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External use of mirabilite to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis in children:A multicenter randomized controlled trial

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World Journal of Gastrointestinal Surgery 2023年第4期15卷 712-722页

作者： Jing-Qing Zeng Tian-Ao Zhang Kai-Hua Yang Wen-Yu Wang Jia-Yu Zhang Ya-Bin Hu jian Xiao zhi-jian gu Biao Gong Zhao-Hui Deng Department of Gastroenterology Shanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of Clinical Epidemiology and Biostatistics Shanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of Gastroenterology Shanghai Shuguang HospitalShanghai University of Traditional Chinese MedicineShanghai 200021China

BACKGROUND Acute pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography(ERCP).Currently,there is no suitable treatment for post-ERCP pancreatitis(PEP)*** studies have prospectively evaluated interventions to prevent PEP in *** To assess the efficacy and safety of the external use of mirabilite to prevent PEP in *** This multicenter,randomized controlled clinical trial enrolled patients with chronic pancreatitis scheduled for ERCP according to eligibility *** were randomly divided into the external use of mirabilite group(external use of mirabilite in a bag on the projected abdominal area within 30 min before ERCP)and blank *** primary outcome was the incidence of *** secondary outcomes included the severity of PEP,abdominal pain scores,levels of serum inflammatory markers[tumor necrosis factor-alpha(TNF-α)and serum interleukin-10(IL-10)],and intestinal barrier function markers[diamine oxidase(DAO),D-lactic acid,and endotoxin].Additionally,the side effects of topical mirabilite were *** total of 234 patients were enrolled,including 117 in the external use of mirabilite group and theother 117 in the blank *** pre-procedure and procedure-related factors were notsignificantly different between the two *** incidence of PEP in the external use ofmirabilite group was significantly lower than that in the blank group(7.7%vs 26.5%,P<0.001).The severity of PEP decreased in the mirabilite group(P=0.023).At 24 h after the procedure,thevisual analog scale score in the external use of mirabilite group was lower than that in the blankgroup(P=0.001).Compared with those in the blank group,the TNF-αexpressions weresignificantly lower and the IL-10 expressions were significantly higher at 24 h after the procedurein the external use of mirabilite group(P=0.032 and P=0.011,respectively).There were nosignificant differences in serum DAO,D-lactic acid,and endotox

关键词： Children Endoscopic retrograde cholangiopancreatography Mirabilite Chronic pancreatitis Post-endoscopic retrograde cholangiopancreatography pancreatitis Randomized controlled trial

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Karyomorphology of three species in Dipentodon(Dipentodontaceae),Perrottetia(Celastraceae),and Tapiscia(Tapisciaceae) of the order Huerteales and their phylogenetic implications

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Journal of Systematics and Evolution 2009年第4期47卷 291-296页

作者： Jing YANG jiang-Chong WU zhi-jian gu~* (Kunming Botanical Garden,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650204,China) ( Kunming Botanical Garden Kunming Institute of Botany Chinese Academy of Sciences Kunming 650204 China)

The karyomorphology of three species in Dipentodon(Dipentodontaceae),Perrottetia(Celastraceae),and Tapiscia(Tapisciaceae),namely Dipentodon sinicus,Perrottetia racemosa,and Tapiscia sinensis,was investigated in the present *** molecular research has discovered close relationships among these three genera, which has led to the establishment of the order Huerteales with Perrottetia being placed in Dipentodontaceae. Herein we report the chromosome numbers of *** and P racemosa for the first time,and present their karyotype formulas as 2n = 34 = 22 sm+12 st(***),2n = 20 = 11 m+9 sm(***),and 2n = 30 = 22 m(2SAT)+8sm(***).Asymmetry of their karyotypes is categorized to be Type 3B in ***,Type 2A in ***,and Type 2A in *** of the species shows special cytological features. Compared with Perrottetia,Dipentodon has a different basic chromosome number,a higher karyotype asymmetry, and different karyomorphology of its interphase nuclei,mitotic prophase,and ***,on the basis of these results,we have reservations regarding the suggestion of placing Dipentodon and Perrottetia together in the family Dipentodontaceae.

