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Evolution and control of nonmetallic inclusions in FeSiB alloy

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Journal of Iron and Steel Research International 2020年第5期27卷 588-597页

作者： Bai-song Li wen-zhi chen Yu-lin Zhao Pei Zhao Central Iron and Steel Research Institute Beijing 100081China Advanced Technology and Materials Co. Ltd.China Iron and Steel Research Institute GroupBeijing 100081China

Inclusions have a great infuence on the quality of FeSiB amorphous *** evolution behavior of inclusions was *** results show that the spherical and elliptical inclusions,consisting of Al2O3 and SiO2,mainly come from industrial pure *** inclusions of 20-30μm in pure iron were removed by foatation during the smelting process,and spherical inclusions of 1-3μm combined with deoxidized products in FeSiB melt form Al2O3·SiO2 and CaO·Al2O3·SiO2 *** inclusions accumulated on the inner wall of the nozzle during the spraying process,and others fowed out of the nozzle and remained in FeSiB amorphous *** controlling the total oxygen content in industrial pure iron to 31×10^-6,clogging on the inner wall of the nozzle can be reduced and the free surface smoothness of the amorphous ribbon can be improved.

关键词： FeSiB alloy Nonmetallic inclusion Thermodynamics Nozzle clogging

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第6期9卷 807-815页

作者： Ren-fang WANG wen-zhi chen San-yuan ZHANG Yin ZHANG Xiu-zi YE School of Computer Science and Technology Zhejiang University Hangzhou 310027 China Faculty of Computer Science and Information Technology Zhejiang Wanli University Ningbo 315100 China

A non-local denoising (NLD) algorithm for point-sampled surfaces (PSSs) is presented based on similarities, including geometry intensity and features of sample points. By using the trilateral filtering operator, the differential signal of each sample point is determined and called "geometry intensity". Based on covariance analysis, a regular grid of geometry intensity of a sample point is constructed, and the geometry-intensity similarity of two points is measured according to their grids. Based on mean shift clustering, the PSSs are clustered in terms of the local geometry-features similarity. The smoothed geometry intensity, i.e., offset distance, of the sample point is estimated according to the two similarities. Using the resulting intensity, the noise component from PSSs is finally removed by adjusting the position of each sample point along its own normal direction. Ex- perimental results demonstrate that the algorithm is robust and can produce a more accurate denoising result while having better feature preservation.

关键词： Point-sampled surfaces (PSSs) Similarity Geometry intensity Geometry feature Non-local filtering

Cell behaviors on surface of pure tantalum with nano-dimpled structure

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Rare Metals 2019年第6期38卷 543-551页

作者： Jun-Wei Ma Rui Zan wen-zhi chen Jia-Hua Ni Xiao-Nong Zhang State Key Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China California Nanosystems Institute University of CaliforniaLos AngelesCaliforniaCA 90095USA

Tantalum exhibits excellent biocompatibility and good chemical stability, which has been employed in dental and orthopedic *** local microenvironment of the surface of implants influence determines the surrounding cell *** this work, nano-dimpled structure on the surface of pure tantalum was fabricated by electrochemical *** surface morphology of the nano-dimpled structure was observed, and the dimensions of the nano-dimpled structure were measured by scanning electron microscopy(SEM).The surface roughness of the sample with nano-dimpled structure was measured by atomic force microscopy(AFM).The results show that the diameter of nano-dimpled ranges from 40 to 180 nm, and the higher the applied voltage, the larger the ***, nano-dimpled structure has good *** vitro results show that nano-dimpled structure can promote the adhesion and proliferation of mouse cranial anterior bone(MC-3T3-E1) *** filopodia of MC-3T3-E1 cells can be fully extended on this nano-dimpled *** the surface of the nano-dimpled structure with a dimple size of 40 nm, the cells have the longest aspect *** small dimple size of the nanodimpled structure is beneficial to cell proliferation and osteogenic differentiation.

关键词： Tantalum Nano-dimpled structure Cell behaviors Anodization

A candidate protective factor in amyotrophic lateral sclerosis:heterogenous nuclear ribonucleoprotein G

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Neural Regeneration Research 2023年第7期18卷 1527-1534页

作者： Fang Yang wen-zhi chen Shi-Shi Jiang Xiao-Hua Wang Ren-Shi Xu Department of Neurology Jiangxi Provincial People’s HospitalThe Clinical College of Nanchang Medical CollegeThe First Affiliated Hospital of Nanchang Medical CollegeNanchangJiangxi ProvinceChina Department of Geriatrics and General Practice/General Family Medicine Jiangxi Provincial People’s HospitalThe Clinical College of Nanchang Medical CollegeThe First Affiliated Hospital of Nanchang Medical CollegeNanchangJiangxi ProvinceChina

