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COMPUTER NUMERICAL SIMULATION OF MECHANICAL PROPERTIES OF TUNGSTEN HEAVY ALLOYS

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中国有色金属学会会刊：英文版 1999年第1期9卷 54-58页

作者： Huang, Jihua cao, zhiwei Zhou, Guo'an Univ of Science and Technology Beijing Beijing China

１ＩＮＴＲＯＤＵＣＴＩＯＮＴｕｎｇｓｔｅｎｈｅａｖｙａｌｏｙｓａｒｅｄｕａｌｐｈａｓｅｃｏｍｐｏｓｉｔｅｓｐｒｏｄｕｃｅｄｂｙｌｉｑｕｉｄｐｈａｓｅｓｉｎｔｅｒｉｎｇｏｆａｍｉｘｔｕｒｅｏｆ８０％～９７％ｔｕｎｇｓ... 详细信息

１ＩＮＴＲＯＤＵＣＴＩＯＮＴｕｎｇｓｔｅｎｈｅａｖｙａｌｏｙｓａｒｅｄｕａｌｐｈａｓｅｃｏｍｐｏｓｉｔｅｓｐｒｏｄｕｃｅｄｂｙｌｉｑｕｉｄｐｈａｓｅｓｉｎｔｅｒｉｎｇｏｆａｍｉｘｔｕｒｅｏｆ８０％～９７％ｔｕｎｇｓｔｅｎａｎｄａｓｍａｌａｍｏｕｎｔ...

关键词： tungsten heavy alloy mechanical property computer numerical simulation

Petri Net Based Metabolic Network Parameters Fitting with GPU Acceleration

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Chinese Journal of Chemistry 2011年第9期29卷 1805-1810页

作者： Gao, Jun Zhu, Ruixin Liu, Qi cao, zhiwei College of Life Science and Biotechnology Tongji University Shanghai 200092 China College oflnformation Engineering Shanghai Maritime University Shanghai 201306 China College of Pharmacy Liaoning University of Traditional Chinese Medicine Shenyang Liaoning 110032 China

Classical Petri net has been applied into biological analysis, especially as a qualitative model for biochemical pathways analysis, but lack of the ability for quantitative kinetic simulations. In our study, we presented an integra- tion work of the qualitative model--Petri nets with the quantitative approach-ordinary differential equations （ODEs） for the modeling and analysis of metabolic networks. As an application of our study, the computational modeling of arachidonic acid （AA） biochemical network was provided. A Petri net was set up to present the constraint-based dynamic simulations on AA metabolic network combined with the validated ODEs model. Furthermore, Graphics Processing Unit （GPU） was adopted to accelerate the calculation of kinetic parameters unavailable from experi- ments. Our results have indicated that the proposed simulation method was practicable and useful with GPU accel- eration, and provides new clues for the large-scale qualitative and quantitative models of biochemical networks.

关键词： Petri net ordinary differential equations metabolic network GPU kinetics

快速动态响应同步调相机转子引线断裂故障分析

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电网技术 2024年第9期48卷 3957-3964页

作者：王庆郭贤珊黄金军刘超李明韩晋思李斯特曹志伟国家电网有限公司北京市西城区100031 国家电网有限公司直流技术中心北京市西城区100052 国网内蒙古东部电力有限公司内蒙古自治区呼和浩特市010010 国网山东省电力公司电力科学研究院山东省济南市250003

大型调相机的安全稳定运行关乎着电网电压的稳定、动态无功支撑水平和新能源消纳能力。该文研究了一起实际的调相机转子引线断裂故障,综合现场检查、返厂解体检查、试验分析、故障复现实验及其他换流站同型号调相机的检查结果,发现转子... 详细信息

大型调相机的安全稳定运行关乎着电网电压的稳定、动态无功支撑水平和新能源消纳能力。该文研究了一起实际的调相机转子引线断裂故障,综合现场检查、返厂解体检查、试验分析、故障复现实验及其他换流站同型号调相机的检查结果,发现转子引线的设计及工艺方面存在缺陷,径向存在约4mm的悬空区域,加之长期运行磨损,最终导致调相机引线断裂烧熔触发跳机。从引线设计方案优化和实际运行工况着手,充分研判该型号调相机转子引线各段结构的可靠性及适用性,深入研究各种工况下的离心力及振动,保证引线及配套绝缘紧固连接,论证得出治理方案,为在运工程及后续新建机组安全可靠性奠定基础。

关键词：同步调相机转子引线断裂一点接地

Omics tools for the needle out of haystack?

