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Nano Research 2022年第8期15卷 7614-7621页

作者： Rui Wang Xin Tong zhihang long Ali Imran Channa Hongyang Zhao Xin Li Mengke Cai Yimin You Xuping Sun Zhiming Wang Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China Yangtze Delta Region Institute(Huzhou) University of Electronic Science and Technology of ChinaHuzhou 313001China Institute for Advanced Study Chengdu UniversityChengdu 610106China Department of Materials Science and Engineering Hongik UniversitySeoul 04066Republic of Korea

Colloidal core/shell quantum dots(QDs)with environment-friendly feature and controllable optoelectronic properties are promising building blocks in emerging solar *** this work,we rationally design and tailor the eco-friendly CuInSe(CISe)/ZnSe core/shell QDs by Mn doping and stoichiometric optimization(i.e.,molar ratios of Cu/In).It is demonstrated that Mn doping in In-rich CISe/ZnSe core/shell QDs can effectively engineer the charge kinetics inside the QDs,enabling efficient photogenerated electrons transfer into the shell for retarded charge *** a result,a solar-driven photoelectrochemical(PEC)device fabricated using the optimized Mn-doped In-rich CISe/ZnSe core/shell QDs(Cu/In ratio of 1/2)exhibits improved charge extraction and injection,showing a~3.5-fold higher photocurrent density than that of the pristine CISe/ZnSe core/shell QDs under 1 sun AM 1.5G *** findings indicate that transition metal doping in“green”nonstoichiometric core/shell QDs may offer a new strategy for achieving high-efficiency solar energy conversion applications.

关键词： eco-friendly colloidal quantum dot transition metal doping optoelectronic engineering photoelectrochemical cell

大兴安岭地区重点保护和珍稀动物保护空缺分析

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生物多样性 2022年第2期30卷 37-46页

作者：李海萍徐竹青龙志航中国人民大学环境学院北京100872

大兴安岭地区是我国唯一的寒温带针叶林生态区,具有全球重要性和特殊的自然保护价值。本研究针对该地区重点保护及珍稀动物未全部纳入保护地范围以及保护地分布破碎化的现状,在建立物种信息数据库的基础上,生成该地区重点保护及珍稀动物... 详细信息

大兴安岭地区是我国唯一的寒温带针叶林生态区,具有全球重要性和特殊的自然保护价值。本研究针对该地区重点保护及珍稀动物未全部纳入保护地范围以及保护地分布破碎化的现状,在建立物种信息数据库的基础上,生成该地区重点保护及珍稀动物10 km×10 km物种空间分布数据,并结合土地利用、植被覆盖、海拔和坡度等与栖息地相关的辅助数据,分析重点保护及珍稀动物的现有空间分布格局,以Shannon-Wiener多样性指数作为重点保护和珍稀动物的丰富度指标,通过将现有保护地范围与物种空间分布进行叠加,得到重点保护及珍稀动物的保护空缺。结果显示:(1)现有空缺区域内濒危、易危和近危物种均有分布,主要保护空缺对象有黑嘴松鸡(Tetrao parvirostris)、紫貂(Martes zibellina)、小天鹅(Cygnus columbianus)等;(2)保护程度较高的区域主要位于额尔古纳市北部和呼玛县西部等地。尽管重点保护和珍稀动物的空间分布与现有保护地范围基本匹配,但不同地理空间仍存在不同程度的保护空缺;(3)保护空缺主要有两种类型,即尚未受到保护的空白地区和未被完全纳入现有保护地的空缺地。基于以上结果,建议针对两类不同的保护空缺采取不同的保护措施,如对于根河市与牙克石市交界处未建立保护地的保护空白区,建议新建保护区或保护小区;对于重点保护和珍稀动物未被完全纳入现有保护地体系的区域,如内蒙古阿尔山自然保护区北部外延的空缺地,建议通过对现有保护地进行相应程度的扩建,完善现有保护地体系,从而促进大兴安岭地区重点保护及珍稀动物的保护进程。

关键词：大兴安岭地区重点保护动物物种多样性自然保护区空缺分析

The complex effects of miR-146a in the pathogenesis of Alzheimer's disease

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Neural Regeneration Research 2025年第5期20卷 1309-1323页