Heterogenous nuclear ribonucleoprotein G is down-regulated in the spinal cord of the Tg(SOD1*G93A)1Gur(TG)amyotrophic lateral sclerosis mouse ***,most studies have only examined heterogenous nuclear ribonucleoprotein G expression in the amyotrophic lateral sclerosis model and heterogenous nuclear ribonucleoprotein G effects in amyotrophic lateral sclerosis pathogenesis such as in apoptosis are *** this study,we studied the potential mechanism of heterogenous nuclear ribonucleoprotein G in neuronal death in the spinal cord of TG and wild-type mice and examined the mechanism by which heterogenous nuclear ribonucleoprotein G induces *** nuclear ribonucleoprotein G in spinal cord was analyzed using immunohistochemistry and western blotting,and cell proliferation and proteins(TAR DNA binding protein 43,superoxide dismutase 1,and Bax)were detected by the Cell Counting Kit-8 and western blot analysis in heterogenous nuclear ribonucleoprotein G siRNA-transfected PC12 *** analyzed heterogenous nuclear ribonucleoprotein G distribution in spinal cord in the amyotrophic lateral sclerosis model at various time points and the expressions of apoptosis and proliferation-related *** nuclear ribonucleoprotein G was mainly localized in *** lateral sclerosis mice were examined at three stages:preonset(60-70 days),onset(90-100 days)and progression(120-130 days).The number of heterogenous nuclear ribonucleoprotein G-positive cells was significantly higher in the anterior horn of the lumbar spinal cord segment of TG mice at the preonset stage than that of control group but lower than that of the control group at the onset *** number of heterogenous nuclear ribonucleoprotein G-positive cells in both central canal and surrounding gray matter of the whole spinal cord of TG mice at the onset stage was significantly lower than that in the control group,whereas that of the lumbar spinal cord segment of TG mice was

关键词： amyotrophic lateral sclerosis Bax heterogenous nuclear ribonucleoprotein G heterogenous nuclear ribonucleoprotein G-siRNA neuron death superoxide dismutase 1 TAR DNA binding protein 43 TG(SOD1*G93A)1Gur mice

Phosphoinositide-3-kinase regulatory subunit 4 participates in the occurrence and development of amyotrophic lateral sclerosis by regulating autophagy

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Neural Regeneration Research 2022年第7期17卷 1609-1616页

作者： Yue Liu Cai-Hui Wei cheng Li wen-zhi chen Yu Zhu Ren-Shi Xu Department of Neurology First Affiliated Hospital of Nanchang Medical CollegeJiangxi Provincial People’s HospitalAffiliated People’s Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina

The development of amyotrophic lateral sclerosis(ALS)may be related to the abnormal alterations of multiple *** previous study revealed that the expression of phosphoinositide-3-kinase regulatory subunit 4(PIK3R4)was decreased in ***,the role of PIK3R4 in ALS pathogenesis remains *** study was the first to find that transfection of PC12 cells with small interfering RNA against the PIK3R4 gene significantly decreased the expression levels of PIK3R4 and the autophagy-related proteins p62 and ***,in vivo experiments revealed that the PIK3R4 protein was extensively expressed in the anterior horn,posterior horn,central canal,and areas surrounding the central canal in cervical,thoracic,and lumbar segments of the spinal cord in adult ***3R4 protein was mainly expressed in the neurons within the spinal lumbar ***3R4 and p62 expression levels were significantly decreased at both the pre-onset and onset stages of ALS disease in Tg(SOD1*G93A)1 Gur mice compared with control mice,but these proteins were markedly increased at the progression ***3 protein expression did not change during progression of *** findings suggest that PIK3R4 likely participates in the prevention of ALS *** study was approved by the Ethics Committee for Animal Care and Use of Jiangxi Provincial People’s Hospital,Affiliated People’s Hospital of Nanchang University(approval No.2020025)on March 26,2020.

关键词： amyotrophic lateral sclerosis autophagy LC3 p62 PC12 cell phosphoinositide-3-kinase regulatory subunit 4 spinal cord Tg(SOD1*G93A)1Gur mice

5-Hydroxytryptamine:a potential therapeutic target in amyotrophic lateral sclerosis

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Neural Regeneration Research 2023年第9期18卷 2047-2055页

作者： Shi-Shi Jiang Meng-Ni Gong Wei Rao wen Chai wen-zhi chen Xiong Zhang Hong-Bing Nie Ren-Shi Xu Medical College of Nanchang University Department of NeurologyJiangxi Provincial People’s HospitalThe First Affiliated Hospital of Nanchang Medical CollegeClinical College of Nanchang Medical CollegeNanchangJiangxi ProvinceChina Department of Neurology The First Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Department of Neurology Maoming People’s HospitalMaomingGuangdong ProvinceChina

