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Building the toolbox for in vivo glia-to-neuron reprogramming

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Neural Regeneration Research 2024年第6期19卷 1171-1172页

作者： Ye xie Bo Chen Departments of Ophthalmology and Neuroscience Icahn School of Medicine at Mount SinaiNew YorkNYUSA

Unlike regenerative-competent species that possess a remarkable intrinsic capacity to replenish lost neurons and restore neurocircuits spontaneously,the central nervous system in adult mammals lacks the ability to compensate for the neuronal loss caused by neurodegenerative diseases or traumatic injuries resulting in permanent loss of *** by earlier discoveries that radial glia or astrocytes isolated from the postnatal cortex can generate neurons.

关键词： injuries cortex diseases

Phonon-blockade-based multiple-photon bundle emission in a quadratically coupled optomechanical system

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Frontiers of physics 2024年第3期19卷 207-215页

作者： Ye-Jun Xu Hong xie Interdisciplinary Research Center of Quantum and Photoelectric Information Chizhou UniversityChizhou 247000China Department of Mathematics and Physics Fujian Jiangxia UniversityFuzhou 350108China

We propose a scheme to realize antibunched multiple-photon bundles based on phonon blockade in a quadratically coupled optomechanical *** adjusting the detunings to match the conditions of phonon blockade in the photon sidebands,we establish super-Rabi oscillation between zero-photon state and multiple-photon states with adjustable super-Rabi frequencies under appropriate single-phonon resonant *** the system dissipation into account,we numerically calculate the standard and generalized second-order functions of the cavity mode as well as the quantum trajectories of the state populations with Monte Carlo simulation to confirm that the emitted photons form antibunched multiple-photon ***,the desirable n-photon states are reconstructed after a direct phonon emission based on phonon blockade,and thus the single-phonon emission heralds the cascade emission of n-photon *** proposal shows that the optomechanical system can simultaneously behave as antibunched multiple-photon emitter and single-phonon *** a nonclassical source could have potential applications in quantum information science.

关键词： multiple-photon bundle emission phonon blockade optomechanical system

基于最优时段划分的区域电网多时间尺度优化调度

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广西电力 2023年第6期46卷 59-66页

作者：谢志成百色新铝电力有限公司广西百色533000

源荷联合多时间尺度优化调度对提高区域电网新能源消纳率具有重要意义,但频繁调节损害设备使用寿命。基于此,首先构建区域电网源荷多时间尺度优化调度模型,包括日前和日内2个阶段,日前以发电机为调节手段,目标为系统总运行成本最小;日... 详细信息

源荷联合多时间尺度优化调度对提高区域电网新能源消纳率具有重要意义,但频繁调节损害设备使用寿命。基于此,首先构建区域电网源荷多时间尺度优化调度模型,包括日前和日内2个阶段,日前以发电机为调节手段,目标为系统总运行成本最小;日内以电解铝负荷和火电机组为调节手段,目标为日前-日内系统运行成本最小;其次根据新能源出力波动频率的快慢,基于Fisher时段划分方法对多时间尺度优化模型的时间尺度的长短进行分割,然后以系统运行成本最小为目标,求解源荷最优调控指令。最后以某一实际电网为算例进行仿真验证,结果表明所提模型能够有效降低系统运行成本,减少设备调节次数,保证电网安全经济运行。

关键词：源荷联合优化多时间尺度优化时段划分电解铝负荷区域电网

Progress and prospect of Pt-based catalysts for electrocatalytic hydrogen oxidation reactions

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Nano Research 2024年第3期17卷 960-981页

作者： Xu Zhang Ying xie Lei Wang Key Laboratory of Functional Inorganic Material Chemistry Ministry of Education of the People’s Republic of ChinaHeilongjiang UniversityHarbin 150080China

To achieve the goals of the peak carbon dioxide emissions and carbon neutral,the development and utilization of sustainable clean energy are extremely *** fuel cells are an important system for converting hydrogen energy into electrical ***,the slow hydrogen oxidation reaction(HOR)kinetics under alkaline conditions has limited its ***,elucidating the catalytic mechanism of HOR in acidic and alkaline media is of great significance for the construction of highly active and stable *** terms of practicality,Pt is still the primary choice for commercialization of fuel *** the above basis,we first introduced the hydrogen binding energy theory and bifunctional theory used to describe the HOR activity,as well as the pH *** that,the rational design strategies of Pt-based HOR catalysts were systematically classified and summarized from the perspective of activity *** addition,we further emphasized the importance of theoretical simulations and in situ characterization in revealing the HOR mechanism,which is crucial for the rational design of ***,the practical application of Pt-based HOR catalysts in fuel cells was also *** closing,the current challenges and future development directions of HOR catalysts were *** review will provide a deep understanding for exploring the mechanism of highly efficient HOR catalysts and the development of fuel cells.

