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Passive activity enhances residual control ability in patients with complete spinal cord injury

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Neural Regeneration Research 2025年第8期20卷 2337-2347页

作者： Yanqing Xiao Mingming Gao Zejia He Jia Zheng Hongming bai Jia-Sheng Rao Guiyun song Wei song Xiaoguang Li Beijing Key Laboratory for Biomaterials and Neural Regeneration Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Department of Rehabilitation Evaluation China Rehabilitation Research CenterBeijingChina Cardiac Center Beijing Children’s HospitalCapital Medical UniversityBeijingChina The State Key Laboratory of Virtual Reality Technology and Systems Beihang UniversityBeijingChina Department of Rehabilitation Engineering China Rehabilitation Science InstituteBeijingChina

Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury ***,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface *** this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord *** patients with chronic complete thoracic spinal cord injury were *** electromyography data from eight major leg muscles were acquired and compared before and after the passive activity *** results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of *** the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically *** findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury.

关键词： complete spinal cord injury cycle training epidural electrical stimulation motor training passive activity physiological state spinal cord circuit surface electromyography volitional control task

Impacts of the annual cycle of background SST in the tropical Pacific on the phase and amplitude of ENSO

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 12-17页

作者： song Jiang Congwen Zhu Ning Jiang State Key Laboratory of Severe Weather(LASW) Chinese Academy of Meteorological SciencesBeijingChina College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijingChina

The dominant annual cycle of sea surface temperature(SST)in the tropical Pacific exhibits an antisymmetric mode,which explains 83.4%total variance,and serves as a background of El Niño-Southern Oscillation(ENSO).However,there is no consensus yet on its anomalous impacts on the phase and amplitude of *** on data during 1982-2022,results show that anomalies of the antisymmetric mode can affect the evolution of ENSO on the interannual scale via Bjerknes feedback,in which the positive(negative)phase of the antisymmetric mode can strengthen El Niño(La Niña)in boreal winter via an earlier(delayed)seasonal cycle transition and larger(smaller)annual *** magnitude of the SST anomalies in the equatorial eastern Pacific can reach more than±0.3◦C,regulated by the changes in the antisymmetric mode based on random sensitivity *** reveal the spatial pattern of the annual cycle associated with the seasonal phase-locking of ENSO evolution and provide new insight into the impact of the annual cycle of background SST on ENSO,which possibly carries important implications for forecasting ENSO.

关键词： Annual cycle SST anomaly Antisymmetric mode ENSO

Constraints on holographic QCD phase transitions from PTA observations

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 71-78页

作者： song He Li Li Sai Wang Shao-Jiang Wang Center for Theoretical Physics and College of Physics Jilin University School of Physical Science and Technology Ningbo University Max Planck Institute for Gravitational Physics (Albert Einstein Institute) CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of Sciences (UCAS) School of Physical Sciences University of Chinese Academy of Sciences (UCAS) Theoretical Physics Division Institute of High Energy Physics Chinese Academy of Sciences

The underlying physics of QCD phase transition in the early Universe remains largely unknown due to its strong-coupling nature during the quark-gluon plasma/hadron gas transition, yet a holographic model has been proposed to quantitatively fit the lattice QCD data while with its duration of the first-order phase transition(FoPT) left undetermined. At specific baryon chemical potential, the first-order QCD phase transition agrees with the observational constraint of baryon asymmetry. It, therefore, provides a scenario for phase transition gravitational waves(GWs) within the standard model of particle physics. If these background GWs could contribute dominantly to the recently claimed common-spectrum red noise from pulsar timing array(PTA) observations, the duration of this FoPT can be well constrained, and the associated primordial black holes are still allowed by current observations.

关键词： pulsar timing array QCD phase transition gravitational waves primordial black holes

Evolution and control of nonmetallic inclusions in FeSiB alloy

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Journal of Iron and Steel Research International 2020年第5期27卷 588-597页

作者： bai-song Li Wen-zhi Chen Yu-lin Zhao Pei Zhao Central Iron and Steel Research Institute Beijing 100081China Advanced Technology and Materials Co. Ltd.China Iron and Steel Research Institute GroupBeijing 100081China

Inclusions have a great infuence on the quality of FeSiB amorphous *** evolution behavior of inclusions was *** results show that the spherical and elliptical inclusions,consisting of Al2O3 and SiO2,mainly come from industrial pure *** inclusions of 20-30μm in pure iron were removed by foatation during the smelting process,and spherical inclusions of 1-3μm combined with deoxidized products in FeSiB melt form Al2O3·SiO2 and CaO·Al2O3·SiO2 *** inclusions accumulated on the inner wall of the nozzle during the spraying process,and others fowed out of the nozzle and remained in FeSiB amorphous *** controlling the total oxygen content in industrial pure iron to 31×10^-6,clogging on the inner wall of the nozzle can be reduced and the free surface smoothness of the amorphous ribbon can be improved.

