检索结果-南通市图书馆

Nano Research 2017年第10期10卷 3285-3294页

作者： Wenjing zhang zhi-ping zhang Xian-En zhang Feng Li State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences Wuhan 430071 China University of Chinese Academy of Sciences Beijing 100049 China National Laboratory ofBiomacromolecules CAS Center for Excellence in Biomacromolecules Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China

Protein nanocages are ideal templates for the bio-inspired fabrication of nanomaterials due to several advantageous properties. During the mineralization of nanoparticles （NPs） inside protein nanocages, most studies have employed a common strategy： seed formation inside protein nanocages followed by seeded NP growth. However, the seed formation step is restricted to gentle reaction conditions to avoid damage to the protein nanocages, which may greatly limit the spectrum of seed materials used for NP growth. We put forward a simple route to circumvent such a limitation： encapsulation of a preformed NP as the seed via self-assembly, followed by the growth of an outer metal layer. Using such a method, we succeeded in mineralizing size-tunable Au NPs and Au@Ag core-shell NPs （〈10 nm in diameter） with narrow size distributions inside the virus-based NPs of simian virus 40. The present route enables the utilization of NPs synthesized under any conditions as the starting seeds for nanomaterial growth inside protein nanocages. Therefore, it potentially leads to novel bioinorganic chimeric nanomaterials with tailorable components and structures.

关键词： protein nanocages mineralization gold nanoparticles gold-silver core-shellnanoparticles self-assembly

A New Periodic Solution to Jacobi Elliptic Functions of MKdV Equation and BBM Equation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematicae Applicatae Sinica 2012年第2期28卷 409-415页

作者： Hong-cai MA zhi-ping zhang Ai-ping DENG Department of Applied Mathematics College of Science Donghua University Shanghai 201620 China School of Mathematics and Information Sciences Henan University Kaifeng 475000 China

Based on the homogeneous balance method, the Jacobi elliptic expansion method and the auxiliary equation method, the first elliptic function equation is used to get a new kind of solutions of nonlinear evolution equations. New exact solutions to the Jacobi elliptic function of MKdV equations and Benjamin-Bona-Mahoney （BBM） equations are obtained with the aid of computer algebraic system Maple. The method is also valid for other （l＋l）-dimensional and higher dimensional systems.

关键词： (1+1)-dimensional MKdV equation BBM equation auxiliary equation method traveling wavesolution nonlinear

Synthesis,structure and property of serial p-carboxylphenoxyacetate-lanthanide coordination polymers

在线全文

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2009年第23期54卷 4296-4302页

作者： CHEN zhi CUI ping zhang Yang ZHAO Bin Department of Chemistry Nankai University Tianjin 300071 China

Four novel lanthanide-based coordination polymers, [Ln(PBDC)(HPBDC)(H2O)3] (H2PBDC=p-carboxylphenoxyacetate; Ln = La (1), Pr (2), Nd (3)) and [La2(PBDC)3(H2O)4] (4), have been prepared through hydrothermal synthetic methods. Compounds 1―3 are isomorphous and exhibit one-dimensional (1D) chain-like motifs, while compound 4 features a complicated three-dimensional (3D) architecture, which is designed and synthesized based on the inspiration from the structure characterization of compound 1. Under the similar reaction conditions, the carboxyl in compound 1 may be further deprotonated by adding the organic base of 2,2'-bipyridine. This subtle change caused a significant difference in the structures, from 1D chain of 1 to a 3D structure of 4. In addition, IR, UV-Vis, TGA and magenetic properties are also investigated in this paper.

关键词：配位聚合物合成方法结构特性稀土财产序列三维结构化合物

Photoregulation of protein plasmid expression in vitro and in vivo using BHQ caging group

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2011年第3期22卷 338-341页

作者： zhi ping zhang Ming Li Xiao Yun Chen Qing Xiang Guo Department of Chemistry University of Science and Technology of China Hpfei 230026 China Department of Chemistry Tsinghua University Beijing 100084 China

Green fluorescent protein（GFP） plasmid was caged by 8-bromo-7-hydroxyquinolinyl chromophore（BHQ） for controlling its expression with exact spatiotemporal *** vitro and in vivo experiments clearly verified that,comparing with Bhc caging, the expression level of caged GFP plasmid was dramatically decreased and then efficiently restored after subsequent photolysis.

