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Effect of integration of mechanical ball milling and flue gas desulfurization gypsum on dealkalization of bauxite residue

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Transactions of Nonferrous Metals Society of China 2024年第8期34卷 2702-2713页

作者： Feng ZHU Xu-yao GUO Jun JIANG Kai-bin CHEN Xuan-zhi ZHU Dan-dan DENG Yu-jun WU Yu-wei HUANG sheng-guo XUE School of Metallurgy and Environment Central South UniversityChangsha 410083China Zhengzhou Non-ferrous Metals Research Institute Co. Ltd.of CHALCOZhengzhou 450041China College of Environment and Resources Xiangtan UniversityXiangtan 411105China School of Resources and Safety Engineering Central South UniversityChangsha 410083China

The synergistic impact of mechanical ball milling and flue gas desulfurization(FGD)gypsum on the dealkalization of bauxite residue was investigated through integrated analyses of solution chemistry,mineralogy,and *** results showed a significant decrease in Na_(2)O content(>30 wt.%)of FGD gypsum-treated bauxite residue after 30 min of mechanical ball *** ball milling resulted in differentiation of the elemental distribution,modification of the minerals in crystalline structure,and promotion in the dissolution of alkaline minerals,thus enhancing the acid neutralization capacity of bauxite residue.5 wt.%FGD gypsum combined with 30 min mechanical ball milling was optimal for the dealkalization of bauxite residue.

关键词： bauxite residue alkalinity regulation flue gas desulfurization gypsum mechanical activation soil formation of bauxite residue

Artificial intelligence-driven radiomics study in cancer:the role of feature engineering and modeling

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Military Medical Research 2024年第1期11卷 115-147页

作者： Yuan-Peng Zhang Xin-Yun Zhang Yu-Ting Cheng Bing Li Xin-zhi Teng Jiang Zhang Saikit Lam Ta Zhou Zong-Rui Ma Jia-Bao sheng Victor CWTam Shara WYLee Hong Ge Jing Cai Department of Medical Informatics Nantong UniversityNantong 226001JiangsuChina Department of Health Technology and Informatics the Hong Kong Polytechnic UniversityHong Kong 999077China The Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518000GuangdongChina Department of Radiation Oncology the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer HospitalZhengzhou 450008China

Modern medicine is reliant on various medical imaging technologies for non-invasively observing patients’***,the interpretation of medical images can be highly subjective and dependent on the expertise of ***,some potentially useful quantitative information in medical images,especially that which is not visible to the naked eye,is often ignored during clinical *** contrast,radiomics performs high-throughput feature extraction from medical images,which enables quantitative analysis of medical images and prediction of various clinical *** have reported that radiomics exhibits promising performance in diagnosis and predicting treatment responses and prognosis,demonstrating its potential to be a non-invasive auxiliary tool for personalized ***,radiomics remains in a developmental phase as numerous technical challenges have yet to be solved,especially in feature engineering and statistical *** this review,we introduce the current utility of radiomics by summarizing research on its application in the diagnosis,prognosis,and prediction of treatment responses in patients with *** focus on machine learning approaches,for feature extraction and selection during feature engineering and for imbalanced datasets and multi-modality fusion during statistical ***,we introduce the stability,reproducibility,and interpretability of features,and the generalizability and interpretability of ***,we offer possible solutions to current challenges in radiomics research.

关键词： Artificial intelligence Radiomics Feature extraction Feature selection Modeling Interpretability Multimodalities Head and neck cancer

农村金融理论新范式:基本原理、实践模式与政策意蕴

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经济学家 2024年第9期 119-128页

作者：陈小知米运生广东金融学院华南创新金融研究院华南农业大学经济管理学院

农村金融领域不完全竞争范式已经脱离了发展中国家之现实。地缘、业缘、亲缘的巨大变化,既带来了农户信用信息的丰富性、空间与行业分布的分散性,也增添了信用评估的技术复杂性。在信息收集与评估方面,以银行为代表的正规金融机构已在... 详细信息

农村金融领域不完全竞争范式已经脱离了发展中国家之现实。地缘、业缘、亲缘的巨大变化,既带来了农户信用信息的丰富性、空间与行业分布的分散性,也增添了信用评估的技术复杂性。在信息收集与评估方面,以银行为代表的正规金融机构已在总体上居优,但“大国小农”的国情农情使得民间中介在还款意愿信息方面将在长期内拥有比较优势。本文将这种新的范式概念化为信息比较优势,并以中国为案例,系统讨论信息比较优势的基本原理、实践模式与政策意蕴。信息比较优势范式的提出,既是对传统范式的迭代,也标志着农村金融领域中国学派的形成。在新的理论范式指引下,中国特色农村金融现代化发展道路也将行稳致远。