关键词： FeSiB alloy Nonmetallic inclusion Thermodynamics Nozzle clogging

Mechanical behavior of entangled metallic wire materials-polyurethane interpenetrating composites

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Defence Technology（防务技术） 2023年第2期20卷 120-136页

作者： Xiao-yuan Zheng zhi-ying Ren Hong-bai bai Zhang-bin Wu You-song Guo College of Mechanical Engineering and Automation Fuzhou UniversityFuzhou350116China Institute of Metal Rubber&Vibration Noise Fuzhou UniversityFuzhou350116China Gongbang Vibration Control Technology Co. LtdJiangsuJiangyin214431China

Composite materials exhibit the impressive mechanical properties of high damping and stiffness,which cannot be attained by employing conventional single *** these lines,a novel material architecture is presented in this work in order to fabricate composites with enhanced mechanical *** specifically,entangled metallic wire materials were used as the active matrix,whereas polyurethane was employed as the reinforcement *** a result,an entangled metallic wire material-polyurethane composite with high damping and stiffness was prepared by enforcing the vacuum infiltration *** top of that,the mechanical properties(loss factor,energy consumption,and average stiffness)of the proposed composite materials were characterized by performing dynamic tests,and its fatigue characteristics were verified by the micro-interface bonding,as well as the macro-damage *** impact of the density,preloading spacing,loading amplitude,and exciting frequency on the mechanical properties of the composites were also thoroughly *** extracted results indicate that the mechanical properties of the composites were significantly enhanced than those of the pure materials due to the introduction of interface ***,the average stiffness of the composites was about 10 times the respective value of the entangled metallic wire ***,a rise in the loading period leads to some failure between the composite interfaces,which reduces the stiffness property but enhances the damping dissipation ***,a comprehensive dynamic mechanical model of the composites was established,while it was experimentally *** proposed composites possess higher damping features,i.e.,stiffness characteristics,and maintain better fatigue characteristics,which can broaden the application range of the *** addition,we provide a theoretical and experimental framework for the research and applications in the field of metal ma

关键词： Entangled metallic wire material Composites materials Damping property Stiffness Fatigue characteristics

Inspires effective alternatives to backpropagation:predictive coding helps understand and build learning

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Neural Regeneration Research 2025年第11期20卷 3215-3216页

作者： Zhenghua Xu Miao Yu Yuhang song School of Health Sciences and Biomedical Engineering Hebei University of TechnologyTianjinChina Department of Computer Science University of OxfordOxfordUK

Artificial neural networks are capable of machine learning by simulating the hiera rchical structure of the human *** enable learning by brain and machine,it is essential to accurately identify and correct the prediction errors,referred to as credit assignment(Lillicrap et al.,2020).It is critical to develop artificial intelligence by understanding how the brain deals with credit assignment in neuroscience.

关键词： assignment learning enable

体外冲击波碎石后不同手术时机治疗输尿管结石的疗效比较

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腹腔镜外科杂志 2017年第7期22卷 497-500页

作者：谢留定白志功宋中建于民张彬驻马店市第一人民医院河南驻马店463000

目的:对比研究体外冲击波碎石后不同手术时机治疗输尿管结石的临床疗效。方法:选取2015年5月至2016年12月接受两次体外冲击波碎石后手术治疗的41例患者作为A组,另选取同期接受3次以上体外冲击波碎石后手术治疗的41例患者作为B组。对比... 详细信息

目的:对比研究体外冲击波碎石后不同手术时机治疗输尿管结石的临床疗效。方法:选取2015年5月至2016年12月接受两次体外冲击波碎石后手术治疗的41例患者作为A组,另选取同期接受3次以上体外冲击波碎石后手术治疗的41例患者作为B组。对比两组临床疗效、并发症发生情况、治疗前后BUN与Cr水平及生活质量。结果:A组治疗总有效率为95.12%,高于B组的68.29%(P<0.05)。A组术后感染、肾积水、梗阻发生率分别为36.59%、24.39%、19.51%,均低于B组的68.29%、56.10%、48.78%(P<0.05)。治疗后A组BUN、Cr水平均低于B组(P<0.05)。治疗后A组SF-36生活质量量表各项目评分均高于B组(P<0.05)。结论:患者接受体外冲击波碎石治疗2次及以上无法顺利排出结石时,应尽早接受手术治疗,以提高临床治疗效果,减少并发症的发生,有效促进肾功能的恢复,提高生活质量。

