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Journal of Cancer Therapy 2021年第1期12卷 1-9页

作者： zhihuan zhou Lan Bai Qinqin Zhao Department of Neurosurgery Sun Yat-sen University Cancer Center Guangzhou China

Objective: To explore the negative emotions of mothers during chemotherapy of their children with malignant brain tumors. Methods: The phenomenological method for qualitative studies was adopted;convenience sampling was used to conduct semi-structured interviews to the mothers of 9 children with malignant brain tumors who received chemotherapy from June 2019 to December 2019;the Colaizzi 7-step analytical method was implemented to collate and analyze the original data. Results: The results were summarized into six subjects: stressed, exhausted because of trying to control everything in home care, prone to excessive care, financially burdened, desperate for knowledge of patient care, and desperate for psychosocial support. Conclusions: Understanding the real experiences and inner feelings of mothers during chemotherapy of their children with malignant brain tumors is helpful for medical staff to learn about the psychological distress and needs of mothers of children with malignant brain tumors, so as to give them psychological support and even social support, and help the mothers and the families of children with malignant brain tumors get through a special period.

关键词： Children Brain Tumor Mother Negative Emotions Qualitative Study

Evaluation of the Effect of Chemotherapeutic Drug Training on Mobile Terminal for Neuro-Oncology Nurses Based on Kirkpatrick’s Model

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Neuroscience & Medicine 2020年第3期11卷 83-90页

作者： Lan Bai Qinqin Zhao zhihuan zhou Neurosurgery department Sun Yat-sen University Cancer Center Guangzhou China

Background: Since there has been training, there has been discussion about the effect of training. But training evaluation is not systematic until Kirkpatrick came up with the training evaluation model in 1959. At present, the prevailing model in the systematic summary of training evaluation is still The Kirkpatrick’s model. This model was further improved in 1994, more responsive to contemporary needs, and thus widely used all over the world. At the beginning, it was widely used in human resource management of enterprises. In recent years, this model has been gradually used in the medical field to evaluate the effect of medical training. The Kirkpatrick’s model has a systematic, integrated and persuasive evaluation system for trainees. It has good effects in the pre-service nurse training, the professional image and code of conduct nurses training, and the geriatric nurse training. At present, there are few studies on the chemotherapeutic drug training of neurologist nurses in China. In clinical work, nurses’ cognitive and practical behaviors of chemotherapeutic drug protection and drug extravasation prevention and treatment are insufficient. It directly harms the health of nursing staff and increases the complications of chemotherapy, increases pain of tumor patients, delays or interrupts chemotherapy, and aggravates the economic burden of patients. Especially, Chemotherapeutic drugs for neuro-oncology have particularity and necessity of urgent training. Objective: To investigate the effect of chemotherapeutic drug training through mobile terminal for neuro-oncology nurses based on the Kirkpatrick’s model. Methods: The training content and evaluation questionnaire for chemotherapeutic drugs were designed by nursing management personnel and senior nurses in our department according to the guidelines and common diseases requiring chemotherapy in th

关键词： Neuro-Oncology Mobile Terminal Kirkpatrick’s Model Training Chemotherapeutic Drugs

Analysis of Present Situation and Influencing Factors of Coping Methods by Parents of Children with Central Nervous System Tumors

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World Journal of Neuroscience 2020年第4期10卷 206-215页

作者： Lan Bai Qinqin Zhao Chunju Xiao zhihuan zhou Neurosurgery Department Sun Yat-sen University Cancer Center Guangzhou China

Background: Central nervous system (CNS) tumors are the most common solid tumors among children. Due to the severity of the tumors and the complexity of therapeutic regimes, it is very important to examine whether parents of the children with CNS tumors have positive coping methods against the disease. This study aims to analyze the coping methods of the parents and the factors influencing the methods. Methods: A total of 108 parents of brain cancer children admitted from January 2019 to September 2020 were selected as subjects. After collecting the general information of the parents, they were studied using the Coping Health Inventory for Parents (CHIP, Chinese version). Additionally, their coping pattern and the influencing factors were analyzed. Results: The average scores of the three subscales of the CHIP were (4.25 ± 0.939), (3.11 ± 1.205) and (3.60 ± 1.187), respectively. Univariate analysis showed that parents’ education, medical payment methods, places of residence and economic concerns were the main factors influencing the coping methods (all P Conclusions: Healthcare staff should fully evaluate the coping methods adopted by the parents having children with CNS tumors, take targeted nursing measures accordingly, and assist the parents in seeking social support and learning disease-related knowledge. In addition, public education on disease is equally important.

