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Cancer Biology & Medicine 2022年第7期19卷 1078-1088页

作者： Jianping Dou zhigang cheng Zhiyu Han Fangyi Liu Zhen Wang Xiaoling Yu Jie Yu Ping Liang Department of Interventional Ultrasound Chinese PLA General HospitalBeijing 100853China

Objective:Thermal ablation poses challenges in the surgical resection(SR)of small hepatocellular carcinoma(HCC),and its therapeutic outcomes for larger lesions remain debated.Methods:This retrospective study evaluated 729 patients with HCC meeting the Milan criteria,who were treated with curative SR or microwave ablation(MWA)between 2008 and 2014.Overall survival(OS),cancer-specific survival(CSS),disease-free survival(DFS),and local tumor progression(LTP)were compared after propensity score matching(PSM).Co-variates associated with OS,CSS,LTP,and DFS were identified.The risk of death and tumor progression were compared.Results:During the median follow-up of 78.6 months,253 patients were included in each group after PSM.For tumors≤3.0 cm and 3.1–4.0 cm,MWA achieved comparable results in terms of OS,CSS,DFS,and LTP.For tumors 4.1–5.0 cm,MWA had lower OS,CSS,and DFS rates(all P<0.05)than SR.Higher LTP rates were observed in the MWA group for tumors 4.1–5.0 cm,although the difference was not significant(P=0.18).Complication rates(P=0.41)were similar,but MWA led to less estimated blood loss(P<0.01)and shorter postoperative hospitalization times(P<0.01).Conclusions:MWA achieved comparable long-term oncologic outcomes with SR for≤4 cm HCC,with lower complication rates and faster recovery.

关键词： Microwave surgery hepatocellular carcinoma

Performance of CH4MOD_(wetland) for the case study of different regions of natural Chinese wetland

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Journal of Environmental Sciences 2017年第7期29卷 356-369页

作者： Tingting Li Qing Zhang zhigang cheng Guocheng Wang Lijun Yu Wen Zhang LAPC Institute of Atmospheric PhysicsChinese Academy of Sciences School of Atmospheric Sciences Chengdu University of Information Technology

Reliable national estimates of CH_4 emissions from natural wetlands depend on model validation based on site observations.We therefore evaluated the performance of the CH_4 MODwetlandmodel in simulating CH_4 emissions from 11 representative wetland sites in five regions of China.Model performance analysis showed that this method effectively simulates differences in the CH_4 fluxes between different sites and regions.The model efficiency for estimating the daily CH_4 fluxes in the northeastern China（NE）,Inner Mongolia and northwestern China（NW）,the North China plain and the Middle-Lower Yangtze Plain（E） and the Qinghai Tibetan Plateau（SW） was 0.51,0.20,0.52 and 0.65,respectively.The efficiency for estimating the annual mean CH_4 fluxes in southern China（S） was 0.99.Systematic negative deviation between the simulated and observed CH_4 emissions existed in all regions,especially in the NW region,which had a mean deviation（RMD） value of-36.7%.On the national scale,the root mean square error（RMSE）,the RMD,the model efficiency（EF）between the simulated and observed seasonal values were 28.7%,-7.8% and 0.93,respectively.The CH_4 emissions showed the highest sensitivity to air temperature in the NE and SW regions,and to water table depth in the E region.Based on the sensitivity analysis,future climate warming and wetting are likely to increase the wetland CH_4 emissions at different levels in all regions of China.

关键词： CH4MOD_（wetland） Model performance China Natural wetland

Nomogram based on albumin-bilirubin grade to predict outcome of the patients with hepatitis C virus-related hepatocellular carcinoma after microwave ablation

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Cancer Biology & Medicine 2019年第4期16卷 797-810页

作者： Chao An Xin Li Xiaoling Yu zhigang cheng Zhiyu Han Fangyi Liu Jie Yu Ping Liang Department of Interventional Ultrasound State Key Laboratory of Kidney Disease The Chinese PLA General Hospital

