhen Su Dawei Li Savithramma P.Dinesh-Kumar Yongliang Zhang State Key Laboratory of Plant Environmental Resilience College of Biological SciencesChina Agricultural UniversityBejing 100193China Department of Plant Biology and The Genome Center College of Biological SciencesUniversity of CaliforniaDavisDavisCA 95616USA State Key Laboratory of Plant Environmental Resilience College of Agronomy and BiotechnologyChina Agricultural UniversityBejing 100193China

Suppressor of G2 allele of skp1(SGT1)is a highly conserved eukaryotic protein that plays a vital role in growth,development,and immunity in both animals and *** some SGT1 interactors have been identified,the molecular regulatory network of SGT1 remains ***1 serves as a co-chaperone to stabilize protein complexes such as the nucleotide-binding leucine-rich repeat(NLR)class of immune receptors,thereby positively regulating plant ***1 has also been found to be asso-ciated with the SKP1-Cullin-F-box(SCF)E3 ubiquitin ligase ***,whether SGT1 targets im-mune repressors to coordinate plant immune activation remains *** this study,we constructed a toolbox for TurbolD-and split-TurbolD-based proximity labeling(PL)assays in Nicotiana benthamiana and used the PL toolbox to explore the SGT1 interactome during pre-and post-immune *** comprehensive SGT1 interactome network we identified highlights a dynamic shift from proteins associ-ated with plant development to those linked with plant immune *** found that SGT1 interacts with Necrotic Spotted Lesion1(NSL1),which negatively regulates salicylic acid-mediated defenseby inter-fering with the nucleocytoplasmic trafficking of non-expressor of pathogenesis-related genes 1(NPR1)during N NLR-mediated response to tobacco mosaic ***1 promotes the SCF-dependent degrada-tion of NSL1 to facilitate immune activation,while salicylate-induced protein kinase-mediated phosphory-lation of SGT1further potentiates this *** NNLR,NSL1also functions in several other NLR-mediated ***,our study unveils the regulatory landscape of SGT1 and reveals a novel SGT1-NSL1 signaling module that orchestrates plant innate immunity.

关键词： suppressor of G2 allele of skp1 SGT1 proximity labeling N NLR immune receptor Necrotic Spotted Lesion 1 NSL1 salicylic acid ubiquitination

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杜定友与刘国钧分类思想异同探析

图书馆工作与研究 2011年第11期 13-15页

作者：张智燕刘雯西安交通大学图书馆

刘国钧与杜定友是中国近现代图书分类学的开创者和奠基者。本文从他们对古今中外图书统一分类、分类法标准化以及分类法与主题法兼容等图书分类发展历史上的热点问题的各自观点,探讨其学术思想异同及思想差异产生的根源。

关键词：杜定友刘国钧分类学比较研究图书馆学术史

自媒体时代主流意识形态网络空间话语权建构研究

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中共四川省委党校学报 2021年第1期 81-86页

作者：张红霞四川水利职业技术学院马克思主义学院四川成都611131

自媒体时代,意识形态在网络空间面临一系列新挑战、新要求,与时俱进地提出加强主流意识形态网络空间话语权建构的时代命题就显得非常必要。自媒体独具开放性、互动性、即时性、平民化等显著特征,且其本身具有一定的意识形态属性,这就为... 详细信息

自媒体时代,意识形态在网络空间面临一系列新挑战、新要求,与时俱进地提出加强主流意识形态网络空间话语权建构的时代命题就显得非常必要。自媒体独具开放性、互动性、即时性、平民化等显著特征,且其本身具有一定的意识形态属性,这就为进一步巩固主流意识形态网络阵地提供了可能性。结合自媒体时代发展要求和意识形态领域面临的新挑战,发挥自媒体的优势作用,加快创新提升网络空间话语权的实践路径,是新时代建构主流意识形态话语权和主导权的现实要求。

关键词：自媒体时代主流意识形态网络空间话语权

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A Preliminary Study of Contrast-enhanced Ultrasound in Tumor-related Obstructive Atelectasis

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A Preliminary Study of Contrast-enhanced Ultrasound in Tumor...

