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Science China Chemistry 2025年第01期 257-263页

作者： Jiapian Huang Chenxin Wang xu Wang Xiaoyu Zhou Wei Xiao Jie Wu School of Pharmaceutical and Chemical Engineering & Institute for Advanced Studies Taizhou University State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences School of Chemistry and Chemical Engineering Henan Normal University

The generation of various β-chiral sulfones bearing chiral cyclic sulfinamides through photoredox-catalyzed sulfur dioxide insertion with asymmetric radical cyclization is described. This method features a broad substrate scope and excellent stereospecificity. Computational studies reveal that the dispersion interaction between sulfinyl group and CH2SO2Ph group plays a crucial role in the stereoselectivity control.

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Vision-based docking system for an aromatic-hydrocarbon-inspired reconfigurable robot

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Science China(Technological Sciences) 2024年第6期67卷 1798-1816页

作者： xing FangYi xu Cheng LIU JinGuo xuE zhiHui State Key Laboratory of Robotics Shenyang Institute of AutomationChinese Academy of SciencesShenyang110016China School of Automation and Electrical Engineering Shenyang Ligong UniversityShenyang110158China Institutes for Robotics and Intelligent Manufacturing Chinese Academy of SciencesShenyang110169China University of Chinese Academy of Sciences Beijing100049China

Aromatic hydrocarbons generally refer to compounds containing benzene *** types of isomers can be formed by replacing hydrogen atoms on the benzene *** this paper,an aromatic-hydrocarbon-inspired modular robot(AHIMR)is *** robot can be reassembled into different configurations suitable for various task requirements.A vision-based docking system is designed for the *** system primarily consists of two stages:a remote guidance stage and a precise docking *** the remote guidance stage,an object module is identified using an illumination adaptive target recognition algorithm,and then the active module moves to the docking area through communication with *** the precise docking stage,the active module calculates the relative pose with the object module using a perspective-n-point method and dynamically adjusts its posture to *** this process,a Kalman filter is used to reduce target occlusion and jitter *** addition,the docking system feasibility is verified via several simulation *** module docking accuracy is controlled within 0.01 m,which meets the reconfiguration task requirements of the *** the AHIMR submodule docking experiment,the active module accurately moves to the expected position with a docking success rate of 95%.

关键词： modular robot reconfiguration aromatic hydrocarbon autonomous docking visual identification

Pathophysiological mechanisms of chronic compressive spinal cord injury due to vascular events

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Neural Regeneration Research 2023年第4期18卷 790-796页

作者： Zhen-Xiao Ren Jing-Hui xu xing Cheng Gui-xing xu Hou-Qing Long Guangdong Provincial Key Laboratory of Orthopaedics and Traumatology/Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Department of Neurosurgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Cervical spondylotic myelopathy is the main cause of non-traumatic spinal cord injury,with chronic static and/or dynamic compressive spinal cord injury as the unique *** the progression of this condition,the microvascular network is compressed and destroyed,resulting in ischemia and *** main pathological changes are inflammation,damage to the blood spinal cord barriers,and cell apoptosis at the site of *** have confirmed that vascular regeneration and remodeling contribute to neural repair by promoting blood flow and the reconstruction of effective circulation to meet the nutrient and oxygen requirements for nerve *** decompression is the most effective clinical treatment for this condition;however,in some patients,residual neurological dysfunction remains after *** revascularization during compression and after decompression is therefore complementary to surgical *** this review,we summarize the progress in research on chronic compressive spinal cord injury,covering both physiological and pathological changes after compression and decompression,and the regulatory mechanisms of vascular injury and repair.

关键词： angiogenesis cervical spondylotic myelopathy hypoxia inflammation ischemia spinal cord injury surgical decompression

Study on the Jehol Biota:Recent advances and future prospects

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Science China Earth Sciences 2020年第6期63卷 757-773页

作者： xing xu Zhonghe ZHOU Yuan WANG Min WANG Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesCAS Center for Excellence in Life and PaleoenvironmentBeijing 100044China

The Jehol Biota is an Early Cretaceous terrestrial fossil assemblage of paramount significance,and its core distribution areas are western Liaoning,northern Hebei,and southeastern Inner *** with a research history of more than 150 years,it started yielding important fossils until early 1990s,which include feathered dinosaurs,early birds,early mammals,flower-visiting insects,and early *** discoveries have implications for understanding the origins and early evolution of several major organismal groups,as well as the origin and initial formation of modern terrestrial *** review presents a brief introduction of the major discoveries,research history,and current understanding of this biota,and also provides future prospects for studying the Jehol Biota.

