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Association between Mental Health Literacy and Workplace Well-Being of Chinese Grassroots Civil Servants:The Chain Mediating Effects of Regulatory Emotional Self-Efficacy and Resilience

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International Journal of Mental Health Promotion 2024年第7期26卷 559-568页

作者： Yi Tang Yajun Zhao Zihan Jin Shengnan Wu zhijun Zhang Ju Zhou Ling Zhou Chongqing Academy of Governance Chongqing400041China School of Education and Psychology Southwest Minzu UniversityChengdu610041China School of Educational Sciences Chongqing Normal UniversityChongqing401331China Department of Psychology and Behavioral Sciences Zhejiang UniversityHangzhou310030China Nanping Experimental Primary School Chongqing400060China

This study aimed to investigate the relationship between mental health literacy(MHL)and workplace well-being(WWB)of Chinese grassroots civil servants,with regulatory emotional self-efﬁcacy(RESE)and resilience as mediating variables.A questionnaire survey was conducted among Chinese grassroots civil servants,with a valid sample size of 2673 after excluding missing values and conducting relevant data *** PROCESS was used to examine the relationship between MHL,RESE,resilience,and *** study found that MHL among grassroots civil servants was positively and signiﬁcantly correlated with WWB(r=0.73,p<0.01).RESE partially mediated the relationship between MHL and WWB(β=0.25,95%CI[0.22,0.28]).Resilience partially mediated the relationship between MHL and WWB(β=0.22,95%CI[0.19,0.26]).MHL had a positive effect on WWB through the chain mediating effect of RESE and resilience(β=0.05,95%CI[0.03,0.07]).There is a close relationship between MHL and WWB,where Chinese grassroots civil servants with higher levels of MHL can develop stronger RESE and resilience,leading to higher *** results of this study remind organizational institutions of Chinese grassroots civil servants that enhancing MHL,RESE,and resilience is an important pathway to promoting their WWB.

关键词： Mental health literacy workplace well-being regulatory emotional self-efﬁcacy resilience Chinese grassroots civil servants

Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury

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Neural Regeneration Research 2025年第5期20卷 1416-1430页

作者： Mou Gao Qin Dong Dan Zou zhijun Yang Lili Guo Ruxiang Xu Department of Neurosurgery Sichuan Academy of Medical Sciences and Sichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Department of Neurosurgery Chinese PLA General HospitalBeijingChina Department of Neurology Fu Xing HospitalCapital Medical UniversityBeijingChina

Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and *** previously reported that induced neural stem cells can modulate the behavior of activated microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological ***,the mechanism of CXCR4 upregulation in induced neural stem cells remains *** this study,we found that nuclear factor-κB activation induced by closed head injury mouse serum in microglia promoted CXCL12 and tumor necrosis factor-αexpression but suppressed insulin-like growth factor-1 ***,recombinant complement receptor 2-conjugated Crry(CR2-Crry)reduced the effects of closed head injury mouse serum-induced nuclear factor-κB activation in microglia and the levels of activated microglia,CXCL12,and tumor necrosis factor-α.Additionally,we observed that,in response to stimulation(including stimulation by CXCL12 secreted by activated microglia),CXCR4 and Crry levels can be upregulated in induced neural stem cells via the interplay among CXCL12/CXCR4,Crry,and Akt signaling to modulate microglial *** agreement with these in vitro experimental results,we found that Akt activation enhanced the immunoregulatory effects of induced neural stem cell grafts on microglial activation,leading to the promotion of neurological recovery via insulin-like growth factor-1 secretion and the neuroprotective effects of induced neural stem cell grafts through CXCR4 and Crry upregulation in the injured cortices of closed head injury ***,these beneficial effects of Akt activation in induced neural stem cells were positively correlated with the therapeutic effects of induced neural stem cells on neuronal injury,cerebral edema,and neurological disorders post–closed head *** conclusion,our findings reveal that Akt activation may enhance the immunoregulatory effects of induced neura

关键词： Akt signaling cerebral edema closed head injury Crry CXCR4 induced neural stem cell microglia neuroinflammation

Clay mineral transformation in medium–high maturity shale oil reservoir: a case study of the Qingshankou Formation， Songliao Basin， Northeast China

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Journal of Earth Science 2024年