关键词：农村金融理论范式信息比较优势实践模式政策取向

基于轻量级MobileNet-SSD模型的人流量检测

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计算机应用与软件 2024年第1期41卷 89-96,145页

作者：张智盛健武汉科技大学计算机科学与技术学院湖北武汉430065 智能信息处理与实时工业系统湖北省重点实验室湖北武汉430065 武汉科技大学大数据科学与工程研究院湖北武汉430065

利用深度神经网络模型识别行人目标并检测具有十分高的价值。现实高密度行人检测场景中由于硬件基础以及网络性能消耗等问题的影响,常常需要选取处理速度高、硬件条件要求低的网络且同时兼顾视频监控的连续特性,因此选取了轻量级MobileN... 详细信息

利用深度神经网络模型识别行人目标并检测具有十分高的价值。现实高密度行人检测场景中由于硬件基础以及网络性能消耗等问题的影响,常常需要选取处理速度高、硬件条件要求低的网络且同时兼顾视频监控的连续特性,因此选取了轻量级MobileNet-SSD网络来高效处理人头目标并引入帧间差分的方式,来有效对人头的椭圆特征目标进行跟踪;结合相关数理方法实现行人跨线计数的高性能人流量检测解决方案。在不同数据集上同现今一流的检测模型作比较,该方法皆表现出优良的检测性能。

关键词： MobileNet-SSD 帧间差分跨线计数轻量级网络

Efficacy and safety of Qingfei Huatan formula in the treatment of acute exacerbation of chronic obstructive pulmonary disease: A multi-centre,randomised, double-blind, placebo-controlled trial

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Journal of Integrative Medicine 2024年第05期 561-569页

作者： Hui-zhi Zhu Cheng-yi Li Liang-ji Liu Jia-bing Tong zhi-hui Lan Shu-guang Tian Qiao Li Xiang-li Tong Ji-feng Wu Zhen-gang Zhu Su-yun Li Jian-sheng Li Department of Respiratory Medicine the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine Graduate School Anhui University of Traditional Chinese Medicine Department of Respiratory Medicine Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine Department of Respiratory Diseases the First Affiliated Hospital of Henan University of Traditional Chinese Medicine Department of Pulmonary Diseases Taihe Hospital of Traditional Chinese Medicine Affiliated to Anhui University of Traditional Chinese Medicine Department of Respiratory and Critical Care Medicine Jiangxi Province Hospital of Integrated Chinese and Western Medicine Department of Respiratory Medicine the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment and Chinese Medicine Development of Henan Province

Background: Chronic obstructive pulmonary disease(COPD), a common respiratory disease, can be effectively treated by traditional Chinese medicine(TCM). Qingfei Huatan, a TCM formula, has been reported to effectively alleviate the clinical symptoms of COPD patients. However, there is a lack of multi-centre,randomised, double-blind, controlled clinical trials documenting the clinical efficacy and safety of this formula in the treatment of acute exacerbation of COPD(AECOPD).Objective: This study evaluated the efficacy and safety of Qingfei Huatan formula in the treatment of AECOPD, thereby providing high-quality clinical ***, setting, participants and interventions: A total of 276 patients with AECOPD were included in this multi-centre, randomised, double-blind, placebo-controlled trial and were randomised into treatment and control groups at a ratio of 1:1. Patients in the treatment and control groups took Qingfei Huatan granules or simulated Qingfei Huatan granules twice a day, for 14 days, in addition to Western medicine treatment. All patients were followed up for 3 *** outcome measures: The primary outcome was time taken to symptom stabilisation. The secondary outcomes included duration of antibiotic use, clinical symptom and sign score, TCM syndrome score, dyspnoea score, and quality of life(QOL) score. Meanwhile, the safety of the formula was assessed through routine urine and stool tests, electrocardiograms, liver and kidney function tests, and the observation of adverse events throughout the ***: The time taken for effective stabilisation(P < 0.05) and obvious stabilisation(P < 0.01), and the duration of antibiotic use(P < 0.05) were significantly shorter in the treatment group than in the control group. On days 6, 9, 12 and 14 of treatment, clinical symptom and sign score decreased in both groups,particularly in the treatment group(P < 0.01). On days 9, 12 and 14 of treatment, the TCM syndrome scores of both groups were reduced(P