关键词： Jehol Biota Early Cretaceous Terrestrial ecosystem Origin Evolution

Tranylcypromine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss

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Neural Regeneration Research 2025年第5期20卷 1483-1494页

作者： Xihang Chen zhifeng Chen Menghua Li Weiwei Guo Shuolong Yuan Liangwei xu Chang Lin Xi Shi Wei Chen Shiming Yang Senior Department of Otolaryngology Head and Neck Surgery Chinese PLA General HospitalChinese PLA Medical SchoolBeijingChina State Key Laboratory of Hearing and Balance Science BeijingChina National Clinical Research Center for Otolaryngologic Diseases BeijingChina Key Laboratory of Hearing Science Ministry of EducationBeijingChina Beijing Key Laboratory of Hearing Impairment Prevention and Treatment BeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Otolaryngology Head and Neck Surgery The 940th Hospital of Joint Logistics Support Force of Chinese PLALanzhouGansu ProvinceChina Key Laboratory of Tropical Biological Resources of Ministry of Education School of Pharmaceutical SciencesHainan UniversityHaikouHainan ProvinceChina Academician Workstation of Hainan University School of Pharmaceutical SciencesYazhou BaySanyaHainan ProvinceChina

Noise-induced hearing loss is the primary non-genetic factor contributing to auditory ***,there are currently no effective pharmacological interventions for patients with noise-induced hearing ***,we present evidence suggesting that the lysine-specific demethylase 1 inhibitor–tranylcypromine is an otoprotective agent that could be used to treat noise-induced hearing loss,and elucidate its underlying regulatory *** established a mouse model of permanent threshold shift hearing loss by exposing the mice to white broadband noise at a sound pressure level of 120 d B for 4 *** found that tranylcypromine treatment led to the upregulation of Sestrin2(SESN2)and activation of the autophagy markers light chain 3B and lysosome-associated membrane glycoprotein 1 in the cochleae of mice treated with *** noise exposure group treated with tranylcypromine showed significantly lower average auditory brainstem response hearing thresholds at click,4,8,and 16 k Hz frequencies compared with the noise exposure group treated with *** findings indicate that tranylcypromine treatment resulted in increased SESN2,light chain 3B,and lysosome-associated membrane glycoprotein 1 expression after noise exposure,leading to a reduction in levels of 4-hydroxynonenal and cleaved caspase-3,thereby reducing noise-induced hair cell ***,immunoblot analysis demonstrated that treatment with tranylcypromine upregulated SESN2 expression via the autophagy *** treatment also reduced the production of NOD-like receptor family pyrin domaincontaining 3(NLRP3)*** conclusion,our results showed that tranylcypromine treatment ameliorated cochlear inflammation by promoting the expression of SESN2,which induced autophagy,thereby restricting NLRP3-related inflammasome signaling,alleviating cochlear hair cell loss,and protecting hearing *** findings suggest that inhibiting lysine-specific demethylase 1 is a

关键词： 4-hydroxynonenal apoptosis autophagy cleaved caspase-3 inflammation NOD-like receptor family pyrin domain-containing 3(NLRP3) noise-induced hearing loss oxidative stress Sestrin2 tranylcypromine

One-step anti-superbug finishing of cotton textiles with dopamine-menthol

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Journal of Materials Science & Technology 2021年第10期69卷 79-88页

作者： Jiangqi xu Zixu Xie Fanglin Du xing Wang Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing Laboratory of Biomedical MaterialsCollege of Life Science and TechnologyBeijing University of Chemical TechnologyBeijing100029China

In this work,the one-step stereochemical antimicrobial finishing of cotton textiles(CT)was achieved by the oxidative copolymerization of a dopamine-menthol derivative(DAM)and dopamine(DA).The obtained DAM-modified CT(P(DAM-co-DA)-CT)exhibited broad-spectrum microbial anti-adhesion properties against bacteria(*** and ***),including superbugs(MRSA and VREF),and fungi(***,***,*** and ***).Because of its unique stereochemical antimicrobial mechanism,the obtained P(DAM-co-DA)-CT is a non-releasing antimicrobial material that causes no skin sensitization and exhibits good *** coating was also found to enhance the UVresistant and mechanical properties of the ***,it displayed durable washing fastness and antimicrobial properties after the endurance of 30 laundering *** observed achievements provide a broader understanding of stereochemical antimicrobial surfaces and endow this method with wider applications.

关键词： Anti-superbug Antifungal Cotton textiles Dopamine-menthol One-step finishing Stereochemical antimicrobial material

An Exact Generalized Test for Homogeneity of Inverse Gaussian Scale Parameters

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Acta Mathematicae Applicatae Sinica 2019年第4期35卷 761-769页

作者： xu-hua LIU xing-zhong xu Wei-yan MU Department of Mathematics China Agricultural University Beijing 100083 China College of Mathematics Beijing Institute of Technology Beijing 100081 China School of Science Beijing University of Civil Engineering and Architecture Beijing 100044 China

In this paper, we propose a new generalized p-value for testing homogeneity of scale parameters λi from k independent inverse Gaussian populations. The proposed generalized p-value is proved to have exact frequentist property, and it is also invariant under the group of scale transformation. Simulation results indicate that the proposed test is better than existing approximate χ^2 test.

