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Magnetostratigraphy and paleoenvironmental record of late Cenozoic sediments in the Taiyuan Basin,North China

Journal of Palaeogeography 2024年第4期13卷 971-992页

作者： zhi-qiang feng Qian LI Wei Han Kun-Yuan Ma Yong-Jiang Liu Rong-Zhu Wei Yan-Wei Du Yong Lei Guang-Hui Li College of Geoscience and Geomatics Engineering Taiyuan University of Technology Shanxi Institute of Geological Survey Frontiers Science Center for Deep Ocean Multispheres and Earth System Key Lab of Submarine Geoscience and Prospecting TechniquesCollege of Manine GeosciencesOcean University of China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and Technology College of Resources and Environment Shanxi Agricultural University Department of Information Engineering Shanxi University

The Taiyuan Basin is of importance for intraplate tectonic deformation in North China and contains Cenozoic strata with a maximum thickness of 3800 m.A～853.5-m-deep borehole (ZK01) with an overall core recovery rate of 85.09%was drilled at Yuci (37°35'37?N,112°39'47?E) in the central Taiyuan Basin,to obtain high-resolution records of paleomagnetism,paleoclimatic and paleoenvironmental conditions,and depositional environment of the *** obtained magnetic polarity sequence consists of 13 normal and 12 reverse zones,which correspond to C1n-C4An.2n of the geomagnetic polarity time *** data show that the evolution of ZK01 core covers the interval from 8.1 Ma to the present,and the bottoms of Pliocene,Quaternary,and Middle Pleistocene were identified in Taiyuan Basin,with a sedimentary accumulation rate ranging from 62.5 m/Ma to 175.9 m/*** data reveal that the source rocks in the study area underwent intense weathering and the sediments mainly formed in a semi-arid and oxygen-rich *** addition,paleoclimatic changes occurred at～7 Ma,3.8 Ma,and 1.7 Ma,which can be closely related to the tectonic uplift of the Loess Plateau and Tibetan Plateau,as well as the variations in the Asian monsoon and associated regional and global climatic change.

关键词： Taiyuan Basin Core sediment Magnetostratigraphy Climate change Paleoenvironment Quaternary

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The stable planar conformation of the γ-butyrolactone ring in solution

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Chinese Chemical Letters 2010年第2期21卷 187-190页

作者： zhi qiang feng Cheng Lie Yin Institute of Materia Medica Chinese Academy of Medical Sciences Beijing 100050 China Department of Chemistry Beijing Normal University Beijing 100875 China

The conformations ofγ-butyrolactone ring in solution were deduced on the basis of ~1H NMR spectra of geminal protons of the butyrolactone ring.A series of optically pure(Z)-(-)-4-(1 -alkoxyl-1 -carbalkoxy-methylene)-... 详细信息

关键词： β-Methylene-γ-butyrolactone Planar conformation Envelope conformation

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Knowledge modeling based on interval-valued fuzzy rough set and similarity inference: prediction of welding distortion

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Journal of Zhejiang University-Science C(Computers and Electronics) 2014年第8期15卷 636-650页

作者： zhi-qiang feng Cun-gen LIU Hu HUANG Maritime College Qinzhou University State Key Laboratory of Ocean Engineering Shanghai Jiao Tong University

Knowledge-based modeling is a trend in complex system modeling technology. To extract the process knowledge from an information system, an approach of knowledge modeling based on interval-valued fuzzy rough set is presented in this paper, in which attribute reduction is a key to obtain the simplified knowledge model. Through defining dependency and inclusion functions, algorithms for attribute reduction and rule extraction are obtained. The approximation inference plays an important role in the development of the fuzzy system. To improve the inference mechanism, we provide a method of similaritybased inference in an interval-valued fuzzy environment. Combining the conventional compositional rule of inference with similarity based approximate reasoning, an inference result is deduced via rule translation, similarity matching, relation modification, and projection operation. This approach is applied to the problem of predicting welding distortion in marine structures, and the experimental results validate the effectiveness of the proposed methods of knowledge modeling and similarity-based inference.

关键词： Knowledge modeling Interval-valued fuzzy rough set Similarity-based inference Welding distortion prediction

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Liver resection for benign hepatic lesions:A retrospective analysis of 827 consecutive cases

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World Journal of Gastroenterology 2008年第47期14卷 7247-7251页

作者： zhi-qiang feng zhi-qiang Huang Li-Ning Xu Rong Liu Ai-Qun Zhang xiao-qiang Huang Wen-zhi Zhang Jia-Hong Dong Department of Hepatobiliary Surgery GeneralHospital ofPLA Beijing 100853 China

AIM:To analyze the operative and perioperative factors associated with hepatectomy of benign hepatic ***:A total of 827 condecutive cases of benign hepatic lesion undergoing hepatectomy from January 1986 to December 2005 in the Chinese PLA General Hospital were investigated retrospectively according to their medical ***:The effect of operative and perioperative factors on the outcome of patients were *** the 827 cases undergoing hepatectomy for more than 3 liver segments accounted for 22.1%,316(38.21%) required transfusion of blood products during *** average operating time was 220.59 ± 109.13 min,the average hospital stay after operation was 13.55 ± 9.38 ***-Pugh A accounted for 98.13%.The postoperative complication rate was 13.54% and the in-hospital mortality rate was 0.24%.Multivariate analysis showed that operating time(P = 0.004,OR = 1.003) and albumin value(P = 0.040,OR = 0.938) were the independent predictors of morbidity and indicated that operating time,blood transfusion,complication rate,and LOS had a trend to ***:Hepatectomy for benign hepatic lesions can be performed safely with a low morbidity and mortality,provided that it is carried out with optimized perioperative management and an innovative surgical technique.

