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融合非线性收敛因子与变异准反射学习的哈里斯鹰优化算法

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智能系统学报 2024年第3期19卷 738-748页

作者：宋美佳贾鹤鸣林志兴刘庆鑫三明学院网络中心福建三明365004 三明学院信息工程学院福建三明365004 海南大学计算机科学与技术学院海南海口570228

针对哈里斯鹰优化算法(Harris Hawks optimization,HHO)易早熟收敛、寻优精度低、收敛速度慢等问题,提出一种融合非线性收敛因子与变异准反射学习的哈里斯鹰优化算法(improved Harris Hawks optimization,IHHO)。首先,初始化阶段引入Cir... 详细信息

针对哈里斯鹰优化算法(Harris Hawks optimization,HHO)易早熟收敛、寻优精度低、收敛速度慢等问题,提出一种融合非线性收敛因子与变异准反射学习的哈里斯鹰优化算法(improved Harris Hawks optimization,IHHO)。首先,初始化阶段引入Circle混沌映射,提高初始化种群多样性和种群位置质量;其次,引入Sigmoid非线性收敛因子,平衡全局探索和局部开发能力;最后,针对HHO算法易陷入局部最优问题,提出变异准反射学习(quasi-reflection-based learning,QRBL)策略,提高种群活力,进一步提高算法局部收敛能力。仿真实验采用13个标准测试函数和1个经典工程问题对改进算法进行测试,结果表明改进算法收敛精度、收敛速度均有较大提高,适用于解决实际问题。

关键词：哈里斯鹰优化算法非线性收敛因子准反射学习准反向学习混沌映射工程问题元启发算法群智能

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基于信息熵和支持向量机的高校教师能力评价

三明学院学报 2024年第03期41卷 89-100页

作者：林志兴余建胡景肖香梅三明学院网络技术中心三明学院信息工程学院

针对现有的高校教师能力评价指标，提出一种人工智能算法的评价模型，以评估高校教师的教师的能力水平，促进教师教学质量的提升和学校整体教育质量的提高。采用基于信息熵和支持向量机等算法，建立了高校教师能力评价模型，利用信息熵... 详细信息

针对现有的高校教师能力评价指标，提出一种人工智能算法的评价模型，以评估高校教师的教师的能力水平，促进教师教学质量的提升和学校整体教育质量的提高。采用基于信息熵和支持向量机等算法，建立了高校教师能力评价模型，利用信息熵进行数据处理和特征选择，并运用支持向量机算法进行模型构建和评估。测试结果表明，基于信息熵和支持向量机算法的高校教师能力评价模型在评价过程和等级划分上具有较大的实用价值。该模型为高校教师的能力识别、管理和评价提供了有效的研究方法，有助于推进现有评价体系。

关键词：信息熵支持向量机高等教育能力评价

Switched-capacitor Based Seven-level Boost Inverter with a Reduced Number of Devices

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 381-391页

作者： Weijie lin Jun Zeng Bo Fu zhixing Yan Junfeng Liu School of Electric Power Engineering South China University of TechnologyGuangzhou 510641China WISDRI Engineering&Research Incorporation Limited Wuhan 430074China Department of Energy Aalborg UniversityAalborg 9220Denmark School of Automation Science and Engineering South China University of TechnologyGuangzhou 510641China

The conventional multilevel inverters(MLIs)have the disadvantages of numerous devices,incapacity of boost,unbalance for capacitor’s voltage,high complexity for control,and *** by this issue,a seven-level boost inverter(7LBI)based on a switched capacitor is presented for singlephase applications in this *** proposed 7LBI using only seven transistors can achieve seven output levels,1.5 voltage gain,and natural balance of capacitors’voltages without sensors or other auxiliary methods,which illustrates its suitability for the applications of renewable energy *** configuration of topology and operating principles are illustrated in *** natural balance of capacitors and capacitance calculations are deduced as ***,the comparative study is conducted for different types of *** results illustrate the merits of the proposed 7LBI with respect to reduced devices,lower voltage stress,and less power ***,a simulation for the proposed 7LBI with PWM modulation is realized based on the theoretical analysis;an experimental prototype is also implemented,verifying multilevel output,boost ability,natural balance for switched capacitors,and performance of transient response.