作者： Yunfan long Jiajia Liu Yu Wang Haidong Guo Guohong Cui Department of Neurology Shanghai No.9 People’s HospitalShanghai Jiaotong University School of MedicineShanghaiChina Academy of Integrative Medicine Shanghai University of Traditional Chinese MedicineShanghaiChina School of Integrative Medicine Shanghai University of Traditional Chinese MedicineShanghaiChina Department of Neurology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChina

Alzheimer's disease is a neurodegenerative disorder characterized by cognitive dysfunction and behavioral *** plaques formed through the extracellular deposition of amyloid-βproteins,as well as neurofibrillary tangles formed by the intracellular deposition of hyperphosphorylated tau proteins,comprise two typical pathological features of Alzheimer's *** symptomatic treatment,there are no effective therapies for delaying Alzheimer's disease ***(miR)are small,non-coding RNAs that negatively regulate gene expression at the transcriptional and translational levels and play important roles in multiple physiological and pathological ***,miR-146a,a NF-κB-regulated gene,has been extensively implicated in the development of Alzheimer's disease through several *** has demonstrated substantial dysregulation of miR-146a both during the initial phases and throughout the progression of this *** R-146a is believed to reduce amyloid-βdeposition and tau protein hyperphosphorylation through the TLR/IRAK1/TRAF6 pathway;however,there is also evidence supporting that it can promote these processes through many other pathways,thus exacerbating the pathological manifestations of Alzheimer's *** has been widely reported that miR-146a mediates synaptic dysfunction,mitochondrial dysfunction,and neuronal death by targeting m RNAs encoding synapticrelated proteins,mitochondrial-related proteins,and membrane proteins,as well as other *** the impact on glial cells,miR-146a also exhibits differential *** one hand,it causes widespread and sustained inflammation through certain pathways,while on the other hand,it can reverse the polarization of astrocytes and microglia,alleviate neuroinflammation,and promote oligodendrocyte progenitor cell differentiation,thus maintaining the normal function of the myelin sheath and exerting a protective effect on *** this review,we provide a

关键词： Alzheimer's disease amyloid-β glial cells microRNAs miR-146a neuroinflammatory

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全球CCUS技术专利布局与发展态势分析

科技通报 2024年第7期40卷 107-113页

作者：王大伟孟雨隗筱琦龙志航中国科学技术信息研究所北京100038 国网信息通信产业集团有限公司信通研究院北京100052

本文对碳捕集利用与封存(carbon capture,utilization and storage,CCUS)专利进行多粒度研究,揭示其发展概况与关键技术发展态势,为CCUS发展部署提供决策支撑。首先,运用专利计量法从时间、地域等方面进行粗粒度分析,解析CCUS发展趋势... 详细信息

本文对碳捕集利用与封存(carbon capture,utilization and storage,CCUS)专利进行多粒度研究,揭示其发展概况与关键技术发展态势,为CCUS发展部署提供决策支撑。首先,运用专利计量法从时间、地域等方面进行粗粒度分析,解析CCUS发展趋势、技术流动,挖掘技术热点和典型机构。其次,提出关键词抽取与分级合作关系网挖掘方法,获取共词网络与发明人分级合作关系网络。最后,利用Neo4j、Gephi实现CCUS关键技术的细粒度分析与可视化展示。以Innography收录的CCUS专利文献作为数据源,分析发现CCUS技术正处于交错发展期,中美是CCUS技术的领跑者;气体或蒸汽的分离等是CCUS最关键的前沿性技术;CCUS技术的研究机构及发明人呈现出聚集的发展态势。根据分析结果,为CCUS技术发展的战略布局提出建议。

关键词： CCUS技术专利计量 Gephi复杂网络分析共现网络

Recent advances of metal vacancies in energy and environmental catalysis:Synthesis,characterization,and roles

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Green Energy & Environment 2025年第1期10卷 84-108页

作者： long Sun Shunzheng Zhao Sirui Gao Ronghui Zhu Yiran Tan Xiaolong Tang Honghong Yi School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing100083China Beijing Key Laboratory of Resource-oriented Treatment of Industrial Pollutants Beijing100083China