关键词： Photoregulation Caging(uncaging) BHQ Green fluorescent protein plasmid Photolysis

Strategies for Precise Engineering and Conjugation of Antibody Targeted-nanoparticles for Cancer Therapy

在线全文

学校读者我要写书评

暂无评论

Current Medical Science 2020年第3期40卷 463-473页

作者： Yuan-yuan GUO Lu HUANG zhi-ping zhang De-hao FU Department of Pharmacy Liyuan HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430077China School of Pharmacy Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Orthopaedics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

Improvements in the diagnosis and treatment of cancer are urgently needed for use in ***(NPs)can reduce the side effects of traditional chemotherapy by sustained release of loaded drugs and increase therapeutic *** can also enhance endothelial permeation retention by size effect and its accumulation in tumor cells through passive ***,it is critical to treat cancer with a controlled targeted drug which can be specifically delivered into tumor cells and released there,resulting in a targeted therapy to eradicate tumor cells while sparing normal *** this end,antibody-mediated targeting therapy has been developed,but imperfections in antibodies(Abs)limit this ***,the combination of NPs and Abs has been highly valued in recent years,because conjugating special Abs on the surface of NPs can increase targeting efficiency,enabling selective delivery of anti-cancer drugs to tumor *** this mini-review,we would like to enumerate the strategies for the conjugation of Abs to the surface of the NPs as well as the precise engineering of targeted *** application of targeting antibody fragments in this drug delivery system will also be discussed.

关键词： cancer drug delivery nanoparticle antibody conjugation

Arabidopsis AT-hook Protein TEK Positively Regulates the Expression of Arabinogalactan Proteins for Nexine Formation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2015年第2期8卷 251-260页

作者： Qi-Shi dia Jun Zhu Xiao-Feng Xu Yue Lou Zhan-Lin zhang zhi-ping zhang Zhong-Nan Yang College of Life and Environment Sciences Shanghai Normal University Shanghai 200234 China National Key Laboratory of Plant Molecular Genetics Shanghai Institute of Plant Physiology and Ecology Chinese Academy of Sciences Shanghai 200032 China College of Agriculture Henan University of Science and Technology Luoyang 471003 China

Nexine is a conserved layer of the pollen wall. We previously reported that the nexine layer is absent in the knockout mutant of Arabidopsis TRANSPOSABLE ELEMENT SILENCING VIA AT-HOOK （TEK） gene. In this study, we investigated the molecular regulatory functions of TEK in pollen development and identified the genes encoding Arabinogalactan proteins （AGPs） as direct targets of TEK, which are essential for nexine formation. Phenotypic similarity between tek and the TEK-SRDX transgenic lines suggest that TEK plays a role in transcriptional activation in anther development. Microarray analysis identified a total of 661 genes downregulated in tek, including four genes encoding AGPs, AGP6, AGP11, AGP23, and AGP40. Electrophoretic mobility shift assays showed that TEK could directly bind the nuclear matrix attachment region （MAR） and the promoter of AGP6. Chromatin immunoprecipitation followed by PCR analysis demonstrated that TEK is enriched in the promoters of the four AGP genes. Expression of AGP6 driven by the TEK promoter in tek partially rescued both nexine formation and plant fertility. These results indicate that TEK directly reg- ulates AGP expression in the anther to control nexine layer formation. We also proposed that glycoproteins might be essential components of the nexine laver in the oollen wall.

关键词： cell walls development pollen development nexine

Photoinduced Electron Transfer in Host-Guest Complexes of Naphthalene Derivatives with p-NBCD and m-NBCD

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2006年第3期17卷 333-336页

作者： Hui Yuan HU Man Zhou ZHU zhi ping zhang Guo Tao WEN Qing Xiang GUO Department of Chemistry University of Science and Technology of China Hefei 230026

A number of naphthalene derivatives containing adamantanamine binding moiety and an （CH2）. （n = 2, 3, 4, 5, 6） spacer were prepared as electron donor. A supramolecular assembly was fabricated by the inclusion complexation of the donor substrates with the host molecules, mono-6-O-p-nitrobenzoyl-β-cyclodextrin （p-NBCD） and mono-6-O-m-nitrobenzoyl-β-cyclodextrin （m-NBCD）, in water. The fluorescence quenching in these systems was studied and detailed Stern-Volmer constants were measured. It revealed that an efficient photoinduced electron transfers （PET） between the naphthalene donors and the cyclodextrin acceptors occurred.

关键词： Cyclodextrin fluorescence quenching photoinduced electron transfer supramolecule.

Fabrication and properties of lightweight zirconia with fine closed porosity

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2024年第6期31卷 1449-1458页

作者： Yi-bo zhang Hua-zhi Gu Lv-ping Fu Ao Huang Mei-je zhang The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina

Lightweight refractory materials with thermal insulation properties and erosion resistance are advantageous for hightemperature *** zirconia refractories were prepared using starch as a pore-forming agent,basic magnesium carbonate as a stabilizer,and nano-zirconia as an *** effects of the nano-zirconia content on the pore and thermal insulation properties of the lightweight zirconia refractories were investigated based on the porosity,phase composition,microstructure,and thermal ***-zirconia was shown to have a high surface energy,and its addition effectively increased the driving force for sintering,reduced the sintering temperature,and promoted the sintering reaction,thereby reducing the apparent porosity and improving the density of the prepared *** to the superplasticity of nano-zirconia,the surface stress caused plastic deformation between particles,which increased the migration rate of grain boundaries and trapped more gas inside the material before it diffused to the surface,thereby enhancing the closed porosity of the *** presence of closed pores could extend the thermal conduction path,decrease the conduction rate,and hinder the conduction effect to effectively reduce the thermal conductivity of the *** a nano-zirconia content of 0.75 wt.%,the prepared lightweight zirconia had the highest closed porosity and the lowest thermal *** apparent porosity,closed porosity,and total porosity of the material were 2.8%,7.0%,and 9.8%,respectively,and the thermal conductivity at 800℃was 1.37 W m^(-1)k^(-1).

