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Adaptive Fourier Decomposition of the First Three SARS-CoV-2 Infection Waves with Epidemic Intervention—London,UK,2020-2022

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China CDC weekly 2024年第21期6卷 478-486,I0006-I0008页

作者： Zige Liu Guibin Lu Cheokieng Vong zhiqi zeng Wei He Zhijie Lin Cuiyun Lin Kaichin Hsieh Zifeng Yang Arlindo L.Oliveira Chitin Hon Department of Engineering Science Faculty of Innovation EngineeringMacao University of Science and TechnologyMacao SARChina Queen Ethelburga’s Collegiate Thorpe Underwood EstateYorkUK State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory HealthThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina Respiratory Disease AI Laboratory on Epidemic and Medical Big Data Instrument Applications Department of Engineering ScienceFaculty of Innovation EngineeringMacao University of Science and TechnologyMacao SARChina Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases KingMed School of Laboratory MedicineGuangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina Faculty of Innovation Engineering School of Computer Science and EngineeringMacao University of Science and TechnologyMacao SARChina University College London UCL Faculty of Engineering SciencesLondonUK Guangzhou Laboratory Guangzhou CityGuangdong ProvinceChina Instituto de Engenharia de Sistemas e Computadores:Investigação e Desenvolvimento em Lisboa LisboaPortugal Instituto Superior Técnico Universidade de LisboaLisboaPortugal

Background:This study provides a detailed analysis of the daily fluctuations in coronavirus disease 2019(COVID-19)case numbers in London from January 31,2020 to February 24,*** primary objective was to enhance understanding of the interactions among government pandemic responses,viral mutations,and the subsequent changes in COVID-19 case ***:We employed the adaptive Fourier decomposition(AFD)method to analyze diurnal changes and further segmented the AFD into novel multi-component groups consisting of one to three *** restructured components were rigorously evaluated using Pearson correlation,and their effectiveness was compared with other signal analysis *** study introduced a novel approach to differentiate individual components across various time-frequency scales using basis decomposition ***:Analysis of London’s daily COVID-19 data using AFD revealed a strong correlation between the“stay at home”directive and high-frequency components during the first epidemic *** indicates the need for sustained implementation of vaccination policies to maintain their ***:The AFD component method provides a comprehensive analysis of the immediate and prolonged impact of governmental policies on the spread of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).This robust tool has proven invaluable for analyzing COVID-19 pandemic data,offering critical insights that guide the formulation of future preventive and public health strategies.

关键词： offering sustained London

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The Impact of Medical Resources and Oral Antiviral Drugs on SARS-CoV-2 Mortality—Hong Kong SAR,China,2022

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China CDC weekly 2024年第21期6卷 469-477,I0001-I0005页

作者： zhiqi zeng Jingyi Liang Zhijie Lin Wenda Guan Wei He Qianying Li Lixi Liang Weiqi Pan Zige Liu Guibin Lu Xiaoyan Deng Eric HY Lau Chitin Hon Zifeng Yang Guangzhou key laboratory for clinical rapid diagnosis and early warning of infectious diseases KingMed School of Laboratory MedicineGuangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina Macao Institute of Systems Engineering Macao University of Science and TechnologyMacao SARChina Respiratory Disease AI Laboratory on Epidemic Intelligence and Medical Big Data Instrument Applications Faculty of Innovative EngineeringMacao University of Science and TechnologyMacao SARChina State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory Healththe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina School of Public Health The University of Hong KongHong Kong SARChina Laboratory of Data Discovery for Health Hong Kong SARChina Guangzhou Laboratory Guangzhou CityGuangdong ProvinceChina

