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以黄疸为首发症状的艾滋病并卡波西肉瘤1例并文献复习

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安徽医药 2020年第2期24卷 256-258,I0002页

作者：吕茹胡志亮孙丙虎魏洪霞南京市第二医院感染病科

目的总结艾滋病并卡波西肉瘤以黄疸为首发者的的诊治经验。方法回顾性分析南京市第二医院感染病科2017年收治的1例以黄疸为首发症状的艾滋病并卡波西肉瘤病人的临床资料,并复习相关文献资料。结果病人黄疸1周入院,经抗感染、保肝降酶、... 详细信息

目的总结艾滋病并卡波西肉瘤以黄疸为首发者的的诊治经验。方法回顾性分析南京市第二医院感染病科2017年收治的1例以黄疸为首发症状的艾滋病并卡波西肉瘤病人的临床资料,并复习相关文献资料。结果病人黄疸1周入院,经抗感染、保肝降酶、退黄等对症治疗,黄疸仍迅速升高,且合并高热、咯血、呼吸衰竭,病情危重,皮肤紫蓝色结节活检提示卡波西肉瘤,经综合分析,考虑肿瘤累及肺、胆总管可能,予化疗后,黄疸降至正常,总体病情明显改善。结论卡波西肉瘤进展迅速,可累及多脏器,需及时病理诊断,黄疸可为其临床表现,治疗应以化疗为主。

关键词：获得性免疫缺陷综合征/并发症肉瘤,卡波西黄疸,阻塞性文献复习

HIV感染合并格林巴利综合征一例并文献复习

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东南大学学报（医学版） 2022年第5期41卷 713-716页

作者：吕茹胡志亮魏洪霞成骢南京市第二医院感染性疾病科江苏南京210000

目的:探讨人类免疫缺陷病毒(HIV)感染合并格林巴利综合征(GBS)的诊治经验。方法:回顾性分析南京市第二医院感染性疾病科2021年收治的1例HIV感染合并GBS患者的临床资料,并复习相关文献资料。结果:患者以GBS起病,查出HIV抗体阳性,病情进... 详细信息

目的:探讨人类免疫缺陷病毒(HIV)感染合并格林巴利综合征(GBS)的诊治经验。方法:回顾性分析南京市第二医院感染性疾病科2021年收治的1例HIV感染合并GBS患者的临床资料,并复习相关文献资料。结果:患者以GBS起病,查出HIV抗体阳性,病情进展迅速,危及生命,经我院多科室积极参与诊治,患者病情逐渐改善,顺利出院。结论:HIV感染可以诱导GBS发生,对于诊断为GBS的患者需注意筛查HIV抗体;反之,对于HIV感染者出现疼痛、对称性异常感觉和(或)肌肉无力等神经系统症状时需警惕GBS发生。HIV相关的GBS诊断与治疗可参考HIV阴性者,为保证患者得到及时有效的治疗,须注意多学科参与。

关键词：人类免疫缺陷病毒感染格林巴利综合征诊断治疗多学科文献复习

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儿童艾滋病并麻疹2例

安徽医药 2020年第7期24卷 1363-1365页

作者：吕茹胡志亮成骢魏洪霞南京市第二医院(南京中医药大学附属南京医院)感染病科江苏南京210003

目的总结儿童艾滋病并麻疹的临床及流行病学特征,期待未来能制定出针对此类人群的麻疹预防策略,以达到消除麻疹的目标。方法回顾性分析2例儿童艾滋病并麻疹的临床资料,并复习相关国内外文献资料。结果患艾滋病的儿童更容易感染麻疹,治... 详细信息

目的总结儿童艾滋病并麻疹的临床及流行病学特征,期待未来能制定出针对此类人群的麻疹预防策略,以达到消除麻疹的目标。方法回顾性分析2例儿童艾滋病并麻疹的临床资料,并复习相关国内外文献资料。结果患艾滋病的儿童更容易感染麻疹,治疗难度大,病死率高,现有的麻疹预防措施不足以应对此类特殊人群。结论对所有感染艾滋病的儿童进行额外的麻疹疫苗接种,尤其在抗逆转录病毒产生免疫重建后,至少再提供一次麻疹疫苗接种的机会。

关键词：获得性免疫缺陷综合征/并发症儿童麻疹接种文献复习

34例人类免疫缺陷病毒感染合并神经梅毒患者的临床特征、诊断及治疗分析

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实用心脑肺血管病杂志 2019年第12期27卷 98-101页

作者：徐春华池云陈伟胡志亮江苏省南京市第二医院

目的分析34例人类免疫缺陷病毒(HIV)感染合并神经梅毒(NS)患者的临床特征、诊断及治疗。方法选取2012-2018年在南京市第二医院感染科住院的HIV感染合并确诊及疑似NS患者34例,回顾性分析其一般资料(包括性别、年龄、感染途径、治疗史、HI... 详细信息