With the ongoing depletion of fossil fuels,energy and environmental issues have become increasingly critical,necessitating the search for effective ***,being one of the hallmarks of modern industry,offers a promising avenue for ***,the question of how to significantly enhance the performance of catalysts has gradually drawn the attention of *** engineering,a commonly employed and effective approach to improve catalyst activity,has become a significant research focus in the catalysis field in recent *** vacancies have received extensive attention due to their simple ***,exploration of metal vacancies has remained stagnant for a considerable period,resulting in a scarcity of comprehensive reviews on this ***,based on the latest research findings,this paper summarizes and consolidates the construction strategies for metal vacancies,characterization techniques,and their roles in typical energy and environmental catalytic ***,it outlines potential challenges in the future,aiming to provide valuable references for researchers interested in investigating metal vacancies.

关键词： Metal vacancies Catalysis Construction strategies Characterization techniques Roles

Tangled but ordered human mitochondrial tRNA maturation

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Science China Life Sciences 2025年

作者： Shi-Ying Yao Xiao-long Zhou Key Laboratory of RNA Innovation Science and Engineering CAS Center for Excellence in Molecular Cell Science Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of Sciences University of Chinese Academy of Sciences Key Laboratory of Systems Health Science of Zhejiang Province School of Life Science Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences

Mitochondria are cellular organelles that originate from an endosymbiotic bacterial ancestor and are primarily responsible for ATP generation via oxidative phosphorylation (OXPHOS). OXPHOS is conducted by five mitochondrial respiratory complexes in the inner mitochondrial membrane. Human mitochondria possess a distinct genome, a small, circular, doublestranded DNA (mtDNA) of 16,569 base pairs.

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Research on the balance optimization algorithm of image recognition accuracy and speed based on autocollimator measurement

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Optoelectronics Letters 2025年第2期21卷 121-128页

作者： LI Renpu MA long CUI Jiwen GUO Junqi Andrei KULIKOV WEN Dandan Chongqing Engineering Research Center of Intelligent Sensing Technology and Microsystem Chongqing University of Post and Telecommunications School of Instrumentation Science and Engineering Harbin Institute of Technology Higher School of Engineering and Technology ITMO University

The autocollimator is an important device for achieving precise,small-angle,non-contact *** primarily obtains angular parameters of a plane target mirror indirectly by detecting the position of the imaging *** is limited report on the core algorithmic techniques in current commercial products and recent scientific *** paper addresses the performance requirements of coordinate reading accuracy and operational speed in autocollimator image *** proposes a cross-image center recognition scheme based on the Hough transform and another based on Zernike moments and the least squares *** experimental evaluation of the accuracy and speed of both schemes,the optimal image recognition scheme balancing measurement accuracy and speed for the autocollimator is *** these,the center recognition method based on Zernike moments and the least squares method offers higher measurement accuracy and stability,while the Hough transform-based method provides faster measurement speed.

关键词： Least squares approximations

Sporadic E responds to the 2022 Tonga volcano eruptions recorded by the Meridian Project

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Earth and Planetary Physics 2025年第1期9卷 20-28页

作者： YangYi Sun Tao Yu Jin Wang Chi long School of Geophysics and Geomatics China University of Geosciences(Wuhan)Wuhan 430047China School of Physics and Electronic Science Guizhou Normal UniversityGuizhou 550001China

In this study,ionosonde observations over Fuke(19.5°N,109.1°E),Wuhan(30.5°N,114.4°E),and Mohe(53.5°N,122.3°E)were analyzed to demonstrate the responses of the sporadic E()to the severe atmospheric disturbances caused by the Tonga volcanic eruptions on January 15,*** most prominent signature was the disappearance of the layer after~10:00 UT over Wuhan and Fuke,which was attributed to the vertical drift caused by the *** occurred intermittently after 13:00 UT following the arrival of the tropospheric Lamb *** examine the causal mechanism for the intermittence,we also included data of horizontal winds in the mesosphere and lower thermosphere region recorded by the meteor radars at Wuhan and Mohe in this *** wind disturbances with periods of~20 hours contributed to the formation of the layer in the nighttime on January 15.