Introduction:The Omicron variant of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)demonstrates increased transmissibility compared to earlier strains,contributing to a significant number of fatalities in Hong Kong Special Administrative Region(HKSAR),*** medical resources and medications are essential in mitigating these *** study evaluates the effects of supplementary resources from the Chinese mainland during the fifth wave of the pandemic in ***:Vector autoregression(VAR)was employed to analyze data from the Oxford coronavirus disease 2019(COVID-19)Government Response Tracker to assess the effectiveness of control measures during five waves of the pandemic in ***,a transmission dynamics model was created to investigate the influence of supplementary medical resources from the Chinese mainland and oral medications on ***:In the initial four waves,workplace closures,restrictions on public events,international travel bans,and shielding the elderly significantly influenced pandemic ***,during the fifth wave,these measures showed no notable *** comparing a situation without extra medical resources or COVID-19 oral medication,there was a 17.7%decrease in COVID-19 fatalities with mainland medical resources and an additional 10.2%reduction with oral ***,they contributed to a 26.6%decline in ***:With the rapid spread of the virus,regional reallocation of medical resources may reduce mortality even when the local healthcare system is overstretched.

关键词： mainland Impact travel

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The 2022 Extreme Heatwave in Shanghai,Lower Reaches of the Yangtze River Valley:Combined Influences of Multiscale Variabilities

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Advances in Atmospheric Sciences 2024年第4期41卷 593-607页

作者： Ping LIANG zhiqi ZHANG Yihui DING zeng-Zhen HU Qi CHEN Key Laboratory of Cities’Mitigation and Adaptation to Climate Change in Shanghai Shanghai Regional Climate CenterChina Meteorological AdministrationShanghai 200030China National Climate Center China Meteorological AdministrationBeijing 100081China Climate Prediction Center NCEP/NWS/NOAACollege ParkMD 20740USA

In the summer of 2022,China(especially the Yangtze River Valley,YRV)suffered its strongest heatwave(HW)event since *** this study,we examined the influences of multiscale variabilities on the 2022 extreme HW in the lower reaches of the YRV,focusing on the city of *** found that about 1/3 of the 2022 HW days in Shanghai can be attributed to the long-term warming trend of global *** mid-summer of 2022,an enhanced western Pacific subtropical high(WPSH)and anomalous double blockings over the Ural Mountains and Sea of Okhotsk,respectively,were associated with the persistently anomalous high pressure over the YRV,leading to the extreme *** Pacific Decadal Oscillation played a major role in the anomalous blocking pattern associated with the HW at the decadal time ***,the positive phase of the Atlantic Multidecadal Oscillation may have contributed to regulating the formation of the double-blocking *** warming of both the warm pool of the western Pacific and tropical North Atlantic at the interannual time scale may also have favored the persistency of the double blocking and the anomalously strong *** the subseasonal time scale,the anomalously frequent phases 2-5 of the canonical northward propagating variability of boreal summer intraseasonal oscillation associated with the anomalous propagation of a weak Madden-Julian Oscillation suppressed the convection over the YRV and also contributed to the ***,the 2022 extreme HW originated from multiscale forcing including both the climate warming trend and air-sea interaction at multiple time scales.

关键词： extreme heatwave multiscale variability air-sea interaction warming trend Yangtze River Valley Shanghai

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Antigenic Drift of the Hemagglutinin from an Influenza A(H1N1) pdm09 Clinical Isolate Increases its Pathogenicity In Vitro

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Virologica Sinica 2021年第5期36卷 1220-1227页

作者： Lei Xing Yunbo Chen Boqian Chen Ling Bu Ying Liu zhiqi zeng Wenda Guan Qigao Chen Yongping Lin Kun Qin Honglin Chen Xilong Deng Xinhua Wang Wenjun Song State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory HealthThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510180China Artemisinin Research Center Guangzhou University of Chinese MedicineGuangzhou 510405China Institute of Integration of Traditional and Western Medicine The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510180China Intensive Care Unit Guangzhou No.8 People’s Hospital of Guangzhou Medical UniversityGuangzhou 510060China State Key Laboratory of Emerging Infectious Diseases Department of MicrobiologyThe University of Hong KongHong Kong SARChina China CDC National Institute for Viral Disease Control and PreventionBeijing 100052China