Objective:To construct a nomogram based on the albumin-bilirubin(ALBI)grade to provide prognostic value for hepatitis C virus(HCV)-related hepatocellular carcinoma(HCC)patients who underwent ultrasound-guided percutaneous microwave ablation(US-PMWA).Methods:From April 2005 to January 2018,183 treatment-naIve patients with 251 HCV-related HCCs according to the Milan criteria received US-PMWA subsequently.The overall survival(OS)and recurrence-free survival(RFS)were compared between groups classified by ALBI grade.Cox proportional hazard regression model based on risk factors for survival and recurrence was used to construct the nomogram.Results:The cumulative OS rates at 1-,3-,5-and 10-year were 97.7%,73.6%,54.5%and 34.5%,respectively.Stratified according to ALBI grade,the 1-,3-,and 5-year OS in the ALBI grade 1 group and grade 2 group were 99.2%,92.4%,77.9% and 97.7%,52.3%,38.6%,respectively,with significant statistical difference(P<0.001).No significant statistical difference was detected in the1-,3-,and 5-year RFS rates in the ALBI grade 1 group and grade 2 group(P=0.220).The major complication rate was 1.6%.Multivariate analysis results showed age,α-fetoprotein level,tumor number,platelet count,location,Child-Turcotte-Pugh(CTP)and ALBI grade were associated with OS,which generated the nomograms.Internal validation with 1000 bootstrapped sample sets had good concordance index of 0.769(95%CI 0.699-0.839)in OS.Conclusions:This nomogram based on ALBI grade was a visualization risk model,which could provide personalized prediction of long-term outcomes for HCV-related HCC patients after US-PMWA.

关键词： Nomogram albumin-bilirubin grade hepatitis C virus hepatocellular carcinoma microwave ablation

Strengthened African Summer Monsoon in the Mid-Piacenzian

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Advances in Atmospheric Sciences 2016年第9期33卷 1061-1070页

作者： Ran ZHANG Zhongshi ZHANG Dabang JIANG Qing YAN Xin ZHOU zhigang cheng Climate Change Research Center Chinese Academy of Sciences Department of Atmospheric Science School of Environmental Studies China University of Geosciences Nansen–Zhu International Research Centre Institute of Atmospheric Physics Chinese Academy of Sciences Bjerknes Centre for Climate Research Uni Research School of Earth and Space Sciences University of Science and Technology of China Plateau Atmosphere and Environment Key Laboratory of Sichuan Province College of Atmospheric SciencesChengdu University of Information Technology

Using model results from the first phase of the Pliocene Model Intercomparison Project （PlioMIP） and four experiments with CAM4, the intensified African summer monsoon （ASM） in the mid-Piacenzian and corresponding mechanisms are analyzed. The results from PlioMIP show that the ASM intensified and summer precipitation increased in North Africa during the mid-Piacenzian, which can be explained by the increased net energy in the atmospheric column above North Africa. Further experiments with CAM4 indicated that the combined changes in the mid-Piacenzian of atmospheric CO2 concentration and SST, as well as the vegetation change, could have substantially increased the net energy in the atmospheric column over North Africa and further intensified the ASM. The experiments also demonstrated that topography change had a weak effect. Overall, the combined changes of atmospheric CO2 concentration and SST were the most important factor that brought about the intensified ASM in the mid-Piacenzian.

关键词： PlioMIE mid-Piacenzian African summer monsoon vegetation change

保留左结肠动脉腹腔镜直肠癌根治术对患者胃功能、并发症的影响

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临床普外科电子杂志 2024年第1期12卷 41-45页

作者：程志刚敦化市医院普通外科吉林敦化133700

目的探析保留左结肠动脉(leftcolicartery,LCA)腹腔镜直肠癌根治术对患者胃功能、并发症的影响。方法选取2020年12月至2023年11月敦化市医院收治的57例行腹腔镜直肠癌根治术患者,按随机数字分组法分为对照组(28例)与观察组(29例)。对照... 详细信息

目的探析保留左结肠动脉(leftcolicartery,LCA)腹腔镜直肠癌根治术对患者胃功能、并发症的影响。方法选取2020年12月至2023年11月敦化市医院收治的57例行腹腔镜直肠癌根治术患者,按随机数字分组法分为对照组(28例)与观察组(29例)。对照组患者术中不保留LCA,观察组术中保留LCA。对比两组并发症发生率、胃功能、排尿功能、肛肠动力学。结果与术前比,术后30d两组患者的胃泌素、胃动素、胃蛋白酶原Ⅰ、降钙素基因相关肽(calcitonin gene-related peptide,CGRP)水平均升高,且观察组患者的胃泌素、胃动素、胃蛋白酶原Ⅰ、CGRP水平高于对照组;与术前相比,术后30d两组患者的肛管静息压、肛管最大收缩压均降低,且观察组患者的肛管静息压、肛管最大收缩压均高于对照组,差异均有显著性(P<0.05)。术后7d两组患者的膀胱过度活动症状评分(overactive bladder symptom scale,OABSS)各项评分较术前均降低,且术后7d观察组患者的OABSS各项评分低于对照组,差异均有显著性(P<0.05)。观察组患者术后并发症总发生率低于对照组,差异有显著性(P<0.05)。结论腹腔镜根治术中保留LCA可改善直肠癌患者的肛肠动力学指标,快速恢复其胃功能与排尿功能,并降低并发症发生风险。

