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Communications in Theoretical Physics 2008年第1期49卷 221-224页

作者： zhong zhi-Rong su Wan-Jun Department of Electronic Science and Applied Physics Puzhou University Puzhou 350002 China

A scheme is presented to generate even-photon state based on resonant interaction between ladder-type three-level atoms with a single-mode field. In the scheme, a sequence of suitably prepared ladder-type three-level atoms are orderly sent through a single-mode cavity initiaJly in vacuum state. The detection of a J1 the atoms in the ground states collapses the cavity to the desired state. The scheme is based on the resonant interaction of atoms with the cavity, and thus the required interaction time can be greatly shortened. This is important in view of decoherence.

关键词： even photon state resonant interaction ladder-type atom

Effects of Soluble Ions on Hydration of Calcined Flue Gas Desulphurization Gypsum

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Chinese Journal of Chemical Physics 2020年第6期33卷 764-768,I0003页

作者： Fu-xing Lin Yan-chi zhong Shu-feng Yan Bi-fan Lin Jian-hua Wang zhi-zhong su College of Resources and Chemical Engineering Sanming UniversitySanming 365004China Fujian Engineering Research Center for Advanced Fluorine-containing Materials Sanming 365004China CAS Key Laboratory of Soft Matter Chemistry Department of Polymer Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China

The influence of various water soluble cations(K^+,Na^+,Ca^2+,Mg^2+)on the hydration of calcined flue gas desulphurization gypsum was *** results show that all cations but Ca^2+can accelerate the hydration of *** final crystal size is not largely influenced by different salts,except for Na^+,where the giant crystal with length of>130μm is *** study clarifies the influence of different ions on the hydration of bassanite,which could provide sufficient guide for the pre-treatment of original flue gas desulphurization gypsum before actual application.

关键词： Bassanite Flue gas desulphurization Hydration Soluble ions

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重庆市人口与经济发展空间耦合分布研究

人文地理 2017年第2期32卷 122-128页

作者：官冬杰谭静张梦婕蓝忠志苏维词重庆交通大学建筑与城市规划学院重庆400074 重庆师范大学地理与旅游学院重庆400047 贵州科学院山地资源研究所贵阳550001

本文基于2001—2012年重庆市各个区县的人口和经济数据,计算重庆市各区县的人口地理集中度和经济地理集中度并结合耦合指数,分析人口分布与经济分布耦合特征与人口与经济空间分布类型,并运用Geoda、Arc GIS软件对重庆各个区县人口与经... 详细信息

本文基于2001—2012年重庆市各个区县的人口和经济数据,计算重庆市各区县的人口地理集中度和经济地理集中度并结合耦合指数,分析人口分布与经济分布耦合特征与人口与经济空间分布类型,并运用Geoda、Arc GIS软件对重庆各个区县人口与经济的全局和局部空间自相关分析,建立人口与经济发展耦合度模型与耦合协调度模型,分析人口与经济的空间耦合度的特征。研究结果表明:1重庆市的人口与经济整体水平有较好的发展趋势,但区域发展差异明显。2人口集中度和经济集中度总体上呈现"一圈高,两翼低"的特点。32001—2012年间重庆市人口与经济耦合度总体呈上升趋势,且人口与经济间的耦合作用不断增强。

关键词：人口经济发展耦合分布重庆市

Rock fracture mechanism of buffer blasting with cushion layer at the borehole bottom

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 325-334页

作者： Xinguang Zhu Chenxi Ding Zhe sui Hong su Xu Guo School of Civil and Resources Engineering University of Science and Technology BeijingBeijing 100083China Key Laboratory for Mechanics in Fluid Solid Coupling Systems Institute of MechanicsChinese Academy of SciencesBeijing 100190China School of Mechanics and Civil Engineering China University of Mining and Technology(Beijing)Beijing 100083China School of Chemical and Blasting Engineering Anhui University of Science and TechnologyHuainan 232001China

This study primarily investigates the rock fracture mechanism of bottom cushion layer blasting and explores the effects of the bottom cushion layer on rock *** involves analyses of the evolution patterns of blasting stress,characteristics of crack distribution,and rock fracture features in the ***,blasting model experiments were carried out using the dynamic caustics principle to investigate the influence of bottom cushion layers and initiation methods on the integrity of the bottom rock *** experimental results indicate that the combined use of bottom cushion layers and inverse initiation effectively protects the integrity of the bottom rock ***,the process of stress wave propagation and dynamic crack propagation in rocks was simulated using the continuum-discontinuum element method(CDEM)and the Landau explosion source model,with varying thicknesses of bottom cushion *** numerical simulation results indicate that with increasing cushion thickness,the absorption of energy generated by the explosion becomes more pronounced,resulting in fewer cracks in the bottom rock *** illustrates the positive role of the cushion layer in protecting the integrity of the bottom rock mass.

