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Effectiveness of acupoint application of Xiaozhong zhitong Tie on diarrhea in patients:a retrospective cohort study in China

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Journal of Traditional Chinese Medicine 2023年第4期43卷 809-814页

作者： SHENG Song ZHANG Yanhong gao Hongyang MA Hangkun HUANG Ye LI Qingna gao Rui XU Fengqin Emergency Department Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing 100091China Institute of Clinical Pharmacology Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing 100091China Institute of Geriatrics Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing 100091China

OBJECTIVE:To provide the evidence for the efficacy of acupoint application(AA)for patients with diarrhea in a real-world ***:This study is a national multicenter retrospective cohort *** study consecutively collected outpatient medical records of patients with diarrhea from hundreds of primary hospitals nationwide registered in Chun Bo Wan Xiang cloud platform from 22nd August,2020 to 5th November,*** patients were divided into the treatment group and the control group according to patient's condition and *** control group was treated with Western Medicine,oral Chinese Medicine decoction,or *** treatment group was added with AA based on the control *** logistic regression was used to evaluate the independent efficacy of AA in diarrheal recovery on the 3rd,7th,14th and 28th *** a next step,we also performed stratified analysis and likelihood ratio test(LRT).Sensitivity analyses included propensity score matching(PSM),four PSM-related analyses and ***:The treatment group showed better efficacy than the control group on the 14th and 28th day[the 14th day:OR=1.58,95%CI(1.15,2.19),P=0.005;the 28th day:OR=2.03,95%CI(1.43,2.88),P0.05).PSM-related analyses confirmed the efficacy of AA in diarrheal *** findings are unlikely to be nullified by an unmeasured confounding variable according to the results of ***:The efficacy in the treatment group was significantly more improved than that in the control group on the 14th and 28th day.

关键词： acupoint application diarrhea real-world study retrospective cohort study Xiaozhong zhitong Tie

Event-triggered Resilient Filtering for Time-varying Systems with Randomly Occurring Nonlinearity and Missing Measurements

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Event-triggered Resilient Filtering for Time-varying Systems...

Effect of printing parameters on properties of 3D printing sand samples

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作者： ming gao Jun Hu Hongxu Zhang Department of Mathematics Harbin University of Science and Technology School of Engineering University of South Wales School of Measurement and Communication Harbin University of Science and Technology The Higher Educational Key Laboratory for Measuring & Control Technology and Instrumentations of Heilongjiang Province Harbin University of Science and Technology

This paper studies the event-triggered resilient filtering problem for a class of nonlinear systems with randomly occurring nonlinearity and missing measurements. Both the phenomena of the randomly occurring nonlinearity and the missing measurements are described by Bernoulli distributed random variables, where the occurrence probabilities could be uncertain. The event-triggered communication mechanism is introduced to save the network bandwidth during the data transmissions through the network. Additionally, the filter gain perturbations are characterized by employing the norm bounded uncertainties. The aim of the paper is to develop a robust event-triggered resilient filtering algorithm against the randomly occurring nonlinearity and missing measurements. Note that the analytical expressions of the filtering error covariance cannot be computed directly. Consequently, we derive its upper bound as an alternative way and subsequently minimize such an upper bound by properly designing the filter gain at each time step. Finally, an illustrative example is presented to show the effectiveness of the provided filtering algorithm.

关键词： Time-varying systems event-triggered mechanism randomly occurring nonlinearity missing measurements uncertain occurrence probabilities

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China Foundry 2023年第6期20卷 553-562页

作者： De-quan Shi Yin-yu Hou Gui-li gao School of Materials and Chemistry University of Shanghai for Science and TechnologyShanghai 200093China School of Mechanical and Energy Engineering Shanghai Technical Institute of Electronics and InformationShanghai 201411China

Three-dimensional sand printing(3DSP)is widely applied in sand mold *** this study,the effects of printing parameters including the resolution of printehead holes,activator content,layer thickness,and recoating speed on the tensile and bending strengths,gas evolution,and loss-on-ignition(LOI)of 3DSP samples were investigated by changing single parameter,and the dimension deviation was also *** the resolution increases,the tensile strength,bending strength,gas evolution,LOI,and deviations at X-and Y-axis directions decrease gradually while the deviation at Z-axis direction firstly increases and then *** gas evolution and LOI drops by 13.02%and 8.13%respectively,but the strength only reduces by 2.2% when the resolution increases from 0.08 mm to 0.09 *** strengths of samples rise at first and then decline while the gas evolution and LOI rise gradually with the increasing activator content or recoating *** activator content is found to have little effect on the gas evolution as the activator increases from 0.14%to 0.34%,the gas evolution is increased by 7.3%which is far less than the LOI increment of 24.1%.As the layer thickness increases,the tensile and bending strengths firstly rise and then drop while gas evolution and LOI *** the optimal printing parameters of 0.09 mm resolution,0.18%activator,0.28 mm layer thickness and 160 mm·s^(-1) recoating speed,the tensile strengths for X-sample and Y-sample are 1.48 MPa and 1.37 MPa,the bending strengths are 1.84 MPa and 1.75 MPa,the gas evolution and LOI are 9.62 mL·g^(-1) and 1.92%,respectively.

