检索结果-南通市图书馆

排灌机械工程学报 2020年第2期38卷 157-162页

作者：袁志美周兰庭徐长华河海大学水利水电学院

从泵站工程事故成因出发,针对传统风险辨识方法及过程的不足,提出基于BIM的风险辨识方法.根据致险因素在BIM中辨识方法的不同将其分为静态与动态2种信息类型,设计提取并判断模型属性参数信息的流程,同时以三维可视化模型为基础,借助Visu... 详细信息

从泵站工程事故成因出发,针对传统风险辨识方法及过程的不足,提出基于BIM的风险辨识方法.根据致险因素在BIM中辨识方法的不同将其分为静态与动态2种信息类型,设计提取并判断模型属性参数信息的流程,同时以三维可视化模型为基础,借助Visual Studio2017开发平台,利用C#对Revit进行二次开发,实现三维模型特定属性参数提取.通过规范条文分析法构建安全知识库,将提取的BIM属性参数与安全知识库中标准安全知识进行比对分析,从而实现对安全知识库中静态致险因素的自动辨识及可视化输出,同时可以利用SQL语言查询相关致险因素及预防措施,利用Navisworks实现动态致险因素的辨识.以某泵站洞口及脚手架辨识为例,分析了这种方法的可行性,研究对优化施工安全规划,弥补安全管理人员安全风险知识的不足具有重要的参考意义.

关键词：泵站施工安全风险辨识 BIM 二次开发知识库

在线全文

学校读者我要写书评

暂无评论

水利工程投标中灰色多目标决策优选模型研究

人民黄河 2020年第4期42卷 120-123页

作者：周兰庭袁志美河海大学水利水电学院江苏南京210098

水利工程投标项目优选决策对承包商而言至关重要,关乎企业生存发展。为确保工程投标决策的合理性,综合考虑水利工程投标决策影响因素的不确定性、灰色关联性及信息不完备性,采用灰色关联分析法进行决策研究,同时为体现各评价指标对决策... 详细信息

水利工程投标项目优选决策对承包商而言至关重要,关乎企业生存发展。为确保工程投标决策的合理性,综合考虑水利工程投标决策影响因素的不确定性、灰色关联性及信息不完备性,采用灰色关联分析法进行决策研究,同时为体现各评价指标对决策结果的贡献度,采用无穷拟投项目多目标决策思想,以求解有限拟投项目多目标客观权重,构建灰色多目标决策优选模型。将该模型运用到某水利施工企业工程投标决策,证明该方法具有一定的实用性、易操作性及简捷性,可供类似工程投标决策借鉴。

关键词：水利工程投标决策灰色关联多目标决策

在线全文

学校读者我要写书评

暂无评论

基于云模型的区域河长制考核评价模型

水资源保护 2019年第1期35卷 41-46页

作者：唐新玥唐德善常文倩袁志美唐肖阳河海大学水利水电学院江苏南京210098

为考核区域河长制工作,从水资源保护、水域岸线管护、水污染防治、水环境治理与水生态修复、执法监督以及河长体系和工作机制建设情况6个方面选取25个评价指标,根据已划分的河长制考核评价等级与标准,构建了基于云模型的区域河长制考核... 详细信息

为考核区域河长制工作,从水资源保护、水域岸线管护、水污染防治、水环境治理与水生态修复、执法监督以及河长体系和工作机制建设情况6个方面选取25个评价指标,根据已划分的河长制考核评价等级与标准,构建了基于云模型的区域河长制考核评价模型;模型利用层次分析法与熵权法得出组合权重,运用X条件正向云发生器求得各指标隶属度,为避免最大隶属度原则造成的缺陷,通过加权平均法计算考核分值。采用该模型对南京市2013—2017年的河长制工作进行考核评价,得到的考核综合分值逐年提高,与南京市河长制实施情况基本一致,表明该模型适用于区域河长制考核评价。