Review of Chinese atmospheric science research over the past 70 years: Climate and climate change

2008年浙江省超声医学学术年会

作者： Luo zhiyan Liu Xueming wen Qing et al Department of Ultrasound,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 31000,China

Objective To explore the characteristics of the tumor-related obstructive atelectasis (OA) on contrast- enhanced ultrasound (CEUS). Materials and methods Fourteen tumor-related obstructive atelectasis patients confirmed by surgery and bronchofibroscope (six squamous carcinoma,four adenocarcinoma,one adenosquamous carcinoma,one small-cell carcinoma,one metastatic tumor and one carcinoma sarcomatodes) underwent contrast-enhanced

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Science China Earth Sciences 2019年第10期62卷 1514-1550页

作者： Jianping HUANG wen CHEN Zhiping wen Guangjun ZHANG Zhaoxin LI zhiyan ZUO Qingyun ZHAO College of Atmospheric Sciences Lanzhou UniversityLanzhou730000China Center for Monsoon System Research Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing100190China Department of Atmospheric and Oceanic Sciences Fudan UniversityShanghai200438China Scripps Institution of Oceanography University of CaliforniaSan Diego92093USA Laboratoire de Météorologie Dynamique CNRSSorbonne UniversitéParis75005France Chinese Academy of Meteorological Sciences Beijing100081China

Climate and climate change have always been a research focus of atmospheric sciences. This paper summaries research efforts, achievements and international contributions of the Chinese scientific community on climate and climate change over the past 70 years. The review is based on papers published officially in national or international scientific journals,and is organized to cover six aspects:(1) general climate studies;(2) impact of the Qinghai-Tibetan Plateau;(3) impact of the East Asian monsoon;(4) influences of teleconnection oscillation and westerlies;(5) climate dynamics and development of climate models;and(6) climate change. It is, however, to be noted that the present review can not be considered as an exhaustive one, since there is a huge body of literature in the field.

关键词： Climate of China Qinghai-Tibetan Plateau East Asian Monsoon Climate change

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Engineering and Application of Pillar[6]arene Functionalized Chiral Surface in Selective Adsorption of R-Adrenaline

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Chinese Journal of Chemistry 2022年第8期40卷 925-930页

作者： Ming Cheng wen Gong Mingxiang Lu Junkai Ma zhiyan Lu Haibing Li Hubei Key Laboratory of Wudang Local Chinese Medicine Research Department of ChemistrySchool of PharmacyHubei University of MedicineShiyanHubei 442000China Department of Forensic Medicine Zhongnan Hospital of Wuhan UniversityNo.169 East Lake RoadWuchang DistrictWuhanHubei 430071China Key Laboratory of Pesticide and Chemical Biology(CCNU) Ministry of EducationCollege of ChemistryCentral China Normal UniversityWuhanHubei 430079China Department of Cardiology The Third People's Hospital of Hubei Province Hospital of Hubei ProvinceWuhanHubei 430030China

Chiral properties of biological surface is of importance as they dominate interactions with biomolecules(such as proteins,nucleic acids,hormones)in a living *** by this phenomenon,we designed and constructed a L-/D-N-acetyl-cysteine-pillar[6]arene functionalized Si surface(L-/D-NACP surface)for studying the influence of superficial chirality on selective adsorption of *** fabricated chiral L-/D-NACP surface with consistency in hydrophilia and elementary composition exhibited a strong mirror-symmetric circular dichroism *** the adsorption study,the contact-angle of R-adrenaline droplet on D-NACP surface was more hydrophilic from macroscopical view,and the size and quantity of R-adrenaline aggregation on D-NACP surface was larger than L-NACP surface,implying selective adsorption of R-adrenaline appeared on the D-NACP *** possible mechanism was due to the stronger host-guest interaction between D-NACP and R-adrenaline,which facilitated the selective ***,the D-NACP surface with good selectivity can be used for chiral separation of racemic *** results enhance the under-standing of hormones adsorption affected by surface chirality,and may provide some helpful inspiration for practical application of chiral surface.

关键词： R-Adrenaline Pillararene Chiral surface Molecular recognition Host-guest systems

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合成孔径激光雷达成像研究进展综述

河北工业大学学报 2024年第5期53卷 1-12,86页

作者：王兆成宿博瑜程雨佳文志颜张宝林于宇河北工业大学电子信息工程学院天津300401

激光成像雷达是一种处理目标散射光成像的设备,在探测精度上有显著优势,但是分辨率受波束宽度和目标距离限制,因此将其与合成孔径技术相结合,得到合成孔径激光雷达(Synthetic Aperture Li-dar,SAL)。SAL作为一种主动探测雷达,拥有更短... 详细信息

激光成像雷达是一种处理目标散射光成像的设备,在探测精度上有显著优势,但是分辨率受波束宽度和目标距离限制,因此将其与合成孔径技术相结合,得到合成孔径激光雷达(Synthetic Aperture Li-dar,SAL)。SAL作为一种主动探测雷达,拥有更短的合成孔径时间,且成像分辨率与距离无关,可以进行大面积成像,已经成为国内外的研究热点。除此之外,SAL还具有体积小、重量轻、抗干扰强等特点,因此难以被侦测,具有良好的军用和民用潜质。但是由于激光波长短,必然会引起相位误差以及调制受限等难题,本文主要就相位误差处理、光视场优化和ISAL三方面对近十年SAL的研究发展进行了概述,具体分析了不同方法的原理、所解决的问题以及所遇到的瓶颈,并根据其发展趋势进行了预测和展望。