关键词： Pt-based catalysts hydrogen oxidation reaction(HOR) electrocatalytic mechanism hydrogen binding energy theory bifunctional theory

Finite-size-induced non-Hermitian phase transitions in real space

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Science China(Physics,Mechanics & Astronomy) 2024年第11期67卷 105-111页

作者： Hongfei Wang Biye xie Wei Ren Department of Physics International Center for Quantum and Molecular StructuresShanghai UniversityShanghai 200444China School of Science and Engineering The Chinese University of Hong KongShenzhen 518172China

While non-Hermiticity provokes intriguing phenomena without Hermitian counterparts, e.g., the skin effect and the breakdown of bulk-boundary correspondence, attracting extensive attention both in fundamental physics and device engineering, the role of finite sizes therein remains elusive. Here, we propose a class of finite-size-induced non-Hermitian phase transitions, relying upon higher-order topological invariants associated with real-space wave functions. The phase diagrams for general non-Hermitian chiral models are further acquired to demonstrate our topological definition. Such phase transitions are elucidated qualitatively by an effective intercell coupling alteration that depends on finite sizes in respective directions. Besides, we mimic these phenomena by analogizing the circuit Laplacian in finite-size electric circuits with nonreciprocal couplings. The resultant admittance spectra agree with our theoretical predictions. Our findings shed light on the finite-size mechanism of non-Hermitian topological phase transitions and pave the way for applications in switching and sensing.

关键词： non-Hermitian phase transitions finite-size effects higher-order topological invariants

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钒钛磁铁矿高效综合利用新工艺研究

钢铁钒钛 2020年第5期41卷 14-21页

作者：谢志诚胡兵胡佩伟武汉科技大学资源与环境工程学院湖北武汉430081 中冶长天国际工程有限责任公司湖南长沙410205 国家烧结球团装备系统工程技术研究中心湖南长沙410205 冶金矿产资源高效利用与造块湖北省重点实验室湖北武汉430081

为实现钒钛磁铁矿低温还原、铁粉高值化利用及富钒钛料清洁利用,提出了磨选除杂—矿、煤、钠盐混合—直接还原—磨选—二次还原铁粉—钠法提钒的新工艺。结果表明,对钒钛磁铁精矿进行磨选处理,能够有效去除杂质,为后续生产优质铁粉和高... 详细信息

为实现钒钛磁铁矿低温还原、铁粉高值化利用及富钒钛料清洁利用,提出了磨选除杂—矿、煤、钠盐混合—直接还原—磨选—二次还原铁粉—钠法提钒的新工艺。结果表明,对钒钛磁铁精矿进行磨选处理,能够有效去除杂质,为后续生产优质铁粉和高效提钒打下基础。钠盐的加入可以大幅降低直接还原温度,改善还原效果。一次还原铁粉经磨选—二次还原,得到品位为98.72%的二次还原铁粉,其化学成分和工艺性能全面达到行业一级铁粉标准;富钒钛料经钠化氧化焙烧—水浸—酸性铵盐沉钒—煅烧脱氨可获得纯度98.12%的V2O5产品,浸出渣经稀硫酸浸出可获得TiO2品位49.61%的富钛料。在所选条件下,从磨选除杂后的钒钛磁铁矿精矿到二次还原铁粉、V2O5产品和富钛料的铁、钒、钛的总回收率分别为90.75%、82.71%、89.63%。

关键词：钒钛磁铁矿直接还原磨选综合利用

Robust AUC maximization for classification with pairwise confidence comparisons

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Frontiers of Computer Science 2024年第4期18卷 73-83页

作者： Haochen SHI Mingkun xie Shengjun HUANG College of Computer Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 211106China College of Electronic and Information Engineering Nanjing University of Aeronautics and AstronauticsNanjing 211106China MIIT Key Laboratory of Pattern Analysis and Machine Intelligence Nanjing 211106China

Supervised learning often requires a large number of labeled examples,which has become a critical bottleneck in the case that manual annotating the class labels is *** mitigate this issue,a new framework called pairwise comparison(Pcomp)classification is proposed to allow training examples only weakly annotated with pairwise comparison,i.e.,which one of two examples is more likely to be *** previous study solves Pcomp problems by minimizing the classification error,which may lead to less robust model due to its sensitivity to class *** this paper,we propose a robust learning framework for Pcomp data along with a pairwise surrogate loss called *** provides an unbiased estimator to equivalently maximize AUC without accessing the precise class ***,we prove the consistency with respect to AUC and further provide the estimation error bound for the proposed *** studies on multiple datasets validate the effectiveness of the proposed method.

