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解卡和爆破方法在兰州地热井卡钻事故处理中的应用

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地质装备 2023年第5期24卷 45-48页

作者：田少雄吴治南刘仕娟河北省煤田地质局第二地质队(河北省干热岩研究中心) 河北邢台054001

兰州地热井工程钻遇地层有第四系、第三系、松散层、黏土层、泥岩层和页岩层。由于上述水敏性岩层钻进过程遇水易出现膨胀、缩径和剥落等问题,严重威胁井内安全。针对兰州地热井水敏性地层易发生粘吸卡钻问题,尝试多种解卡方法,均未成... 详细信息

兰州地热井工程钻遇地层有第四系、第三系、松散层、黏土层、泥岩层和页岩层。由于上述水敏性岩层钻进过程遇水易出现膨胀、缩径和剥落等问题,严重威胁井内安全。针对兰州地热井水敏性地层易发生粘吸卡钻问题,尝试多种解卡方法,均未成功解卡。爆破松扣后下套扫打捞、磨铣落鱼失败,最后定向侧钻,不再处理该井事故。通过分析整个事故处理过程,对类似地层提供一定的借鉴和指导价值。

关键词：卡钻事故分析预防措施

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左髂外静脉超声参数对左髂静脉压迫综合征的补充诊断价值

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中国超声医学杂志 2023年第9期39卷 1037-1041页

作者：陈静辉吴志南张望金黄汝哨邱思花张华炜龚亮福建医科大学附属龙岩第一医院超声科福建医科大学附属龙岩第一医院心胸血管外科

目的探讨左髂外静脉超声参数对左髂静脉压迫综合征(IVCS)的补充诊断价值。方法选取116例拟行大隐静脉曲张手术治疗的患者，根据术前下肢深静脉造影结果将左髂静脉受压>50%且有侧支循环形成的患者记为左IVCS组，共71例(包括左IVCS合并... 详细信息

目的探讨左髂外静脉超声参数对左髂静脉压迫综合征(IVCS)的补充诊断价值。方法选取116例拟行大隐静脉曲张手术治疗的患者，根据术前下肢深静脉造影结果将左髂静脉受压>50%且有侧支循环形成的患者记为左IVCS组，共71例(包括左IVCS合并双下肢静脉曲张组36例、左IVCS合并左下肢静脉曲张组35例);将髂静脉受压<50%的患者记为非IVCS组，共45例(包括非IVCS合并双下肢静脉曲张组17例、非IVCS合并一侧下肢静脉曲张组28例);根据双下肢静脉曲张情况左IVCS组与非IVCS组再细分小组，并分别进行成组比较。结果 (1)在双下肢静脉曲张患者中，左IVCS与非IVCS患者综合Logistic回归分析及受试者工作特征(ROC)曲线分析结果，平躺内径指数比、内径变化指数比倒数及血流速度变化指数比倒数对IVCS有诊断价值(P<0.05),其曲线下面积分别为0.768、0.773及0.773,截点值分别为0.682、1.952及0.609,灵敏度分别为58.1%、63.6%及92.4%,特异度分别为80.8%、93.1%及55.6%;(2)左IVCS合并左下肢静脉曲张组与非IVCS合并一侧下肢静脉曲张组相比，综合Logistic回归分析及ROC曲线分析结果，仅平躺内径指数比对IVCS有诊断价值(P<0.05),其曲线下面积、截点值、灵敏度及特异度分别为0.725、0.646、76.2%及64.7%。结论对于静脉曲张的患者，当腹部髂总静脉超声检查条件差时，髂外静脉的超声参数对补充诊断IVCS有指导意义，可提高诊断率。

关键词：超声检查髂静脉压迫综合征静脉曲张

人卵泡液中肾素-血管紧张素系统与年龄、卵巢功能及IVF实验室结局的相关性研究

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中华生殖与避孕杂志 2024年第1期44卷 59-66页