关键词：激光雷达合成孔径技术相位误差补偿光视场逆合成孔径激光雷达

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Constructing bimodal nanoprobe based on Gd:AgInS_(2)/ZnS quantum dots for fluorometric/magnetic resonance imaging in mesenchymal stem cells

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Journal of Materials Science & Technology 2023年第17期148卷 116-122页

作者： Dan Yang Xian Wei zhiyan Piao Zhongjie Cui Haiyang He Zhuoqi wen Wanlu Zhang Le Wang Shiliang Mei Ruiqian Guo Institute for Electric Light Sources School of Information Science and TechnologyFudan UniversityShanghai 200433China College of Electronic and Optical Engineering&College of Flexible Electronics Nanjing University of Posts and TelecommunicationsNanjing 210023China Academy for Engineering and Technology Fudan UniversityShanghai 200433China Zhongshan-Fudan Joint Innovation Center Zhongshan 528437China Yiwu Research Institute of Fudan University Yiwu 322000China

Mesenchymal stem cells(MSCs)hold great promise in regenerative medicine and received overwhelm-ing concerns to promote their therapeutic *** to the shortage of MSCs-specific biomarkers,bimodal imaging nanoprobes with integrated complementary information are of great importance in ameliorating the efficacy of MSCs terminal *** this study,a noninvasive dual-mode imaging nanoprobe with enhanced detection sensitivity and spatial resolution based on alloyed Gd:AgInS_(2)/ZnS quantum dots(QDs)was first fabricated through a microwave-assisted heating *** QDs with red emissive fluorescence exhibit excellent biocompatibility in MSCs under a confocal *** for magnetic resonance imaging(MRI),the longitudinal relaxation rate of 11.1420 mM^(-1) S^(-1) of Gd:AgInS_(2)/ZnS QDs was achieved,which was 1.7 times higher than that of commercial MRI contrast agent(6.4667 mM^(-1) S^(-1)).Furthermore,the cellular internalization of Gd:AgInS_(2)/ZnS QDs exerts no significant effect on the adipogenesis of MSCs and is conducive to the observation of further adipogenic *** work helps to verify the promising prospect to develop a bimodal nanoprobe of fluorescence/MRI based on Gd:AgInS_(2)/ZnS QDs,which could monitor the differentiation and migration of MSCs for further therapeu-tic approach.

关键词： AgInS_(2)quantum dots Gd doping Dual-mode imaging Mesenchymal stem cells Differentiation

Proteomic Study of Differentially Expressed Proteins in Seeds between Parents and Offspring of Castor Bean(Ricinus communis L.)

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Phyton-International Journal of Experimental Botany 2023年第6期92卷 1765-1792页

作者： Xiaotian Liang Qi wen Rui Luo Yanxin Zhang Mingda Yin Yanpeng wen Xuemei Hu zhiyan Wang Yumiao Huo Fenglan Huang College of Life Science and Food Engineering Inner Mongolia Minzu UniversityTongliao028000China Key Laboratory of Castor Breeding of State Ethnic Affairs Commission Tongliao028000China Research Center for Engineering and Technology of Castor Industry by Universities in Inner Mongolia Autonomous Region Tongliao028000China Key Laboratory of Castor Breeding of Inner Mongolia Autonomous Region Tongliao028000China Collaborative Innovation Center of Castor Industry of Inner Mongolia Autonomous Region Tongliao028000China Engineering Research Center of Castor Industry Technology Innovation Inner Mongolia Autonomous RegionTongliao028000China

Castor bean(Ricinus communis L.),is one of the top 10 oilseed crops in the world and,therefore,of high economic *** is one of the most effective ways to breed new varieties with high yield,high oil content,and better stress ***,prediction of desired traits in castor hybrid offspring is particularly *** this study,proteomic analysis was performed to identify differentially expressed proteins(DEPs)in seeds between castor hybrid offspring and their female(Lm female line aLmAB2)and male parents(CSR·181).Among the DEPs upregulated in the seeds of hybrid offspring,the majority were related to seed yield and stress tolerance,while some were related to oil synthesis and fatty acid synthesis and metabolism in *** other words,the hybrid offspring showed heterosis for seed yield,stress tolerance,oil synthesis,and fatty acid synthesis and metabolism when compared with their ***,real-time quantitative polymerase chain reaction assays were performed on 12 genes encoding DEPs involved in oil synthesis,pollen abortion,yield,and stress tolerance of *** results showed that the expression levels of the 12 genes were consistent with those of the DEPs.

关键词： Castor bean 2D-DIGE heterosis