关键词：河长制考核评价云模型南京市

假单胞菌单加氧酶基因的克隆表达及其在手性亚砜生物催化合成中的活性分析

在线全文

学校读者我要写书评

暂无评论

基因组学与应用生物学 2016年第4期35卷 886-891页

作者：袁志美李林艳邓成念郝丽颖仇治梅欧刚卫杨加伟遵义医学院生物化学教研室遵义563000

单加氧酶催化的硫醚底物不对称氧化反应是手性亚砜类药物绿色合成的新途径之一,而寻求高催化效率和高底物耐受性的硫醚单加氧酶仍是其难点和瓶颈。本研究从前期获得的能高效合成手性亚砜化合物的菌株中筛选和克隆了2个单加氧酶基因,构... 详细信息

单加氧酶催化的硫醚底物不对称氧化反应是手性亚砜类药物绿色合成的新途径之一,而寻求高催化效率和高底物耐受性的硫醚单加氧酶仍是其难点和瓶颈。本研究从前期获得的能高效合成手性亚砜化合物的菌株中筛选和克隆了2个单加氧酶基因,构建相应的表达载体并诱导表达重组蛋白,最后以苯甲硫醚为底物来初步探讨重组蛋白在生物催化合成苯甲亚砜中的活性。结果显示,成功构建了2个基因的表达载体并获得了大量的可溶性重组蛋白。而且,这2个重组蛋白均表现出了一定的生物催化活性,能将少量的苯甲硫醚底物转化为苯甲亚砜产物。本研究为将来进一步利用重组酶蛋白生物催化合成手性亚砜类化合物打下了一定的基础。

关键词：单加氧酶手性亚砜生物催化

基于CEEMDAN-PSR-KELM的大坝变形预测

在线全文

学校读者我要写书评

暂无评论

人民黄河 2019年第6期41卷 138-141,145页

作者：周兰庭徐长华袁志美卢韬河海大学水利水电学院

为提高大坝变形预测精度,针对大坝变形监测序列的非线性、非平稳性等特点,提出一种基于具有自适应噪声的完整集成经验模态分解(CEEMDAN)-相空间重构(PSR)-核极限学习机(KELM)的大坝变形预测模型。首先利用CEEMDAN算法将大坝变形监测序... 详细信息

为提高大坝变形预测精度,针对大坝变形监测序列的非线性、非平稳性等特点,提出一种基于具有自适应噪声的完整集成经验模态分解(CEEMDAN)-相空间重构(PSR)-核极限学习机(KELM)的大坝变形预测模型。首先利用CEEMDAN算法将大坝变形监测序列分解成为若干不同频率的子序列,然后对各序列进行相空间重构,依据重构的各个子序列分别建立相应的KELM预测模型,最后对各子序列预测结果进行叠加求和得到最终预测结果。通过实例对比分析表明,该模型在大坝变形预测中预测精度较高,对于大坝变形安全监测具有一定的实用价值。

关键词：大坝变形预测集成经验模态分解相空间重构核极限学习机

The dopaminergic system and Alzheimer's disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2495-2512页

作者： Yuhan Zhang yuan Liang Yixue Gu International Medical College Chongqing Medical UniversityChongqingChina College of Pharmacy Chongqing Medical UniversityChongqingChina Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of NeurologyChongqingChina

Alzheimer's disease is a common neurodegenerative disorder in older *** its prevalence,its pathogenesis remains unclea *** addition to the most widely accepted causes,which in clude excessive amyloid-beta aggregation,tau hyperphosphorylation,and deficiency of the neurotransmitter acetylcholine,numerous studies have shown that the dopaminergic system is also closely associated with the occurrence and development of this *** is a crucial catecholaminergic neurotransmitter in the human ***-associated treatments,such as drugs that target dopamine receptor D and dopamine analogs,can improve cognitive function and alleviate psychiatric symptoms as well as ameliorate other clinical *** r,therapeutics targeting the dopaminergic system are associated with various adverse reactions,such as addiction and exacerbation of cognitive *** review summarizes the role of the dopaminergic system in the pathology of Alzheimer's disease,focusing on currently available dopamine-based therapies for this disorder and the common side effects associated with dopamine-related *** aim of this review is to provide insights into the potential connections between the dopaminergic system and Alzheimer's disease,thus helping to clarify the mechanisms underlying the condition and exploring more effective therapeutic options.