作者： Xinping Liang Xueyu Yao Rukai Zhu Xiaojun Wang zhijun Jin Changrong Li Institute of Energy， Peking University State Key Laboratory of Shale Oil and Gas Enrichment Mechanisms and Effective Development College of Geosciences/National Key Laboratory of Petroleum Resources and Engineering， China University of Petroleum (Beijing) Research Institute of Petroleum exploration & Development PetroChina Petroleum Exploration and Production Research Institute SINOPEC

Currently， significant hurdles lie ahead in China’s lacustrine shale oil exploration and exploitation， particularly due to the high clay mineral content， which severely impacts pore development in organic-rich shales. In this study， we take the medium- to high-maturity shale of the Qingshankou Formation (K2qn) in the Gulong Sag， Songliao Basin， China， as an example and analyze the dynamic evolution of the clay minerals and their effects on pore development by core observations， scanning electron microscopy， X-ray diffraction， physical property and nitrogen adsorptions to provide a valuable reference for the effective evaluation of lacustrine clay-rich shale oil reservoirs. Our findings reveal that the dynamic transformation of clay minerals in the Qingshankou Formation is classified into three stages based on diagenesis， thermal maturity， and mineral characteristics: the initial stage (vitrinite reflectivity (Ro) 1.3%). Clay minerals play crucial roles in controlling shale reservoirs during the rapid transformation process， which is evidenced by the formation of shrinkage fractures， enhanced pore connectivity， increased porosity， and expanded space for shale oil adsorption and storage. In addition， authigenic quartz can form during the transformation of clay minerals， contributing to increased reservoir brittleness and improving the potential for reservoir fracturing.

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Neddylation is a novel therapeutic target for lupus by regulating double negative T cell homeostasis

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Signal Transduction and Targeted Therapy 2024年第2期9卷 738-750页

作者： Yun Zhang Lijun Du Chenxi Wang Zhangsheng Jiang Qingchi Duan Yiping Li zhijun Xie Zhixing He Yi Sun Lin Huang Liwei Lu Chengping Wen Key Laboratory of Chinese medicine rheumatology of Zhejiang Province Research Institute of Chinese Medical Clinical Foundation and ImmunologyCollege of Basic Medical ScienceZhejiang Chinese Medical UniversityHangzhou 310053China Department of General Surgery Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Cancer Institute(Key Laboratory of Cancer Prevention and Intervention China National Ministry of Education)of the Second Affiliated Hospital and Institute of Translational MedicineZhejiang University School of MedicineHangzhou 310029China Cancer Center of Zhejiang University Hangzhou 310029China Department of Pathology and Shenzhen Institute of Research and Innovation The University of Hong KongHong KongChina Chongqing International Institute for Immunology Chongqing 400038China

Systemic lupus erythematosus(SLE),a severe autoimmune disorder,is characterized by systemic inflammatory response,autoantibody accumulation and damage to *** dysregulation of double-negative(DN)T cells is considered as a crucial commander during ***,a significant type of protein post-translational modification(PTM),has been well-proved to regulate T cell-mediated immune ***,the function of neddylation in SLE is still ***,we reported that neddylation inactivation with MLN4924,a specific inhibitor of NEDD8-activating enzyme E1(NAE1),or genetic abrogation of Ube2m in T cells decreased DN T cell accumulation and attenuated murine lupus *** investigations revealed that inactivation of neddylation blocked Bim ubiquitination degradation and maintained Bim level in DN T cells,contributing to the apoptosis of the accumulated DN T cells in lupus *** double knockout(KO)lupus-prone mice(Ube2m-/-Bim-/-lpr)were generated and results showed that loss of Bim reduced Ube2m deficiency-induced apoptosis in DN T cells and reversed the alleviated lupus *** findings identified that neddylation inactivation promoted Bim-mediated DN T cell apoptosis and attenuated lupus ***,we also found that in SLE patients,the proportion of DN T cells was raised and their apoptosis was ***,compared to healthy groups,SLE patients exhibited decreased Bim levels and elevated Cullin1 neddylation ***,the inhibition of neddylation induced Bim-dependent apoptosis of DN T cells isolated from SLE ***,our findings provide the direct evidence about the function of neddylation during lupus,suggesting a promising therapeutic approach for this disease.

