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Individualized coefficient of variability cut-off values for reducing the risk of hypoglycemia in Chinese type 1 diabetes mellitus(T1DM)patients

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Chinese Medical Journal 2024年第2期137卷 244-246页

作者： Jiaqi Li Keyu guo Liyin Zhang Jianan Ye Xia Li zhiguang Zhou Lin Yang National Clinical Research Center for Metabolic Diseases Key Laboratory of Diabetes Immunology(Central South University)Ministry of Educationand Department of Metabolism and EndocrinologyThe Second Xiangya Hospital of Central South UniversityChangshaHunan 410011China

To the Editor:Type 1 diabetes mellitus(T1DM)is a progressive disease caused by severe islet b-cell function impairment,resulting in high glucose variability(GV)in patients.[1]While intensive insulin treatment enabled T1DM patients to achieve near-normal glucose,reflected by reduced hemoglobin A1c(HbA1c)levels,stricter HbA1c targets were associated with an increased risk of hypoglycemia,which would compromise patients’quality of life and survival.[2]Recent studies suggest that GV reflects hypoglycemia better than HbA1c alone,and continuous glucose monitoring(CGM)provides a more comprehensive glycemic profile for better glucose indices assessment.[3]Therefore,we aimed to explore the relationship between the coefficient of variability(CV)of blood glucose and hypoglycemia in T1DM patients with different HbA1c levels and to identify the optimal cut-off values of CV for reducing the hypoglycemia risk in Chinese T1DM patients.

关键词： T1DM patients mellitus

One Step and In Situ Synthesis of Edible Lubricant-infused Surface Using All-in-one Solution

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Journal of Bionic Engineering 2023年第5期20卷 1879-1890页

作者： Daheng Wang Jinxia Huang zhiguang guo State Key Laboratory of Refractories and Metallurgy Wuhan University of Science&TechnologyWuhan430081China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou730000China Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials Hubei UniversityWuhanChina

Edible Lubricant-Infused Surface(ELIS)was fabricated through antisolvent method by adding ethyl oleate(lubricant/antisolvent),ethanol(solvent)and shellac(solute/base layer of ELIS)into an all-in-one solution to in-situ prepare ELIS through single step of solvent evaporation.The ELIS comprising sub-micro-to micro-scaled shellac particles shows water and food liquid slippery,transparency,stability against abrasion and lubricant retaining ability against sheer force.Using all edible material to fabricated ELIS is a more efficient route for application when compared with other Lubricant-Infused Surface(LIS).Traditional fabrication for LIS included steps such as:base layer fabrication,lubricant infusion,excess lubricant removal,UV light treatment and chemical etching.The method proposed in this article could further simplify the preparation to an all-in-one solution and simplify the synthesis process to only 60-degree heating.Furthermore,Shellac ELIS coating could withstand abrasion and hold performance when compared with other ELIS coatings.

关键词： Bionic Wax particles Edible Hydrophobic Shellac

Nature-inspired Polysaccharide-based Aerogel for Oil–water Separation

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Journal of Bionic Engineering 2023年第5期20卷 1956-1966页

作者： Ye Fu Shulun Ai zhiguang guo Weimin Liu Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials Hubei UniversityWuhan430062China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou730000China

Oily wastewater pollution is an urgent problem to be solved.Complicated preparation process,toxic hydrophobic modifiers and poor mechanical properties limit the application of polysaccharide-based aerogel in oil–water separation.Inspired by the Strider’s Leg structure in nature,an eco-friendly and reusable polysaccharide-based composite aerogel was prepared by hydrophobic modification with zein for efficient oil–water separation.The introduction of hydrophobic zein into aerogel by simple immersion method without the use of toxic modifiers can build micro/nanostructures similar to the villi on a water strider’s leg to increase the surface roughness and the hydrophobicity.And three degradable,non-toxic and economical polysaccharides including chitosan,carboxylated cellulose nanofibers and starch were used to construct aerogel skeleton,endowing aerogel with porous structures and good mechanical properties.The resulting composite aerogel(ZOMA)showed low density(0.11 g/cm^(3)),good oil absorption capacity(9 g/g),high flux oil–water separation(5595 L m^(−2)h^(−1))and excellent oil–water separation performance(99.8%).And ZOMA still had good tensile strength and elasticity after 50 compression cycles.After 10 cycles of absorption and desorption,ZOMA aerogel remained still more than 90%of its initial absorption capacity.This study provides new insight for the design of environmentally friendly and efficient adsorbents for oil–water separation.