关键词： Hepatectomy Benign hepatic lesion Perioperative

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Design, Synthesis and in vitro Evaluation of Thiazole Derivatives of Ibuprofen as Cyclooxygenase-2 Inhibitors

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Chinese Chemical Letters 2006年第3期17卷 325-328页

作者： Chang Bin GUO Zhe feng CAI Zong Ru GUO zhi qiang feng feng Ming CHU Gui-Fang CHENG feng Ming CHU Gui Fang CHENG Institute of Materia Medica Chinese Academy of Medical Science and Peking Union Medical College Beijing 100050

A series of thiazole derivatives of ibuprofen, as cyclooxygenase-2 Inhibitors, were designed, synthesized and in vitro evaluated.

关键词： Cyclooxygenase-2 (COX-2) inhibitor ibuprofen thiazole derivative.

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Synergistic effect of RhBMP-2 and bFGF on ectopic osteogenesis in mice

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Asian Pacific Journal of Tropical Medicine 2015年第1期8卷 53-59页

作者： Shu-Yuan Ma zhi-qiang feng Ren-Fa Lai zhi-Ying Zhou Zhong-Da Yin First Affiliated Hospital of Ji'nan University

Objective:To investigate the synergistic effect and mechanism of the combined application of recombinant human bone morphogenetic protein-2(rhBMP-2) and basic fibroblast growth factor(bFGF).Methods:24 KM male mice were randomly divided into 6 groups with 4 mice in each group,namely,Group A(control group),Group B(only treated with collagen),Group C(treated with2 ng bFGF+collagen).Group D(treated with 4μg rhBMP-2+collagen),Group E(treated with 4 μg rhBMP-2+2 ng bFGF+collagen) and Group F(treated with 4 μg rhBMP-2+4 ng bFGF+*** composites were implanted into the intermuscular septum of hind legs mice:whereas in control group,intermuscular septum of mice was separated and no implantation was *** observation,detection of concentration of calcium content,micro computed tomography(Micro-CT).three-dimensional reconstruction *** of bone mineral density(BMD).bone volume fraction(BVF) and trabecular thickness(***).as well as histological observation with HE staining and ALP and CD34 immumohistochemical staining were ***:Ectopic osteogenesis was found in Groups D.F and F *** difference in concentration of calcium contents was statistically significant between Groups D and E(P0.05).Micro-CT and three-dimensional reconstruction revealed continuous newborn bone substance in external surface of ectopic bone formation,and the center of bone formation did not show obvious substantial filling by bone *** differences in BMD,BVF and *** were statistically significant between Groups D and E or F(P<0.01 or <0.05).HE staining showed that in Groups D.E and *** bone substance was mainly located at the edge of ectopic bone formation,and the bone formation in Groups E and F was better than that in Group *** and CD34 immumohistochemical staining revealed the positive expression mainly at the edge of ectopic bone formation,and area of positive expression in Groups E and

关键词： BMP-2 bFCF Ectopic osteogenesis Micro-CT

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Synthesis and in vitro cytotoxic activities of sorafenib derivatives

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Chinese Chemical Letters 2014年第5期25卷 702-704页

作者： Ke Wang Yan Li Li-Jing Zhang Xiao-Guang Chen zhi-qiang feng Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation Institute of Materia MedicaChinese Academy of Medical Sciences &Peking Union Medical College State Key Laboratory of Bioactive Substances and Functions of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences &Peking Union Medical College

A series of novel sorafenib derivatives have been designed and *** cytotoxic activities of these compounds were tested in three tumor cell *** of the compounds showed potent antiproliferative activity against the tested cell lines with IC50= 0–20 mmol/*** compounds demonstrated competitive antiproliferative activities to sorafenib against all three cancer cell *** them,compound 5g demonstrated significant inhibitory activity against A549,ACHN and MDAMB-231 cell lines with IC50values of 1.29,1.99,3.11 mmol/L,respectively.