关键词：左结肠动脉腹腔镜直肠癌根治术胃功能并发症

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3D摊铺系统在路面高程与横坡控制中的应用

四川建材 2024年第1期50卷 161-162,165页

作者：成志刚山西路桥第五工程有限公司山西太原030006

为解决传统2D摊铺技术缺陷的问题,山西省静兴高速公路项目采用新型工艺激光测量高精度控制系统进行路面摊铺,研究表明,激光测量高精度控制系统毫米级的流动站可便捷地实现整个摊铺作业的全过程控制,可预先对道路设计的数字化模型进行检... 详细信息

为解决传统2D摊铺技术缺陷的问题,山西省静兴高速公路项目采用新型工艺激光测量高精度控制系统进行路面摊铺,研究表明,激光测量高精度控制系统毫米级的流动站可便捷地实现整个摊铺作业的全过程控制,可预先对道路设计的数字化模型进行检查,实现摊铺过程实时检测和摊铺后的复检验收,从而达到施工全过程质量控制、实时掌控摊铺工作质量的目的。

关键词：激光测量路面摊铺高程与横坡

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深度指导的无监督领域自适应语义分割

计算机辅助设计与图形学学报 2024年第1期36卷 133-141页

作者：卢加文史金龙诸皓伟孙蕴瀚成志刚江苏科技大学计算机学院镇江2120002 南京大学计算机软件新技术国家重点实验室南京210046 浙江大学软件学院杭州310058

为了提高语义分割精度,解决模型在不同数据域上泛化性差的问题,提出基于深度信息的无监督领域自适应语义分割方法.首先,深度感知自适应框架通过捕捉深度信息和语义信息的内在联系,减小不同域之间的差异;然后,设计了一个轻量级深度估计... 详细信息

为了提高语义分割精度,解决模型在不同数据域上泛化性差的问题,提出基于深度信息的无监督领域自适应语义分割方法.首先,深度感知自适应框架通过捕捉深度信息和语义信息的内在联系,减小不同域之间的差异;然后,设计了一个轻量级深度估计网络来提供深度信息,通过跨任务交互策略融合深度和语义信息,并在深度感知空间对齐源域和目标域的分布差距;最后,提出基于深度信息的域内自适应策略弥合目标域内部的分布差异,将目标域分为子源域和子目标域,并缩小子源域和子目标域分布差距.实验结果表明,所提方法在SYNTHIA-2-Cityscapes和SYNTHIA-2-Mapillary跨域任务上的平均交并比分别为46.7%和73.3%,与同类方法相比,该方法在语义分割和深度估计精度上均有显著提升.

关键词：无监督领域自适应语义分割多任务学习深度估计

Cholecystectomy is associated with higher risk of recurrence after microwave ablation of hepatocellular carcinoma:a propensity score matching analysis

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Cancer Biology & Medicine 2020年第2期17卷 478-491页

作者： Hongcai Yang Yi Yang Jianping Dou Rui Cui zhigang cheng Zhiyu Han Fangyi Liu Xiaoling Yu Xiang Zhou Jie Yu Ping Liang School of Medicine Nankai UniversityTianjin 300071China Department of Interventional Ultrasound Chinese PLA General HospitalBeijing 100853China Department of Interventional Therapy National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

Objective:To explore the association between cholecystectomy and the prognostic outcomes of patients with hepatocellular carcinoma(H CC)who underwent microwave ablation(MWA).Methods:Patients with HCC(«=921)who underwent MWA were included and divided into cholecystectomy(n=114)and non-cholecystectomy groups(n=807).After propensity score matching(PSM)at a 1:2 ratio,overall survival(OS)and disease-free survival(DFS)rates were analyzed to compare prognostic outcomes between the cholecystectomy(«=114)and non-cholecystectomy groups(n=228).Univariate and multivariate Cox analyses were performed to assess potential risk factors for OS and DFS.Major complications were also compared between the groups.Results:After matching,no significant differences between groups were observed in baseline characteristics.The 1-,3-,and 5-year OS rates were 96.5%,82.1%,and 67.1%in the cholecystectomy group,and 97.4%,85.2%,and 74.4%in the non-cholecystectomy group(P=0.396);the 1-,3-,and 5-year DFS rates were 58.4%,34.5%,and 26.6%in the cholecystectomy group,and 73.6%,44.7%,and 32.2%in the non-cholecystectomy group(P=0.026),respectively.The intrahepatic distant recurrence rate in the cholecystectomy group was significantly higher than that in the non-cholecystectomy group(P=0.026),and the local tumor recurrence and extrahepatic recurrence rates did not significantly differ between the groups(P=0.609 and P=0.879).Multivariate analysis revealed that cholecystectomy(HR=1.364,95%Cl 1.023-1.819,P=0.035),number of tumors(2 vs.1:HR=2.744,95%Cl 1.925-3.912,P