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Genomic data and ecological niche modeling reveal an unusually slow rate of molecular evolution in the Cretaceous Eupteleaceae

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Science China(Life Sciences) 2024年第4期67卷 803-816页

作者： Kun-Li Xiang sheng-Dan Wu Lian Lian Wen-Chuang He Dan Peng Huan-Wen Peng Xiao-Ni Zhang Hong-Lei Li Jia-Yu Xue Hong-Yan Shan Gui-Xia Xu Yang Liu zhi-Qiang Wu Wei Wang State Key Laboratory of Plant Diversity and Specialty Crops Institute of BotanyChinese Academy of SciencesBeijing 100093China Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureKey Laboratory of Synthetic BiologyLaboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China China National Botanical Garden Beijing 100093China State Key Laboratory of Grassland Agro-Ecosystems and College of Ecology Lanzhou UniversityLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China College of Landscape Architecture and Life Science/Institute of Special Plants Chongqing University of Arts and SciencesChongqing 402160China College of Horticulture Academy for Advanced Interdisciplinary StudiesNanjing Agricultural UniversityNanjing 210095China Fairylake Botanical Garden Shenzhen&Chinese Academy of SciencesShenzhen 518004China

Living fossils are evidence of long-term sustained ecological ***,whether living fossils have little molecular changes remains poorly known,particularly in ***,we have introduced a novel method that integrates phylogenomic,comparative genomic,and ecological niche modeling analyses to investigate the rate of molecular evolution of Eupteleaceae,a Cretaceous relict angiosperm family endemic to East *** assembled a high-quality chromosome-level nuclear genome,and the chloroplast and mitochondrial genomes of a member of Eupteleaceae(Euptelea pleiosperma).Our results show that Eupteleaceae is most basal in Ranunculales,the earliest-diverging order in eudicots,and shares an ancient whole-genome duplication event with the other *** document that Eupteleaceae has the slowest rate of molecular changes in the observed *** unusually low rate of molecular evolution of Eupteleaceae across all three independent inherited genomes and genes within each of the three genomes is in association with its conserved genome architecture,ancestral woody habit,and conserved niche *** findings reveal the evolution and adaptation of living fossil plants through large-scale environmental change and also provide new insights into early eudicot diversification.

关键词： conservation genomics eudicots evolutionary rates niche conservatism phylogenomics

Vasculogenic mimicry:a pivotal mechanism contributing to drug resistance in antiangiogenic therapy

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Oncology and Translational Medicine 2024年第3期10卷 119-125页

作者： Shu-Min dang Dan Yang zhi-Yi Wang Xiang-Ming Ding Xiu-Ling Li De-Yu Li Dong-Xiao Li Department of Gastroenterology People’s Hospital of Zhengzhou UniversityHenan Provincial People’s HospitalZhengzhouHenanChina Henan Key Medical Laboratory for Molecular Immunology of Digestive Diseases Henan Provincial People’s HospitalZhengzhouHenanChina Department of Hepatobiliary Surgery People’s Hospital of Zhengzhou UniversityHenan Provincial People’s HospitalZhengzhouHenanChina Henan Provincial Key Medical Laboratory for Hepatobiliary and Pancreatic Diseases Henan Provincial People’s HospitalZhengzhouHenanChina

The growth of solid tumors relies on establishing a robust blood supply,with angiogenesis playing a key role in this intricate *** on this understanding,therapeutic strategies targeting tumor angiogenesis have been ***,the clinical effectiveness of antiangiogenic therapy(AAT)in treating tumors has not lived up to *** recent years,vasculogenic mimicry(VM)has attracted increasing attention from the academic community as a longstanding but often overlooked mechanism of nonangiogenic tumor *** the tumor microenvironment,neoplastic cells can autonomously form vessel-like structures,creating a blood supply that does not rely on endothelial *** phenomenon,known as VM,is a critical marker of aggressive tumors and may play a significant role in conferring resistance to *** this review,we thoroughly examine the evidence,clinical characteristics,and mechanisms of VM across various tumor types and explore its potential role and importance in resistance to AAT and the development of new antitumor therapies.