关键词： Sorafenib Antiproliferative activity A549 ACHN MDA-MB-231

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Effect of rhBMP-2 sustained-release nanocapsules on the ectopic osteogenesis process in Sprague-Dawley rats

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Asian Pacific Journal of Tropical Medicine 2013年第11期6卷 884-888页

作者： Ren-Fa Lai Ze-Jian Li zhi-Ying Zhou zhi-qiang feng Qing-Tong Zhao Department of Oral & Maxillofacial Surgery First Affiliated HospitalJinan University

Objective:To explore the effect of sustained-release recombinant human bone morphogenetic protein-2(rhBMP-2) on ectopic osteogenesis in the muscle pouches of rats through preparing rhBMP-2 sustained-release capsules by wrapping morphogenesis protein bones-2(BMP-2)using chitosan nanoparticles,and compositing collagen ***:Twenty four SpragueDawley rats were randomly divided into four groups with six rats in each group,that is Group A(control group),Group B(only treated with collagen),Group C(rhBMP-2+collagen treated group) and Group D(rhBMP-2/cs+collagen treated group).The composite materials for each group were implanted in the bilateral peroneal muscle pouches in *** peroneal muscles were only separated without implanting any materials in control *** were sacrificed 2 weeks and 4 weeks post treatment and samples were cut off for general observation,Micro CT scans and histological ***:General observation showed no new bone formation in Groups A and B mice,while new bones were formed in Groups C and D *** weeks after treatment Micro CT scans showed that The bone volume fraction(BVF),trabecular thickness(Tb. Th),bone mineral density(BMD) in Group C mice were all higher than that in Group D(P<0.05). At the fourth week,the BVK,*** and BMD were significantly higher than that at the second week(P<0.01).Conclusions:The slow-release effect of rhBMP-2/cs sustained-release capsules can significantly promote ectopic *** bone formation effect is better than that of rhBMP-2 burst-release group.

关键词： BMP-2 Micro-CT Chitosan nanoparticles Polymeric drug-loading sustainedrelease capsules Ectopic osteogenesis

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Applying the fractional derivative Zener model to fitting the time-dependent material viscoelasticity tested by nanoindentation

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Biosurface and Biotribology 2018年第2期4卷 58-67页

作者： Long Fei Wei Wei Li zhi qiang feng Jian Tao Liu School of Mechanical Engineering Southwest Jiaotong UniversityChendu 610031People's Republic of China Tribology Res earch Institute Key Laboratory for Advanced Technology of Materials of Ministry of EducationSouthwest Jiaotong UniversityChendu 610031People's Republic of China LMEE-UEVE Universite de Paris-Saclay40 rue du PelvouxEvry 91020France

Material viscoelasticity is of particular importance for polymers,biotissues and many others,due to the significant influence not only on the elastic response of structures,but also on their failure mechanism in actual *** this study,the experimental tests by nanoindentations are cate gorized according to the objective parameter combined with the indenter sha pe into four distinct cases,and the Fractional Derivative Zener model(FDZM)is employed to characterize this time-dependent *** explicit data-fitting formulas are derived to determine the relaxation modulus and creep compliance te sted with the conical and spherical inde ***,a fitting scheme is provided to facilitate the identification of these viscoelastic *** comparison with the general methods adopting the Prony series or empirical models,two silent merits present:(1)fewer model coefficients necessitate being determined based on the experimental data;(2)the relaxation modulus G(t)and the creep compliance J(t)can be obtained through one indentation test,and their exact interconversion is guaranteed as *** sets of experimental data are applied to examine the validity of the developed approach,and three more examples are adopted to demonstrate the exact interconversion between G(t)and J(t).A few concluding remarks are drawn eventually.

关键词： modulus relaxation exact

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Intermittent disturbance mechanical behavior and fractional deterioration mechanical model of rock under complex true triaxial stress paths

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International Journal of Mining Science and Technology 2024年第1期34卷 117-136页

作者： zhi Zheng Hongyu Xu Kai Zhang Guangliang feng qiang Zhang Yufei Zhao State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures Key Laboratory of Disaster Prevention and Structural Safety of Ministry of EducationCollege of Civil Engineering and ArchitectureGuangxi UniversityNanning 530004China State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan 430071China State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin China Institute of Water Resources and Hydropower ResearchBeijing 100080China State Key Laboratory for Geomechanics and Deep Underground Engineering China University of Mining and TechnologyXuzhou 221116China

Mechanical excavation,blasting,adjacent rockburst and fracture slip that occur during mining excavation impose dynamic loads on the rock mass,leading to further fracture of damaged surrounding rock in three-dimensional high-stress and even causing ***,a novel complex true triaxial static-dynamic combined loading method reflecting underground excavation damage and then frequent intermittent disturbance failure is *** triaxial static compression and intermittent disturbance tests are carried out on *** effects of intermediate principal stress and amplitude on the strength characteristics,deformation characteristics,failure characteristics,and precursors of monzogabbro are analyzed,intermediate principal stress and amplitude increase monzogabbro strength and tensile fracture *** increases in microseismic parameters during rock loading can be precursors for intermittent rock *** on the experimental result,the new damage fractional elements and method with considering crack initiation stress and crack unstable stress as initiation and acceleration condition of intermittent disturbance irreversible deformation are proposed.A novel three-dimensional disturbance fractional deterioration model considering the intermediate principal stress effect and intermittent disturbance damage effect is established,and the model predicted results align well with the experimental *** sensitivity of stress states and model parameters is further explored,and the intermittent disturbance behaviors at different f are *** study provides valuable theoretical bases for the stability analysis of deep mining engineering under dynamic loads.

关键词： True triaxial static and disturbance test Mechanical properties Failure mechanism and precursor Intermittent disturbance effect Fractional mechanical model

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