关键词： Multilevel inverters voltage gain natural balance renewable energy generation reduced number of elements

圣草酚对脓毒症致大鼠急性肾损伤的保护作用及机制研究

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中国中西医结合肾病杂志 2024年第7期25卷 574-577,I0001页

作者：林志星王珊珊庄亚萍林成寿麦勇猛海南医学院第一附属医院重症医学科海口571101

目的:探讨圣草酚对脓毒症急性肾损伤(SAKI)大鼠的影响,并阐明其作用机制。方法:采用盲肠结扎穿孔术建立脓毒症大鼠模型,将造模成功的大鼠随机分成模型组、圣草酚低剂量组、圣草酚高剂量组和圣草酚高剂量+核因子E2相关因子2(Nrf2)抑制剂... 详细信息

目的:探讨圣草酚对脓毒症急性肾损伤(SAKI)大鼠的影响,并阐明其作用机制。方法:采用盲肠结扎穿孔术建立脓毒症大鼠模型,将造模成功的大鼠随机分成模型组、圣草酚低剂量组、圣草酚高剂量组和圣草酚高剂量+核因子E2相关因子2(Nrf2)抑制剂组,另设置假手术组,每组10只。于造模前2 d开始给予圣草酚和Nrf2抑制剂预处理,持续干预3 d。术后24 h,生化法检测血清肌酐(Scr)、血尿素氮(BUN)水平;ELISA检测血清中IL-1β、IL-6浓度及肾组织中丙二醛(MDA)含量及超氧化物歧化酶(SOD)活性水平;HE染色观察肾组织病理学变化;荧光探针染色法检测大鼠肾组织活性氧(ROS)水平;Western blot检测大鼠肾脏组织中Nrf2和血红素加氧酶1(HO-1)蛋白表达水平。结果:与假手术组比较,模型组大鼠血清中Scr、BUN、IL-1β和IL-6水平显著升高(P0.05)。Nrf2抑制剂逆转了高剂量圣草酚对SAKI大鼠氧化应激和炎症反应的抑制作用(P<0.05)。结论:圣草酚预处理可抑制SAKI大鼠氧化应激和炎症水平,减轻肾脏损伤,其作用机制与激活Nrf2/HO-1信号通路有关。

关键词：圣草酚脓毒症急性肾损伤氧化应激炎症 Nrf2/HO-1信号通路

Fast Sentiment Analysis Algorithm Based on Double Model Fusion

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Computer Systems Science & Engineering 2021年第1期36卷 175-188页

作者： zhixing lin Like Wang Xiaoli Cui Yongxiang Gu Sanming University Network CenterSanming365004 College of Mathematics and Informatics Fujian Normal UniversityFuzhou350007China Chengdu Institute of Computer Applications Chinese Academy of SciencesChengdu610041China University of Chinese Academy of Sciences Beijing100049China Sichuan Rainbow Consulting&Software Co. Ltd.Chengdu610041China

Nowadays,as the number of textual data is exponentially increasing,sentiment analysis has become one of the most significant tasks in natural language processing(NLP)with increasing *** Chinese sentiment analysis algorithms cannot make full use of the order information in context and are inefficient in sentiment *** this paper,we systematically reviewed the classic and representative works in sentiment analysis and proposed a simple but efficient *** of all,FastText was trained to get the basic classification model,which can generate pre-trained word vectors as a ***,Bidirectional Long Short-Term Memory Network(Bi-LSTM)utilizes the generated word vectors for training and then merges with FastText to make comprehensive sentiment *** combining FastText and Bi-LSTM,we have developed a new fast sentiment analysis,called FAST-BiLSTM,which consistently achieves a balance between performance and *** particular,experimental results based on the real datasets demonstrate that our algorithm can effectively judge sentiments of users’comments,and is superior to the traditional algorithm in time efficiency,accuracy,recall and F1 criteria.