关键词： inactivation double finding

Engineering neuroregenerative microenvironment via aligned hydrogel-assisted magnetic stimulation for complete spinal cord injury repair

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Engineered Regeneration 2024年第2期5卷 139-152页

作者： Chun-Yi Yang Zhe Meng zhijun He Pengchao Ma Zhaohui Hou Kunkoo Kim Jingsong Lu Kaiyuan Yang Guihuai Wang Xiumei Wang State Key Laboratory of New Ceramics and Fine Processing Key Laboratory of Advanced Materials of Ministry of EducationSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Department of Neurosurgery Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing102218China

Utilizing biomaterials in tissue engineering has shown considerable promise for tissue regeneration,particularly through delivering multimodel cell-regulatory signals,including the material-related signals and extrinsic *** this research,we developed a magnetic-responsive aligned nanofiber fibrin hydrogel(MAFG),integrating the structured alignment of nanofibers and the pliability of fibrin hydrogel with an external magnetic *** design aimed to enhance the regenerative response in spinal cord injury treatment.A medium-strength magnetic field,aligned with the spinal cord,was applied to aid motor function recovery in rats with spinal cord *** use of MAFG in this context not only intensified the effect of the magnetic field but also encouraged the activation and differentiation of native neural stem ***,this method effectively steered macrophage polarization towards a beneficial M2 phenotype,addressing immune dysregulation at the injury *** parallel application of magnetic field stimulation through MAFG in a spinal cord injury model contributed to the concurrent promotion of neurogenesis,angiogenesis,and immunomodulation,resulting in marked improvement in motor function in *** investigation underscores the therapeutic potential of magnetic field stimulation and highlights how aligning this stimulation with the spinal cord can significantly enhance the regenerative milieu at the injury site.

关键词： Angiogenesis Neurogenesis Immunomodulation Magnetic-responsive hydrogel Magnetic stimulation

Chiral Pair Density Waves with Residual Fermi Arcs in RbV3Sb5

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Chinese Physics Letters 2024年第9期41卷 88-92页

作者： Xiao-Yu Yan Hanbin Deng Tianyu Yang Guowei Liu Wei Song Hu Miao zhijun Tu Hechang Lei Shuo Wang Ben-Chuan Lin Hailang Qin Jia-Xin Yin Department of Physics Southern University of Science and TechnologyShenzhen 518055China Materials Science and Technology Division Oak Ridge National LaboratoryOak RidgeTennessee 37831USA Beijing Key Laboratory of Optoelectronic Functional Materials MicroNano Devices Department of PhysicsRenmin University of ChinaBeijing 100872China Key Laboratory of Quantum State Construction and Manipulation(Ministry of Education) Renmin University of ChinaBeijing 100872China Shenzhen Institute for Quantum Science and Engineering Southern University of Science and TechnologyShenzhen 518055China Guangdong Provincial Key Laboratory of Quantum Science and Engineering Southern University of Science and TechnologyShenzhen 518055China Quantum Science Center of Guangdong-Hong Kong-Macao Greater Bay Area Shenzhen 518055China

The chiral 2×2 charge order has been reported and confirmed in the kagome superconductor RbV3Sb5,while its interplay with superconductivity remains elusive owing to its lowest superconducting transition temperature Tc of about 0.85K in the AV3Sb5 family(A=K,Rb,Cs)that severely challenges electronic spectroscopic ***,utilizing dilution-refrigerator-based scanning tunneling microscopy down to 30 mK,we observe chiral 2×2 pair density waves with residual Fermi arcs in *** find a superconducting gap of 150eV with substantial residual in-gap *** spatial distribution of this gap exhibits chiral 2×2 modulations,signaling a chiral pair density wave(PDW).Our quasi-particle interference imaging of the zero-energy residual states further reveals arc-like *** discuss the relation of the gap modulations with the residual Fermi arcs under the space-momentum correspondence between PDW and Bogoliubov Fermi states.

关键词： Fermi chiral utilizing

Dynamical behavior of memristor-coupled heterogeneous discrete neural networks with synaptic crosstalk

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Chinese Physics B 2024年第2期33卷 545-550页

作者：马铭磷熊康灵李志军贺少波 School of Automation and Electronic Information Xiangtan UniversityXiangtan 411105China

Synaptic crosstalk is a prevalent phenomenon among neuronal synapses,playing a crucial role in the transmission of neural ***,considering synaptic crosstalk behavior and investigating the dynamical behavior of discrete neural networks are highly *** this paper,we propose a heterogeneous discrete neural network(HDNN)consisting of a three-dimensional KTz discrete neuron and a Chialvo discrete *** two neurons are coupled mutually by two discrete memristors and the synaptic crosstalk is *** impact of crosstalk strength on the firing behavior of the HDNN is explored through bifurcation diagrams and Lyapunov *** is observed that the HDNN exhibits different coexisting attractors under varying crosstalk ***,the influence of different crosstalk strengths on the synchronized firing of the HDNN is investigated,revealing a gradual attainment of phase synchronization between the two discrete neurons as the crosstalk strength decreases.