关键词： Polysaccharide based aerogel Zein Hydrophobic modification Oil-water separation

Lubricant self-replenishing slippery surface with prolonged service life for fog harvesting

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Friction 2022年第10期10卷 1676-1692页

作者： Yi CHEN Weimin LIU Jinxia HUANG zhiguang guo State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials Hubei UniversityWuhan 430062China

Slippery lubricant-infused surfaces exhibit excellent fog-harvesting capacities compared with superhydrophobic and superhydrophilic surfaces.However,lubricant depletion is typically unavoidable under dynamic conditions,and reinfused oil is generally needed to recover the fog-harvesting capacity.Herein,an effective strategy for delaying the depletion of lubricant to prolong the service life of fog harvesting is proposed.An ultrathin transparent lubricant self-replenishing slippery surface was fabricated via facile one-step solvent evaporation polymerization.The gel film of the lubricant self-replenishing slippery surface,which was embedded with oil microdroplets,was attached to glass slides via the phase separation and evaporation of tetrahydrofuran.The gel film GFs-150(with oil content 150 wt%of aminopropyl-terminated polydimethyl siloxane(PDMS–NH2))exhibited superior slippery and fog-harvesting performance to other gel films.Furthermore,the slippery surfaces with the trait of oil secretion triggered by mechanical stress exhibited better fog-harvesting capabilities and longer service life than surfaces without the function of lubricant self-replenishment.The lubricant self-replenishing,ultrathin,and transparent slippery surfaces reported herein have considerable potential for applications involving narrow spaces,visualization,long service life,etc.

关键词： prolonged service life lubricant self-replenishing slippery liquid-infused surfaces fog harvesting

Low friction of superslippery and superlubricity:A review

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Friction 2023年第7期11卷 1121-1137页

作者： Zijian ZHENG zhiguang guo Weimin LIU Jianbin LUO Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials Hubei UniversityWuhan 430062China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China State Key Laboratory of Tribology Tsinghua UniversityBeijing 100084China

The issues regarding energy dissipation and component damage caused by the interface friction between a friction pair attract enormous attention to friction reduction.The key-enabling technique to realize friction reduction is the use of lubricants.The lubricants smooth the contact interfaces,achieving an ultralow friction contact,which is called superslippery or superlubricity.At present,superslippery and superlubricity are two isolated research topics.There is a lack of unified definition on superslippery and superlubricity from the viewpoint of tribology.Herein,this review aims at exploring the differences and relations between superslippery and superlubricity from their origin and application scenarios.Meanwhile,the challenges for developing superslippery surface and superlubricity surface are discussed.In addition,perspectives on the interactive development of these two surfaces are presented.We hope that our discussion can provide guidance for designing superslippery or superlubricity surfaces by using varies drag-reduction technologies.

关键词： low friction superslippery superlubricity tribology lubricants

Advance in Structural Classification and Stability Study of Superamphiphobic Surfaces

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Journal of Bionic Engineering 2023年第1期20卷 366-389页

作者： Haili Zhang Deke Li Jinxia Huang zhiguang guo Weiming Liu Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials School of Materials Science and Engineering and Hubei Key Laboratory of Polymer MaterialsHubei UniversityWuhan430062China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou730000China School of Materials Engineering Lanzhou Institute of TechnologyLanzhou730050China

Superamphiphobic surfaces have great potential applications in flame resistance,anti-icing,self-cleaning,anti-adhesion,micro-flow control and so on.However,the surface durability is poor owing to the limitation of design principles.In recent years,a lot of efforts have been carried out on the morphology,structure,and stability of superamphiphobic surfaces,resulting in significant improvement in their surface superwetting properties.In this review,we present a brief classification of the morphological types of superamphiphobic surfaces and summary of the recent progress of researches on the stability of superamphiphobic surfaces.Several testing methods of mechanical and chemical stability are listed in the article,together with the characteristic results,to provide a better and more detailed understanding of the current research status on superamphiphobic surface stability,which will be of considerable importance as a reference guide for our future researches.Of course,there are still some issues that need to be addressed for the application of superamphiphobic surfaces at large scale,and this is where our future researches will be directed.Finally,we discuss the challenges as well as the prospects in the study of superamphiphobic surfaces.

关键词： Superamphiphobicity Structure Morphology Stability

Slippery Surface with Petal-like Structure for Protecting Al Alloy: Anti-corrosion, Anti-fouling and Anti-icing

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Journal of Bionic Engineering 2022年第1期19卷 83-91页

作者： Junfei Huang Jiajie Kang Jiaxu Zhang Jinxia Huang zhiguang guo School of Engineering and Technology China University of GeosciencesBeijing100083China Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials Hubei UniversityWuhan430062China State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou730000China Zhengzhou Institute China University of Geosciences(Beijing)Zhengzhou451283China

The harsh working environment affects the performance and usage life of Al and its alloys,thus limiting their application.In recent years,Slippery Liquid-infused Porous Surface(SLIPS)has attracted much attention due to excellent anti-corrosion,anti-fouling and anti-icing properties.This may be an effective way to improve the properties of Al and its alloys.Here,the SLIPS with petal-like structure was constructed on the Al alloy via simple hydrothermal reaction,Stearic Acid(STA)modification and lubricant injection.A variety of droplets(including oil-in-water emulsions)can slide on the SLIPS at a low angle,even the Sliding Angle(SA)of the water droplet is only 3°.Furthermore,the SLIPS exhibits outstanding mechanical and chemical properties.It can maintain fine oil-locking ability under high shearing force and keep slippery stability after immersion in acid/alkaline solutions.In addition,the SLIPS possesses excellent anti-corrosion,anti-fouling and anti-icing properties,which provides a new way to promote the application of Al and its alloys.Therefore,the SLIPS is expected to be an effective way to improve the properties of Al and its alloys,as well as play a role in anti-fouling and self-cleaning in construction,shipbuilding and automotive manufacturing industries,thereby expanding the practical application of Al and its alloys.