Previous studies have indicated that the pathogenesis of amyotrophic lateral sclerosis(ALS) is closely linked to 5-hydroxytryptamine(5-HT).To investigate this further,we administered 5-HT receptor antagonists to SOD1*G93A transgenic(ALS mouse model) and wide-type *** involved intraperitoneal injections of either granisetron,piboserod,or ritanserin,which inhibit the 5-HT3,5-HT4,and 5-HT2 receptors,*** transgenic mice were found to have fewer5-HT-positive cells in the spinal cord compared with wide-type *** found that the administration of granisetron reduced the body weight of the transgenic mice,while piboserod and ritanserin worsened the motor functioning,as assessed using a hanging wire ***,none of the 5-HT receptor antagonists affected the disease *** analyzed the distribution and/or expression of TAR DNA binding protein 43(TDP-43) and superoxide dismutase 1 G93A(SOD1-G93A),which fo rm abnormal aggregates in *** found that the expression of these proteins increased following the administration of all three 5-HT receptor *** addition,the disease-related mislocalization of TD P-43 to the cytoplasm increased markedly for all three *** ce rtain anatomical regions,the 5-HT receptor antagonists also led to a marked increase in the number of astrocytes and microglia and a decrease in the number of *** results indicate that 5-HT deficiency may play a role in the pathogenesis of amyotrophic lateral sclerosis by inducing the abnormal expression and/or distribution of TDP-43 and SOD1-G93A and by activating glial cells.5-HT co uld therefore be a potential therapeutic target for amyotrophic lateral sclerosis.

关键词： 5-hydroxytryptamine amyotrophic lateral sclerosis astrocytes granisetron microglia neuron piboserod ritanserin SOD1-G93A TAR DNA-binding protein 43

Recent research situation in tin dioxide nanomaterials： synthesis, microstructures, and properties

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Frontiers of Materials Science 2013年第3期7卷 203-226页

作者： zhi-wen chen Chan-Hung SHEK C. M. Lawrence WU Joseph K. L. LAI Shanghai Applied Radiation Institute School of Environmental and Chemical Engineering Shanghai University Shanghai 200444 China Department of Physics and Materials Science City University of Hong Kong Tat Chee Avenue Kowloon Tong Hong Kong China

This review article summarizes the new research in solid-state physical chemistry understanding of the microstructure characteristics of semiconductor tin oxide thin films made in the last years in our group. The work mainly focuses on the fabrication technology of semiconductor tin oxides thin films by using pulsed laser deposition （PLD） as well as the application of this technology on new micro- and nanostructured materials. It is an interdisciplinary work that integrates the areas of physics, chemistry and materials science.

关键词： tin dioxide thin film synthesis microstructure nanostructure property

Magnetic emission intensity enhancement for amorphous alloys by constructing a multi-phase structure withα-Fe nanocrystals

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Nano Research 2024年第7期17卷 6630-6637页

作者： Ke Liu zhi Qin Jie Shen zhi cheng Shiyue You Liang Ma Jing Zhou wen chen State Key Laboratory of Advanced Technology for Materials Synthesis and Processing School of Materials Science and EngineeringWuhan University of TechnologyWuhan 430070China Sanya Science and Education Innovation Park Wuhan University of TechnologySanya 572024China Hubei Longzhong Laboratory Wuhan University of Technology Xiangyang Demonstration ZoneXiangyang 441000China

The perturbation in the magnetic field generated by the rotation or oscillation of magnetic domains in magnetic materials can emit low-frequency electromagnetic waves,which are expected to be used in low-frequency ***,the magnetic emission intensity,defined by the perturbation ability,of current commercially applied amorphous alloys,such as Metglas,cannot meet the application requirements for low-frequency antennas due to the domain motion energy ***,a multi-phase Metglas amorphous alloy was constructed by incorporatingα-Fe nanocrystals using rapid annealing to manipulate the domain *** was found that 3.89 times higher magnetic emission intensity is obtained compared to the pristine due to the synergism of the deformation and displacement ***,the low-frequency magnetic emission performance verification was carried out by preparing magnetoelectric composites as the antenna vibrator by assembling the alloy and macro piezoelectric fiber composites(MFC).Enhancements of magnetic emission intensity are found at 93.3%and 49.2%at the first and second harmonic frequencies compared with the unmodified alloy ***,the approach leads to the development of high-performance communication with a novel standard for evaluation.

关键词： multi-phase amorphous alloys magnetic emission intensity enhancing mechanism magnetic domain pinning theory Jiles-Atherton model analysis

Cotton genome: challenge into the polyploidy

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Science Bulletin 2017年第24期62卷 1622-1623页

作者： zhi-wen chen Jun-Feng Cao Xiu-Fang Zhang Xiao-Xia Shangguan Ying-Bo Mao Ling-Jian Wang Xiao-Ya chen National Key Laboratory of Plant Molecular Genetics and National Center for Plant Gene Research Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Plant Science Research Center Shanghai Chenshan Botanical Garden Shanghai Key Laboratory of Plant Functional Genomics and Resources

Cottons are the most important fiber crops in the *** cotton genus Gossypium has 52 species,including seven allotetraploid species and 45 *** species were domesticated and remain as crops under cultivation today:the New World allopolyploid species *** and ***(2n=52),and the Old World diploid species *** and ***(2n=26).The primary cultivated species is Upland cotton(*** L.),which accounts for more than 90%of global cotton fiber production.

关键词： Cotton genome challenge into the polyploidy