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SARS-CoV-2-specific CD4^(+)T cells are associated with long-term persistence of neutralizing antibodies

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Signal Transduction and Targeted Therapy 2022年第5期7卷 1773-1782页

作者： Zhongfang Wang Xiaoyun Yang Xinyue Mei Yumin Zhou zhiqiang tang Guichang Li Jiaying Zhong Mengqiu Yu Mingzhu Huang Xiaoling Su Bijia Lin Pengxing Cao Ji Yang Pixin Ran State Key Laboratory of Respiratory Disease&National Clinical Research Center for Respiratory Disease Guangzhou Institute of Respiratory HealthThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou Medical UniversityGuangzhouChina The Second People’s Hospital of Changde HunanChina School of mathematics and Statistics University of MelbourneMelbourneVICAustralia

Understanding the decay and maintenance of long-term SARS-CoV-2 neutralizing antibodies in infected or vaccinated people and how vaccines protect against other SARS-CoV-2 variants is critical for assessing public vaccination plans.Here,we measured different plasm antibody levels 2 and 12 months after disease onset,including anti-RBD,anti-N,total neutralizing antibodies,and two neutralizing-antibody clusters.We found that total neutralizing antibodies declined more slowly than total anti-RBD and anti-N IgG.

关键词： antibodies neutral assessing

固定床管式反应器内催化剂颗粒堆积与反应模拟

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石油化工 2024年第1期53卷 41-50页

作者：汤之强段晓霞中国石化北京化工研究院燕山分院北京102500 中国科学院过程工程研究所北京100190

采用数值模拟方法结合反应动力学,针对乙烯环氧化生产环氧乙烷的反应,考察了直径40.0mm的反应管中填充不同宏观尺寸的单孔或七孔催化剂颗粒时,反应器床层平均空隙率、堆密度以及单位床层高度压降、乙烯转化率、环氧乙烷选择性等参数的... 详细信息

采用数值模拟方法结合反应动力学,针对乙烯环氧化生产环氧乙烷的反应,考察了直径40.0mm的反应管中填充不同宏观尺寸的单孔或七孔催化剂颗粒时,反应器床层平均空隙率、堆密度以及单位床层高度压降、乙烯转化率、环氧乙烷选择性等参数的变化规律。模拟结果表明,对于七孔催化剂颗粒,随着催化剂外径的增加,床层平均空隙率大体呈现减小的趋势,这与单孔催化剂颗粒的变化趋势类似;而床层堆密度、乙烯转化率、环氧乙烷选择性均大体呈现增加的趋势,与单孔催化剂颗粒的变化趋势相反。

关键词：固定床反应器计算流体力学银催化剂乙烯环氧化环氧乙烷

Analysis of parental genetic diversity and its impact on grain yield and quality of japonica hybrid rice in northern China

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The Crop Journal 2022年第3期10卷 904-910页

作者： Hong Gao Zuobin Ma Yuanzheng Wang Manli Zhang Xianju Wang Changhua Wang zhiqiang tang Liying Zhang Liang Fu Na He Hui Wang Yongan Yin Yuanjun Bai Guomin Sui Wenjing Zheng Liaoning Rice Research Institute Shenyang 110101LiaoningChina Liaoning Academy of Agricultural Sciences Shenyang 110161LiaoningChina Xinjiang Tianye Group Ltd. Shihezi 832000XinjiangChina

The relationship between parental genetic differences and the quality and yield of japonica hybrid rice strongly influences japonica hybrid rice breeding.In this study,137 parental lines of japonica hybrid rice were genotyped using 8 K rice SNP-Chips to characterize their genetic diversity,population structure,and indica-genotype proportion.The genetic diversity of total parental lines averaged 0.264,with values of0.287 for restorer lines and 0.148 for the sterile lines.The introduction of indica lineage increased the genetic diversity of restorer lines relative to that of sterile lines.By model-based population structure analysis,the 137 lines were divided into 14 groups.According to the grouping results,eight restorer lines and five sterile lines were selected from different groups for cross breeding,yielding 40 japonica hybrid rice combinations(F1).Investigation of the yield and quality of these combinations showed that highyield combinations could be obtained by increasing parental genetic distance to 0.8–0.9,a result accomplished largely by the introduction of indica genomic components of restorer lines.To further improve grain quality,the genetic distance between parents should be reduced to 0.4–0.5,suggesting an indicagenotype proportion of 30%–40%for restorer lines.This study may provide a reference for breeding of japonica hybrid rice.