作者：魏仑骆超伯乐周安稳吴志南陆宣平占雷高莎莎钱菲茅彩萍苏州大学附属第一医院生殖医学中心苏州215006

目的探索人卵泡液(human follicular fluid,hFF)中肾素-血管紧张素系统(renin-angiotensin system,RAS)与年龄、卵巢功能及体外受精(in vitro fertilization,IVF)实验室结局的相关关系。方法设计非干预的观察性研究,收集2021年1月至2022年2月期间在苏州大学附属第一医院生殖医学中心单纯因男方因素接受IVF女性患者的hFF及不包含个人身份的病历信息。采用酶联免疫吸附试验试剂盒检测hFF中的肾素、血管紧张素转换酶(angiotensin converting enzyme,ACE)、ACE2、血管紧张素(angiotensin,Ang)Ⅱ和Ang 1-7的水平。一元线性回归用于RAS组分与年龄的相关性分析,多元线性回归用于RAS组分与卵巢功能及IVF实验室结局的相关性分析。结果①共获139例可分析样本。②年龄与肾素(Pearson's r=-0.3133,P0.05)。③基础卵泡刺激素与年龄(β=0.636,P0.05)。④获卵数与肾素(β=0.146,P=0.014)、AngⅡ(β=0.113,P=0.034)和Ang1-7(β=0.185,P=0.002)呈正相关,与年龄(β=-0.717,P<0.001)呈负相关;MⅡ卵成熟率与AngⅡ(β=0.207,P=0.019)和Ang1-7(β=0.217,P=0.026)呈正相关,与年龄(β=-0.518,P<0.001)呈负相关;双原核胚胎率、可移植胚胎率、优质胚胎率仅与年龄呈负相关(均P<0.05)。结论卵泡局部RAS受到年龄影响,且与卵巢功能及IVF实验室结局存在一定关系。

关键词：受精,体外卵泡液肾素-血管紧张素系统年龄卵巢

Effect of carbon nanotubes on friction and wear of a piston ring and cylinder liner system under dry and lubricated conditions

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Friction 2017年第2期5卷 147-154页

作者： zhinan ZHANG Jun LIU Tonghai wu Youbai XIE State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong University Shanghai 200240 ChinaSchool of Mechanical Engineering Shanghai Jiao Tong University Shanghai 200240 China School of Mechanical Engineering Shanghai Jiao Tong University Shanghai 200240 China Key Laboratory of Education Ministry for Modern Design and Rotor-Bearing System Xi'an Jiaotong University Xi'an 710049 China

This study involves the application of carbon nanotubes (CNTs) to a piston ring and cylinder liner system in order to investigate their effect on friction and wear under dry and lubricated *** nanotubes were used as a solid lubricant and lubricant additive in dry and lubricated conditions,*** and measurement of friction and wear were conducted using a reciprocating *** analysis was performed using a scanning electron microscope and an energy dispersive *** results indicate that carbon nanotubes can considerably improve the tribological performance of a piston ring and cylinder liner system under dry sliding conditions,whereas improvement under lubricated conditions is not *** dry friction,the effective time of the CNTs is limited and the friction coefficient decreases with an increase in CNT ***,the dominant wear mechanism during dry friction is adhesive.

关键词： carbon nanotubes piston ring tribological behavior friction wear

Synthesized Multi-station Tribo-test System for Bio-tribological Evaluation in Vitro

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Chinese Journal of Mechanical Engineering 2016年第4期29卷 853-861页

作者： wu Tonghai DU Ying LI Yang WANG Shuo ZHANG zhinan Key Laboratory for Modern Design and Rotor-Bearing System of Ministry of Education Xi'an Jiaotong University State Key Laboratory of Mechanical Transmissions Chongqing University School of Mechanical Engineering Shanghai Jiao Tong University

Tribological tests play an important role on the evaluation of long-term bio-tribological performances of prosthetic materials for commercial *** tests focus on the motion simulation of a real joint in vitro with only normal loads and constant velocities,which are far from the real friction behavior of human joints characterized with variable loads and multiple *** order to accurately obtain the bio-tribological performances of artificial joint materials,a tribological tester with a miniature four-station tribological system is proposed with four distinctive ***,comparability and repeatability of a test are ensured by four equal stations of the ***,cross-linked scratch between tribo-pairs of human joints can be simulated by using a gear-rack meshing mechanism to produce composite *** this mechanism,the friction tracks can be designed by varying reciprocating and rotating ***,variable loading system is realized by using a ball-screw mechanism driven by a stepper motor,by which loads under different gaits during walking are ***,dynamic friction force and normal load can be measured *** verifications of the performances of the developed tester show that the variable frictional tracks can produce different wear debris compared with one-directional tracks,and the accuracy of loading and friction force is within ？5%.Thus the high consistency among different stations can be ***,the proposed tester system could provide more comprehensive and accurate bio-tribological evaluations for prosthetic materials.

关键词： artificial joint multi-station tribological tester bio-tribology testing system

Stability in terms of two measures for population growth models with impulsive perturbations

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International Journal of Biomathematics 2020年第6期13卷 199-211页

作者： zhinan Xia Qianlian wu Dingjiang Wang Department of Applied Mathematics Zhejiang University of Technology Hangzhou Zhejiang 310023P.R.China

In this paper,we establish some criteria for the stability of trivial solution of population growth models with impulsive *** working tools are based on the theory of generalized ordinary differential ***,the conditio... 详细信息

关键词： Population growth models impulsive perturbations generalized ordinary differential equations stability

