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琼东南盆地深水区潜山油气成藏条件分析及有利目标预测——以陵南低凸起为例

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天然气地球科学 2024年第2期35卷 313-326页

作者：卫志杰甘军吴怡李金池何文涛王文博中海石油(中国)有限公司海南分公司海南海口570100

古潜山是南海西部琼东南盆地深水区重要的油气勘探领域,其中陵南低凸起古潜山领域天然气资源探明程度低,勘探潜力大。为加快陵南低凸起古潜山领域勘探进程,开展烃源条件、储盖组合、输导体系等油气成藏条件的综合评价,同时结合多种地球... 详细信息

古潜山是南海西部琼东南盆地深水区重要的油气勘探领域,其中陵南低凸起古潜山领域天然气资源探明程度低,勘探潜力大。为加快陵南低凸起古潜山领域勘探进程,开展烃源条件、储盖组合、输导体系等油气成藏条件的综合评价,同时结合多种地球物理手段预测潜山裂缝型储层,提出后续评价有利目标。结果表明:①陵南低凸起古潜山紧邻乐东—陵水富生烃凹陷,发育新生界厚层海相泥岩盖层与中生界花岗岩潜山储层优势储盖组合,具有大型沟源断裂、潜山内幕断裂、继承性构造脊等组成的复合运移模式以及源储压差大、近源充注的优势,成藏条件优越;②应用似然体、蚂蚁体、曲率体以及属性融合技术,结合区域构造应力场以及主要断层产状,综合预测陵南低凸起潜山裂缝型储层的展布特征,圈定有利勘探区带陵1构造、陵4构造,有助于推动后续勘探评价工作的进行。陵南低凸起古潜山整体油气成藏条件优越,预测多个构造储层发育,规模成藏概率大,是琼东南盆地继中央峡谷水道之外又一深水油气勘探新的有利方向。

关键词：陵南低凸起潜山琼东南盆地深水油气勘探油气成藏条件属性体属性融合裂缝型储层预测

低功耗检测CO_(2)的MEMS红外光源结构设计与仿真

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红外技术 2024年第8期46卷 858-863页

作者：滕雪松禹胜林魏志杰房村熊思娴王梦婷南京信息工程大学电子与信息工程学院江苏南京210000

传统的二氧化碳传感器存在着体积大、功耗高等问题,近年来随着半导体技术和材料的发展,MEMS技术逐渐成为传感器的研究重点。研究并设计了一种适用于二氧化碳传感器的微机电系统(micro-electro-mechanical system,MEMS)红外光源芯片结构... 详细信息

传统的二氧化碳传感器存在着体积大、功耗高等问题,近年来随着半导体技术和材料的发展,MEMS技术逐渐成为传感器的研究重点。研究并设计了一种适用于二氧化碳传感器的微机电系统(micro-electro-mechanical system,MEMS)红外光源芯片结构,采用硅(Si)作为基底,氧化硅(SiO_(2))-氮化硅(Si_(3)N_(4))-氧化硅(SiO_(2))作为红外光源的支撑层材料,辐射区的加热电阻采用延展性良好的铂(Pt),以铝(Al)为电极。光源的支撑层采用四轴大圆角悬空结构,极大减少了辐射区热量向衬底的热传导且稳定性较好,通过有限元仿真分析,该光源具有低功耗和结构稳固的特点。

关键词：微机械电子系统红外光源低功耗稳固结构

基于电磁混合耦合的SIW宽阻带带通滤波器设计

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通信技术 2024年第1期57卷 96-103页

作者：周为荣周鹤孟涛李帅合魏志杰中通服咨询设计研究院有限公司江苏南京210019 南京信息工程大学江苏南京210044

为实现阻带一段范围内依然具有良好的抑制能力,提出了电磁混合耦合的基片集成波导(Substrate Integrated Waveguide,SIW)宽阻带带通滤波器(Bandpass Filter,BPF)。根据模式的本征抑制和电磁混合耦合理论,合理地设置外部馈电端口、内部... 详细信息

