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SOME RECENT DEVELOPMENTS IN STUDIES ON ELASTIC-PLASTIC NEAR-TIP FIELDS

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Chinese Science Bulletin 1989年第5期34卷 378-383页

作者：黄克智罗学富 Department of Engineering Mechanics Tsinghua University Beijing

Studies on near-tip fields constitute one of the central problems in fracture mechanics. This note confines attention to quasi-static steady growth of mode-Ⅰ plane strain crack growing in elastic-perfectly-plastic ma... 详细信息

关键词： elastic-plastic growing crack near-tip fields compressible materials elastic perfectly-plastic materials.

Postreperfusion syndrome during orthotopic liver transplantation:a single-center experience

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Hepatobiliary & Pancreatic Diseases International 2012年第1期11卷 34-39页

作者： Zhen-Dong Xu, Hai-Tao Xu, Hong-Bin Yuan, Hao Zhang, Rui-Hua Ji, Zui Zou, zhi-Ren fu and xue-Yin Shi Department of Anesthesiology, Huashan Hospital, fudan University, Shanghai 200040, China Department of Anesthesiology Organ Transplantation Center , Changzheng Hospital, Second Military Medical University, Shanghai 200003, China Department of Anesthesiology Huashan Hospital Fudan University Shanghai 200040 Shanghai China Department of Anesthesiology Changzheng Hospital Second Military Medical University Shanghai 200003 Shanghai China Organ Transplantation Center Changzheng Hospital Second Military Medical University Shanghai 200003 Shanghai China

BACKGROUND: Marked hemodynamic alteration, commonly referred to as postreperfusion syndrome (PRS), often occurs after revascularization of the donor organ during orthotopic liver transplantation (OLT) and is associated with poor outcomes. This study aimed to investigate the incidence, predictive factors and clinical outcomes of PRS in Chinese patients following OLT at a liver transplantation center in China. METHODS: Over a 5-year period, 330 consecutive patients who had undergone OLT for hepatocellular carcinoma or cirrhosis were included in this retrospective study. PRS was defined as a >30% decrease in the mean arterial pressure compared with that before revascularization for more than 1 minute during the first 5 minutes of graft reperfusion. The patients were divided into 2 groups according to the development of PRS: group 1 (patients with PRS, n=56) and group 2 (patients without PRS, n=274). The demographic characteristics, operative and postoperative courses, and outcomes of the patients were analyzed using SPSS version 18.0. RESULTS: Multivariate regression analysis showed that left ventricular diastolic dysfunction determined by echocardiography and prolonged cold ischemia time were the independent risk factors for PRS. More patients in group 1 showed postoperative renal dysfunction than those in group 2 (19.23% vs 8.4%). Moreover, patients in group 1 also had higher intraoperative (7.14% vs 0%) and postoperative mortalities (26.92% vs 12.04%).CONCLUSION: Left ventricular diastolic dysfunction and prolonged cold ischemia time contribute to a high incidence of PRS, which is associated with adverse outcomes in Chinese patients following OLT.

关键词： liver transplantation complications risk factors outcome

Real-world evidence on the efficacy and safety of vonoprazanamoxicillin dual therapy for Helicobacter pylori treatment in elderly patients

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World Journal of Gastroenterology 2025年第1期31卷 68-78页

作者： Wen Gao Jing-Wen Li Hui Ye xue-zhi Zhang Jian-Xiang Liu Hong Cheng Department of Gastroenterology Peking University First HospitalBeijing 100034China School of Medicine Tsinghua MedicineTsinghua UniversityBeijing 100034China Department of Traditional Chinese Medicine and Integrative Medicine Peking University First HospitalBeijing 100034China