关键词： Sentiment analysis model fusion Bi-LSTM FastText

Neddylation is a novel therapeutic target for lupus by regulating double negative T cell homeostasis

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Signal Transduction and Targeted Therapy 2024年第2期9卷 738-750页

作者： Yun Zhang Lijun Du Chenxi Wang Zhangsheng Jiang Qingchi Duan Yiping Li Zhijun Xie zhixing He Yi Sun lin Huang Liwei Lu Chengping Wen Key Laboratory of Chinese medicine rheumatology of Zhejiang Province Research Institute of Chinese Medical Clinical Foundation and ImmunologyCollege of Basic Medical ScienceZhejiang Chinese Medical UniversityHangzhou 310053China Department of General Surgery Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Cancer Institute(Key Laboratory of Cancer Prevention and Intervention China National Ministry of Education)of the Second Affiliated Hospital and Institute of Translational MedicineZhejiang University School of MedicineHangzhou 310029China Cancer Center of Zhejiang University Hangzhou 310029China Department of Pathology and Shenzhen Institute of Research and Innovation The University of Hong KongHong KongChina Chongqing International Institute for Immunology Chongqing 400038China

Systemic lupus erythematosus(SLE),a severe autoimmune disorder,is characterized by systemic inflammatory response,autoantibody accumulation and damage to *** dysregulation of double-negative(DN)T cells is considered as a crucial commander during ***,a significant type of protein post-translational modification(PTM),has been well-proved to regulate T cell-mediated immune ***,the function of neddylation in SLE is still ***,we reported that neddylation inactivation with MLN4924,a specific inhibitor of NEDD8-activating enzyme E1(NAE1),or genetic abrogation of Ube2m in T cells decreased DN T cell accumulation and attenuated murine lupus *** investigations revealed that inactivation of neddylation blocked Bim ubiquitination degradation and maintained Bim level in DN T cells,contributing to the apoptosis of the accumulated DN T cells in lupus *** double knockout(KO)lupus-prone mice(Ube2m-/-Bim-/-lpr)were generated and results showed that loss of Bim reduced Ube2m deficiency-induced apoptosis in DN T cells and reversed the alleviated lupus *** findings identified that neddylation inactivation promoted Bim-mediated DN T cell apoptosis and attenuated lupus ***,we also found that in SLE patients,the proportion of DN T cells was raised and their apoptosis was ***,compared to healthy groups,SLE patients exhibited decreased Bim levels and elevated Cullin1 neddylation ***,the inhibition of neddylation induced Bim-dependent apoptosis of DN T cells isolated from SLE ***,our findings provide the direct evidence about the function of neddylation during lupus,suggesting a promising therapeutic approach for this disease.

关键词： inactivation double finding

Brain Pathology in COVID-19:Clinical Manifestations and Potential Mechanisms

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Neuroscience Bulletin 2024年第3期40卷 383-400页

作者： zhixing Xu Hui Wang Siya Jiang Jiao Teng Dongxu Zhou Zhong Chen Chengping Wen Zhenghao Xu First School of Clinical Medicine Zhejiang Chinese Medical UniversityHangzhou 310053China School of Pharmaceutical Sciences Zhejiang Chinese Medical UniversityHangzhou 310053China Second School of Clinical Medicine Zhejiang Chinese Medical UniversityHangzhou 310053China Afliated lin’an People’s Hospital of Hangzhou Medical College First People’s Hospital of Hangzhou Lin’an DistrictLin’anHangzhou 311300China School of Life Sciences Zhejiang Chinese Medical UniversityHangzhou 310053China Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province College of Pharmaceutical ScienceZhejiang Chinese Medical UniversityHangzhou 310053China Laboratory of Rheumatology and Institute of TCM Clinical Basic Medicine College of Basic Medical ScienceZhejiang Chinese Medical UniversityHangzhou 310053China