关键词： Coping Methods Parents Children Central Nervous System Tumors

Perioperative Nursing of a Case of Right Temporal Lobe Brain Abscess Ruptured into the Ventricle

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Journal of Cancer Therapy 2021年第5期12卷 233-239页

作者： Xiaoqun Chen Shuo Yang Qinqin Zhao zhihuan zhou Department of Neurosurgery Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou China

Objective: To explore the perioperative nursing method of brain abscess breaking into the ventricle. Methods: By reviewing the clinical data of 1 case of right temporal lobe brain abscess into the ventricle, the effective nursing methods were summarized. Results: The patient’s condition was advanced quickly, and the diagnosis was treated in time to avoid brain hernia, but the treatment was difficult because of the critical condition. Conclusion: Brain abscess is a very serious intracranial infectious disease. It is of great significance to observe the changes in patients’ condition and take effective nursing measures.

关键词： Brain Abscess Ventricle Perioperative Nursing

Application and Care of Two Kinds of Sphenoid Sinus Packing Materials after Pituitary Tumor Resection with the Transnasal Endoscopic Approach

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Neuroscience & Medicine 2020年第4期11卷 130-141页

作者： Shuo Yang Qiyu Feng Huidan Zhu zhihuan zhou Ji Zhang Department of Neurosurgery State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Sun Yat-sen University Cancer Center Guangzhou China

Background: Neuroendoscopic transsphenoidal approach for resection of pituitary adenomas has the advantages of less damage, fewer complications, and a faster recovery than the traditional approach and has beening favored by neurosurgeons. However, there has no standard method of selecting suitable packing materials after the operation to relieve pain in patients and achieve the ideal hemostatic effect. We compared the postoperative complications and treatment effects of two different packing materials in patients with pituitary adenomas. Objective: To investigate the advantages and disadvantages of using a catheter balloon and iodoform gauze for hemostasis in patients undergoing pituitary tumor resection by neuroendoscopic transsphenoidal approach. Materials and Methods: We retrospectively analyzed these data of 48 cases treated with pituitary adenoma resection by the single nasal approach from January 2018 to October 2019 in Sun Yat-sen University Cancer Center. According to the type of sphenoid sinus packing material used, these patients were divided into balloon tamponade oppression group (24 cases) and tela iodoformum oppression group (24 cases), respectively. The balloon tamponade oppression group received catheter balloon tamponade oppression hemostasis, and the tela iodoformum oppression group underwent tela iodoformum oppression hemostasis. The outcomes and complications were compared between the two groups in which two kinds of sphenoid sinus packing materials were used for hemostasis after tumor resection by transnasal endoscopic approach. For the catheter balloon compression hemostasis method, on account of the plasticity of the balloon, the volume of water in the balloon can be adjusted according to the size of the patient’s own sphenoid cavity. The amount of bleeding and several complications in terms of discomfort during placement and

关键词： Sphenoid Sinus Packing Material Pituitary Tumor Nursing

A Study on the Psychological Status of the Caregivers to Patients Out of ICU after Craniocerebral Tumor Surgery and Their Factors

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Neuroscience & Medicine 2021年第1期12卷 1-11页

作者： Ying Li Daili Zou Yu Yang Yunjia Li Qinqin Zhao zhihuan zhou Sun Yat-sen University Cancer Center Guangzhou China

Objective: So as to provide a theoretical basis for the future development of intervention measures to reduce the negative psychological mood of caregivers. To investigate the psychological status of the main caregivers for patients who were transferred out of ICU after craniocerebral tumor surgery and analyze their factors. Methods: 112 patients with cerebral tumor surgery were reviewed from sun yat-sen university cancer hospital. The research object is caregivers. The general data questionnaire, hospital anxiety depression scale and migration of ICU patients’ family members stress questionnaire scale investigation are collected. Multiple linear regression analysis in cerebral tumor patients with postoperative ICU transition out main factors influencing the psychological condition of the caregivers. Results: The anxiety and depression scores were (15.60 ± 5.83) and (38.73 ± 3.23) respectively. The results of multiple regression analysis showed that the gender, education level, relationship with the patient and family monthly income of the primary caregivers of the patients were the influencing factors of anxiety, depression and migration stress psychological state (P Conclusion: The main caregivers of patients who were transferred out of ICU after craniocerebral tumor surgery had relatively severe anxiety, depression and migration stress. Medical staff should pay attention to the psychological status of caregivers and take effective measures to promote their physical and mental health.

