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The Earth Summit Mission-2022:Successful ozone soundings contribute to source identification in the north Mt.Qomolangma region

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Journal of Environmental Sciences 2024年第2期136卷 412-421页

作者： Jinqiang Zhang Chunxiang Ye Yuejian Xuan zhixuan Bai Weili lin Dan li lingkun Ran Baofeng Jiao YaomingMa Weiqiang Ma Nan Yao Yunshu Zeng Daren Lv Tong Zhu Key Laboratory of Middle Atmosphere and Global Environment Observation Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China College of Environmental Sciences and Engineering Center for Environment and HealthPeking UniversityBeijing 100871China Key Laboratory of Ecology and Environment in Minority Areas(Minzu University of China) National Ethnic Affairs CommissionBeijing 100081China Key Laboratory of Cloud-Precipitation Physics and Severe Storms Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Land-Atmosphere Interaction and Its Climatic Effects Group State Key Laboratory of Tibetan Plateau Earth SystemResources and Environment(TPESRE)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China College of Atmospheric Science Lanzhou UniversityLanzhou 730000China National Observation and Research Station for Qomolongma Special Atmospheric Processes and Environmental Changes Dingri 858200China Kathmandu Center of Research and Education Chinese Academy of SciencesBeijing 100101China China-Pakistan Joint Research Center on Earth Sciences Chinese Academy of SciencesIslamabad 45320Pakistan Electronic Engineering College Chengdu University of Information TechnologyChengdu 610225China

As part of“The Earth Summit Mission-2022”during the second Tibetan Plateau Scientific Expedition and Research(STEP)in April and May 2022,we conducted the ozone sounding experiment(an ozonesonde mated to a radiosonde)at Mt.Qomolangma Base Camp(MQBC;86.85°E,28.14°N;5200 m),a location at an extremely high altitude.A total of ten sounding profiles were obtained between April 30 and May 06,2022,of which seven profiles were above35 km in altitude,with a maximum detection altitude up to 39.0 km.This study presents the temporal variation and vertical distributions of atmospheric temperature,humidity,and ozone during the MQBC campaign.The averaged ozone concentration was high(68.3 ppbv)at the surface and then increased smoothly until peaking(~110 ppbv)in the middle troposphere(approximately 10 km),and afterward,the ozone concentration increased rapidly from the upper troposphere to a maximum of~10 ppmv at~30 km.The enhanced ozone concentration in the middle troposphere was associated with the blocking high pressure,and transport from the southern flank of the Himalayas occurred during the campaign period.The average total ozone column was 291.9±21.4 DU for the seven profiles exceeding 35km in altitude.The ozonesonde measurements were also compared with the vertical ozone profiles retrieved from the space-borne ozone products from the Microwave limb Sounder(MLS)onboard the Aura satellite and the Atmospheric Infrared Sounder(AIRS)onboard the Aqua satellite.

关键词： Ozone soundings Mt.Qomolangma Vertical ozone structure Ozone source Satellite data

Modulation of gut microbiota and serum metabolome by Apostichopus japonicus derived oligopeptide in high-fructose diet-induced hyperuricemia in mice

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Food Science and Human Wellness 2024年

作者： Jun Zhou Ziyan Wang zhixuan Zhang Jiaojiao Han Ying Feng Jing Zhang Zhen Zhang Ye li Tinghong Ming Chenyang Lu Rixin Wang Xiurong Su School of Marine Science Ningbo University Faculty of Food Science Zhejiang Pharmaceutical College Key Laboratory of Aquacultural Biotechnology Ministry of Education Ningbo University College of life Sciences Tonghua Normal University State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products Ningbo University

Fructose consumption has risen dramatically in recent decades due to the use of sucrose and high fructose corn syrup in beverages and processed foods， contributing to rising rates of hyperuricemia. The purpose of this experiment was to explore the anti-hyperuricemia effects of an active oligopeptide (GPSGRP) derived from sea cucumber in fructose induced hyperuricemia mouse model， and to clarify the underlying mechanism in sight of gut microbiota and serum metabolites. Peptide GPSGRP treatment rebalanced uric acid metabolism and alleviated inflammatory response in mice. In addition， treatment with GPSGRP decreased the abundance of Bacteroides and Proteobacteria at the phylum level， Muribaculum， Prevotella and Bacteroides at the genus level， and inhibited the related pathways of purine metabolism and glycolysis/gluconeogenesis metabolism. Moreover， serum metabolites， including linoleic acid， indole and its derivatives， arachidonic acid and uridine， as well as related metabolic pathways， such as tricarboxylic acid cycle， ketone production and sugar production， were altered in response to GPSGRP treatment. This study provides a valuable reference for the application and development of marine biological peptides in uric acid management.