The influenza A(H1 N1)pdm09 virus emerged in 2009 and has been continuously circulating in humans for over ten ***,we analyzed a clinical influenza A(H1 N1)pdm09-infected patient case hospitalized for two months in Guangdong(from December 14,2019 to February 15,2020).This isolate,named A/Guangdong/LCF/2019(LCF/19),was genetically sequenced,rescued by reverse genetics,and phylogenetically analyzed in the context of other relevant pdm09 *** with earlier isolates,this pdm09 virus’s genetic sequence contains four substitutions,S186 P,T188 I,D190 A,and Q192 E,of the hemagglutinin(HA)segment at position 186–192(H3 numbering)in the epitope Sb,and two of which are located at the *** analysis indicated that the epitope Sb started undergoing a rapid antigenic change *** characterize the pathogenicity of this novel substitution motif,a panel of reassortant viruses containing the LCF/2019 HA segment or the chimeric HA segment with the four substitutions were *** growth data revealed that the reassortant viruses,including the LCF/2019 with the PTIAAQE substitution,propagated faster than those rescued ones having the STTADQQ motif in the epitope Sb in Madin-Darby Canine Kidney(MDCK)*** HI test showed that the binding activity of escape mutant to 2018 pdm09 sera was weaker than GLW/2018,suggesting that old vaccines might not effectively protect people from *** to the difference in the selection of vaccine strains,people vaccinated in the southern hemisphere could still suffer a severe infection if infected with this antigenic drift pdm09 virus.

关键词： HA antigenic drift Influenza A(H1N1)pdm09 virus HA epitope Sb

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Deep Analysis of Free-cutting Phase and Its Distribution in Japanese SF20T Pen Tip Steel

Deep Analysis of Free-cutting Phase and Its Distribution in ...

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作者： Panpan Zhang zhiqi zeng Tian Fan Ping Shen Jianxun Fu Center for Advanced Solidification Technology （CAST） School of Materials Science and Engineering Shanghai University

This paper aims at investigating the existence state of free-cutting phase in Japan SF20 T free-cutting stainless steel（one of the most widely used pen tip steel）. By using the devices of an optical microscope（OM）, a scanning electron microscope（SEM）, electrolytic etching, and Vickers hardness meter, the quantity, composition, shape, size, distribution of the free-cutting phase in the steel and the change of hardness of steel were analysed and characterized, strive to find out the reason of the performance of SF20 T steel is far superior to that of other countries’ pen tip steel. The results show that the morphologies of inclusions in the steel were mostly in spindle shape, and their distributions were dispersed and quite uniform. The free-cutting phases, MnS in spindle, Pb, and MnTe, were beneficial to enhancing the cutting performance of the steel. In contrast to domestic materials, the distribution of inclusions in the Japanese steel was more uniform, thereby providing key significance for production of penmaking and steelmaking in domestic plants.

关键词： pen tip steel free-cutting phase morphology hardness

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Crucial control measures to contain China's first Delta variant outbreak

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National Science Review 2022年第4期9卷 41-50页

作者： Lei Luo Zifeng Yang Jingyi Liang Yu Ma Hui Wang Chitin Hon Mei Jiang Zhengshi Lin Wenda Guan Zhitong Mai Yongming Li Kailin Mai zhiqi zeng Chuanmeizi Tu Jian Song Bin Liu Yong Liu Jianfeng He Huiyuan Li Bosheng Li Hang Dong Yutian Miao Shujun Fan Lirui Fan Xingyi Liang Ke Li Chun Chen Huihong Deng Zhicong Yang Nanshan Zhong Institute of Public Health Guangzhou Medical University & Guangzhou Center for Disease Control and Prevention Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases Department of Urban and Rural Planning Shunde Urban and Rural Planning Information Research Center Guangzhou Laboratory Bio-Island State Key Laboratory of Quality Research in Chinese Medicine Macau Institute for Applied Research in Medicine and HealthMacau University of Science and Technology Kingmed Virology Diagnostic & Translational Center Guangzhou Kingmed Center for Clinical Laboratory Co.Ltd State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory Healththe First Affiliated Hospital of Guangzhou Medical University Guangdong Center for Disease Control and Prevention Macau Institute of Systems Engineering Macau University of Science and Technology

