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Petroleum Research 2023年第2期8卷 151-166页

作者： Siqi Liu Hu Jia Hongshen Wang Yanbin Liang Duansheng Shi zhichong lu Junyi Wu State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengduChina CNOOC Energy Technology&Services Limited Engineering Technology BranchTianjinChina Oil Production Technology Institute of PetroChina Dagang Oilfield Company TianjinChina

The reservoir heterogeneity of Suizhong 36-1 oilfield is very obvious,the average permeability reaches 2000mD.Long-term water injection development leads to serious water channeling in high permeability layers,resulting in ineffective circulation of injected water and reduction of oil recovery.It is urgent to form an effective EOR method.In this paper,the oil displacement effect of different combination slugs including polymer gel,polymer microsphere and surfactant is evaluated by means of conformance control and chemical flooding.Three-layer heterogeneous 3-D plate model is used for oil displacement experiment.The experimental results show that the combination slug sequentially composed of polymer gel,polymer microspheres and surfactant have the best oil displacement effect with the oil recovery increment by 21.2% after the first water flooding.In addition,using the best slug combination for two rounds flooding,the recovery factor increased by 28.2% compared with the first water flooding.This paper provides some new insights for enhanced oil recovery in strong heterogeneity reservoir.

关键词： Heterogeneity reservoir EOR Polymer gel Microsphere Surfactant Combined slug

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变压器油色谱检测技术原理及其应用

电工技术 2022年第23期 181-183页

作者：鲁志冲国网上海市电力公司超高压分公司上海201204

油色谱检测技术是进行变压器油中溶解气体分析的重要手段,能及时、有效地发现变压器潜在的故障。分析了色谱分离及气相色谱仪原理,阐述了常用的氢焰离子化检测器、热导检测器的工作原理,总结了绝缘油中溶解气体组分分析与判断的方法及... 详细信息

油色谱检测技术是进行变压器油中溶解气体分析的重要手段,能及时、有效地发现变压器潜在的故障。分析了色谱分离及气相色谱仪原理,阐述了常用的氢焰离子化检测器、热导检测器的工作原理,总结了绝缘油中溶解气体组分分析与判断的方法及改良三比值法的优点及注意事项,最后结合实例验证变压器油中溶解气体分析在判断变压器潜在故障中的重要性与准确性。

关键词：变压器油中溶解气体油色谱氢焰离子化检测器热导检测器改良三比值法

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GIS局部放电检测原理及现场应用

电力安全技术 2022年第6期24卷 60-62页

作者：鲁志冲张逸峰国网上海市电力公司检修公司上海201204

简要介绍特高频、超声波检测的原理,对时差法、声电联合定位法进行局部放电故障精准定位进行了分析,通过实例验证了检测方法的有效性以及局部放电检测在检修工作中的必要性和重要性。

关键词：局部放电检测时差法声电联合定位法

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封闭抓斗式原料库在钢铁企业中的应用

山西冶金 2012年第2期35卷 27-29,65页

作者：卢志翀中冶京城工程技术有限公储运工程技术所北京100176

介绍了封闭抓斗式原料库的工艺流程,对其结构形式以及系统装备进行了重点阐述;通过与露天料场的对比,着重分析了抓斗原料库的优缺点及适用范围,并对其发展前景进行了探讨。

关键词：环保工艺原理系统装备适用范围

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绝缘管母线中间接头的改进设计及应用

电力与能源 2022年第1期43卷 37-40,80页

作者：何梦徐楠庄璇乐佳琪鲁志冲国网上海市电力公司检修公司上海201204

环氧浇注式绝缘管中间接头处因设计缺陷和安装工艺不良等,绝缘故障频发,严重影响了电网安全稳定运行,通过分析得到引起这类故障多发的原因主要在于中间接头部位爬电比距小、易受潮。基于有限元仿真分析,改进设计了绝缘管母线中间接头,... 详细信息

环氧浇注式绝缘管中间接头处因设计缺陷和安装工艺不良等,绝缘故障频发,严重影响了电网安全稳定运行,通过分析得到引起这类故障多发的原因主要在于中间接头部位爬电比距小、易受潮。基于有限元仿真分析,改进设计了绝缘管母线中间接头,并进行相关电气型式试验。试验结果和现场应用表明:改进后的绝缘管母线中间接头增大了绝缘管母线端部、绝缘筒内壁的爬电比距,提高了防水防潮性能,大大降低了绝缘管母线中间接头部位的故障发生率。

关键词：绝缘管母线中间接头爬电比距伞裙绝缘筒

Effects of phosphate on the transport of graphene oxide nanoparticles in saturated clean and iron oxide-coated sand columns

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Journal of Environmental Sciences 2021年第5期33卷 80-92页