Neurological manifestations of coronavirus disease 2019(COVID-19)are less noticeable than the respiratory symptoms,but they may be associated with disability and mortality in *** though Omicron caused less severe disease than Delta,the incidence of neurological manifestations is *** than 30%of patients experienced“brain fog”,delirium,stroke,and cognitive impairment,and over half of these patients presented abnormal neuroimaging *** this review,we summarize current advances in the clinical findings of neurological manifestations in COVID-19 patients and compare them with those in patients with influenza *** also illustrate the structure and cellular invasion mechanisms of SARS-CoV-2 and describe the pathway for central SARS-CoV-2 *** addition,we discuss direct damage and other pathological conditions caused by SARS-CoV-2,such as an aberrant interferon response,cytokine storm,lymphopenia,and hypercoagulation,to provide treatment *** review may offer new insights into preventing or treating brain damage in COVID-19.

关键词： COVID-19 SARS-CoV-2 Brain Neurological pathology

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大跨屋盖结构风压脉动的非高斯特性

土木工程学报 2007年第4期40卷 1-5,12页

作者：孙瑛武岳林志兴沈世钊哈尔滨工业大学黑龙江哈尔滨150090 同济大学土木工程防灾国家重点实验室上海200092

借助刚性模型风洞动态同步测压试验,对大跨度平屋盖表面脉动风压的非高斯统计特性进行了系统研究。首先,根据测点风压时程及其概率密度分布,对具有非高斯分布特性的屋盖风压局部区域做出判断;然后,通过风压的时空间相关性,结合中心极限... 详细信息

借助刚性模型风洞动态同步测压试验,对大跨度平屋盖表面脉动风压的非高斯统计特性进行了系统研究。首先,根据测点风压时程及其概率密度分布,对具有非高斯分布特性的屋盖风压局部区域做出判断;然后,通过风压的时空间相关性,结合中心极限定理讨论局部呈现非高斯特性的原因;最后,基于测点风压的第三、四阶矩统计量对风压的非高斯特性进行描述,给出划分高斯非高斯区域的标准,并在此基础上对平屋盖进行了分区,通过区域划分揭示了不同区域的脉动风压形成机理,也体现出一些大跨屋盖结构不同于低矮房屋的流场特性。通过上述工作,增进了对大跨度屋盖表面风压分布特性的认识,为进一步探讨屋盖结构的抗风设计方法奠定了理论基础。

关键词：大跨屋盖结构动态同步测压试验脉动风压非高斯特性

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基于最优路径选择的网络感知服务组合算法

电讯技术 2022年第5期62卷 562-569页

作者：余建林志兴余高锋肖香梅刘孙发三明学院网络中心福建三明365004 三明学院信息工程学院福建三明365004 物联网应用福建省高校工程研究中心福建三明365004

为满足用户的性能需求及服务质量保障,针对复杂网络服务组合的特点和用户个性化的服务质量(Quality of Service,QoS)需求,研究了云环境下的网络感知服务组合问题,利用云服务和网络服务的QoS属性,提出了一种基于最优路径选择(Optimal Pat... 详细信息

为满足用户的性能需求及服务质量保障,针对复杂网络服务组合的特点和用户个性化的服务质量(Quality of Service,QoS)需求,研究了云环境下的网络感知服务组合问题,利用云服务和网络服务的QoS属性,提出了一种基于最优路径选择(Optimal Path Selection,OPS)的网络感知服务组合算法。该算法可以提升网络服务质量水平,改善用户体验质量。仿真结果表明,该算法在求解时间和质量两个方面都表现出了良好的性能,而且能动态适应用户复杂的需求,能够有效地解决云计算环境下的服务组合问题。

关键词：云计算网络感知服务组合最优路径选择云服务