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风光储参与电网预防-紧急控制策略研究

太阳能学报 2024年第4期45卷 404-415页

作者：万庆祝袁润娇李伊梦李治萱北方工业大学电气与控制工程学院北京100144

基于风光储有功功率连续平滑调节能力,提出一种风光储协同切负荷优化的电网预防-紧急控制策略。首先,分析风光储参与电网预防-紧急控制原理,给出风光储参与电网预防-紧急控制策略。在故障发生前通过削减风光出力预留有功备用容量,通过... 详细信息

基于风光储有功功率连续平滑调节能力,提出一种风光储协同切负荷优化的电网预防-紧急控制策略。首先,分析风光储参与电网预防-紧急控制原理,给出风光储参与电网预防-紧急控制策略。在故障发生前通过削减风光出力预留有功备用容量,通过调整发电机机组出力、储能充放电状态平抑风光出力改变引起的系统功率波动;在故障发生后,优先考虑风光预留有功备用量填补系统功率不平衡量,若风光预留有功备用量不足,则采取切负荷措施进行紧急控制。然后,综合考虑风光有功备用成本、预防、紧急控制措施成本,分别建立风光储参与电网预防、紧急控制模型,采用Matlab/CPLEX求解模型。最后在改进IEEE 39节点系统进行仿真验证本文所提控制策略的有效性。

关键词：可再生能源优化成本风光有功备用预防-紧急控制策略

Comparison between ozonesonde measurements and satellite retrievals over Beijing,China

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Atmospheric and Oceanic Science Letters 2024年第1期17卷 14-20页

作者： Jinqiang Zhang Yuejian Xuan Jianchun Bian Holger Vomel Yunshu Zeng zhixuan Bai Dan li Hongbin Chen Key Laboratory of Middle Atmosphere and Global Environment Observation Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijingChina College of Atmospheric Sciences Lanzhou UniversityLanzhouChina National Center for Atmospheric Research BoulderCOUSA Electronic Engineering College Chengdu University of Information TechnologyChengduChina

从2013年开始,作者团队使用自主研发电化学原理臭氧探空仪在华北平原北京地区进行每周一次观测.本研究首次使用2013-2019年期间北京地区臭氧探空数据评估Aqua卫星搭载大气红外探测仪(AIRS)和Aura卫星搭载微波临边探测器(MLS)反演垂直臭... 详细信息

从2013年开始,作者团队使用自主研发电化学原理臭氧探空仪在华北平原北京地区进行每周一次观测.本研究首次使用2013-2019年期间北京地区臭氧探空数据评估Aqua卫星搭载大气红外探测仪(AIRS)和Aura卫星搭载微波临边探测器(MLS)反演垂直臭氧廓线,并对比臭氧探空,AIRS和Aura卫星搭载臭氧监测仪(OMI)臭氧柱总量结果.尽管臭氧探空与卫星反演垂直臭氧廓线在局部高度处差异较大,但整体来说两者较为接近(相对偏差大多<10%).臭氧探空,AIRS和OMI三种仪器测量臭氧柱总量的年变化特征较为一致,其年均臭氧柱总量分别为351.8±18.4 DU,348.8±19.5 DU和336.9±14.2 DU.后续对国内多站点观测数据分析将有助于进一步理解臭氧探空与卫星反演臭氧资料在不同区域的一致性.