为实现阻带一段范围内依然具有良好的抑制能力,提出了电磁混合耦合的基片集成波导(Substrate Integrated Waveguide,SIW)宽阻带带通滤波器(Bandpass Filter,BPF)。根据模式的本征抑制和电磁混合耦合理论,合理地设置外部馈电端口、内部耦合窗口及内部耦合圆孔阵列,抑制了频率低于TE_(105)和TE_(501)之前的所有高次模,并且使得工作模式TE101电耦合很好地传输。仿真与实测结果均显示,该滤波器的中心频率f_(0)=5.94 GHz,插入损耗为−3.46 dB,相对带宽为2.44%,当阻带宽度延伸至3.85 f0时,抑制深度优于20 dB。与经典的四阶SIW宽阻带带通滤波器相比,拥有相同的带宽时,该双层层叠的方式更加紧凑,有利于集成到微波电路系统中。

关键词：电磁混合耦合基片集成波导宽阻带带通滤波器

Apigenin is an anoikis sensitizer with strong anti-metastatic properties in experimental breast cancer

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Food Science and Human Wellness 2024年第4期13卷 2221-2233页

作者： Ruijie Xu zhijie Yao Hao Zhang Haitao Li wei Chen State Key Laboratory of Food Science and Technology Jiangnan UniversityWuxi 214122China School of Food Science and Technology Jiangnan UniversityWuxi 214122China

Loss of susceptibility to anoikis signals is a crucial step in *** resistance therefore represents a promising adjuvant therapeutic target for cancer *** this study,we have conducted a rationalized screening to search for novel leading anoikis sensitizer from daily *** 19 tested dietary phytochemicals,the best results were obtained with apigenin,a natural component of ***,apigenin sensitized breast cancer cells to anoikis,lowered the number of circulating tumor cells,and protected against breast cancer metastasis to lung in ***,we demonstrated that the thromboxane A_(2)(TXA_(2))-TXA_(2)receptor(TP)axis has a critical role in acquired anoikis resistance by activating PI3K-Akt signaling *** of TXA_(2)signaling up-regulated p53 as well as its target gene p21,caused a G1 phase arrest,and finally led to apoptosis in breast cancer ***_(2)level was positively correlated with breast cancer cell anoikis rate,and apigenin significantly inhibited TXA_(2)biosynthesis in vitro and in ***,we identified apigenin as a potent anoikis sensitizer with anti-metastatic properties in a mouse model of breast cancer,and these findings might provide a rationale for introducing apigenin supplementation to breast cancer patients.

关键词： Apigenin Anoikis Breast cancer metastasis Thromboxane A2

Realizing efficient emission and triple-mode photoluminescence switching in air-stable tin(IV)-based metal halides via antimony doping and rational structural modulation

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Aggregate 2024年第1期5卷 257-269页

作者： Xuefei He Hui Peng Qilin wei zhijie Zhou Guolun Zhang Zhentao Du Jialong Zhao Bingsuo Zou Department of Materials Physics and Chemistry State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite StructuresMOE Key Laboratory of New Processing Technology for Nonferrous Metals and Materialsand School of ResourcesEnvironment and MaterialsGuangxi UniversityNanningChina

Recently,many lead-free metal halides with diverse structures and highly efficient emission have been ***,their poor stability and single-mode emission color severely limit their ***,three homologous Sb^(3+)-doped zero-dimensional(0D)air-stable Sn(IV)-based metal halides with different crystal structures were developed by inserting a single organic ligand into SnCl_(4)lattice,which brings different optical *** photoexcitation,(C_(25)H_(22)P)SnC_(l5)@Sb⋅CH_(4O)(Sb^(3+)−1)does not emit light,(C_(25)H_(22)P)_(2)SnC_(l6)@Sb-α(Sb^(3+)−2α)shines bright yellow emission with a photoluminescence quantum yield(PLQY)of 92%,and(C_(25)H_(22)P)_(2)SnC_(l6)@Sb-β(Sb^(3+)−2β)exhibits intense red emission with a PLQY of 78%.The above three compounds show quite different optical properties should be due to their different crystal structures and the lattice ***,Sb^(3+)−1 can be successfully converted into Sb^(3+)−2αunder the treatment of C_(25)H_(22)PCl solution,accompanied by a transition from nonemission to efficient yellow emission,serving as a“turn-on”photoluminescence(PL)***,a reversible structure conversion between Sb^(3+)−2αand Sb^(3+)−2βwas witnessed after dichloromethane or volatilization treatment,accompanied by yellow and red emission ***,a triple-mode tunable PL switching of off-onI-onII can be constructed in Sb^(3+)-doped Sn(IV)-based ***,we demonstrated the as-synthesized compounds in fluorescent anticounterfeiting,information encryption,and optical logic gates.