关键词： Sintering Nano-zirconia Closed pore:Thermal conductivity Refractory material

Thermally Conductive,Healable Glass Fiber Cloth Reinforced Polymer Composite based onβ-Hydroxyester Bonds Crosslinked Epoxy with Improved Heat Resistance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第5期42卷 643-654,I0009页

作者： Fang Chen Xiao-Yan Pang Ze-ping zhang Min-zhi Rong Ming-Qiu zhang Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education GD HPPC LabIGCMESchool of ChemistrySun Yat-sen UniversityGuangzhou510275China Guangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center Jieyang515200China

To simultaneously endow thermal conductivity,high glass transition temperature(Tg)and healing capability to glass fiber/epoxy(GFREP)composite,dynamic crosslinked epoxy resin bearing reversibleβ-hydroxyl ester bonds was reinforced with boron nitride nanosheets modified glass fiber cloth(GFC@BNNSs).The in-plane heat conduction paths were constructed by electrostatic self-assembly of polyacrylic acid treated GFC and polyethyleneimine decorated ***,the GFC@BNNSs were impregnated with the mixture of lower concentration(3-glycidyloxypropyl)trimethoxysilane grafted BN micron sheets,3,4-epoxycyclohexylmethyl 3,4-epoxycyclohexanecarboxylate and hexahydro-4-methylphthalic anhydride,which accounted for establishing the through-plane heat transport pathways and avoiding serious deterioration of mechanical *** resultant GFREP composite containing less boron nitride particles(17.6 wt%)exhibited superior in-plane(3.29 W·m^(-1)·K^(-1))and through-plane(1.16 W·m^(-1)·K^(-1))thermal conductivities,as well as high Tg of 204℃(Tg of the unfilled epoxy=177℃).The reversible transesterification reaction enabled closure of interlaminar cracks within the composite,achieving decent healing efficiencies estimated by means of tensile strength(71.2%),electrical breakdown strength(83.6%)and thermal conductivity(69.1%).The present work overcame the disadvantages of conventional thermally conductive composites,and provided an efficient approach to prolong the life span of thermally conductive GFREP laminate for high-temperature resistant integrated circuit application.

关键词： Thermally conductive composites Boron nitride High-temperature resistance β-Hydroxyl ester bond Healing

Coupling analysis method of grouting construction with deformation response of adjacent existing tunnel

在线全文

学校读者我要写书评

暂无评论

Underground Space 2024年第2期15卷 312-330页

作者： ping-wei Jiang zhi-hong zhang Hong Zheng Jin-kun Huang Key Laboratory of Urban Security and Disaster Engineering of China Ministry of Education Beijing University of TechnologyBeijing 100124China China MCC17 Group Co.LTD MaanshanAnhui 243000China School of Naval Architecture Ocean and Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China

In the new tunnel under close distance through the existing tunnel risk source,the grouting scheme developed to compensate for stratum losses is still based on empirical methods,relying on the overburden thickness of existing *** can potentially lead to an excessively high or low probability of uplift of existing *** a coupled deformation analysis method between the grouting construction and adjacent existing tunnels is of great theoretical significance for developing grouting *** order to reasonably limit the design parameters of grouting construction,based on the theory of fluid–solid coupling elastic pore-column expansion and the theory of random media,the calculation method of stratum displacement which simultaneously considers the coexistence of grout compaction expansion and permeability diffusion mode is derived,and the accuracy of the calculation method is verified by engineering *** accuracy of this calculation method was verified through engineering *** with the deformation coordination condition,the existing tunnel is regarded as an elastic Euler-Bernoulli continuous beam,and the finite element coupling balance equation of the interaction between the existing tunnel and the surrounding soil is *** on this,a coupling calculation model of the grouting construction and the deformation response of the adjacent existing tunnel is *** with three times of grouting construction examples in the shield tunneling project of Beijing Metro Line 12 under the existing airport line,the reliability of the coupling calculation model to determine the grouting construction parameters is *** calculation parameters in the coupling calculation model have clear physical meanings,which can provide a theoretical basis for the grouting design of similar risk source projects.

关键词： Grouting Close-range underpass Tunnel Random medium theory Euler-Bernoulli continuous beam