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Journal of Genetics and Genomics 2018年第7期45卷 343-344页

作者： zhiwei cao Xiu-Jie Wang Shihua Zhang School of Life Sciences and Technology Tongji University Institute of Genetics and Developmental Biology Chinese Academy of Sciences Academy of Mathematics and Systems Science Chinese Academy of Sciences

With the rapid progress of omics technology, mining the needle of knowledge in the haystack of omics data has become extremely challenging and time-consuming. To meet the rising desire from biomedical communities, bioinformaticians worldwide have developed various tools to facilitate omics data analysis for a wide range of purposes.

关键词： In Omics tools for the needle out of haystack

Sequential Inverse Optimal Control of Discrete-Time Systems

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IEEE/CAA Journal of Automatica Sinica 2024年第3期11卷 608-621页

作者： Sheng cao zhiwei Luo Changqin Quan the Graduate School of System Informatics Kobe University Kobe 657-8501Japan

This paper presents a novel sequential inverse optimal control(SIOC)method for discrete-time systems,which calculates the unknown weight vectors of the cost function in real time using the input and output of an optimally controlled discrete-time *** proposed method overcomes the limitations of previous approaches by eliminating the need for the invertible Jacobian *** calculates the possible-solution spaces and their intersections sequentially until the dimension of the intersection space decreases to *** remaining one-dimensional vector of the possible-solution space’s intersection represents the SIOC *** paper presents clear conditions for convergence and addresses the issue of noisy data by clarifying the conditions for the singular values of the matrices that relate to the possible-solution *** effectiveness of the proposed method is demonstrated through simulation results.

关键词： Inverse optimal control promised calculation step sequential calculation

Study of drug function based on similarity of pathway fingerprint

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Protein & Cell 2012年第2期3卷 132-139页

作者： Hao Ye Kailin Tang Linlin Yang zhiwei cao Yixue Li State Key Laboratory of Bioreactor Engineering East China University of Science&TechnologyShanghai 200237China Shanghai Center for Bioinformation Technology Shanghai 200235China School of Life Science and Technology Tongji UniversityShanghai 200092China

Drugs sharing similar therapeutic function may not bind to the same group of ***,their targets may be involved in similar pathway profiles which are associated with certain pathological *** this study,pathway fingerprint was introduced to indicate the profile of significant pathways being influenced by the targets of *** drug−drug network was further constructed based on significant similarity of pathway *** this way,the functions of a drug may be hinted by the enriched therapeutic functions of its neighboring *** the test of 911 FDA approved drugs with more than one known target,471 drugs could be connected into networks.760 significant associations of drug−therapeutic function were generated,among which around 60%of them were supported by scientific literatures or ATC codes of drug functional ***,pathway fingerprints may be useful to further study on the potential function of known drugs,or the unknown function of new drugs.

关键词： pathway fingerprint drug−drug network therapeutic target function prediction

流域全局视角下多沙河流水库库容再生技术新探索

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人民黄河 2024年第9期46卷 32-36,41页

作者：谢遵党唐梅英曹智伟张雪才骆原张钰黄河勘测规划设计研究院有限公司河南郑州450003 水利部黄河流域水治理与水安全重点实验室(筹) 河南郑州450003

为系统性解决多沙河流已建水库淤积问题等,并为拟建水库冲淤设计提供理论和技术支撑,在调水调沙减淤的基础上,针对水库宽滩区大规模淤损库容再生的难题,研究提出多沙河流水库“冲淤过槽、驱沙入海”的库容再生新策略。在水力清淤技术的... 详细信息