关键词： bottom cushion layer blasting crack propagation continuum-discontinuum element method dynamic stress intensity factor

Glucocorticoid receptor signaling in the brain and its involvement in cognitive function

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Neural Regeneration Research 2025年第9期20卷 2520-2537页

作者： Chonglin su Taiqi Huang Meiyu Zhang Yanyu Zhang Yan Zeng Xingxing Chen Brain Science and Advanced Technology Institute Hubei Province Key Laboratory of Occupational Hazard Identification and ControlSchool of MedicineWuhan University of Science and TechnologyWuhanHubei ProvinceChina

The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental *** the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an important component of the hypothalamicpituitary-a d renal axis's negative feedback loop and plays a key role in regulating cognitive equilibrium and *** glucoco rticoid receptor influences cognitive processes,including glutamate neurotransmission,calcium signaling,and the activation of brain-derived neurotrophic factor-mediated pathways,through a combination of genomic and non-genomic *** interactions within the central nervous system can alter the expression and activity of the glucocorticoid receptor,there by affecting the hypothalamic-pituitary-a d renal axis and stress-related cognitive *** appropriate level of glucocorticoid receptor expression can improve cognitive function,while excessive glucocorticoid receptors or long-term exposure to glucoco rticoids may lead to cognitive *** with cognitive impairment-associated diseases,such as Alzheimer's disease,aging,depression,Parkinson's disease,Huntington's disease,stroke,and addiction,often present with dysregulation of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor *** review provides a comprehensive overview of the functions of the glucoco rticoid receptor in the hypothalamic-pituitary-a d renal axis and cognitive *** emphasizes that appropriate glucocorticoid receptor signaling fa cilitates learning and memory,while its dysregulation can lead to cognitive *** provides clues about how glucocorticoid receptor signaling can be targeted to ove rcome cognitive disability-related disorders.

关键词： brain-derived neurotrophic factor calcium signaling glucocorticoid receptor glucocorticoid glutamate transmission hypothalamic-pituitary-adrenal axis long-term potentiation neurocognitive disorders neuroplasticity stress

Sequential intraventricular injection of tigecycline and polymyxin B in the treatment of intracranial Acinetobacter baumannii infection after trauma: a case report and review of the literature

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Military Medical Research 2020年第4期7卷 497-502页

作者： Li zhong Xue-zhi Shi Lei su zhi-Feng Liu Second Clinical College of Guangzhou University of Chinese Medicine Guangzhou 510515China Department of Critical Care Medicine the First Affiliated Hospital of Guizhou University of Chinese MedicineGuiyang 550001China Department of Critical Care Medicine General Hospital of Southern Theater Command of PLAGuangzhou 510010China Key Laboratory of Hot Zone Trauma Care and Tissue Repair of PLA General Hospital of Southern Theater Command of PLAGuangzhou 510010China

Background:Intracranial infection after craniotomy is one of the most serious postoperative complications,especially multidrug-resistant(MDR)or extensively drug-resistant(XDR)bacterial meningitis,and strongly affects the prognosis of *** treatment experience regarding these infections is *** presentation:We report a case of severe intracranial infection of XDR Acinetobacter baumannii(***)that was treated by intravenous(IV)injection,sequential intraventricular(IVT)injection of tigecycline and polymyxin B,and other anti-infective *** results were obtained,and the patient was eventually discharged from the *** case is characterized by intracranial ***:The polymyxin B IV+IVT pathway is an ideal treatment strategy for XDR *** tigecycline IVT pathway is also a safe treatment option.

关键词： Intraventricular injection of tigecycline Polymyxin B Intracranial infection Acinetobacter baumannii

Single-cell and spatial omics:exploring hypothalamic heterogeneity

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Neural Regeneration Research 2025年第6期20卷 1525-1540页

作者： Muhammad Junaid Eun Jeong Lee su Bin Lim Department of Biochemistry&Molecular Biology Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Graduate School of Ajou UniversitySuwonSouth Korea Department of Brain Science Ajou University School of MedicineSuwonSouth Korea

Elucidating the complex dynamic cellular organization in the hypothalamus is critical for understanding its role in coordinating fundamental body functions. Over the past decade, single-cell and spatial omics technologies have significantly evolved, overcoming initial technical challenges in capturing and analyzing individual cells. These high-throughput omics technologies now offer a remarkable opportunity to comprehend the complex spatiotemporal patterns of transcriptional diversity and cell-type characteristics across the entire hypothalamus. Current single-cell and single-nucleus RNA sequencing methods comprehensively quantify gene expression by exploring distinct phenotypes across various subregions of the hypothalamus. However, single-cell/single-nucleus RNA sequencing requires isolating the cell/nuclei from the tissue, potentially resulting in the loss of spatial information concerning neuronal networks. Spatial transcriptomics methods, by bypassing the cell dissociation, can elucidate the intricate spatial organization of neural networks through their imaging and sequencing technologies. In this review, we highlight the applicative value of single-cell and spatial transcriptomics in exploring the complex molecular-genetic diversity of hypothalamic cell types, driven by recent high-throughput achievements.