The SARS-C oV-2 B.1.617.2(Delta) variant flared up in late May in Guangzhou,*** characteristics of Delta variant were analysed for 153 confirmed cases and two complete transmission chains with seven generations were fully presented.A rapid transmission occurred in five generations within10 *** basic reproduction number(R) was 3.60(95% confidence interval:2.50-5.30).After redefining the concept of close contact,the proportion of confirmed cases discovered from close contacts increased from 43% to 100%.With the usage of a yellow health code,the potential exposed individuals were self-motivated to take a nucleic acid test and regained public access with a negative testing *** the massive requirement of screening,novel facilities like makeshift inflatable laboratories were promptly set up as a vital supplement and 17 cases were found,with 1 *** dynamic adjustment of these three interventions resulted in the decline of Rt from 5.00 to 1.00 within 9 *** breaking the transmission chain and eliminating the transmission source through extending the scope of the close-contact tracing,health-code usage and mass testing,the Guangzhou D elta epidemic was effectively contained.

关键词： COVID-19 public health control measure close contact mass testing

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Synergistic oxidation-reforming of biomass for high quality syngas production based on a bifunctional catalyst

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Green Carbon 2024年第1期2卷 118-123页

作者： Tao He Dan Zhang Wenqing Chen zeng Liu Ruidong Zhao Jianqing Li Jingli Wu zhiqi Wang Jinhu Wu CAS Key Laboratory of Biofuels Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101China Shandong Energy Institute Qingdao 266101China Qingdao New Energy Shandong Laboratory Qingdao 266101China University of Chinese Academy of Sciences Beijing 100049China

Conventional O_(2)gasification for low-rank biomass/sludge conversion is prone to high CO_(2)concentrations in the syngas because of its high O content and low calorific *** study establishes a synergistic oxidationreforming reaction route for the conversion of low-rank carbon-containing resources into high-quality *** efficient oxidation-reforming reaction is based on the bifunctional catalyst NiO-Fe_(2)O_(3)/Al_(2)O_(3),which includes Fe_(2)O_(3) oxidation sites and NiO reforming *** temperature-programmed reduction,together with X-ray diffraction and X-ray photoelectron spectroscopy experiments,demonstrated that the two functional active sites have strong interactions with the support,leading to efficient cooperation between the oxidation reaction and reforming reaction with regards to both the reaction sequence and C/H/O element *** produced from biomass/sludge based on oxidation-reforming reactions has an extremely low CO_(2)concentration of approximately 3%,and the valid gas(CO,H_(2))concentration exceeds 95%.The valid gas yield of walnut shell reached 1452.9 mL/g,the total gas yield was 1507.2 mL/g,and the H_(2)/CO ratio was 1.02,which are all very close to the theoretical maximum values of 1553.1 mL/g and 1.01,respectively,demonstrating that the inherent CO_(2)/H_(2)O along with CH4/tar species were efficiently converted to H_(2)and CO through oxidation-reforming *** a 60-cycle test,NiO-Fe_(2)O_(3)/Al_(2)O_(3) exhibited good redox stability.

关键词： Biomass Syngas Oxidation-reforming Bifunctional Catalyst

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促进数字公平:美国公共图书馆的举措与启示

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图书与情报 2024年第1期 87-98页

作者：曾粤亮汪莘桐黄芷琪华中师范大学信息管理学院湖北武汉430079 湖北省数据治理与智能决策研究中心湖北武汉430079

公共图书馆是社会数字化转型中促进数字公平的重要力量。文章结合文献和案例调查,剖析美国公共图书馆促进数字公平的背景,在《2020年美国公共图书馆技术调查》《充分利用图书馆资源以实现全民数字公平》报告基础上结合其他文献与案例归... 详细信息