目的分析34例人类免疫缺陷病毒(HIV)感染合并神经梅毒(NS)患者的临床特征、诊断及治疗。方法选取2012-2018年在南京市第二医院感染科住院的HIV感染合并确诊及疑似NS患者34例,回顾性分析其一般资料(包括性别、年龄、感染途径、治疗史、HIV感染情况、症状),疾病分型及入院原因,血清学、脑脊液及影像学检查结果,治疗方法及预后。结果 (1)34例患者中男33例(占97.1%),女1例(占2.9%);平均年龄(39.4±11.6)岁;感染途径:同性冶游17例(占50.0%),异性冶游5例(占14.7%),同性冶游伴吸毒1例(占2.9%),其他11例(占32.4%);治疗史:驱梅治疗14例(占41.2%),高效抗逆转录病毒治疗(HAART)10例(占29.4%);HIV感染情况:CD4+细胞数目<350个/μl者23例(占67.6%),机会性感染12例(占35.3%);症状:有症状14例(占41.2%),无症状20例(占58.8%)。(2)14例有症状患者疾病分型:脑膜型8例(占23.5%),脑膜血管型2例(占5.9%),脑实质型4例(占11.8%);20例无症状患者入院原因:Ⅱ期梅毒4例(占11.8%),门诊苄星青霉素驱梅效果欠佳7例(占20.6%),初诊梅毒筛查NS 11例(占32.4%)。(3)血清学、脑脊液及影像学检查结果:血清快速血浆反应素环状卡片试验(RPR)滴度≥1:32者18例(占52.9%);34例患者脑脊液梅毒螺旋体明胶凝集试验(TPPA)均为阳性(占100.0%),脑脊液RPR阳性者13例(占38.2%),脑脊液白细胞计数升高者7例(占23.5%),脑脊液蛋白含量升高者19例(占55.9%);34例患者中行颅脑磁共振成像(MRI)检查者30例(占88.2%),颅脑CT检查者2例(占5.9%),其中颅脑MRI检查异常者13例(占43.3%)。(4)治疗方法:33例(占97.1%)患者采用水剂青霉素G联合苄星青霉素治疗,1例(占2.9%)患者因青霉素过敏而采用头孢曲松钠治疗。(5)预后:21例患者完成3个月~2年随访,其中17例(占81.0%)脑脊液RPR及TPPA转阴,9例(占42.9%)症状改善,1例(占4.8%)遗留神经系统损伤但血清学改善,2例(占9.5%)伴精神异常者症状有所改善。结论 HIV感染合并NS患者临床表现复杂,以无症状NS多见,需结合血清学、脑脊液及影像学检查进行综合判断,而NS的治疗仍首选青霉素。

关键词： HIV 神经梅毒脑脊液疾病特征诊断

Electrochemical conversion of methane to bridge the gap in the artificial carbon cycle

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Journal of Energy Chemistry 2025年第1期100卷 286-308页

作者： Yuhao Peng Yuefeng Song Ihar Razanau Juanxiu Xiao Wei Xiao Di hu Guoxiong Wang College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power Sources Wuhan University State Key Laboratory of Catalysis Dalian National Laboratory for Clean Energy iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Dalian Institute of Chemical Physics Chinese Academy of Sciences Laboratory of Physical-Chemical Technologies SSPA Scientific and Practical Materials Research Centre of NAS of Belarus State Key Laboratory of Marine Resources Utilization in South China Sea Collaborative Innovation Center of Marine Science and Technology School of Marine Science and Engineering Hainan University Department of Chemical and Environmental Engineering University of Nottingham Ningbo China

Methane, an abundant one-carbon（C1） resource, is extensively used in the industrial production of vital fuels and value-added chemicals. However, current industrial methane conversion technologies are energy-and carbon-intensive, mainly due to the high activation energy required to break the inert C–H bond, low selectivity, and problematic side reactions, including CO2emissions and coke deposition. Electrochemical conversion of methane（ECM） using intermittent renewable energy offers an attractive solution, due to its modular reactor design and operational flexibility across a broad spectrum of temperatures and pressures. This review emphasizes conversion pathways of methane in various reaction systems, highlighting the significance and advantages of ECM in facilitating a sustainable artificial carbon cycle. This work provides a comprehensive overview of conventional methane activation mechanisms and delineates the complete pathways of methane conversion in electrolysis contexts. Based on surface/interface chemistry, this work systematically analyzes proposed reaction pathways and corresponding strategies to enhance ECM efficiency towards various target products, including syngas, hydrocarbons, oxygenates, and advanced carbon materials. The discussion also encompasses opportunities and challenges for the ECM process, including insights into ECM pathways, rational electrocatalyst design, establishment of benchmarking protocols, electrolyte engineering, enhancement of CH4conversion rates, and minimization of CO2emission.