关键词：臭氧探空卫星反演垂直臭氧廓线臭氧柱总量华北平原

Multi-objective interval prediction of wind power based on conditional copula function

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Journal of Modern Power Systems and Clean Energy 2019年第4期7卷 802-812页

作者： Gang ZHANG zhixuan li Kaoshe ZHANG Lei ZHANG Xia HUA Yongqing WANG Institute of Water Resources and Hydro-Electric Engineering Xi’an University of TechnologyXi’an 710048China State Grid Shaanxi Baoji Electric Power Company Baoji 721000China State Grid Gansu Electric Power Company Gansu Electric Power Research InstituteLanzhou 730050China State Grid Shaanxi Electric Power Company Shaanxi Electric Power Research InstituteXi’an 710054China

Interval prediction of wind power,which features the upper and lower limits of wind power at a given confidence level,plays a significant role in accurate prediction and stability of the power grid integrated with wind power.However,the conventional methods of interval prediction are commonly based on a hypothetic probability distribution function,which neglects the correlations among various variables,leading to the decrease of prediction accuracy.Therefore,we improve the multi-objective interval prediction based on the conditional copula function,through which we can fully utilize the correlations among variables to improve prediction accuracy without an assumed probability distribution function.We use the multi-objective optimization method of nondominated sorting genetic algorithm-II(NSGA-II)to obtain the optimal solution set.The particular best solution is weighted by the prediction interval average width(PIAW)and prediction interval coverage probability(PICP)to pick the optimized solution in practical examples.Finally,we apply the proposed method to three wind power plants in different cities in China as examples forvalidation and obtain higher prediction accuracy compared with other methods,i.e.,relevance vector machine(RVM),artificial neural network(ANN),and particle swarm optimization kernel extreme learning machine(PSO-KELM).These results demonstrate the superiority and practicability of this method in interval prediction of wind power.

关键词： Wind power prediction Interval prediction Conditional copula function Empirical distribution function Multi-objective optimization algorithm

“互联网+”背景下思政教育融入大学生就业创业课程的策略探究

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长治学院学报 2024年第2期41卷 128-132页

作者：李芷萱山西传媒学院动画与数字艺术学院山西太原030000

随着互联网的迅猛发展和广泛渗透,其对各行各业尤其是对教育领域的影响不容忽视。在“互联网+”的背景下,思政教育在大学生就业创业课程中的角色和价值正日益凸显。文章立足“互联网+”时代背景,就思政教育如何更好地融入并优化大学生... 详细信息

随着互联网的迅猛发展和广泛渗透,其对各行各业尤其是对教育领域的影响不容忽视。在“互联网+”的背景下,思政教育在大学生就业创业课程中的角色和价值正日益凸显。文章立足“互联网+”时代背景,就思政教育如何更好地融入并优化大学生的就业创业课程以及其在实际应用中所面临的问题和对策进行了探讨。通过系统分析当前的教育模式,本研究希望能够为提升思政教育在就业创业课程中的实效性提供理论支撑和实践指导。

关键词： “互联网+” 思政教育大学生就业创业课程教学创新

Aristolochic acids exposure was not the main cause of liver tumorigenesis in adulthood

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Acta Pharmaceutica Sinica B 2022年第5期12卷 2252-2267页

作者： Shuzhen Chen Yaping Dong Xinming Qi Qiqi Cao Tao Luo Zhaofang Bai Huisi He Zhecai Fan lingyan Xu Guozhen Xing Chunyu Wang Zhichao Jin zhixuan li Lei Chen Yishan Zhong Jiao Wang Jia Ge Xiaohe Xiao Xiuwu Bian Wen Wen Jin Ren Hongyang Wang National Center for liver Cancer Second Military Medical UniversityShanghai 200438China International Cooperation Laboratory on Signal Transduction Eastern Hepatobiliary Surgery HospitalSecond Military Medical UniversityShanghai 200438China Center for Drug Safety Evaluation and Research State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Fudan University Shanghai Cancer Center Shanghai 200032China The Graduate School of Fujian Medical University Fuzhou 350122China Institute of Pathology Southwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China Key Laboratory of Tumor Immunopathology Ministry of Education of ChinaChongqing 400038China China Military Institute of Chinese Materia Fifth Medical Center of Chinese PLA General HospitalBeijing 100039China Department of Health Statistics Faculty of Medical ServiceSecond Military Medical UniversityShanghai 200438China