关键词： method pairwise weakly

Analytical model for the sealant performance of tunnel gasketed joints based on multi-scale contact and percolation theories

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Underground Space 2024年第1期14卷 319-337页

作者： Jiachong xie Xin Huang Guolong Jin Department of Geotechnical Engineering College of Civil EngineeringTongji UniversityShanghai 200092China State Key Laboratory of Geotechnical and Underground Engineering Ministry of EducationShanghai 200092China College of Civil Engineering&Architecture Xinjiang UniversityUrumqi 830047China China Shipbuilding NDRI Engineering Co. Ltd.Shanghai 200063China

The localised leakage in shield tunnels that mainly occurs at segment joints may induce other defects,which threatens operational *** obtain a universal solution for the sealant performance of gasketed joints,we proposed a novel analytical model based on the multiscale contact and percolation theories,in which the obtained percolation pressure and interfacial separation can be utilized to derive the critical water leakage pressure and leakage *** evolutionary process of leakage was divided into three stages(i.e.,the percolation,leakage and breakdown),which explicitly reveal the progressive hydraulic deterioration of gasketed *** gaskets still own partial waterproof capacity until the end of the leakage stage due to the remaining contact pressure at surface *** proposed model was first verified by several sets of experimental data,based on which the determination of three key model parameters(i.e.,self-sealing slope,sealing coefficient,and expel pressure)were discussed in *** parametric study indicates that the waterproof capacity is significantly affected by the joint opening,offset,and the surface roughness of the *** variation in waterproof capacity with joint opening is mainly due to the nonlinearity of the gasket’s modulus and self-sealing *** increase in joint offset can result in a lower waterproof capacity as well as a larger leakage ***’s surface roughness affects the percolation pressure and interfacial separation,which contributes to the long-term sealant performance.

关键词： Shield tunnel Gasketed joint Sealant performance Hydraulic deterioration Percolation theory Surface roughness Leakage rate

Expression analysis of the R2R3-MYB gene family in upland cotton and functional study of GhMYB3D5 in regulating Verticillium wilt resistance

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Journal of Integrative Agriculture 2024年第10期23卷 3294-3310页

作者： Jie Liu zhicheng Wang Bin Chen Guoning Wang Huifeng Ke Jin Zhang Mengjia Jiao Yan Wang Meixia xie Yanbin Li Dongmei Zhang Xingyi Wang Qishen Gu Zhengwen Sun Liqiang Wu Xingfen Wang Zhiying Ma Yan Zhang State Key Laboratory of North China Crop Improvement and Regulation/North China Key Laboratory for Germplasm Resources Ministry of Education/College of AgronomyHebei Agricultural UniversityBaoding 071001China

Improving plant resistance to Verticillium wilt(VW),which causes massive losses in Gossypium hirsutum,is a global *** plants need to efficiently allocate their limited energy resources to maintain a balance between growth and ***,few transcriptional regulators specifically respond to Verticillium dahliae and the underlying mechanism has not been identified in *** this study,we found that the that expression of most R2R3-MYB members in cotton is significantly changed by *** infection relative to the other MYB *** novel R2R3-MYB transcription factor(TF)that specifically responds to ***,GhMYB3D5,was ***3D5 was not expressed in 15 cotton tissues under normal conditions,but it was dramatically induced by *** *** functionally characterized its positive role and underlying mechanism in VW *** *** infection,the up-regulated GhMYB3D5 bound to the GhADH1 promoter and activated *** addition,GhMYB3D5 physically interacted with GhADH1 and further enhanced the transcriptional activation of ***,the transcriptional regulatory module GhMYB3D5-GhADH1 then promoted lignin accumulation by improving the transcriptional levels of genes related to lignin biosynthesis(GhPAL,GhC4H,Gh4CL,and GhPOD/GhLAC)in cotton,thereby enhancing cotton VW *** results demonstrated that the GhMYB3D5 promotes defense-induced lignin accumulation,which can be regarded as an effective way to orchestrate plant immunity and growth.

关键词： cotton Verticillium wilt resistance GhMYB3D5 GhADH1 transcriptional regulatory module