关键词： information encryption Sb^(3+)-doping Sn(IV)-based metal halides structural modulation triple-mode

加强预处理方案异基因造血干细胞移植克服t(6;9)/DEK-NUP214急性髓系白血病患者不良预后

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临床血液学杂志 2024年第7期37卷 491-496页

作者：何海曹星玉赵艳丽熊敏卢岳张建平魏志杰刘德琰孙瑞娟河北燕达陆道培医院骨髓移植科河北廊坊065000 北京陆道培医院骨髓移植科

目的:探讨加强预处理方案异基因造血干细胞移植(allo-HSCT)治疗t(6;9)/DEK-NUP214急性髓系白血病(AML)的疗效。方法:对2015年3月—2023年4月应用加强预处理方案allo-HSCT治疗t(6;9)/DEK-NUP214 AML的32例患者资料进行回顾分析,观察疗效... 详细信息

目的:探讨加强预处理方案异基因造血干细胞移植(allo-HSCT)治疗t(6;9)/DEK-NUP214急性髓系白血病(AML)的疗效。方法:对2015年3月—2023年4月应用加强预处理方案allo-HSCT治疗t(6;9)/DEK-NUP214 AML的32例患者资料进行回顾分析,观察疗效。结果:32例患者均获得造血重建,白细胞和血小板植活中位天数分别为+13(10~20)d、+12(6~29)d。预处理相关毒性(RRT)多发生于预处理2周内,Ⅰ/Ⅱ级RRT发生率为59.4%(19/32),最常见的是胃肠道反应(13/32),其次为肝损伤(9/32)。32例患者均未发生Ⅲ/Ⅳ级RRT。移植后中位随访44(3~107)个月,3年总生存(OS)率90.3%、无复发生存(RFS)率86.2%、累计复发率3.1%、移植相关死亡率9.4%。移植时完全缓解患者20例与未缓解患者12例二组比较,其3年OS率和RFS率比较差异无统计学意义(OS率:95.0%vs 82.5%,P=0.28;RFS率:87.7%vs 82.5%,P=0.61)。20例患者发病时携带FLT3-ITD与12例非携带FLT3-ITD患者比较,3年OS率和RFS率比较差异无统计学意义(OS率:95.0%vs 82.5%,P=0.3;RFS率:87.7%vs 82.5%,P=0.63)。结论:加强预处理方案allo-HSCT可克服t(6;9)/DEK-NUP214 AML患者不良预后和具有良好的耐受性,生存不受移植前状态和携带FLT3-ITD影响。

关键词： DEK-NUP214 t(6 9) 急性髓系白血病预处理异基因造血干细胞移植

Electrocatalysis-driven sustainable plastic waste upcycling

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Electron 2024年第2期2卷 53-84页

作者： Gaihong Wang zhijie Chen wei wei Bing-Jie Ni Centre for Technology in Water and Wastewater School of Civil and Environmental EngineeringUniversity of Technology SydneySydneyNew South WalesAustralia UNSW Water Research Centre School of Civil and Environmental EngineeringThe University of New South WalesSydneyNew South WalesAustralia

With large quantities and natural resistance to degradation,plastic waste raises growing environmental concerns in the *** achieve the upcycling of plastic waste into value-added products,the electrocatalytic-driven process is emerging as an attractive option due to the mild opera-tionconditions,highreactionselectivity,***,this review provides a comprehensive overview of the upgrading of plastic waste via ***,key electrooxidation processes including the target products,intermediates and reaction pathways in the plastic electro-reforming process are ***,advanced electrochemical systems,including the integration of anodic plastic monomer oxidation and value-added cathodic reduction and photo-involved electrolysis processes,are *** design strategies of electrocatalysts with enhanced activity are highlighted and catalytic mechanisms in the electrocatalytic oxidation of plastic waste are *** promote the electrochemistry-driven sustainable upcycling of plastic waste,challenges and opportunities are further put forward.