关键词： Craniocerebral Tumor Surgery ICU Transition Period Caregivers Psychological Status Factors Affecting

Individualized Sellar Floor Reconstruction Method and Nursing Strategy for the Intraoperative Cerebrospinal Fluid Leakage Caused by Neuroendoscopic Transsphenoidal Pituitary Adenoma Resection

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Open Journal of Nursing 2021年第5期11卷 367-377页

作者： Xiaoqun Chen Siting Fan Shuo Yang Jiayu Gu Qinqin Zhao zhihuan zhou Department of Neurosurgery Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou China Department of Gastric Surgery Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou China Department of Head and Neck Surgery Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou China

Objective: To explore the clinical effect of and the method and nursing strategy for sellar reconstruction for intraoperative cerebrospinal fluid (CSF) leakage in pituitary adenoma resection under neuroendoscopy. Methods: The data from 20 cases of intraoperative CSF leak caused by transsphenoidal pituitary adenoma resection were retrospectively analyzed. Six patients were treated with mucosal flap and artificial dural reconstruction of sellar (simple sellar floor reconstruction). In 45 patients, autologous fat, fascia lata, and artificial dura were used to repair and reconstruct the sellar floor (multilayer sellar floor reconstruction). After the operation, all patients underwent follow-up for 6 - 24 months. Results: Fifty patients were followed up without CSF leakage. One patient was cured after leakage of CSF through the lumbar cistern 1 month after discharge. Conclusion: For patients with CSF leakage during neuroendoscopic transsphenoidal pituitary adenoma resection, individualized sellar floor reconstruction should be adopted according to the degree of CSF leakage and the size of the sellar floor defect. Strict nursing measures can effectively prevent CSF leakage and reduce postoperative complications.

关键词： Pituitary Adenoma Neuroendoscopic Intraoperative Cerebrospinal Fluid Leakage Sellar Floor Reconstruction Nursing Strategy

痰瘀并治法对单纯性肥胖大鼠治疗作用的实验研究

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河北中医 2006年第3期28卷 221-223页

作者：周志焕天津中医学院 2003级博士研究生天津300193

目的探讨痰瘀并治法对单纯性肥胖大鼠的治疗效果及作用机制。方法给予高脂饲料制备单纯营养性肥胖大鼠模型,造模成功后分别以化痰方、活血方、痰瘀并治方及西药对照药治疗4周。观察小鼠治疗后体重及体重指数、瘦素、生长激素和胰岛素水... 详细信息

目的探讨痰瘀并治法对单纯性肥胖大鼠的治疗效果及作用机制。方法给予高脂饲料制备单纯营养性肥胖大鼠模型,造模成功后分别以化痰方、活血方、痰瘀并治方及西药对照药治疗4周。观察小鼠治疗后体重及体重指数、瘦素、生长激素和胰岛素水平。结果痰瘀并治可明显降低单纯性肥胖大鼠体重、体重指数、瘦素、胰岛素水平,升高生长激素水平。结论痰瘀并治法治疗单纯性肥胖较单纯化痰、活血法疗效好。

关键词：痰瘀并治单纯性肥胖实验研究

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中世纪全球史:法国与意大利学者的探索

全球史评论 2022年第1期 20-36,333页

作者：周之桓意大利比萨大学文明与知识形态学院

全球史是当下流行的史学趋势,法国和意大利的学者也从本国史学出发进行了探索。本文主要以《法兰西世界史》和《意大利世界史》为切入点,从法国与意大利比较的角度考察两国的中世纪全球史探索。法国中世纪史家的全球史研究影响了《意大... 详细信息

全球史是当下流行的史学趋势,法国和意大利的学者也从本国史学出发进行了探索。本文主要以《法兰西世界史》和《意大利世界史》为切入点,从法国与意大利比较的角度考察两国的中世纪全球史探索。法国中世纪史家的全球史研究影响了《意大利世界史》的书写,但《意大利世界史》的书写视角及其在意大利本国的接受情况却不同于法国。以公元800年查理曼加冕为例,法国与意大利历史学家以全球史视角对这一历史事件的不同解释和叙事,反映了法国与意大利两国学者不同的全球史路径及研究心态。

关键词：法国意大利《法兰西世界史》《意大利世界史》查理曼加冕

中枢神经系统肿瘤术后患者行6R程序哀伤辅导1例护理

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上海护理 2021年第6期21卷 63-65页

作者：周志欢李娜中山大学肿瘤防治中心广东广州510060

哀伤(bereavement)是指个人在失去所爱或所依恋的对象(主要指亲人)时面临的境况,包括悲伤与哀悼2种反应[1]。大部分人能相对顺利地接受亲人过世的事实,但少部分人表现出强烈而无法平复的哀伤反应,需要疏导丧亲的哀伤情绪[2]。约10%的丧... 详细信息

哀伤(bereavement)是指个人在失去所爱或所依恋的对象(主要指亲人)时面临的境况,包括悲伤与哀悼2种反应[1]。大部分人能相对顺利地接受亲人过世的事实,但少部分人表现出强烈而无法平复的哀伤反应,需要疏导丧亲的哀伤情绪[2]。约10%的丧亲者存在“延长哀伤障碍”,如果没有及时地进行干预和治疗,将会给其带来持久的伤害[3]。

关键词：肿瘤中枢神经系统哀伤辅导 6R程序模式个案