关键词： sporadic E Tonga eruptions neutral wind disturbances

Enhanced autophagic clearance of amyloid-βvia histone deacetylase 6-mediated V-ATPase assembly and lysosomal acidification protects against Alzheimer's disease in vitro and in vivo

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Neural Regeneration Research 2025年第9期20卷 2633-2644页

作者： Zhimin long Chuanhua Ge Yueyang Zhao Yuanjie Liu Qinghua Zeng Qing Tang Zhifang Dong Guiqiong He Institute of Neuroscience School of Basic Medical SciencesChongqing Medical UniversityChongqingChina Department of Anatomy Chongqing Medical UniversityChongqingChina Department of Physiology Chongqing Medical UniversityChongqingChina Pediatric Research Institute Children’s Hospital of Chongqing Medical UniversityChongqingChina Ministry of Education Key Laboratory of Child Development and Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina National Clinical Research Center for Child Health and Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina

Recent studies have suggested that abnormal acidification of lysosomes induces autophagic accumulation of amyloid-βin neurons,which is a key step in senile plaque ***,resto ring normal lysosomal function and rebalancing lysosomal acidification in neurons in the brain may be a new treatment strategy for Alzheimer's *** acetylation/deacetylation plays a central role in lysosomal ***,we show that inhibiting the classic microtubule deacetylase histone deacetylase 6 with an histone deacetylase 6 shRNA or thehistone deacetylase 6 inhibitor valproic acid promoted lysosomal reacidification by modulating V-ATPase assembly in Alzheimer's *** rthermore,we found that treatment with valproic acid markedly enhanced *** clearance of amyloid-βaggregates,and ameliorated cognitive deficits in a mouse model of Alzheimer's *** findings demonstrate a previously unknown neuroprotective mechanism in Alzheimer's disease,in which histone deacetylase 6 inhibition by valproic acid increases V-ATPase assembly and lysosomal acidification.

关键词： Alzheimer's disease amyloid-β APP/PS1 mice autophagy cognitive impairment histone deacetylase 6 lysosomal acidification microtubule acetylation valproic acid V-ATPase

An Unprecedented Efficiency with Approaching 21%Enabled by Additive‑Assisted Layer‑by‑Layer Processing in Organic Solar Cells

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Nano-Micro Letters 2025年第2期17卷 372-375页

作者： Shuai Xu Youdi Zhang Yanna Sun Pei Cheng Zhaoyang Yao Ning Li long Ye Lijian Zuo Ke Gao Key Laboratory of Advanced Green Functional Materials College of ChemistryChangchun Normal UniversityChangchun 130032People’s Republic of China Shandong Provincial Key Laboratory for Science of Material Creation and Energy Conversion School of Chemistry and Chemical EngineeringShandong UniversityQingdao 266237People’s Republic of China College of Polymer Science and Engineering Sichuan UniversityChengdu 610065People’s Republic of China State Key Laboratory and Institute of Elemento‑Organic Chemistry Centre of Nanoscale Science and Technology and Key Laboratory of Functional Polymer MaterialsRenewable Energy Conversion and Storage Center(RECAST)College of ChemistryNankai UniversityTianjin 300071People’s Republic of China Institute of Polymer Optoelectronic Materials and Devices State Key Laboratory of Luminescent Materials and Devices South China University of TechnologyGuangzhou 510640People’s Republic of China Tianjin Key Laboratory of Molecular Optoelectronic Sciences School of Materials Science and EngineeringTianjin UniversityTianjin 300350People’s Republic of China State Key Laboratory of Silicon Materials MOE Key Laboratory of Macromolecular Synthesis and FunctionalizationDepartment of Polymer Science and EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China

Recently published in Joule,Feng Liu and colleagues from Shanghai Jiaotong University reported a record-breaking 20.8%power conversion efficiency in organic solar cells(OSCs)with an interpenetrating fibril network active layer morphology,featuring a bulk p-in structure and proper vertical segregation achieved through additive-assisted layer-by-layer *** optimized hierarchical gradient fibrillar morphology and optical management synergistically facilitates exciton diffusion,reduces recombination losses,and enhances light capture *** approach not only offers a solution to achieving high-efficiency devices but also demonstrates the potential for commercial applications of OSCs.

关键词： Organic solar cells Additive-assisted layer-by-layer processing Three-dimensional fibril morphology Bulk p-i-n structure Optical management