BACKGROUND A dual therapy regimen containing amoxicillin is a common treatment option for the eradication of Helicobacter pylori(***).While substantial research supports the efficacy and safety of vonoprazan and amoxicillin(VA)dual therapy in the general population,there is still a lack of studies specifically focusing on its safety in elderly *** To evaluate efficacy and safety of VA dual therapy as first-line or rescue treatment for *** in elderly *** As a real-world retrospective study,data were collected from elderly patients aged 60 years and above who accepted VA dual therapy(vonoprazan 20 mg twice daily+amoxicillin 1000 mg thrice daily for 14 days)for *** eradication in the Department of Gastroenterology at Peking University First Hospital between June 2020 and January *** status was evaluated by^(13)C-urease breath test 6 weeks after *** adverse events(AEs)during treatment were *** In total,401 cases were ***-one cases were excluded due to loss to follow-up,lack of re-examination,or unwillingness to take *** total of 380 included cases comprised 250 who received VA dual therapy as first-line treatment and 130 who received VA dual therapy as rescue *** was successfully eradicated in 239 cases(95.6%)in the first-line treatment group and 116 cases(89.2%)in the rescue treatment *** overall incidence of AEs was 9.5%for both ***,9.2%of patients experienced an AE in the first-line treatment group and 10.0%in the rescue treatment *** patients discontinued treatment due to AE,with a discontinuation rate of 1.3%.No serious AE *** The VA dual therapy regimen as a first-line treatment and a rescue therapy was effective and safe for elderly patients aged 60 and older.

关键词： Helicobacter pylori Vonoprazan Amoxicillin Dual therapy Elderly

响应面法优化PAC与CPAM复配处理模拟废水

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过程工程学报 2017年第1期17卷 130-137页

作者：马江雅施军杨志程付雪付坤孙永军张源林安徽工业大学建筑工程学院安徽马鞍山243032 生物膜法水质净化与利用技术教育部工程研究中心安徽马鞍山243002 南京工业大学城市建设学院江苏省工业节水减排重点实验室江苏南京211800

以自制阳离子聚丙烯酰胺(CPAM)与聚合氯化铝(PAC)复配处理模拟高岭土废水,采用响应面法建立溶液透光率与各影响因素之间的Box-Behnken数学模型,优化复配应用,结果表明最佳应用条件为:PAC投加量38.39 mg/L,CPAM投加量1.09 mg/L,搅拌时间9... 详细信息

以自制阳离子聚丙烯酰胺(CPAM)与聚合氯化铝(PAC)复配处理模拟高岭土废水,采用响应面法建立溶液透光率与各影响因素之间的Box-Behnken数学模型,优化复配应用,结果表明最佳应用条件为:PAC投加量38.39 mg/L,CPAM投加量1.09 mg/L,搅拌时间9 min,p H=5.18,该条件下浊度去除率可达99%.CPAM和PAC复配可在低投加量下有效加强絮凝效果,形成的絮体密实,抗剪切能力强,沉降速度快.

关键词：响应面法阳离子聚丙烯酰胺聚合氯化铝复配絮凝

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

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Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-Yan Sun Lingyun Nie Jing Zhang xue Fang Hongmei Luo Chuanhai fu zhiyi Wei Ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

Staged dendrite suppression for high safe and stable lithium-sulfur batteries

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Journal of Energy Chemistry 2025年第1期100卷 674-683页

作者： Jun Jiang Zhenjie Lu Yanwen Ding Shujun Liu zhijie Qi Tian Tang Yunfan Zhang zhiyuan Ma Jingwen Sun Liang xue Wenyao Zhang Pan Xiong Xin Wang Junwu Zhu Yongsheng fu Key Laboratory for Soft Chemistry and functional Materials of Ministry of Education Nanjing University of Science and Technology Jiangsu Pylon Battery Co.Ltd

The unavoidable dendrite growth and shuttle effect have long been stranglehold challenges limiting the safety and practicality of lithium-sulfur ***,we propose a dual-action strategy to address the lithium dendrite issue in stages by constructing a multifunctional surface-negatively-charged nanodiamond layer with high ductility and robust puncture resistance on polypropylene （PP） *** uniformly loaded compact negative layer can not only significantly enhance electron transmission efficiency and promote uniform lithium deposition,but also reduce the formation of dendrite during early deposition *** importantly,under the strong puncture stress encountered during the deterioration of lithium dendrite growth under limiting current,the high ductility and robust puncture resistance（145.88 MPa） of as-obtained nanodiamond layer can effectively prevent short circuits caused by unavoidable lithium *** Li||Li symmetrical cells assembled with nanodiamond layer modified PP demonstrated a stable cycle of over 1000 h at 2 mA cm-2with a polarization voltage of only 29.3 ***,the negative charged layer serves as a physical barrier blocking lithium polysulfide ions,effectively mitigating capacity *** improved cells achieved a capacity decay of only 0.042%per cycle after 700 cycles at 3 C,demonstrating effective suppression of dendrite growth and capacity attenuation,showing promising prospect.