为系统性解决多沙河流已建水库淤积问题等,并为拟建水库冲淤设计提供理论和技术支撑,在调水调沙减淤的基础上,针对水库宽滩区大规模淤损库容再生的难题,研究提出多沙河流水库“冲淤过槽、驱沙入海”的库容再生新策略。在水力清淤技术的基础上,为实现冲淤过槽和滩槽同治,探索借助工程措施及模块化装配式的装备分隔控导库区水流,增强水流自身动力和挟沙能力,将高滩淤沙冲入主槽和坝前排沙漏斗,并通过调水调沙带出水库,实现驱沙入海的目标。

关键词：多沙河流库容再生水力清淤工程措施及装备全局视角

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Maneuvering target tracking algorithm based on cubature Kalman filter with observation iterated update

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High Technology Letters 2015年第1期21卷 39-45页

作者：胡振涛 Fu Chunling cao zhiwei Li Congcong Instituteof Image Processing and Pattern Recognition Henan University School of Physics and Electronics Henan University

Reasonable selection and optimization of a filter used in model estimation for a multiple model structure is the key to improve tracking accuracy of maneuvering *** with the cubature Kalman filter with iterated observation update and the interacting multiple model method,a novel interacting multiple model algorithm based on the cubature Kalman filter with observation iterated update is ***,aiming to the structural features of cubature Kalman filter,the cubature Kalman filter with observation iterated update is constructed by the mechanism of iterated observation ***,the improved cubature Kalman filter is used as the model filter of interacting multiple model,and the stability and reliability of model identification and state estimation are effectively promoted by the optimization of model filtering *** the simulations,compared with classic improved interacting multiple model algorithms,the theoretical analysis and experimental results show the feasibility and validity of the proposed algorithm.

关键词： maneuvering target tracking nonlinear filtering cubature Kalman filter(CKF) interacting multiple model(IMM)

添加拉考沙胺、吡仑帕奈治疗儿童局灶性癫痫的临床疗效及对血清S100β、NSE水平的影响

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中国妇幼健康研究 2024年第9期35卷 49-56页

作者：曹志伟张润春王玉珍唐山市妇幼保健院小儿神经科河北唐山063000

目的探讨添加拉考沙胺、吡仑帕奈治疗儿童局灶性癫痫的临床疗效及对血清S-100β蛋白(S100β)、神经元特异性烯醇化酶(NSE)水平的影响。方法选择2019年12月至2022年12月唐山市妇幼保健院收治的122例初始单药治疗控制不佳的局灶性癫痫患... 详细信息

目的探讨添加拉考沙胺、吡仑帕奈治疗儿童局灶性癫痫的临床疗效及对血清S-100β蛋白(S100β)、神经元特异性烯醇化酶(NSE)水平的影响。方法选择2019年12月至2022年12月唐山市妇幼保健院收治的122例初始单药治疗控制不佳的局灶性癫痫患儿为研究对象。采用随机数字表法将患者分为拉考沙胺组(添加拉考沙胺治疗)和吡仑帕奈组(添加吡仑帕奈治疗),每组各61例。比较两组疗效,治疗前后智商、认知功能、血清S100β、NSE水平及治疗期间不良反应的差异。结果两组治疗1个月、3个月、6个月治疗应答率比较差异均无统计学意义(P>0.05);拉考沙胺组操作智商(PIQ)评分较治疗前增高(Z=2.775,P0.05);吡仑帕奈组易怒不良反应发生率高于拉考沙胺组,差异有统计学意义(P<0.05)。结论添加拉考沙胺和吡仑帕奈治疗儿童局灶性癫痫均可有效控制癫痫发作,降低血清S100β、NSE水平,对智力影响较小;吡仑帕奈对患儿认知功能和精神状态有一定负面影响。

关键词：儿童癫痫拉考沙胺吡仑帕奈 S-100β蛋白神经元特异性烯醇化酶