关键词： three-dimensional sand printing printing parameters mechanical properties LOI

Removal of Mercury(Hg(Ⅱ)) from Seaweed Extracts by Electrodialysis and Process Optimization Using Response Surface Methodology

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Journal of Ocean University of China 2020年第1期19卷 135-142页

作者： SUN Jiuyi SU Xin LIU Zhen LIU Junlan MA Zhun SUN Yongchao gao Xueli gao Jun College of Chemical and Environmental Engineering Shandong University of Science and TechnologyQingdao 266590China Key Laboratory of Marine Chemistry Theory and Technology Ministry of EducationCollege of Chemistry and Chemical EngineeringOcean University of ChinaQingdao 266100China

In this work,response surface methodology(RSM)was employed to model and optimize electrodialysis process for mercury(Hg(II))removal from seaweed ***-Behnken design(BBD)was utilized to evaluate the effects and the interaction of influential variables such as operating voltage,influent flow rate,initial concentration of Hg(II)on the removal rate of Hg(II).The developed regression model for removal rate response was validated by analysis of variance,and presented a good agreement of the experimental data with the quadratic equation with high value coefficient of determination value(R2=0.9913,RAdj 2=0.9678).The optimum operating parameters were determined as 7.17V operating voltage,72.54L h−1 influent flow rate and 5.04mgL−1 initial concentration of ***(II)removal rate of 76.45%was acquired under the optimum conditions,which showed good agreement with model-predicted(75.81%)*** results revealed that electrodialysis can be considered as a promising strategy for removal of Hg(II)from seaweed extracts.

关键词： electrodialysis seaweed extracts mercury removal response surface methodology Box-Behnken design

Nanosilver anchored alginate/poly(acrylic acid/acrylamide) double-network hydrogel composites for efficient catalytic degradation of organic dyes

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Frontiers of Chemical Science and Engineering 2023年第7期17卷 893-905页

作者： Fan Zhang Ce gao Shang-Ru Zhai Qing-Da An Liaoning Key Lab of Lignocellulose Chemistry and BioMaterials Liaoning Collaborative Innovation Center for Lignocellulosic BiorefineryCollege of Light Industry and Chemical EngineeringDalian Polytechnic UniversityDalian 116034China

A novel alginate/poly(acrylic acid/acrylamide)double-network hydrogel composite with silver nanoparticles was successfully fabricated using the sol–gel *** presence of carboxyl and amide groups in the network structure provided abundant active sites for complexing silver ions,facilitating the in situ reduction and confinement of silver *** batch experiments,the optimal silver loading was 20%,and 5 mmol·L^(–1) of p-nitrophenol was completely degraded in 113 s with a rate constant value of 4.057×10^(−2) s^(–1).In the tap water system and simulated seawater system,the degradation time of p-nitrophenol at the same concentration was 261 and 276 s,respectively,with a conversion rate above 99%.In the fixed-bed experiment,the conversion rate remained above 74%after 3 h at a flowing rate of 7 mL·min^(–1).After 8 cycling tests,the conversion rate remained at 98.7%.Moreover,the catalyst exhibited outstanding performance in the degradation experiment of four typical organic dyes.

关键词： double-network hydrogel dye degradation silver nanoparticles alginate

Robust Needle Localization and Enhancement Algorithm for Ultrasound by Deep Learning and Beam Steering Methods

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Journal of Computer Science & Technology 2021年第2期36卷 334-346页

作者： Jun gao Paul Liu Guang-Di Liu Le Zhang College of Computer Science Sichuan UniversityChengdu 610065China Stork Healthcare Chengdu 610000China College of Computer and Information Science Southwest UniversityChongqing 400715China West China Biomedical Big Data Center West China HospitalSichuan UniversityChengdu 610065China Pera Corporation Ltd. Beijing 100025China

Ultrasound(US)imaging is clinically used to guide needle insertions because it is safe,real-time,and low *** localization of the needle in the ultrasound image,however,remains a challenging problem due to specular reflection off the smooth surface of the needle,speckle noise,and similar line-like anatomical *** study presents a novel robust needle localization and enhancement algorithm based on deep learning and beam steering methods with three key ***,we employ beam steering to maximize the reflection intensity of the needle,which can help us to detect and locate the needle ***,we modify the U-Net which is an end-to-end network commonly used in biomedical segmentation by using two branches instead of one in the last up-sampling layer and adding three layers after the last down-sample ***,the modified U-Net can real-time segment the needle shaft region,detect the needle tip landmark location and determine whether an image frame contains the needle by one ***,we develop a needle fusion framework that employs the outputs of the multi-task deep learning(MTL)framework to precisely locate the needle tip and enhance needle shaft ***,the proposed algorithm can not only greatly reduce the processing time,but also significantly increase the needle localization accuracy and enhance the needle visualization for real-time clinical intervention applications.