关键词： adverse drug reaction Alzheimer's disease catecholamine dopamine receptor dopamine receptor heterodimers dopaminergic system neurodegenerative disease neurotransmitter signaling pathways traditional Chinese medicine treatment

Toward Analytical Homogenized Relaxation Modulus for Fibrous Composite Material with Reduced Order Homogenization Method

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2025年第1期82卷 193-222页

作者： Huilin Jia Shanqiao Huang Zifeng yuan HEDPS Center for Applied Physics and Technology(CAPT)Department of Mechanics and Engineering SciencePeking UniversityBeijing100871China State Key Laboratory for Turbulence and Complex Systems Peking UniversityBeijing100871China

In this manuscript,we propose an analytical equivalent linear viscoelastic constitutive model for fiber-reinforced composites,bypassing general computational *** method is based on the reduced-order homogenization(ROH)*** ROH method typically involves solving multiple finite element problems under periodic conditions to evaluate elastic strain and eigenstrain influence functions in an‘off-line’stage,which offers substantial cost savings compared to direct computational homogenization *** to the unique structure of the fibrous unit cell,“off-line”stage calculation can be eliminated by influence functions obtained *** the standard solid model to the ROH method enables the creation of a comprehensive analytical homogeneous viscoelastic constitutive *** method treats fibrous composite materials as homogeneous,anisotropic viscoelastic materials,significantly reducing computational time due to its analytical *** approach also enables precise determination of a homogenized anisotropic relaxation modulus and accurate capture of various viscoelastic responses under different loading *** sets of numerical examples,including unit cell tests,three-point beam bending tests,and torsion tests,are given to demonstrate the predictive performance of the homogenized viscoelastic ***,the model is validated against experimental measurements,confirming its accuracy and reliability.

关键词： Homogenized relaxation modulus viscoelastic standard solid model reduced order homogenization fibrous composite material

Optimal Scheduling of an Independent Electro-Hydrogen System with Hybrid Energy Storage Using a Multi-Objective Standardization Fusion Method

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Energy Engineering 2025年第1期122卷 63-84页

作者： SuliangMa ZeqingMeng Mingxuan Chen yuan Jiang School of Electrical and Control Engineering North China University of TechnologyBeijing100144China ChinaThree Gorges Technology Co. Ltd.Beijing100032China School of Automation and Electrical Engineering University of Science and Technology BeijingBeijing100083China

In the independent electro-hydrogen system(IEHS)with hybrid energy storage(HESS),achieving optimal scheduling is ***,it presents a challenge due to the significant deviations in values ofmultiple optimization objective functions caused by their physical *** deviations seriously affect the scheduling process.A novel standardization fusion method has been established to address this issue by analyzing the variation process of each objective function’s *** optimal scheduling results of IEHS with HESS indicate that the economy and overall energy loss can be improved 2–3 times under different optimization *** proposed method better balances all optimization objective functions and reduces the impact of their *** the cost of BESS decreases by approximately 30%,its participation deepens by about 1 ***,if the price of the electrolyzer is less than 15￥/kWh or if the cost of the fuel cell drops below 4￥/kWh,their participation will increase *** study aims to provide a more reasonable approach to solving multi-objective optimization problems.

关键词： Electro-hydrogen system multi-objective optimization standardization method hybrid energy storage system

Sex differences in aging and injured brain

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2901-2902页

作者： Jordan N.Williamson yuan Yang University of Illinois Urbana-Champaign Grainger College of EngineeringDepartment of BioengineeringUrbanaILUSA Carle Foundation Hospital Stephenson Family Clinical Research InstituteClinical Imaging Research CenterUrbanaILUSA University of Illinois Urbana-Champaign Beckman Institute for Advanced Science and TechnologyUrbanaILUSA Northwestern University Department of Physical Therapy and Human Movement SciencesChicagoILUSA

Background:The prevalence,age of onset,and symptomatology of traumatic brain injury,stroke,and neurodegenerative diseases(such as Alzheimer’s disease(AD),Parkinson’s disease,amyotrophic lateral sclerosis,and Huntington’s disease)differ substantially between males and *** higher prevalence of these brain disorders has been attributed to females having a greater longevity compared with *** one of the greatest risk factors of acquired brain injury(such as stroke,traumatic brain injury caused by fall)and neurodegenerative disease is age.

关键词： Huntington prevalence traumatic