运用临床思维提高早期肺癌的精确诊断—附17例首诊误诊原因病例分析

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当代医学 2019年第27期25卷 90-92页

作者：徐勇邹燎原徐根刘舒畅吴指南平江县第一人民医院放射科胸心学组湖南岳阳414500 平江县第一人民医院胸外科湖南岳阳414500 平江县第一人民医院呼吸内科湖南岳阳414500

目的探讨运用临床思维提高早期肺癌的精确诊断效果。方法选择2016年1月至2018年4月在本院进行诊治的肺小结节患者106例:所有患者首次检查都采用GE64排螺旋CT进行扫描,并应用临床思维进行分析。结果本次研究完成手术共69例,总检测成功率8... 详细信息

目的探讨运用临床思维提高早期肺癌的精确诊断效果。方法选择2016年1月至2018年4月在本院进行诊治的肺小结节患者106例:所有患者首次检查都采用GE64排螺旋CT进行扫描,并应用临床思维进行分析。结果本次研究完成手术共69例,总检测成功率89.86%(62/69),失败率10.14%(7/69),对比差异有统计学意义(χ^2=87.681,P=0.000)。结论运用临床思维包括通过综合评估以及规范随访等可提高早期肺癌的精确诊断效果,值得推广并广泛应用。

关键词：临床思维早期肺癌统一标准(薄层技术) 规范随访(3-3-6-12) 综合评估

Nanotribology of SiP nanosheets: Effect of thickness and sliding velocity

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Friction 2022年第12期10卷 2033-2044页

作者： Zishuai wu Tongtong YU Wei wu Jianxi LIU zhinan ZHANG Daoai WANG Weimin LIU Center of Advanced Lubrication and Seal Materials School of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi’an 710072China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China Qingdao Center of Resource Chemistry and New Materials Qingdao 266100China State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong UniversityShanghai 200240China

Two-dimensional compounds combining group IV A element and group V A element were determined to integrate the advantages of the two *** a typical 2D group IV–V material,SiP has been widely used in photodetection and photocatalysis due to its high carrier mobility,appropriate bandgap,high thermal stability,and low interlayer cleavage ***,its adhesion and friction properties have not been extensively ***,large-size and high-quality SiP crystals were obtained by using the flux *** nanosheets were prepared by using mechanical *** layer-dependent and velocity-dependent nanotribological properties of SiP nanosheets were systematically *** results indicate the friction force of SiP nanosheets decreases with the increase in layer number and reaches saturation after five *** coefficient of friction of multilayer SiP is *** mean friction force,frictional vibrations,and the friction strengthening effect can be affected by sliding ***,the mean friction force increases with the logarithm of sliding velocity at nm/s scale,which is dominated by atomic *** influence of frequency on frictional vibration is greater than speed due to the different influences on the change in contact *** friction strengthening saturation distance increases with the increase in speed for thick SiP *** results provide an approach for manipulating the nanofriction properties of SiP and serve as a theoretical basis for the application of SiP in solid lubrication and microelectromechanical systems.

关键词： SiP nanosheet 2D material atomic force microscopy(AFM) nanotribology

多囊卵巢综合征基因转录调控关联的生物信息分析

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江苏医药 2020年第4期46卷 365-369页

作者：占雷吴志南宋晓雪周安稳伯乐茅彩萍苏州大学附属第一医院生殖医学中心江苏215006

目的分析多囊卵巢综合征(PCOS)基因转录调控关联的生物信息。方法从整合基因表达汇编平台中共下载PCOS患者33例及健康对照30例的皮下脂肪组织样本转录组测序数据,比较两组基因表达数据,保留P<0.0005的1636个显著差异基因,进行GO数据库... 详细信息

目的分析多囊卵巢综合征(PCOS)基因转录调控关联的生物信息。方法从整合基因表达汇编平台中共下载PCOS患者33例及健康对照30例的皮下脂肪组织样本转录组测序数据,比较两组基因表达数据,保留P<0.0005的1636个显著差异基因,进行GO数据库的功能富集分析和KEGG数据库的生物信号通路富集分析。结果1636个显著差异基因富集在GO功能条目下,如在生物学过程集合中的嗜同性细胞黏附、肌丝滑动、肌肉收缩等,在细胞组分集合中的细胞质、肌原纤维节、核质等,在分子功能集合中的蛋白质结合、多聚腺嘌呤RNA结合及钙离子结合等(P<0.001)。1636个显著差异基因富集KEGG生物信号通路,如TNF信号通路、催产素信号通路、Ras信号通路、环磷酸腺苷信号通路、胰岛素信号通路及雌激素信号通路等(P<0.05)。结论PCOS表达基因的遗传学变化可能通过影响卵巢发育生物学过程及卵巢发育相关的信号通路的活性,从而促进PCOS的发生。

关键词：多囊卵巢综合征转录组测序功能富集生物信号通路