公共图书馆是社会数字化转型中促进数字公平的重要力量。文章结合文献和案例调查,剖析美国公共图书馆促进数字公平的背景,在《2020年美国公共图书馆技术调查》《充分利用图书馆资源以实现全民数字公平》报告基础上结合其他文献与案例归纳举措。研究发现美国公共图书馆促进数字公平的举措主要包括:馆内外技术资源供给、网络基础设施建设、线上为用户提供技术支持服务或资源、数字素养与技能培训。对我国公共图书馆的启示包括:增强网络与数字技术设施的可及性、以用户需求为导向丰富线上数字资源类型与服务形式、重视弱势群体数字素养教育和计算机技能培训、通过专门项目缩小城乡数字鸿沟、寻求外部多元合作。

关键词：公共图书馆数字公平数字鸿沟数字不平等美国公共图书馆

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含镁非调质钢中尖晶石转变机制研究

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钢铁钒钛 2021年第5期42卷 164-169页

作者：李志伟曾志崎谢剑波田钱仁付建勋先进凝固技术中心上海大学材料科学与工程学院上海200072 上海宝信软件股份有限公司信息服务事业本部上海200072

基于镁改质非调质钢中夹杂物的形成特征规律,通过计算MgAl_(2)O_(4)与MnS间的错配度以揭示MnS在MgAl_(2)O_(4)上的最佳生长面,以及计算MgAl_(2)O_(4)颗粒之间的主要作用力。结果表明,不添加Mg时,铸坯边部的硫化物主要呈链状沿晶界析出,... 详细信息

基于镁改质非调质钢中夹杂物的形成特征规律,通过计算MgAl_(2)O_(4)与MnS间的错配度以揭示MnS在MgAl_(2)O_(4)上的最佳生长面,以及计算MgAl_(2)O_(4)颗粒之间的主要作用力。结果表明,不添加Mg时,铸坯边部的硫化物主要呈链状沿晶界析出,铸坯中心的硫化物主要呈杆状或角状。当钢中添加Mg后,边部和中心处夹杂物主要呈球状或链状,且尺寸较小。Mg改质后铸坯边部和中心处的夹杂物尺寸均降低,中心区域夹杂物的平均面积由14.33μm^(2)降低到8.78μm^(2),边部区域夹杂物的平均面积由3.17μm^(2)降低到2.99μm^(2),Mg的加入使钢中夹杂物等效面积降低。MnS晶格的(110)晶面和MgAl_(2)O_(4)的(110)晶面晶格错配度为7.65%。腔桥力是MgAl_(2)O_(4)颗粒黏附的作用力,腔桥力约为1×10^(-8)N。

关键词：非调质钢镁 MgAl_(2)O_(4)颗粒错配度

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镁系易切削钢中夹杂物分析

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钢铁钒钛 2021年第2期42卷 179-187,192页

作者：朱强斌李杰邓向阳田钱仁曾志崎付建勋上海大学材料基因组工程研究院上海200444 上海大学材料科学与工程学院上海200444 中天钢铁集团有限公司江苏常州213000

为了探究Mg处理对易切削钢中夹杂物的影响,以1144高硫易切削钢为试验钢种,采用金相和能谱仪等手段研究了Mg处理对1144易切削钢中夹杂物的形态、尺寸分布和夹杂物成分的影响。结果表明:在易切削钢铸坯中,Mg处理使得易切削钢铸坯硫化物夹... 详细信息

为了探究Mg处理对易切削钢中夹杂物的影响,以1144高硫易切削钢为试验钢种,采用金相和能谱仪等手段研究了Mg处理对1144易切削钢中夹杂物的形态、尺寸分布和夹杂物成分的影响。结果表明:在易切削钢铸坯中,Mg处理使得易切削钢铸坯硫化物夹杂由Ⅱ类向Ⅲ类、Ⅰ类转变,分布更为均匀,同时使得复合硫化锰夹杂物比例提升。在轧材中,使得钢中夹杂物球化,并且钢中硫化锰夹杂物的尺寸和分布也得到了较好的改善,同时,Mg处理能够有效提高易切削钢的切削加工性能。

关键词：易切削钢 MnS 夹杂物 Mg处理

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