作者： Jiuyan Chen Weifeng Chen Taotao lu Yumeng Song Haojing Zhang Mengjie Wang Xinhai Wang zhichong Qi Minghua lu Henan International Joint Laboratory of Medicinal Plants Utilization Henan Joint International Research Laboratory of Environmental Pollution Control MaterialsEngineering Research Center for Industrial Recirculation Water Treatment of Henan ProvinceCollege of Chemistry and Chemical EngineeringHenan UniversityKaifeng 475004China Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria Nankai UniversityTianjin 300350China Ministry of Education Key Laboratory of Humid Subtropical Eco-geographical Process Fujian Provincial Key Laboratory for Plant Eco-physiologyCollege of Geographical ScienceFujian Normal UniversityFujian 350007China Department of Hydrology University of BayreuthBayreuth D-95440Germany

In this study, transport behaviors of graphene oxide(GO) in saturated uncoated(i.e., clean sand) and goethite-coated sand porous media were examined as a function of the phosphate. We found that phosphate enhanced the transport of GO over a wide range of solution chemistry(i.e., pH 5.0–9.0 and the presence of 10 mmol/L Na^(+) or 0.5 mmol/L Ca^(2+)). The results were mainly ascribed to the increase of electrostatic repulsion between nanoparticles and porous media. Meanwhile, deposition site competition induced by the retained phosphate was another important mechanism leading to promote GO transport. Interestingly, when the phosphate concentration increased from 0.1 to 1.0 mmol/L, the transportenhancement effect of phosphate in goethite-coated sand was to a much larger extent than that in clean sand. The observations were primarily related to the difference in the total mass of retained phosphate between the iron oxide-coated sand and clean sand columns, which resulted in different degrees of the electrostatic repulsion and competitive effect of phosphate. When the background solution contained 0.5 mmol/L Ca^(2+), phosphate could be bind to sand/goethite-coated sand surface by cation bridging;and consequently, promoted competition between phosphate and nanoparticles for deposition sites, which was an important mechanism for the enhanced effect of phosphate. Moreover, the DLVO theory was applicable to describe GO transport behaviors in porous media in the absence or presence of phosphate. Taken together, these findings highlight the important status and role of phosphate on the transport and fate of colloidal graphene oxide in the subsurface environment.

关键词： Graphene oxide Phosphate Goethite Transport Sand

“利沃素”治疗非酒精性脂肪性肝炎患者1例及文献复习

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中国肝脏病杂志（电子版） 2020年第2期12卷 81-85页

作者：陆志冲毛海琴张雨丁长德盐城市大丰区第三人民医院脂肪肝中心江苏盐城224100 北京大学地坛医院教学医院肝病三科北京100015 首都医科大学附属北京地坛医院肝病三科北京100015

目前,以非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)为适应证的临床治疗药物研发活跃,但尚无正式批准上市的药物。现普遍认为血清丙氨酸氨基转移酶(alanine aminotransferase,ALT)升高,伴或不伴有高胆固醇血症、高甘... 详细信息

目前,以非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)为适应证的临床治疗药物研发活跃,但尚无正式批准上市的药物。现普遍认为血清丙氨酸氨基转移酶(alanine aminotransferase,ALT)升高,伴或不伴有高胆固醇血症、高甘油三酯血症,甚至血糖水平升高的非酒精性脂肪性肝炎(non-alcoholic steatohepatitis,NASH)患者均应给予干预。生活方式改变和功能医学干预是目前的主要手段。现对1例NASH患者应用功能性医学产品"利沃素(Liversol)"治疗的临床疗效进行报道。通过对本病例的报道和相关文献的复习,以期对NASH及其干预和治疗新措施有更深入的认识。

关键词：脂肪性肝病,非酒精性利沃素丙型肝炎病毒核心蛋白结合蛋白6 病例报告

Physiological and Transcriptomic Changes During Autumn Coloration and Senescence in Ginkgo biloba Leaves

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Horticultural Plant Journal 2020年第6期6卷 396-408页

作者： Weixing Li lu Wang zhichong He Zhaogeng lu Jiawen Cui Ningtao Xu Biao Jin Li Wang Colloge of Horticulture and Plant Protection Yangzhou UniversityYangzhou 225009China

Autumn leaf senescence and coloration is a complex process and a striking natural phenomenon.Here,through biology approach integrating transcriptomic analyses in Ginkgo biloba,we determined that the content of chlorophyll decreased during leaf senescence,while carotenoid components increased until late October in the turning stage(TS)and then decreased in the yellow leaf stage(YS).Simultaneously,chlorophyll biosynthesis genes exhibited significantly lower expression levels while chlorophyll degradation genes showed increased expression from the green leaf stage(GS)to YS.However,carotenoid biosynthesis-related genes showed enhanced expression,especially in TS.An analysis of the expression of genes related to senescence demonstrated that the expression levels of most abscisic acid-and jasmonic acid-related genes,autophagy,WRKY,and NAC genes increased,whereas cytoskeleton-,photosynthesis-,and antioxidation-related genes decreased from GS to YS.Furthermore,G.biloba seedlings exogenously treated with abscisic acid,jasmonic acid,or ultraviolet-B radiation all showed obvious color variation and senescence symptoms.We used these exogenously seedlings to further validate the function of several genes involved in chlorophyll biosynthesis and senescence.Taken together,these results contribute to the elucidation of the molecular mechanisms of leaf coloration and senescence in G.biloba as well as in the identification of candidate genes involved in this process.