关键词： Vasculogenic mimicry Antiangiogenic therapy Angiogenesis Tumor microenvironment Immunotherapy

Direct measurement of the break-out ^(19)F(p,γ)^(20)Ne reaction in the China Jinping underground laboratory(CJPL)

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Nuclear Science and Techniques 2024年第8期35卷 142-152页

作者： Yin‑Ji Chen Hao Zhang Li‑Yong Zhang Jian‑Jun He Richard James deBoer Michael Wiescher Alexander Heger David Kahl Jun Su Daniel Odell Xin‑Yue Li Jian‑Guo Wang Long Zhang Fu‑Qiang Cao zhi‑Cheng Zhang Xin‑zhi Jiang Luo‑Huan Wang Zi‑Ming Li Lu‑Yang Song Liang‑Ting Sun Qi Wu Jia‑Qing Li Bao‑Qun Cui Li‑Hua Chen Rui‑Gang Ma Er‑Tao Li Gang Lian Yao‑De sheng zhi‑Hong Li Bing Guo Wei‑Ping Liu Key Laboratory of Beam Technology of the Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China Department of Physics and Astronomy The Joint Institute for Nuclear AstrophysicsUniversity of Notre DameNotre DameIN 46556USA School of Physics and Astronomy Monash UniversityClaytonVIC 3800Australia Facility for Rare Isotope Beams Michigan State UniversityEast LansingMI 48824USA Institute of Nuclear and Particle Physics and Department of Physics and Astronomy Ohio UniversityAthensOH 45701USA Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China China Institute of Atomic Energy Beijing 102413China College of Physics and Optoelectronic Engineering Shenzhen UniversityShenzhen 518060China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China College of Science Southern University of Science and TechnologyShenzhen 518055China Institute of Radiation Technology Beijing Academy of Science and TechnologyBeijing 100875China Key Laboratory of Nuclear Physics and Ion‑Beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China School of Mathematics and Physics Handan UniversityHandan 056005China

Calcium production and the stellar evolution of first-generation stars remain fascinating mysteries in *** one possible nucleosynthesis scenario,break-out from the hot carbon–nitrogen–oxygen(HCNO)cycle was thought to be the source of the calcium observed in these oldest ***,according to the stellar modeling,a nearly tenfold increase in the thermonuclear rate ratio of the break-out ^(19)F(p,γ)^(20) Ne reaction with respect to the competing ^(19)F(p,α)^(16) O back-processing reaction is required to reproduce the observed calcium *** performed a direct measurement of this break-out reaction at the China Jinping underground *** measurement was performed down to the low-energy limit of E_(c.m.)=186 keV in the center-of-mass *** key resonance was observed at 225.2 keV for the first *** a temperature of approximately 0.1 GK,this new resonance enhanced the thermonuclear ^(19)F(p,γ)^(20) Ne rate by up to a factor of≈7.4,compared with the previously recommended NACRE *** is of particular interest to the study of the evolution of the first stars and implies a stronger breakdown in their“warm”CNO cycle through the ^(19)F(p,γ)^(20) Ne reaction than previously *** break-out resulted in the production of the calcium observed in the oldest stars,enhancing our understanding of the evolution of the first stars.

关键词： Nuclear astrophysics First stars Abundance of calcium Reaction cross section Reaction rate China Jinping underground laboratory(CJPL) JUNA

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冰脊对极地冰下航道流场特性影响研究

船舶力学 2024年第7期28卷 1008-1017页

作者：孙盛石玉云李志富江苏科技大学船舶与海洋工程学院江苏镇江212001

冰脊是极地冰层下表面典型结构特征之一,掌握冰脊与冰下流场的相互作用规律,对于理解极地冰下航道适航特性及近冰面潜水器操纵运动具有重要的指导意义。为了探究冰脊对近冰面流场的影响及作用范围,本文基于极地实测数据建立五组典型分... 详细信息

冰脊是极地冰层下表面典型结构特征之一,掌握冰脊与冰下流场的相互作用规律,对于理解极地冰下航道适航特性及近冰面潜水器操纵运动具有重要的指导意义。为了探究冰脊对近冰面流场的影响及作用范围,本文基于极地实测数据建立五组典型分布间距冰脊流场,利用Fluent软件平台,通过稳态求解Reynolds应力方程模型(RSM)进行数值研究,重点分析冰脊间距对冰下流场特性的影响规律。同时,探究冰脊对冰下流场干扰的辐射深度。研究表明:连续冰脊对冰脊间尾涡具有拉伸效应;根据冰脊对冰下流场的干扰程度,辐射深度可分为强辐射区、稳定辐射区和无影响区三个区间。

关键词：冰脊冰下航道适航特性 RSM 尾涡