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Transforaminal endoscopic excision of bi-segmental noncommunicating spinal extradural arachnoid cysts:A case report and literature review

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World Journal of Clinical Cases 2021年第31期9卷 9598-9606页

作者： zhi-he yun Jun Zhang Jiu-Ping Wu Tong Yu Qin-Yi Liu Department of Orthopaedics The Second Hospital of Jilin UniversityChangchun 130041Jilin ProvinceChina

BACKGROUND Spinal extradural arachnoid cysts(SEACs)are a rare cause of spinal cord ***,these cysts communicate with the intradural subarachnoid space through a small defect in the dural *** symptomatic SEACs,the standard treatment is to remove the cyst in total with a(hemi)laminectomy or *** present a rare case of bi-segmental non-communicating SEACs and describe our experience of using an endoscopic minimal access technique to remove bi-segmental non-communicating *** SUMMARY A 79-year-old female presented with pain related to bi-segmental SEACs at the T11-L1 *** underwent sequential transforaminal percutaneous endoscopic thoracic cystectomy of the *** her first procedure,spinal magnetic resonance imaging demonstrated complete excision of the cyst at the T12-L1 ***,the cyst at the T11-T12 segment was still ***,a second procedure was performed to remove this *** patient’s right-sided lumbar and abdominal pain improved significantly *** Japanese Orthopaedic Association score increased from 11 to 25,her visual analogue scale score was reduced from 8 to *** physical and mental component summary of the 36-item short-form health survey(SF-36)were 15.5 and 34.375 preoperatively,and had increased to 79.75 and 77.275 at the last follow-up visit,*** Bi-segmental non-communicating SEACs are extremely *** surgery is a safe,effective,and reliable method for treating these *** the event of bisegmental SEACs,it is important to identify whether both cysts are communicating before surgery,and if not,to remove both cysts separately during the index surgery to avoid re-operation.

关键词： Arachnoid cysts Cerebrospinal fluid Minimally invasive surgical procedures Thoracic surgery Case report

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Curcumin inhibits the growth and invasion of gastric cancer by regulating long noncoding RNA AC022424.2

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1437-1452页

作者： Bin-Sheng Wang Chen-Li Zhang Xiang Cui Qiang Li Lei Yang zhi-yun he Ze Yang Miao-Miao Zeng Nong Cao Department of General Surgery First Hospital of Lanzhou UniversityLanzhou 730000Gansu ProvinceChina School of Basic Medical Sciences Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Third Department of General Surgery First Hospital of Lanzhou UniversityLanzhou 730000Gansu ProvinceChina

BACKGROUND Gastric cancer,characterized by a multifactorial etiology and high heterogeneity,continues to confound researchers in terms of its ***,a natural anticancer agent,exhibits therapeutic promise in gastric *** effects include promoting cell apoptosis,curtailing tumor angiogenesis,and enhancing sensitivity to radiation and *** noncoding RNAs(lncRNAs)have garnered significant attention as biomarkers for early screening,diagnosis,treatment,and drug response because of their remarkable specificity and *** investigations have revealed an association between aberrant lncRNA expression and early diagnosis,clinical staging,metastasis,drug sensitivity,and prognosis in gastric cancer.A profound understanding of the intricate mechanisms through which lncRNAs influence gastric cancer develop-ment can provide novel insights for precision treatment and tailored management of patients with gastric *** study aimed to unravel the potential of curcumin in suppressing the malignant behavior of gastric cancer cells by upregu-lating specific lncRNAs and modulating gastric cancer onset and *** To identify lncRNAs associated with curcumin treatment and investigate the role of lncRNA AC022424.2 in the effects of curcumin on gastric cancer cell apoptosis,proliferation,and ***,these findings were validated in clinical *** The study employed CCK-8 assays to assess the impact of curcumin on gastric cancer cell proliferation,flow cytometry to investigate its effects on apoptosis,and scratch and Transwell assays to evaluate its influence on the migration and invasion of BGC-823 and MGC-803 *** blotting was used to gauge changes in the protein expression levels of CDK6,CDK4,Bax,Bcl-2,caspase-3,P65,and the PI3K/Akt/mTOR pathway in gastric cancer cell lines after curcumin *** expression of lncRNAs before and after curcumin treatment was assessed using lncRNA seq

关键词： Gastric cancer Curcumin Long noncoding RNA AC022424.2 Apoptosis Akt/PI3K pathway Lymph metastasis

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基于影像动画设计的知识表达模型

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计算机辅助设计与图形学学报 1998年第4期10卷 367-376页

作者：劳志强潘云鹤浙江大学CAD&CG国家重点实验室浙江大学人工智能研究所

首先对基于知识的动画技术进行了概述，然后就目前计算机动画技术中存在的问题，针对关节体提出了一个基于影像的知识表达模型，分别从图形对象的知识表达、运动知识表达和影像流知识表达等三个方面进行了描述，并给出了基于该模型设计... 详细信息