关键词： Cholecystectomy microwave ablation hepatocellular carcinoma propensity score matching

Oscillation of Surface PM2.5 Concentration Resulting from an Alternation of Easterly and Southerly Winds in Beijing： Mechanisms and Implications

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Journal of Meteorological Research 2018年第2期32卷 288-301页

作者： Zhaobin SUN Xiaoling ZHANG Xiujuan ZHAO Xiangao XIA Shiguang MIAO Ziming LI zhigang cheng Wei WEN Yixi TANG Institute of Urban Meteorology China Meteorological Administration Beijing 100089 School of Atmospheric Sciences Key Laboratory on Plateau Atmosphere and Environment of Sichuan Province Chengdu University of Information Technology Chengdu 610225 Environment Meteorology Forecast Center of Beijing-Tianjin-Hebei Beijing 100089 Key Laboratory of Middle Atmosphere and Global Environment Observation Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 College of Earth Sciences University of Chinese Academy of Sciences Beijing 100049

We used simultaneous measurements of surface PM_（2.5） concentration and vertical profiles of aerosol concentration,temperature, and humidity, together with regional air quality model simulations, to study an episode of aerosol pollution in Beijing from 15 to 19 November 2016. The potential effects of easterly and southerly winds on the surface concentrations and vertical profiles of the PM_（2.5） pollution were investigated. Favorable easterly winds produced strong upward motion and were able to transport the PM_（2.5） pollution at the surface to the upper levels of the atmosphere. The amount of surface PM_（2.5） pollution transported by the easterly winds was determined by the strength and height of the upward motion produced by the easterly winds and the initial height of the upward wind. A greater amount of PM_（2.5） pollution was transported to upper levels of the atmosphere by upward winds with a lower initial height. The pollutants were diluted by easterly winds from clean ocean air masses. The inversion layer was destroyed by the easterly winds and the surface pollutants and warm air masses were then lifted to the upper levels of the atmosphere, where they re-established a multi-layer inversion. This region of inversion was strengthened by the southerly winds, increasing the severity of pollution. A vortex was produced by southerly winds that led to the convergence of air along the Taihang Mountains. Pollutants were transported from southern–central Hebei Province to Beijing in the boundary layer. Warm advection associated with the southerly winds intensified the inversion produced by the easterly winds and a more stable boundary layer was formed. The layer with high PM_（2.5） concentration became dee-per with persistent southerly winds of a certain depth. The polluted air masses then rose over the northern Taihang Mountains to the northern mountainous regions of Hebei Province.

关键词： easterly winds southerly winds thermodynamic structure PM2.5 model simulations Beijing

Assessing the Influence of Aerosol on Radiation and Its Roles in Planetary Boundary Layer Development

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Journal of Meteorological Research 2021年第2期35卷 384-392页

作者： zhigang cheng Yubing PAN Ju LI Xingcan JIA Xinyu ZHANG Pengkun MA Qianqian WANG Junxia DOU Jingjiang ZHANG Jiannong QUAN Institute of Urban Meteorology China Meteorological AdministrationBeijing 100089

A comprehensive measurement of planetary boundary layer(PBL)meteorology was conducted at 140 and 280 m on a meteorological tower in Beijing,China,to quantify the effect of aerosols on radiation and its role in PBL development.The measured variables included four-component radiation,temperature,sensible heat flux(SH),and turbulent kinetic energy(TKE)at 140 and 280 m,as well as PBL height(PBLH).In this work,a method was developed to quantitatively estimate the effect of aerosols on radiation based on the PBLH and radiation at the two heights(140 and 280 m).The results confirmed that the weakened downward shortwave radiation(DSR)on hazy days could be attributed predominantly to increased aerosols,while for longwave radiation,aerosols only accounted for around onethird of the enhanced downward longwave radiation.The DSR decreased by 55.2 W m^(-2) on hazy days during noontime(1100–1400 local time).The weakened solar radiation decreased SH and TKE by enhancing atmospheric stability,and hence suppressed PBL development.Compared with clean days,the decreasing rates of DSR,SH,TKE,and PBLH were 11.4%,33.6%,73.8%,and 53.4%,respectively.These observations collectively suggest that aerosol radiative forcing on the PBL is exaggerated by a complex chain of interactions among thermodynamic,dynamic,and radiative processes.These findings shed new light on our understanding of the complex relationship between aerosol and the PBL.

关键词： planetary boundary layer(PBL) aerosol radiation sensible heat flux(SH) turbulence