关键词： cellular diversity hypothalamus multi-omics single-cell transcriptomics spatial transcriptomics

Expression of angiopoietins, Tie2 and vascular endothelial growth factor in angiogenesis and progression of hepatocellular carcinoma

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World Journal of Gastroenterology 2006年第26期12卷 4241-4245页

作者： zhong-Lin Zhang zhi-su Liu Quan sun Department of General surgery Zhongnan Hospital Wuhan University Wuhan 430071 Hubei Province China

AIM： TO investigate the significance of angiopoietins, Tie2 and vascular endothelial growth factor （VEGF） expression in the angiogenesis and progress of hepatocellular carcinoma （HCC）. METHODS： Fresh surgically resected specimens of HCC and noncancerous liver （NCL） tissue from 38 patients with HCC were obtained, and expression of angiopoietin-1 （Ang-1）, angiopoietin-2 （Ang-2）, Tie2, and VEGF messenger RNA （mRNA） was examined by real-time quantitative reverse transcription-polymerase chain reaction （RT-PCR）. Expression pattern of each gene in HCC and NCL tissue specimens was compared and the potential role and interaction in angiogenesis of HCC were analyzed. Genes＇ expression level and its relationship with tumor＇s clinicopathological parameters were also investigated. Immunohistochemical staining of CD34 was performed to determine the microvessel density （MVD） and Ang-2/Ang-1 ratio was calculated. Relationships between Ang-2/Ang-1 ratio, VEGF and MVD and clinicopathological features were also tested so as to evaluate their significance in the progression of HCC. REsuLTS： Ang-2 and VEGF mRNAs in HCC were significantly higher than those in NCL tissue （P 〈 0.05）, whereas the Ang-1 and Tie2 mRNAs showed no statistical significance （P 〉 0.05）, though slightly lower level of Ang-1 mRNA in HCC was observed. Ang-2/ Ang-1 ratio and VEGF were both positively correlated to MVD. The Ang-2/Ang-1 ratio, Ang-2 and VEGF were all associated with tumor＇s clinicopathological parameters （P 〈 0.05） except for histological grades （P 〉 0.05）. Ang-1 and Tie2 levels in different clinicopathological groups were not significantly different （P 〉 0.05）. CONCLUSION： Dominant Ang-2 expression against Ang-1 through Tie2 receptor in the presence of VEGF plays a critical role in initiating early neovascularization and transformation of noncancerous liver to hepatocellular carcinoma. Its consequently constant operation in formed HCC induces further angiogenesis and progression of HCC.

关键词： Hepatocellular carcinoma Vascular endothelial growth factor Angiopoietin Tie2 Angiogenesis Neovascularization

Nonclasssical Properties in Two-Mode Fields Resonantly Interacting with a Three-Level -Type Atom

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Communications in Theoretical Physics 2007年第4X期48卷 721-724页

作者： su Wan-Jun ZENG Xiao-Meng zhong zhi-Rong Department of Electronic Science and Applied Physics Fuzhou University Fuzhou 350002 China

Some noclassical properties in electromagnetic field are investigated for the interaction of two-modes initially taken in coherent-state representation with the three-level -type atom, such as squeezing properties and violation of the Cauchy-Schwartz inequality. The enhancement of field squeezing is found by selective atomic measurement. The Cauchy-Schwartz inequality is violated by the application of the classical field followed by detection in excited state.

关键词： nonclassical properties two-mode coherent states resonant interaction selective atomic measurement

Teleporation of an Arbitrary Two-Particle State Without Bell-State Measurement in Cavity QED

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Communications in Theoretical Physics 2008年第6期49卷 1596-1598页

作者： zhong zhi-Rong YE Sai-Yun su Wan-Jun Department of Electronic Science and Applied Physics Fuzhou University Fuzhou 350002 China

A scheme for approximately conditional teleportation of an arbitrary two-particle state without Bell-state measurement in cavity QED is presented. The scheme involves four two-level atoms and two single-mode cavities. The detection of atoms 3 and 4 collapses the atoms 1 and 2 to the initial state of atoms 3 and 4, while the cavity fields left in the vacuum state. The probability of success and the fidelity of our scheme are 0.125 and 0.98, respectively.

关键词： teleportation arbitrary two-particle state