关键词： discrete memristor synaptic crosstalk coexisting attractor phase synchronization

Antenna Design for Modern Mobile Phones: A Review

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Electromagnetic Science 2024年第2期2卷 55-90页

作者： Yan Wang Libin Sun Zhengwei Du zhijun Zhang Key Laboratory for Information Science of Electromagnetic Waves(MoE) School of Information Science and TechnologyFudan UniversityShanghai 200433China Shanghai Huawei Technologies Ltd.Shanghai 201206China Beijing National Research Center for Information Science and Technology Department of Electronic EngineeringTsinghua UniversityBeijing 100084China

Due to limited antenna space,high communication requirements,and strict regulatory constraints,the design of antennas for modern mobile phones has become an exceedingly challenging *** recent years,numerous studies have been conducted in this area,leading to significant *** review paper comprehensively summarizes recent progress made in antenna design for modern mobile ***,the challenges faced in antenna design for modern mobile phones are described,including bandwidth enhancement,integration and decoupling techniques,mm-wave array antennas,satellite communication antennas,as well as interactions between mobile antennas and the human ***,the basic antenna types(such as inverted-F,slot,loop,and planar inverted-F antennas)commonly used in modern metal-bezel mobile phones along with their key characteristics are briefly ***,the commonly exployed methods used in practical applications for designing wideband antennas within compact sizes and achieving decoupling among multiple antennas with wide bandwidths are ***,recent advances in the design of compact,wideband,and wide-angle scanning mm-wave arrays for modern mobile phones are ***,recent progress made in satellite communication antenna designs for modern mobile phones,including broadside and end-fire radiation patterns,is ***,recent studies on the interaction between mobile antennas and the human body are briefly ***,the future challenge of antenna design for mobile phones is briefly *** is our hope that this comprehensive review will provide readers with a systematic understanding of antenna design principles applicable to modern mobile phones.

关键词： Mobile antenna Bandwidth Decoupling mm-wave antenna Satellite communication antenna Specific absorption rate

Precise mode control of laser-written waveguides for broadband,low-dispersion 3D integrated optics

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Light(Science & Applications) 2024年第6期13卷 1186-1195页

作者： Yuying Wang Lijing Zhong Kuen Yao Lau Xuhu Han Yi Yang Jiacheng Hu Sergei Firstov Zhi Chen zhijun Ma Limin Tong Kin Seng Chiang Dezhi Tan Jianrong Qiu College of Optical Science and Engineering Zhejiang University310027HangzhouChina Institute of Light+X Science and Technology College of Information Science and EngineeringNingbo University315211NingboChina School of Optoelectronic Science and Engineering&Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University215006SuzhouChina Prokhorov General Physics Institute of the Russian Academy of Sciences Dianov Fiber Optics Research Center38 Vavilov str.Moscow119333Russia Zhejiang Lab 311121HangzhouChina College of Materials Science and Engineering Key Laboratory of Advanced Materials of Yunnan ProvinceKunming University of Science and Technology650093KunmingYunnanChina Department of Electrical Engineering City University of Hong Kong83 Tat Chee AvenueKowloonHong Kong SARChina School of Materials Science and Engineering Zhejiang University310027HangzhouChina

Three-dimensional(3D)glass chips are promising waveguide platforms for building hybrid 3D photonic circuits due to their 3D topological capabilities,large transparent windows,and low coupling *** present,the key challenge in scaling down a benchtop optical system to a glass chip is the lack of precise methods for controlling the mode field and optical coupling of 3D waveguide ***,we propose an overlap-controlled multi-scan(OCMS)method based on laser-direct lithography that allows customizing the refractive index profile of 3D waveguides with high spatial precision in a variety of *** the basis of this method,we achieve variable mode-field distribution,robust and broadband coupling,and thereby demonstrate dispersionless LP21-mode conversion of supercontinuum pulses with the largest deviation of<0.1 dB in coupling ratios on 210 nm *** approach provides a route to achieve ultra-broadband and low-dispersion coupling in 3D photonic circuits,with overwhelming advantages over conventional planar waveguide-optic platforms for on-chip transmission and manipulation of ultrashort laser pulses and broadband supercontinuum.

关键词： waveguide mode dispersion