Aristolochic acids(AAs) have long been considered as a potent carcinogen due to its nephrotoxicity. Aristolochic acid I(AAI) reacts with DNA to form covalent aristolactam(AL)-DNA adducts,leading to subsequent A to T transversion mutation, commonly referred as AA mutational signature. Previous research inferred that AAs were widely implicated in liver cancer throughout Asia. In this study, we explored whether AAs exposure was the main cause of liver cancer in the context of HBV infection in China's Mainland. Totally 1256 liver cancer samples were randomly retrieved from 3 medical centers and a refined bioanalytical method was used to detect AAI-DNA adducts. 5.10% of these samples could be identified as AAI positive exposure. Whole genome sequencing suggested 8.41% of 107 liver cancer patients exhibited the dominant AA mutational signature, indicating a relatively low overall AAI exposure rate. In animal models, long-term administration of AAI barely increased liver tumorigenesis in adult mice, opposite from its tumor-inducing role when subjected to infant mice. Furthermore, AAI induced dose-dependent accumulation of AA-DNA adduct in target organs in adult mice, with the most detected in kidney instead of liver. Taken together, our data indicate that AA exposure was not the major threat of liver cancer in adulthood.

关键词： Aristolochic acids(AAs) Mutational signature AA-DNA adduct Hepatocellular carcinoma(HCC) liver tumorigenesis Hepatitis B virus(HBV) Risk factors Tumor prevention

Plasma nitrogen fixation system with dual-loop enhancement for improved energy efficiency and its efficacy for lettuce cultivation

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Plasma Science and Technology 2024年第1期26卷 82-92页

作者：韩泽阳张梦雪张頔何欣井天军葛知轩李玉鸽朱童任云鸿仲崇山季方 College of Information and Electrical Engineering China Agricultural UniversityBeijing 100083People’s Republic of China College of Water Resources and Civil Engineering China Agricultural UniversityBeijing 100083People’s Republic of China Electric Power Research Institute State Grid Gansu Electric Power Company GansuLanzhou 730030People’s Republic of China

Plasma nitrogen fixation(PNF)has been emerging as a promising technology for greenhouse gasfree and renewable energy-based agriculture.Yet,most PNF studies seldom address practical application-specific issues.In this work,we present the development of a compact and automatic PNF system for on-site agricultural applications.The system utilized a gliding-arc discharge as the plasma source and employed a dual-loop design to generate NO_(x)from air and water under atmospheric conditions.Experimental results showed that the system with a dualloop design performs well in terms of energy costs and production rates.Optimal operational parameters for the system were determined through experimentation,resulting in an energy cost of 13.9 MJ mol^(-1)and an energy efficiency of 16 g kWh^(-1)for NO_(3)^(-)production,respectively.Moreover,the concentration of exhausted NO_(x)was below the emission standards.Soilless lettuce cultivation experiments demonstrated that NO_(x)^(-)produced by the PNF system could serve as liquid nitrate nitrogen fertilizer.Overall,our work demonstrates the potential of the developed PNF system for on-site application in the production of green-leaf vegetables.

关键词： plasma nitrogen fixation gliding arc soilless cultivation lettuce

科技论文视域下国际物理学科学中心与转移路径识别研究

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中国软科学 2024年第6期 54-65页

作者：李旺冉从敬黄文俊莫富传贾志轩武汉大学信息管理学院湖北武汉430072

综合科技多样化指数、科技专业化指数、社会网络分析法,构建国际物理学科学中心与转移路径识别模型,基于2003-2022年全球物理学领域代表性期刊论文数据,实现国际物理学科学中心及其转移路径识别。研究发现:(1)美国作为国际物理学科学中... 详细信息

综合科技多样化指数、科技专业化指数、社会网络分析法,构建国际物理学科学中心与转移路径识别模型,基于2003-2022年全球物理学领域代表性期刊论文数据,实现国际物理学科学中心及其转移路径识别。研究发现:(1)美国作为国际物理学科学中心具有绝对优势,但多中心格局或将成为大势所趋;(2)德国、英国、法国、瑞士、日本、中国等国家同美国的距离逐渐缩小,构成国际物理学研究的“一超多强”局面;(3)国际物理学科学中心呈现出从由美国向欧洲转移,再由欧洲向亚洲转移的态势。

关键词：科学中心科技论文转移路径