关键词： Methane Electrochemical conversion Reaction mechanism Catalyst design Electrode Electrocatalysis

A Novel Model for Describing Rail Weld Irregularities and Predicting Wheel-Rail Forces Using a Machine Learning Approach

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 555-577页

作者： Linlin Sun Zihui Wang Shukun Cui Ziquan Yan Weiping hu Qingchun Meng State Key Laboratory of High-Speed Railway Track System China Academy of Railway Sciences Corporation LimitedBeijing100081China Railway Engineering Research Institute China Academy of Railway Sciences Corporation LimitedBeijing100081China School of Aeronautic Science and Engineering Beihang UniversityBeijing100191China

Rail weld irregularities are one of the primary excitation sources for vehicle-track interaction dynamics in modern high-speed *** can cause significant wheel-rail dynamic interactions,leading to wheel-rail noise,component damage,and *** researchers have employed the vehicle-track interaction dynamic model to study the dynamic interactions between wheel and rail induced by rail weld geometry ***,the cosine wave model used to simulate rail weld irregularities mainly focuses on the maximum value and neglects the geometric *** this study,novel theoretical models were developed for three categories of rail weld irregularities,based on measurements of the high-speed railway from Beijing to *** vertical dynamic forces in the time and frequency domains were compared under different running *** forces generated by the rail weld irregularities that were measured and modeled,respectively,were compared to validate the accuracy of the proposed ***,based on the numerical study,the impact force due to rail weld irrregularity is modeled using an Artificial Neural Network(ANN),and the optimum combination of parameters for this model is *** results showed that the proposed model provided a more accurate wheel/rail dynamic evaluation caused by rail weld irregularities than that established in the *** ANN model used in this paper can effectively predict the impact force due to rail weld irrregularity while reducing the computation time.

关键词： Rail weld irregularity high-speed railway vehicle-track coupled dynamics wheel/rail dynamic vertical force artificial neural networks

Spin-glass behavior in the competing CoCrGaO_(4)cubic spinel system

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Nano Research 2025年第1期18卷 501-507页

作者： Jiyu hu Jiangli Ni Zhenfa Zi Chaocheng Liu School of Physics and Materials Engineering Hefei Normal UniversityHefei 230009China National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230026China

Spin glasses(SGs),generally defined as disordered systems with randomized competing interactions,are widely investigated complex *** the ground states of spin glasses is crucial for understanding the nature of disordered magnets and many other physical manifestations,while also helping to solve some hard combinatorial optimization problems across multiple ***,the intrinsic cause of SG has always been elusive,especially in spinel oxide ***,we report the SG behavior observed in the cubic spinel oxides CoCrGaO_(4),and provide a comprehensive understanding of its intrinsic *** results indicate a frustrated state under multi-magnetic competition,and the features of SG are confirmed by susceptibility *** fitting parameters ofτ0,T0,and zv of isothermal remanent magnetization further reveal the relaxation behavior and strong spin ***,the varying exchange coupling under different temperatures and magnetic fields is unveiled,which should be responsible for the disordered *** studies unravel the underlying mechanism responsible for doping-induced magnetic frustration and introduce CoCrGaO_(4)as a potential platform for investigating spin glass behavior,thereby advancing fundamental research on frustrated magnetism within the spinel system.

关键词： spin glass(SG) magnetic frustration magnetic competition spinel ferrites

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智能全自动电缆绝缘层切削装置的设计

今日自动化 2023年第11期 70-72页

作者：宋江红胡志亮朱伯涛李阳国网河北省电力有限公司邢台供电分公司河北邢台054001

传统的高压线剥线器在高压输电线与电闸和变压器连接时,高压线头的剥离过程中存在剥离精度低、工作效率低及施工人员安全性差的问题。针对这些问题,设计了一种智能全自动电缆绝缘层切削装置,适用于高压输电线现场接线的高智能、自动化... 详细信息

传统的高压线剥线器在高压输电线与电闸和变压器连接时,高压线头的剥离过程中存在剥离精度低、工作效率低及施工人员安全性差的问题。针对这些问题,设计了一种智能全自动电缆绝缘层切削装置,适用于高压输电线现场接线的高智能、自动化剥线器材,该设备能够实现高精度的剥离操作,提高施工效率,并减少施工人员因操作不当而引起的安全风险,同时提高接线的相关要求与技术指标。

关键词：智能全自动电缆绝缘层高压线剥线器

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一种改进的电缆主绝缘层剥离器研究与设计

今日自动化 2023年第12期 65-67页

作者：胡志亮宋江红朱伯涛李阳国网河北省电力有限公司邢台供电分公司河北邢台054001

目前电缆线路中,电缆切割以电工刀人工切削为主,精度差,易造成电缆对地绝缘降低、尖端放电甚至电缆头爆炸,严重制约电网安全运行。针对此问题,文章研究设计了一种适用广、工艺优、自动化程度高的多种电缆绝缘层切削工具,使用广适应卡套... 详细信息

目前电缆线路中,电缆切割以电工刀人工切削为主,精度差,易造成电缆对地绝缘降低、尖端放电甚至电缆头爆炸,严重制约电网安全运行。针对此问题,文章研究设计了一种适用广、工艺优、自动化程度高的多种电缆绝缘层切削工具,使用广适应卡套、连接套筒、减速器组成电动一体化装置,不仅适用多种截面电缆的主绝缘层,并且能精确加工不同倒角。该研究成果切削方法由断续切削转换为螺旋连续性切削,工艺精度提高7.3倍,作业效率提高4倍。该成果已在全国范围内实现规模化应用,截至目前推广应用了4985套。

关键词：电缆主绝缘层电缆主绝缘层剥离螺旋连续性切削精确加工倒角