首先对基于知识的动画技术进行了概述，然后就目前计算机动画技术中存在的问题，针对关节体提出了一个基于影像的知识表达模型，分别从图形对象的知识表达、运动知识表达和影像流知识表达等三个方面进行了描述，并给出了基于该模型设计的动画系统的用户界面的框架，最后给出了结论．

关键词：计算机动画影像知识表达关节动画

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一个基于特征的图象变形算法

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计算机辅助设计与图形学学报 1998年第1期10卷 1-6页

作者：劳志强潘云鹤浙江大学CAD&CG国家重点实验室浙江大学人工智能研究所

首先对图象变形算法的研究作了一个简要的概述，然后结合我们目前所进行的智能动画系统的开发工作，提出了一个图象空间中基于特征的变形算法．在文中第二节较为详细地介绍了该算法中所用到的散乱点插值算法，最后给出了该变形算法的详... 详细信息

首先对图象变形算法的研究作了一个简要的概述，然后结合我们目前所进行的智能动画系统的开发工作，提出了一个图象空间中基于特征的变形算法．在文中第二节较为详细地介绍了该算法中所用到的散乱点插值算法，最后给出了该变形算法的详细描述．

关键词：图象变形算法图象处理智能动画系统

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Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy

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World Journal of Gastroenterology 2025年第1期31卷 110-125页

作者： Xin Zhou Dan Ma Yi-Xiang he Jing Jin Hong-Lian Wang yun-Feng Wang Fan Yang Jian-Qin Liu Jie Chen zhi Li Department of Spleen and Stomach Diseases the Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina The Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Digestive System Diseases of Luzhou City The Affiliated Traditional Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 20082China Research Center of Integrated Chinese and Western Medicine The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Integrated Traditional Chinese and Western Clinical Medicine North Sichuan Medical CollegeNanchong637100Sichuan ProvinceChina

BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after *** To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus *** Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential *** examinations occurred on days 7 and 21 *** vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was *** signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after *** treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal ***,the expression of fibrotic effector molecules was notably ***,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/*** vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen *** 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated *** KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.

关键词： Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis

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The detection, extraction and parameter estimation of extreme-mass-ratio inspirals with deep learning

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 86-96页

作者： Qianyun yun Wen-Biao Han Yi-Yang Guo he Wang Minghui Du Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences Shanghai Astronomical Observatory Chinese Academy of Sciences School of Physics and Astronomy Shanghai Jiao Tong University School of Astronomy and Space Science University of Chinese Academy of Sciences Taiji Laboratory for Gravitational Wave Universe (Beijing/Hangzhou) University of Chinese Academy of Sciences Lanzhou Center for Theoretical Physics Key Laboratory of Theoretical Physics of Gansu Province Key Laboratory of Quantum Theory and Applications of MoE Lanzhou University Institute of Theoretical Physics & Research Center of Gravitation Lanzhou University International Centre for Theoretical Physics Asia-Pacific (ICTP-AP) University of Chinese Academy of Sciences (UCAS) Center for Gravitational Wave Experiment National Microgravity Laboratory Institute of Mechanics Chinese Academy of Sciences

One of the primary goals of space-borne gravitational wave detectors is to detect and analyze extreme-mass-ratio inspirals(EMRIs). This task is particularly challenging because EMRI signals are complex, lengthy, and faint. In this work, we introduce a2-layer convolutional neural network(CNN) approach to detect EMRI signals for space-borne detectors, achieving a true positive rate(TPR) of 96.9% at a 1% false positive rate(FPR) for signal-to-noise ratio(SNR) from 50 to 100. Especially, the key intrinsic parameters of EMRIs such as the mass, spin of the supermassive black hole(SMBH) and the initial eccentricity of the orbit can also be inferred directly by employing a neural network. The mass and spin of the SMBH can be determined at 99% and 92% respectively. This will greatly reduce the parameter spaces and computing cost for the following Bayesian parameter *** model also has a low dependency on the accuracy of the waveform model. This study underscores the potential of deep learning methods in EMRI data analysis, enabling the rapid detection of EMRI signals and efficient parameter estimation.

关键词： gravitational wave EMRIs deep-learing

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Recent progress in constructing fluorinated solid-electrolyte interphases for stable lithium metal anodes

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 270-291页

作者： Di Zhang Pengfei Lv Wei Qin Xin he Yuanhua he Civil Aircraft Fire Science and Safety Engineering Key Laboratory of Sichuan Province College of Civil Aviation Safety EngineeringCivil Aviation Flight University of ChinaGuanghan 618307China School of Chemical Engineering Sichuan UniversityChengdu 610065China