关键词： Japonica hybrid rice Genetic distance Indica-genotype proportion Heterosis

Investigation of the interior RC beam-column joints under monotonic antisymmetrical load

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Frontiers of Structural and Civil Engineering 2019年第6期13卷 1474-1494页

作者： Fei GAO zhiqiang tang Biao HU Junbo CHEN Hongping ZHU Jian MA School of Civil Engineering and Mechanics Huazhong University of Science and TechnologyWuhan 430074China Guangdong Provincial Key L aboratory of Durability for Marine Civil Engineering Shenzhen UniversityShenzhen 518060China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong Kong 999077China

The paper presents numerical findings of reinforced concrete interior beam-column joints under monotonic antisymmetrical load.The finite element models considered compression and tension damage were calibrated by test results in terms of the load-displacement,failure modes,and strains of longitudinal steel.The emphasis was put on studying the effects of hoop reinforcement ratio in joint core and the axial compression ratio on the responses of the joints.The results show that,in addition to the truss and strut-and-tie mechanisms,the confinement mechanism also existed in the joint core.A certain amount of stirrup is not only able to enhance the confinement in joint core,undertake a part of shear force and thus to increase the shear capacity,prevent the outward buckling of steel bars in column,improve the stress distribution in joint core,delay cracking and restrain the propagation of cracks,but also to increase the yield load,decrease the yield displacement of beam and improve the joint ductility.However,excessive horizontal stirrups contribute little to the joint performance.In a certain range,larger axial compression ratio is beneficial for the joint mechanical behavior,while it is negative when axial compression ratio is too large.

关键词： RC beam-column joint reinforcement ratio in joint core axial compression ratio finite element test

ESG理念下的上市公司绩效评价研究——以苏宁易购为例

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全国流通经济 2024年第3期 84-87页

作者：唐志强长江大学经济与管理学院湖北荆州434000

随着时代的发展,ESG(Environmental, Social and Governance)理念越来越受到人们的重视,ESG主要由环保、社会和公司治理三个领域所构成,为人们提供了一个更加全面的视角来分析企业价值。近年来,随着我国经济转型升级,社会经济逐渐向低... 详细信息

随着时代的发展,ESG(Environmental, Social and Governance)理念越来越受到人们的重视,ESG主要由环保、社会和公司治理三个领域所构成,为人们提供了一个更加全面的视角来分析企业价值。近年来,随着我国经济转型升级,社会经济逐渐向低碳绿色方向发展,ESG理念开始盛行,企业也从过去单纯追求经济效益,转变为追求经济效益与社会效益的协同发展,本文通过引入ESG评级,分析苏宁易购的ESG表现,从而促进企业实现可持续、高质量发展。

关键词： ESG 经济效益社会效益

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新郑市水系连通及水美乡村建设分析

河南水利与南水北调 2024年第5期53卷 20-21页

作者：唐志强新郑市水利局

农村水系对农村经济发展起到了重要的作用，在水美乡村要求提出后，需要了解农村建设的基本信息，获取基本数据，并且充分尊重自然条件，通过生态修复等方式，保证水资源承载力，为建设方案的落实提供基础条件。文章以新郑市水系连通以... 详细信息

农村水系对农村经济发展起到了重要的作用，在水美乡村要求提出后，需要了解农村建设的基本信息，获取基本数据，并且充分尊重自然条件，通过生态修复等方式，保证水资源承载力，为建设方案的落实提供基础条件。文章以新郑市水系连通以及水美乡村建设为案例进行分析，指出水系连通的技术要点，并且针对出现的问题进行全方位识别，希望增强水系空间形态修复能力，通过合理的调控技术，达到可持续发展目标。

关键词：水美乡村建设水系连通技术要点发展需求

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臭氧微纳米气泡-高级氧化耦合工艺深度处理工业废水

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水处理技术 2024年第5期50卷 130-135页

作者：唐志强张全党郑瑛玮毕春慧张弛王大伟中铁建生态环境有限公司重庆400711 河海大学材料科学与工程学院江苏常州213200 河海大学环境学院浅水湖泊综合治理与资源开发教育部重点实验室江苏南京210098

工业废水具有水量大、水质复杂、污染物浓度高、毒性强、腐蚀性强及难降解等特点,传统处理技术难以取得良好效果。本研究首次将压力强化臭氧微纳米气泡与高级氧化工艺耦合,构建了新型压力强化臭氧微纳米气泡—高级氧化耦合工艺反应器。... 详细信息