关键词： Lithium-sulfur batteries Staged dendrite suppression Shuttle effect Surface-negatively-charged nanodiamond

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甘肃省气候舒适度评价与区划

江西农业学报 2017年第10期29卷 88-92,107页

作者：郑燕清傅志军薛甜甜宝鸡文理学院/陕西省灾害监测与机理模拟重点实验室陕西宝鸡721013

利用甘肃省27个台站1960~2015年气象数据,采用温湿指数、风效指数、着衣指数等3个气候舒适度评价模型,计算得到各月舒适度等级值、时段与年综合舒适度指数;在此基础上通过GIS空间插值生成甘肃省综合舒适度空间分布图并划分了旅游气候区... 详细信息

利用甘肃省27个台站1960~2015年气象数据,采用温湿指数、风效指数、着衣指数等3个气候舒适度评价模型,计算得到各月舒适度等级值、时段与年综合舒适度指数;在此基础上通过GIS空间插值生成甘肃省综合舒适度空间分布图并划分了旅游气候区。结果表明:甘肃省各地的气候舒适期长度多在3~5个月,大部分地区从4月到10月都比较适合开展户外旅游活动,特别是5月、6月和9月,普遍达到最适宜期。冬季则普遍为不舒适期。全省可划分为河西走廊文化生态旅游区、陇中黄河文化旅游区、甘南高原民族风情区和陇东南山水文化旅游区等4个旅游气候舒适区。

关键词：气候舒适度甘肃省旅游舒适度指数

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黄尧洲从心论治老年性皮肤瘙痒症经验

世界中西医结合杂志 2018年第8期13卷 1065-1067,1071页

作者：杨彦洁徐志兰付中学中国中医科学院西苑医院北京100091

文章介绍黄尧洲教授从心论治老年性皮肤瘙痒症的经验。老年性皮肤瘙痒症病位在肌肤,但与五脏相关,尤重于心肝两脏;本质是本虚标实、虚实夹杂,心肝血虚为本,血虚生风、肝生内风、感受风燥发为瘙痒为标。故治疗此病应重视心神与肝脏的调摄... 详细信息

文章介绍黄尧洲教授从心论治老年性皮肤瘙痒症的经验。老年性皮肤瘙痒症病位在肌肤,但与五脏相关,尤重于心肝两脏;本质是本虚标实、虚实夹杂,心肝血虚为本,血虚生风、肝生内风、感受风燥发为瘙痒为标。故治疗此病应重视心神与肝脏的调摄,注重以调理心神为先,常采用宁心安神法,以安神止痒为主,重用重镇安神、养心安神药物,才能有效治疗。临床上创制养心安神止痒方,专方化裁治疗此病,体现出中医专病专方、辨病与辨证相结合的诊疗特色。

关键词：老年性皮肤瘙痒症养心安神重镇安神黄尧洲

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基于临近信标节点修正的APIT算法改进

电子设计工程 2016年第6期24卷 5-7,11页

作者：孟祥萍付志学纪秀长春工程学院电气与信息工程学院吉林长春130012 吉林省配电自动化工程研究中心吉林长春130012 长春工业大学电气与电子工程学院吉林长春130012

定位技术在无线传感器网络中占有重要的地位。近似三角形内点测试算法(APIT)是一种硬件要求低,定位性能良好的定位算法。APIT算法在节点密度较低的场合,易产生PIT误判,S-APIT算法采用面积和判断进行近似三角形内点测试,改善了APIT算法的... 详细信息

定位技术在无线传感器网络中占有重要的地位。近似三角形内点测试算法(APIT)是一种硬件要求低,定位性能良好的定位算法。APIT算法在节点密度较低的场合,易产生PIT误判,S-APIT算法采用面积和判断进行近似三角形内点测试,改善了APIT算法的PIT测试,但是在存在测距误差时,S-APIT算法并不能有效的减少PIT误判的发生。针对该问题,提出了一种将未知节点的临近信标节点作为修正节点的N-APIT算法,仿真结果表明:算法能够改善环境因素的影响,减少测距误差,改善定位精度。

关键词：无线传感器网络定位 APIT算法节点修正