关键词： chromosome number Dipentodon karyomorphology Perrottetia phylogenetic relationship Tapiscia.

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Sensitivity Analysis of Thermal Properties on Numerical Simulation Results of Quenching Process

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Journal of Shanghai Jiaotong university(Science) 2011年第6期16卷 759-762页

作者：周志方顾剑锋王晓燕潘健生 Shanghai Key Laboratory of Materials Laser Processing and Modification School of Materials Science and EngineeringShanghai Jiaotong University

A three-factor three-level orthogonal test project has been designed based on the numerical simulation of a Jominy quenching *** the data scattering effects of thermal conductivity and enthalpy of tested steel,as well as the heat exchange coefficients of the cooling media,on the results have been *** results can be used as a reference for choosing the input thermal parameter in finite element simulation of quenching,and for evaluating the simulation results.

关键词： finite element simulation orthogonal test method thermal input parameters quenching

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Unlocking the future:Mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response

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World Journal of Clinical Oncology 2025年第1期16卷 43-52页

作者： zhi-jian Tang Yuan-Ming Pan Wei Li Rui-Qiong Ma jian-Liu Wang Department of Obstetrics and Gynecology Peking University People’s HospitalBeijing 100044China Cancer Research Center Beijing Chest HospitalBeijing 101149China Department of Thoracic Surgery Sichuan Provincial People's HospitalChengdu 610072Sichuan ProvinceChina

BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment *** To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural *** Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression *** genes were sourced from the MitoCarta3.0 *** discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation *** the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were *** In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy *** average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation *** average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation *** The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.

关键词： Ovarian cancer Mitochondria Prognosis Immunotherapy Neural network

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有限水深船舶水压场的实验研究

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水动力学研究与进展（A辑） 2002年第6期17卷 720-728页

作者：张志宏顾建农郑学龄龚沈光海军工程大学湖北武汉430033

对航行船舶在水底引起的压力分布进行了系统实验研究 ,分析了压力系数峰值大小、位置等参数的变化规律 ,总结出了亚临界航速和超临界航速条件下的船舶水压场分布特征。

关键词：有限水深运动船舶水压场亚临界航速超临界航速

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Vapor-assisted epitaxial growth of porphyrin-based MOF thin film for nonlinear optical limiting

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Science China Chemistry 2020年第8期63卷 1059-1065页

作者： Yi-Hong Xiao zhi-Gang gu jian Zhang State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China University of Chinese Academy of Sciences Beijing 100049China

Fabrication of metal-organic frameworks(MOFs)thin films has been an efficient way to expand their functionalities and ***,we use the vapor-assisted deposition(VAD)method to epitaxially grow a porphyrin-based MOF PCN-222 *** is,vapor source assists to deposit pre-treated precursor solution on quartz substrate to form a continuous PCN-222 ***,utilizing the post-treated encapsulation of functional carbon-based nanoparticles,the carbon nanodots(CND)and Pt doped CND(Pt/CND)are well loaded into the pores of PCN-222 film,the size(~3.1 nm)of which is highly close to the pore size of the corresponding MOF(~3.7 nm).The Z-scan results reveal that PCN-222 film exhibits high reverse saturable *** addition,encapsulation of carbon based nanodots into PCN-222 film could enhance the nonlinear optical limiting effect benefiting from the host-guest *** study serves to present both the available toolbox of thin film preparation and high potential for precise synthetic nanocomposite films in optical limiting devices.

关键词： metal-organic framework epitaxial growth porphyrin thin film nonlinear optical property

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洪镇涛语感教学的意义及其启示

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黄冈师范学院学报 2025年第1期45卷 1-5页

作者：顾之川人民教育出版社北京100081

洪镇涛先生是我国当代著名语文教育家,他的语感教学理论及其实践在语文教育界广为人知,有口皆碑。他提出“变讲堂为学堂”“变研究语言为学习语言”,继承了夏丏尊、叶圣陶、吕叔湘、张志公等老一辈语文教育家的工具论思想,对当时语文教... 详细信息