关键词： Slippery surface Al alloy Anti-corrosion Anti-fouling Anti-icing

Solar-powered miniature robot for on-site oil spill treatment under magnetic steering

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Science China Technological Sciences 2024年第7期67卷 2164-2175页

作者： WANG Ben CHEN YunRui WANG Yun JI FengTong LI HongYuan NIU ShiChao HAN ZhiWu ZHANG YaBin guo zhiguang College of Chemistry and Environmental Engineering Shenzhen University Wellcome Trust/Cancer Research UK Gurdon Institute University of Cambridge Department of Physiology Development and Neuroscience University of Cambridge State Key Laboratory for Turbulence and Complex Systems Department of Mechanics and Engineering Science Beijing Innovation Center for Engineering Science and Advanced Technology College of Engineering Peking University Key Laboratory for Bionic Engineering Ministry of Education Jilin University State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures Ministry of Education Key Laboratory of New Processing Technology for Nonferrous Metals and Materials and School of Resources Environment and Materials Guangxi University Hubei Collaborative Innovation Centre for Advanced Organic Chemical Materials Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials Hubei University

Walking on the water surface is an effective method for miniature robots to transport payloads with dramatically decreased interfacial drag. Current aquatic robots reported are generally actuated by a beam of focused light that can trigger asymmetrical deformation, enabling the directional movement through horizontal momentum transfer of photoinduced actuation force to the water. However, the operations are heavily dependent on manual manipulation of the focused light, making the long-term actuation and application of the aquatic robots in vast scenarios challenging. Herein, we developed a kind of water striderinspired robot that can autonomously manage the motion on the water surface under solar irradiation, with their direction steerable by a magnetic field. The motion of this bioinspired robot on the water surface was achieved by the use of a solar cell panel as a driving module to enable propulsive motion based on the conversion of light-electric-mechanical energies. The superhydrophobic design of its leg surfaces enables the aquatic robots with weight-bearing and drag-reducing abilities. With the assistance of magnetic navigation, the bioinspired robot can continuously and controllably locomote to the oily spill floating on the water body and collect them with high efficiency. For further demonstration, the treatment of oil spills in a campus pool with high efficiency has also been achieved. This on-site oil-spill treating strategy, taking advantage of a home-made bioinspired robot actuated by natural sunlight under magnetic steering, shows great potential applications in water-body remediation.

关键词： miniature robot superhydrophobic water strider interfacial friction magnetic actuation

A robust membrane with dual superlyophobicity for solving water-caused lubricant deterioration and water contamination

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Friction 2023年第8期11卷 1442-1454页

作者： Siyang ZHAO Chenggong XU Jiaxu ZHANG Yongmin LIANG Weimin LIU Jinxia HUANG zhiguang guo State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China School of Engineering and Technology China University of Geosciences(Beijing)Beijing 100083China State Key Laboratory of Applied Organic Chemistry Lanzhou UniversityLanzhou 730000China Ministry of Education Key Laboratory for the Green Preparation and Application of Functional Materials Hubei UniversityWuhan 430062China

Lubricants are often contaminated by water in different ways. Water-polluted lubricants extremely accelerate wear corrosion, leading to the deterioration of lubricity performance. Recently, multiphase media superwettability has been developed to endow one surface with compatible functions, such as on-demand separation of oily wastewater. However, realizing the robustness of the dual superlyophobic surface to solve water-caused lubricant deterioration and water contamination as needed remains challenges. Herein, a robust dual superlyophobic membrane is presented to realize on-demand separation for various lubricant–water emulsions. Compared to pure lubricants, the purified lubricants have equivalent tribology performance, which are much better than that of water-polluted lubricants. The as-prepared membrane maintains dual superlyophobicity, high-efficient for water or lubricant purification, and excellent tribology performance of the purified lubricant, even after immersion in hot liquids for 24 h, multicycle separation, and sandpaper abrasion for 50 cycles. Water-polluted lubricant extremely accelerates wear corrosion to promote catalytic dehydrogenation of lubricants, generating too much harmful carbon-based debris. This work shows great guiding significance for recovering the tribology performance of water-polluted lubricants and purifying water by the dual superlyophobic membrane.

关键词： dual superlyophobicity lubricant water on-demand separation tribology performance