Lithium metal batteries(LMBs)are emerging as a promising energy storage solution owing to their high energy density and specific ***,the non-uniform plating of lithium and the potential rupture of the solid-electrolyte interphase(SEI)during extended cycling use may result in dendrite growth,which can penetrate the separator and pose significant short-circuit *** a stable SEI is essential for the long-term operation of the ***-rich SEI has garnered significant attention for its ability to effectively passivate electrodes,regulate lithium deposition,and inhibit electrolyte *** the structural components and preparation methods of existing fluorinated SEI is crucial for optimizing lithium metal anode *** paper reviews the research on optimizing LiF passivation interfaces to protect lithium metal *** focuses on four types of compositions in fluorinated SEI that work synergistically to enhance SEI *** instance,combining compounds with LiF can further enhance the mechanical strength and ionic conductivity of the *** metals with LiF significantly improves electrochemical performance at the SEI/anode interface,with a necessary focus on reducing electron tunneling ***,incorporating polymers with LiF offers balanced improvements in interfacial toughness and ionic conductivity,though maintaining structural stability over long cycles remains a critical area for future *** alloys combined with LiF increase surface energy and lithium affinity,challenges such as dendrite growth and volume expansion *** summary,this paper emphasizes the crucial role of interfacial structures in LMBs and offers comprehensive guidance for future design and development efforts in battery technology.

关键词： LiF lithium metal anodes solid-electrolyte interphase interface cycling stability

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Record-breaking bifunctional oxygen electrocatalyst accomplished by a data-driven approach for zinc-air batteries

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Journal of Energy Chemistry 2025年第1期100卷 144-145页

作者： Deviprasath Chinnadurai zhi Wei Seh Institute of Materials Research and Engineering (IMRE) Agency for Science Technology and Research (A*STAR)

Rechargeable zinc-air batteries(ZABs) have recently drawn great attention in energy research due to their high theoretical capacity,low costs, and inherently safe nature [1–3]. However, the sluggish cathode reactions necessitate the development of bifunctional oxygen electrocatalysts with lower ΔE indicator values. The ΔE indicator is commonly employed to quantitatively evaluate the electrocatalytic activity of a bifunctional oxygen electrocatalyst,representing the overall overpotential from oxygen reduction reaction(ORR) to oxygen evolution reaction(OER).

关键词： Data-driven approach Bifunctional oxygen electrocatalyst Record breaking performance Zinc-air batteries

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四川盆地高石梯构造灯影组四段溶蚀孔洞型储层类型及组合模式

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天然气地球科学 2017年第8期28卷 1191-1198页

作者：张林万玉金杨洪志苏云河张满郎中国石油勘探开发研究院河北廊坊065007 中国石油西南油气田分公司勘探开发研究院四川成都610000

震旦纪高石梯构造位于四川盆地绵竹—长宁克拉通内裂陷东侧的台地边缘带,发育藻灰泥丘、砂屑滩及云坪,同时受震旦纪末期桐湾Ⅱ幕构造运动的抬升暴露剥蚀并形成岩溶风化壳。灯四段为溶蚀孔洞型白云岩储层,主要储集空间有溶洞、溶孔及晶... 详细信息

震旦纪高石梯构造位于四川盆地绵竹—长宁克拉通内裂陷东侧的台地边缘带,发育藻灰泥丘、砂屑滩及云坪,同时受震旦纪末期桐湾Ⅱ幕构造运动的抬升暴露剥蚀并形成岩溶风化壳。灯四段为溶蚀孔洞型白云岩储层,主要储集空间有溶洞、溶孔及晶间孔。在岩心、成像测井和常规测井对溶蚀孔洞型储层的定量判识基础上,划分洞穴型、孔洞型、孔隙型、裂缝—孔洞型、裂缝—孔隙型和裂缝型6类储集空间。在纵向上,根据储集空间类型及其组合特征提出洞穴—孔洞型、裂缝—孔洞型、孔洞型、裂缝—孔隙型、裂缝型5类储层组合模式。其中洞穴—孔洞型、裂缝—孔洞型为高产长期稳产型,是最好的储层组合类型;孔洞型为中产长期稳产型;裂缝—孔隙型和裂缝型则为高产短期稳产型。

关键词：岩溶储层组合模式灯影组四段高石梯四川盆地

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Sex-dependent alterations in extracellular vesicles linking chronic spinal cord injury to brain neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第2期20卷 483-484页

作者： yun Li Junfang Wu Department of Anesthesiology&Shock Trauma and Anesthesiology Research(STAR)CenterUniversity of Maryland School of MedicineBaltimoreMDUSA

Traumatic spinal cord injury(SCI)is a devastating exogenous injury with long-lasting consequences and a leading cause of death and disability *** in assistive technology,rehabilitative interventions,and the ability to identify and intervene in secondary conditions have significantly increased the long-term survival rate of SCI patients,with some people even living well into their seventh or eighth *** survival changes have led neurotrauma researchers to examine how SCI interacts with brain *** health and epidemiological data showed that patients with long-term SCI can have a lower life expectancy and quality of life,along with a higher risk of comorbidities and complications.

关键词： alterations inflammation injury

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