工业废水具有水量大、水质复杂、污染物浓度高、毒性强、腐蚀性强及难降解等特点,传统处理技术难以取得良好效果。本研究首次将压力强化臭氧微纳米气泡与高级氧化工艺耦合,构建了新型压力强化臭氧微纳米气泡—高级氧化耦合工艺反应器。从污染物去除率、不同条件下反应器内气泡粒径差异、液体中臭氧浓度、溶解氧浓度及尾气中臭氧浓度等多角度明确了反应器的最优参数为0.3 Mpa的出水压力及0.5 L/min的进气流量,明确了反应器的最佳使用温度范围为15℃至25℃。并从活性自由基的角度阐明了压力强化臭氧微纳米气泡耦合高级氧化工艺去除水中难降解污染物过程中的机制。本研究的研究成果有望为实现控制工业废水处理成本、提高COD去除率和矿化难降解污染物,为臭氧微纳米气泡技术的高效运行及安装优化提供理论依据和技术支持。

关键词：压力强化臭氧微纳米气泡高级氧化反应器最优参数水质参数影响活性自由基

SNP-based QTL mapping for panicle traits in the japonica super rice cultivar Liaoxing 1

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The Crop Journal 2020年第5期8卷 769-780页

作者： Mingzhu Zhao Zuobin Ma Lili Wang zhiqiang tang Ting Mao Chuanbin Liang Hong Gao Liying Zhang Na He Liang Fu Changhua Wang Guomin Sui Wenjing Zheng Institute of Rice Research Liaoning Academy of Agricultural SciencesShenyang 110000LiaoningChina Institute of Rice Research Shenyang Agricultural UniversityShenyang 110161LiaoningChina Liaoning Province Saline and Alkaline Land Utilization and Research Institute Panjin 124010LiaoningChina

Panicle traits directly associated with yield are a target of selection in rice breeding.Although abundant QTL for panicle traits have been identified,there is little information about the genetic basis of panicle traits in japonica super rice(JSR)cultivars.In this study,we identified QTL for panicle traits in three environments using a population of recombinant inbred lines(RILs)derived from the JSR cultivar Liaoxing 1.A total of 197 RILs were genotyped with 285 polymorphic SNP markers.Phenotypic data and best linear unbiased prediction(BLUP)value of primary branch number(BNP),secondary branch number(BNS),grain number on primary branch(GNP),grain number on secondary branch(GNS),grain number per panicle(GN),panicle length(PL)and grain density(GD)were used for QTL mapping.A total of 105 QTL for seven panicle traits were detected in single environments using their BLUP values.Individual QTL explained 0.51%–52.22%of the phenotypic variation.Of the 105,49 were also detected by joint multi-environment analyses.Five stable QTL:qGD9,qPL9,qGNP9,qGN6,and qBNS6.2 were identified in multiple environments.qGD9,qGNP9,and qPL9,co-localizing on chromosome 9,likely correspond to the known gene DEP1.Importantly,qGN6 and qBNS6.2 in a co-localization region were identified as novel QTL,and their Liaoxing 1 alleles had a positive effect.Several RILs with the QTL allele combinations qGD9/qPL9/qGNP9 and qGN6/qBNS6.2 showed greater GN.Further investigation of the putative gene underlying qGN6/qBNS6.2 would shed light on the molecular mechanism of JSR.

关键词： cultivar panicle effect.

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溶剂发泡对天然气净化装置的影响分析

辽宁化工 2024年第6期53卷 962-966页

作者：汤俊罗曼柔唐志强张晶晶林戈中石化广元天然气净化有限公司四川广元628400

甲基二乙醇胺(MDEA)是天然气净化工业中常用的脱硫剂,溶剂发泡常见于该类脱硫剂,会影响装置平稳生产,严重时造成冲塔事故。分析了溶剂发泡原因,对装置的影响及原理,并对消泡后的操作给出建议。结果表明:溶剂发泡主要是泡沫的累积,在体... 详细信息

甲基二乙醇胺(MDEA)是天然气净化工业中常用的脱硫剂,溶剂发泡常见于该类脱硫剂,会影响装置平稳生产,严重时造成冲塔事故。分析了溶剂发泡原因,对装置的影响及原理,并对消泡后的操作给出建议。结果表明:溶剂发泡主要是泡沫的累积,在体系中泡沫生成容易,生成速度大于消泡速度;发泡后,溶剂对羰基硫的吸收能力增强,湿气中羰基硫质量分数下降29.6%,闪蒸罐液位会不断上涨,再生塔液位下降,塔顶温度平均上升3.14℃,回流量增加436kg·h^(-1);消泡后装置短时波动较大,应注意液位控制,根据酸性气量调整克劳斯炉配风。

关键词：天然气净化 MDEA 溶剂发泡吸收酸性气

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