关键词： Ginkgo biloba Leaf senescence Leaf coloration Transcriptome Gene expression

人参皂苷Rh2改善代谢相关脂肪性肝病患者肝脂肪变

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中国肝脏病杂志（电子版） 2021年第2期13卷 58-62页

作者：丁长德陆志冲吴海艳沈惠梁金秋成军杨松盐城市大丰区第三人民医院脂肪肝中心江苏盐城224100 首都医科大学附属北京地坛医院肝病中心北京100015

目的探讨人参皂苷Rh2制剂对于代谢相关脂肪性肝病(metabolic associated fatty liver diseases,MAFLD)患者肝脏脂肪变的改善作用。方法纳入2020年6月至2020年12月期间于首都医科大学附属北京地坛医院与盐城市大丰区第三人民医院就诊的34... 详细信息

目的探讨人参皂苷Rh2制剂对于代谢相关脂肪性肝病(metabolic associated fatty liver diseases,MAFLD)患者肝脏脂肪变的改善作用。方法纳入2020年6月至2020年12月期间于首都医科大学附属北京地坛医院与盐城市大丰区第三人民医院就诊的34例MAFLD患者,根据患者意愿分为Rh2组与对照组。对照组患者(17例)给予MAFLD常规饮食运动管理及酌情保肝治疗,Rh2组患者(17例)在常规治疗基础上联合人参皂苷Rh2制剂治疗。采用独立样本t检验或Wilcoxon秩和检验评价治疗3个月患者肝脏弹性检查受控衰减指数(controlled attenuation parameter,CAP)及肝脏硬度测定(liver stiffness measurement,LSM)值下降情况。结果纳入的34例MAFLD患者中男性20例,女性14例,年龄(43.9±14.9)岁,Rh2组患者基线CAP值显著高于对照组[(299.7±26.7)dB/m vs(278.4±32.5)d B/m;t=2.095,P=0.044]。治疗3个月后,Rh2组患者CAP值下降(中位数:27.0 dB/m vs 2.0 dB/m)和LSM值下降(中位数:3.2 kPa vs 0.4 kPa)均显著优于对照组(T=364.5,P=0.021;T=398.5,P <0.001)。结论初步证据提示MAFLD患者在常规治疗基础上联合人参皂苷Rh2治疗有助于进一步改善肝脏脂肪变,尚需扩大样本量、延长疗程评价人参皂苷Rh2对MAFLD患者的疗效。

关键词：代谢相关脂肪性肝病人参皂苷Rh2 肝脂肪变受控衰减参数

电化学治疗晚期食管癌、贲门癌100例临床分析

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实用肿瘤杂志 1996年第2期11卷 63-65页

作者：陆志冲辛育龄钟耀杰中国医学基金会大丰电化学治癌中心中日友好医院中国人民解放军总参管理局医院

１９９３年７月至１９９５年７月应用电化学治疗中、晚期食管癌、贲门癌１００例，其中８７例食管癌，１３例贲门癌。Ｘ线造影病变位于胸上段１５例，中段４５例，下段２７例，贲门１３例，肿瘤侵犯食管长度３．０～５．０ｃｍ２５例，... 详细信息

１９９３年７月至１９９５年７月应用电化学治疗中、晚期食管癌、贲门癌１００例，其中８７例食管癌，１３例贲门癌。Ｘ线造影病变位于胸上段１５例，中段４５例，下段２７例，贲门１３例，肿瘤侵犯食管长度３．０～５．０ｃｍ２５例，５．１～７．０ｃｍ５０例，７．１～９．０ｃｍ１９例，＞９ｃｍ６例。８７例食管癌内，髓质型４７例，缩窄型２９例，覃伞型８例，溃疡型３例，另１３例贲门癌未分型。病理诊断：鳞癌７８例，腺癌２２例。本组无Ⅰ期（Ｔ１Ｎ０Ｍ０）病例，Ⅱ期（Ｔ２Ｎ０Ｍ０）２５例，Ⅲ期（Ｔ３Ｎ１Ｍ０）６９例，Ⅳ期（Ｔ１Ｎ２Ｍ１）６例，全组病例均有进食梗阻症状。根据ＵＩＣＣ标准评定，１００例经６～２４个月观察，其近期疗效ＣＲ１５例，ＰＲ５９例，ＮＣ１５例，ＰＤ１０例，其中ＣＲ＋ＰＲ共７５例占７５％。远期随访５７例，生存１３个月至２４个月。

关键词：食管肿瘤胃肿瘤电化学疗法临床分析