洪镇涛先生是我国当代著名语文教育家,他的语感教学理论及其实践在语文教育界广为人知,有口皆碑。他提出“变讲堂为学堂”“变研究语言为学习语言”,继承了夏丏尊、叶圣陶、吕叔湘、张志公等老一辈语文教育家的工具论思想,对当时语文教育盛行人文、忽视语言训练具有纠正时弊、拨乱反正的作用。镇涛先生给新时代教师教育的启示是:学高为师,享受语文人生;抓住根本,突出语言运用;立足课堂,提高育人智慧。

关键词：洪镇涛语感教学语文教育家学习语言语言运用

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Liquid-phase epitaxial layer by layer brushing fabrication of metalorganic frameworks films

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Nano Research 2024年第6期17卷 5698-5704页

作者： Li-Mei Chang Rui Zhai zhi-Zhou Ma jian-Dong Huang zhi-Gang gu jian Zhang College of Chemistry Fuzhou UniversityFuzhou 350108China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China University of Chinese Academy of Sciences Beijing 100049China

Development of metal-organic framework(MOF)films is of great importance to expand their ***,we report a facile and universal method of liquid-phase epitaxial(LPE)layer by layer(LBL)brushing approach for fabricating MOF films on various substrates in a high-throughput *** MOF films preparation method offers a great prospective to cost-effectively construct films with short preparation time and little reagent ***,this LBL brushing approach has been implemented successfully to assemble various MOF films,including HKUST-1,zeolitic imidazolate framework-8(ZIF-8),Cu(bdc),and Cu_(2)(L)_(2)P(L=bdc,ndc,and cam;P=dabco and bipy).Afterwards,the classic MOF HKUST-1 and ZIF-8 films were grown on sensor chip electrode and porous fiber support for good volatile organic compounds(VOCs)selective sensing and water purification *** study demonstrates that this LBL brushing preparation method can be employed to synthesize various MOF films with a variety of characteristics to realize their sensing and separation applications.

关键词： metal-organic framework porous materials layer by layer fabrication film

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Metal–Organic Framework‑Based Photodetectors

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Nano-Micro Letters 2024年第11期16卷 675-703页

作者： Jin‑Biao Zhang Yi‑Bo Tian zhi‑Gang gu jian Zhang State Key Laboratory of Structural Chemistry Structure of MatterFujian Institute of ResearchChinese Academy of SciencesFuzhouFujian 350002People’s Republic of China College of Chemistry and Materials Science Fujian Nornal UniversityFuzhou 350007FujianPeople’s Republic of China Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China Fuzhou 350108FujianPeople’s Republic of China University of Chinese Academy of Science Beijing 100049People’s Republic of China

The unique and interesting physical and chemical properties of metal–organic framework(MOF)materials have recently attracted extensive attention in a new generation of photoelectric *** this review,we summarized and discussed the research progress on MOF-based *** methods of preparing MOF-based photodetectors and various types of MOF single crystals and thin film as well as MOF composites are introduced in ***,the photodetectors applications for X-ray,ultraviolet and infrared light,biological detectors,and circularly polarized light photodetectors are ***,summaries and challenges are provided for this important research field.

关键词： Metal-organic frameworks Semiconductor Photodetectors

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六米射电望远天线反射面偏差测量

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中国科学院上海天文台年刊 1982年第0期 230-240页

作者：王丽华钱志瀚顾健星汪沪生

天线反射面与理论抛物面形状的偏差程度是影响抛物面天线效率的重要因素之一。对一个已给定的反射面,与馈源支撑结构有关的最佳吻合抛物面焦点的定位也是很重要的。本文给出与实际反射面表面最佳吻合的抛物面的焦点位置。用样板法进行测... 详细信息

天线反射面与理论抛物面形状的偏差程度是影响抛物面天线效率的重要因素之一。对一个已给定的反射面,与馈源支撑结构有关的最佳吻合抛物面焦点的定位也是很重要的。本文给出与实际反射面表面最佳吻合的抛物面的焦点位置。用样板法进行测量,并给出了六米直径射电望远镜天线反射面的表面均方根偏差。

关键词：天线反射面抛物面天线均方根值焦点位置支撑结构光程差精度分析中心线点测量馈源

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