关键词： ultrasound deep learning segmentation classification optimization

Association between serum resistin level and cardiovascular events in postmenopausal women with acute coronary syndrome undergoing percutaneous coronary intervention

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Chinese Medical Journal 2013年第6期126卷 1058-1062页

作者： LI Lei HAN Jiang-li MAO Jie-ming GUO Li-jun gao Wei Department of Cardiology Peking University Third Hospital Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides Ministry of Health Key Laboratory of Molecular Cardiovascular Sciences Ministry of Education Beijing 100191 China

Background As an adipocytokine, resistin has been proposed as a link between inflammation, metabolic disorder and atherosclerosis. The aim of the study is to evaluate whether serum resistin is associated with acute coronary syndrome （ACS） and major adverse cardiovascular events （MACEs） among postmenopausal women with ACS undergoing percutaneous coronary intervention （PCI）. Methods A total of 106 consecutive postmenopausal women who underwent coronary angiography for evaluation of suspected myocardial ischemia were enrolled. Pre-procedure serum resistin, inflammatory and metabolic biomarkers were measured. All participants were followed for seven years for MACEs, including cardiovascular death, recurrent nonfatal myocardial infarction, and re-PCl. Results Patients with ACS （n=69） had significantly higher resistin levels than those without coronary artery disease （CAD）（n=37）（4.61 （1.79-10.80） ng/ml vs. 2.36 （0.85-4.15） ng/ml, P=0.002）. Correlation analysis revealed positive correlations between resistin levels and inflammatory and metabolic factors （P 〈0.05）. A follow-up of a mean of 83.4 months showed that patients with ACS suffered more MACEs than those without （13.0% vs. 2.7%, P=0.05）. Adjusted for cardiovascular risks, inflammatory and metabolic factors, multiple Logistic regression analysis indicated that an elevated resistin level was an independent predictor of ACS onset （OR=1.139, 95% CI 1.024-1.268, P=0.017） and of MACEs after PCI （OR=1.099, 95% CI 1.015-1.189, P=-0.019）. To clarify the association between resistin levels and MACEs, ACS patients were divided into two subgroups on the basis of resistin levels. Compared with the low resistin subgroup （≤4.35 ng/ml, n=32）, patients in the high resistin subgroup （〉4.35 ng/ml, n=37） were more prone to suffer MACEs （21.6% vs. 3.1%, P=0.015）. Kaplan-Meier analysis showed a significantly lower event-free survival rate in ACS patients with high resistin levels than in the low resistin subgroup （78.4% vs. 96.9%, Log r

关键词： postmenopausal women resistin acute coronary syndrome major adverse cardiovascular events

Phase Transformation and Optimized Growth of TFA-MOD REBa_2Cu_3O_(7-x) Films for Coated Conductors

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Journal of Electronic Science and Technology of China 2008年第2期6卷 147-151页

作者： zhi-Yong Liu Bo gao Li-Liang Ying Feng Fan Yu-ming Lu Chuan-Bing Cai T. Thersleff B. Elke Physics Department Shanghai University 200444 Shanghai China IFW Dresden P.O. Box 270116D-01171 Dresden Germany

Several types of REBa2Cu3O7-x （REBCO, RE=Y, Ho etc.） films are prepared on single crystal substrate LaAIO3 by TFA-MOD method. The phase transformation and optimized growth conditions in the crystallization are studied. Compared with SmBCO and GdBCO, high quality YBCO and HoBCO films are relatively easy to produce. It is revealed that the YBCO grains can form at low temperatures such as 730 ℃ during the initial heating ramp. With a high heating rate of 20 K/min and a low oxygen pressure of 100 ppm, the optimum growth temperature is around 780℃, at which the films show a Jc value of 2.88 MMcm2. Further decrease of the heating rate may produce the highquality YBCO Film with a higher Jc of 3.65 MA/cm2. The temperature dependence of resistances in various magnetic fields up to 9 T shows that the present TFAMOD YBCO and HoBCO films have similar superonducting transition temperature and magnetotransport properties.

关键词： Coated conductor REBCO films,TFA-MOD.

Research progress on layered seismic anisotropy-A review

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Earthquake Research Advances 2021年第1期1卷 4-9页

作者： Shengyi Shen Yuan gao Key Laboratory of Earthquake Prediction Institute of Earthquake ForecastingChina Earthquake AdministrationBeijing100036China

Seismic anisotropy is an effective feature to study the inner structure of the *** complex tectonic area,the assumption of single-layer anisotropy is sometimes not well consistent with the observed data;thus,the assumption of multi-layered(***)anisotropy should be *** present,the main methods to study anisotropy include receiver functions,shear wave splitting from local and teleseismic events(SKS,SKKS,and PKS,hereafter collectively called XKS),P-and Pn wave travel time inversion,surface wave inversion from far-field earthquakes and ambient *** of the above method has its own advantages and ***,one or more of the above methods are often combined to characterize multi-layered anisotropy,of which the depth range of anisotropic layers are *** paper reviews the research progress of multi-layered anisotropy for the purpose of providing a basis for future seismic anisotropy investigations.

关键词： Seismic anisotropy Multi-layered anisotropy Body wave Surface wave The lithosphere and the asthenosphere The crust and the upper mantle