关键词： catalyst design electrocatalytic reforming electrochemical oxidation hydrogen energy plastic waste

Adaptive Fourier Decomposition of the First Three SARS-CoV-2 Infection Waves with Epidemic Intervention—London,UK,2020-2022

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China CDC weekly 2024年第21期6卷 478-486,I0006-I0008页

作者： Zige Liu Guibin Lu Cheokieng Vong Zhiqi Zeng wei He zhijie Lin Cuiyun Lin Kaichin Hsieh Zifeng Yang Arlindo L.Oliveira Chitin Hon Department of Engineering Science Faculty of Innovation EngineeringMacao University of Science and TechnologyMacao SARChina Queen Ethelburga’s Collegiate Thorpe Underwood EstateYorkUK State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory HealthThe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina Respiratory Disease AI Laboratory on Epidemic and Medical Big Data Instrument Applications Department of Engineering ScienceFaculty of Innovation EngineeringMacao University of Science and TechnologyMacao SARChina Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases KingMed School of Laboratory MedicineGuangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina Faculty of Innovation Engineering School of Computer Science and EngineeringMacao University of Science and TechnologyMacao SARChina University College London UCL Faculty of Engineering SciencesLondonUK Guangzhou Laboratory Guangzhou CityGuangdong ProvinceChina Instituto de Engenharia de Sistemas e Computadores:Investigação e Desenvolvimento em Lisboa LisboaPortugal Instituto Superior Técnico Universidade de LisboaLisboaPortugal

Background:This study provides a detailed analysis of the daily fluctuations in coronavirus disease 2019(COVID-19)case numbers in London from January 31,2020 to February 24,*** primary objective was to enhance understanding of the interactions among government pandemic responses,viral mutations,and the subsequent changes in COVID-19 case ***:We employed the adaptive Fourier decomposition(AFD)method to analyze diurnal changes and further segmented the AFD into novel multi-component groups consisting of one to three *** restructured components were rigorously evaluated using Pearson correlation,and their effectiveness was compared with other signal analysis *** study introduced a novel approach to differentiate individual components across various time-frequency scales using basis decomposition ***:Analysis of London’s daily COVID-19 data using AFD revealed a strong correlation between the“stay at home”directive and high-frequency components during the first epidemic *** indicates the need for sustained implementation of vaccination policies to maintain their ***:The AFD component method provides a comprehensive analysis of the immediate and prolonged impact of governmental policies on the spread of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).This robust tool has proven invaluable for analyzing COVID-19 pandemic data,offering critical insights that guide the formulation of future preventive and public health strategies.

关键词： offering sustained London

The Impact of Medical Resources and Oral Antiviral Drugs on SARS-CoV-2 Mortality—Hong Kong SAR,China,2022

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China CDC weekly 2024年第21期6卷 469-477,I0001-I0005页

作者： Zhiqi Zeng Jingyi Liang zhijie Lin Wenda Guan wei He Qianying Li Lixi Liang weiqi Pan Zige Liu Guibin Lu Xiaoyan Deng Eric HY Lau Chitin Hon Zifeng Yang Guangzhou key laboratory for clinical rapid diagnosis and early warning of infectious diseases KingMed School of Laboratory MedicineGuangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina Macao Institute of Systems Engineering Macao University of Science and TechnologyMacao SARChina Respiratory Disease AI Laboratory on Epidemic Intelligence and Medical Big Data Instrument Applications Faculty of Innovative EngineeringMacao University of Science and TechnologyMacao SARChina State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory Healththe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou CityGuangdong ProvinceChina School of Public Health The University of Hong KongHong Kong SARChina Laboratory of Data Discovery for Health Hong Kong SARChina Guangzhou Laboratory Guangzhou CityGuangdong ProvinceChina

Introduction:The Omicron variant of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)demonstrates increased transmissibility compared to earlier strains,contributing to a significant number of fatalities in Hong Kong Special Administrative Region(HKSAR),*** medical resources and medications are essential in mitigating these *** study evaluates the effects of supplementary resources from the Chinese mainland during the fifth wave of the pandemic in ***:Vector autoregression(VAR)was employed to analyze data from the Oxford coronavirus disease 2019(COVID-19)Government Response Tracker to assess the effectiveness of control measures during five waves of the pandemic in ***,a transmission dynamics model was created to investigate the influence of supplementary medical resources from the Chinese mainland and oral medications on ***:In the initial four waves,workplace closures,restrictions on public events,international travel bans,and shielding the elderly significantly influenced pandemic ***,during the fifth wave,these measures showed no notable *** comparing a situation without extra medical resources or COVID-19 oral medication,there was a 17.7%decrease in COVID-19 fatalities with mainland medical resources and an additional 10.2%reduction with oral ***,they contributed to a 26.6%decline in ***:With the rapid spread of the virus,regional reallocation of medical resources may reduce mortality even when the local healthcare system is overstretched.

关键词： mainland Impact travel