关键词： Inverse Gaussian distribution Generalized p-value Exact frequentist property

A Cognitive Memory-Augmented Network for Visual Anomaly Detection

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IEEE/CAA Journal of Automatica Sinica 2021年第7期8卷 1296-1307页

作者： Tian Wang xing xu Fumin Shen Yang Yang the Center for Future Multimedia and School of Computer Science and Engineering University of Electronic Science and Technology of China(UESTC)Chengdu 611731China the Center for Future Multimedia and School of Computer Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731 the Institute of Electronic and Information Engineering of UESTC in Guangdong Dongguan 523808China

With the rapid development of automated visual analysis,visual analysis systems have become a popular research topic in the field of computer vision and automated *** analysis systems can assist humans to detect anomalous events(e.g.,fighting,walking alone on the grass,etc).In general,the existing methods for visual anomaly detection are usually based on an autoencoder architecture,i.e.,reconstructing the current frame or predicting the future ***,the reconstruction error is adopted as the evaluation metric to identify whether an input is abnormal or *** flaws of the existing methods are that abnormal samples can also be reconstructed *** this paper,inspired by the human memory ability,we propose a novel deep neural network(DNN)based model termed cognitive memory-augmented network(CMAN)for the visual anomaly detection *** proposed CMAN model assumes that the visual analysis system imitates humans to remember normal samples and then distinguishes abnormal events from the collected ***,in the proposed CMAN model,we introduce a memory module that is able to simulate the memory capacity of humans and a density estimation network that can learn the data *** reconstruction errors and the novelty scores are used to distinguish abnormal events from *** addition,we develop a two-step scheme to train the proposed model so that the proposed memory module and the density estimation network can cooperate to improve *** experiments evaluated on various popular benchmarks show the superiority and effectiveness of the proposed CMAN model for visual anomaly detection comparing with the state-of-the-arts *** implementation code of our CMAN method can be accessed at https://***/CMANcode/CMAN_pytorch.

关键词： Cognitive computing density estimation memory visual analysis systems visual anomaly detection.

A polaron theory of quantum thermal transistor in nonequilibrium three-level systems

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Chinese Physics B 2020年第8期29卷 83-95页

作者： Chen Wang Da-zhi xu Department of Physics Zhejiang Normal UniversityJinhua 321004China School of Physics and Center for Quantum Technology Research Beijing Institute of TechnologyBeijing 100081China

We investigate the quantum thermal transistor effect in nonequilibrium three-level systems by applying the polarontransformed Redfield equation combined with full counting *** steady state heat currents are obtained via this unified approach over a wide region of system–bath coupling,and can be analytically reduced to the Redfield and nonequilibrium noninteracting blip approximation results in the weak and strong coupling limits,respectively.A giant heat amplification phenomenon emerges in the strong system–bath coupling limit,where transitions mediated by the middle thermal bath are found to be crucial to unravel the underlying ***,the heat amplification is also exhibited with moderate coupling strength,which can be properly explained within the polaron framework.

关键词： quantum transport open systems nonequilibrium and irreversible thermodynamics phonons or vibrational states in low-dimensional structures and nanoscale materials

Multiple dynamic bonds enable high mechanical strength and efficient room-temperature self-healable polyurethane for triboelectric nanogenerators

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Science China Chemistry 2025年

作者： Wenwen Zhang Huixia xuan Xiaofei xu Jiaming Lou Qingbao Guan Zhengwei You State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Institute of Functional Materials College of Materials Science and Engineering Shanghai Key Laboratory of Lightweight Composite Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine Donghua University

For room temperature self-healing triboelectric nanogenerators（TENGs）, the inherent contradiction between mechanical strength and self-healing properties was an urgent problem to be solved. Based on the phenol-carbamate bond, this paper proposed a strategy to design a new molecular structure and coordinate the triple dynamic bonds, which provided a feasible strategy to solve this contradiction. With polytetramethylene ether glycol（M_n= 1,000） as the soft segment in the main chain of polyurethane（PU）, meanwhile methylene diphenyl diisocyanate and 4,4′-dihydroxybiphenyl（BP） as the hard segment and chain extension agent, respectively, the combination of tetrad benzene ring endowed the resultant 4BP-PU with π-π interaction. The effective reversible dissociation and association with hydrogen bond not only bestowed 4BP-PU with high mechanical strength（16.14 MPa）, but also promoted high self-healing efficiency（94.8%） at room temperature. 4BP-PU was selected as the elastic substrate between polydimethylsiloxane and copper sheet to prepare a self-healing TENG to collect energy from natural ***, the rational molecular structure design provided new ideas for developing self-healing materials and fabricating energy harvest electronics.

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