关键词：输尿管结石碎石术手术时机疗效比较研究

Neuronal regulated cell death in aging-related neurodegenerative diseases:key pathways and therapeutic potentials

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Neural Regeneration Research 2025年第8期20卷 2245-2263页

作者： Run song Shiyi Yin Jiannan Wu Junqiang Yan Department of Neurology The First Affiliated HospitalCollege of Clinical Medicine of Henan University of Science and TechnologyLuoyangHenan ProvinceChina Neuromolecular Biology Laboratory The First Affiliated HospitalCollege of Clinical Medicine of Henan University of Science and TechnologyLuoyangHenan ProvinceChina

Regulated cell death(such as apoptosis,necroptosis,pyroptosis,autophagy,cuproptosis,ferroptosis,disulfidptosis)involves complex signaling pathways and molecular effectors,and has been proven to be an important regulatory mechanism for regulating neuronal aging and ***,excessive activation of regulated cell death may lead to the progression of aging-related *** review summarizes recent advances in the understanding of seven forms of regulated cell death in age-related ***,the newly identified ferroptosis and cuproptosis have been implicated in the risk of cognitive impairment and neurodegenerative *** forms of cell death exacerbate disease progression by promoting inflammation,oxidative stress,and pathological protein *** review also provides an overview of key signaling pathways and crosstalk mechanisms among these regulated cell death forms,with a focus on ferroptosis,cuproptosis,and *** instance,FDX1 directly induces cuproptosis by regulating copper ion valency and dihydrolipoamide S-acetyltransferase aggregation,while copper mediates glutathione peroxidase 4 degradation,enhancing ferroptosis ***,inhibiting the Xc-transport system to prevent ferroptosis can increase disulfide formation and shift the NADP^(+)/NADPH ratio,transitioning ferroptosis to *** insights help to uncover the potential connections among these novel regulated cell death forms and differentiate them from traditional regulated cell death *** conclusion,identifying key targets and their crosstalk points among various regulated cell death pathways may aid in developing specific biomarkers to reverse the aging clock and treat age-related neurodegenerative conditions.

关键词： apoptosis autophagy cuproptosis disulfidptosis ferroptosis necroptosis neurodegenerative disease neurological aging diseases PANoptosis pyroptosis

Electrochemical conversion of methane to bridge the gap in the artificial carbon cycle

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Journal of Energy Chemistry 2025年第1期100卷 286-308页

作者： Yuhao Peng Yuefeng song Ihar Razanau Juanxiu Xiao Wei Xiao Di Hu Guoxiong Wang College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power Sources Wuhan University State Key Laboratory of Catalysis Dalian National Laboratory for Clean Energy iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Dalian Institute of Chemical Physics Chinese Academy of Sciences Laboratory of Physical-Chemical Technologies SSPA Scientific and Practical Materials Research Centre of NAS of Belarus State Key Laboratory of Marine Resources Utilization in South China Sea Collaborative Innovation Center of Marine Science and Technology School of Marine Science and Engineering Hainan University Department of Chemical and Environmental Engineering University of Nottingham Ningbo China

Methane, an abundant one-carbon（C1） resource, is extensively used in the industrial production of vital fuels and value-added chemicals. However, current industrial methane conversion technologies are energy-and carbon-intensive, mainly due to the high activation energy required to break the inert C–H bond, low selectivity, and problematic side reactions, including CO2emissions and coke deposition. Electrochemical conversion of methane（ECM） using intermittent renewable energy offers an attractive solution, due to its modular reactor design and operational flexibility across a broad spectrum of temperatures and pressures. This review emphasizes conversion pathways of methane in various reaction systems, highlighting the significance and advantages of ECM in facilitating a sustainable artificial carbon cycle. This work provides a comprehensive overview of conventional methane activation mechanisms and delineates the complete pathways of methane conversion in electrolysis contexts. Based on surface/interface chemistry, this work systematically analyzes proposed reaction pathways and corresponding strategies to enhance ECM efficiency towards various target products, including syngas, hydrocarbons, oxygenates, and advanced carbon materials. The discussion also encompasses opportunities and challenges for the ECM process, including insights into ECM pathways, rational electrocatalyst design, establishment of benchmarking protocols, electrolyte engineering, enhancement of CH4conversion rates, and minimization of CO2emission.

关键词： Methane Electrochemical conversion Reaction mechanism Catalyst design Electrode Electrocatalysis