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Two-Detector Arbitrary NtH^(-)Order HBT-Type Ghost Diffraction

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Chinese Physics Letters 2012年第1期29卷 126-129页

作者： CAO Bin ZHANG Chun-Xi OU Pan LIN zhi-Li sun ming-Jie School of Instrumentation Science and Opto-electronics Engineering Beihang UniversityBeijing 100191

The imaging quality using two-detector arbitrary N th-order intensity correlation in optics is *** is theoretically demonstrated that with the order of intensity correlation N increases,the visibility of the retrieved image enhances promptly;and different n-fold intensity on one arm of the intensity correlation leads to different visibility,whereas the resolution is independent of N and *** numerical simulation results are shown to be consistent with our theoretical analysis ***,a particular imaging system of the two-detector N thorder Hanbury-Brown-Twiss(HBT)type ghost diffraction is conceived by using a slit as the object,the image quality by this type of ghost diffraction is *** experimental results coincide with our theoretical analysis.

关键词： ghost Ghost prompt

Zoledronate-loaded aluminum salt nanovaccines amplify cellular immune response by enhancing cross-presentation

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Nano Research 2025年第1期18卷 559-571页

作者： Chunting He Penghui He Xue Tang Shuting Bai ming Qin Yunting Zhang Zhaofei Guo Guangsheng Du Xun sun Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry West China School of PharmacySichuan UniversityChengdu 610041China

Being a Th2 stimulator,classic aluminum salt-based adjuvants only stimulate weak cellular immune responses that are required for vaccination against intracellular viruses or cancerous *** a thirdgeneration bisphosphonate,zoledronate(ZOL)can enhance antigen crosspresentation by inhibiting key enzymes of the mevalonate ***,we developed the subunit antigen ovalbumin(OVA)and ZOL co-loaded aluminum hydroxide nanoparticles(APN-OVA-ZOL)and investigated their capacity for inducing cellular immune responses against the *** results showed that the developed nanovaccines could successfully encapsulate OVA and ZOL,and enabled efficient lymph node *** by the mevalonate pathway inhibition effect of ZOL,APN-OVA-ZOL significantly promoted *** a result,APN-OVA-ZOL induced robust cellular immunity,including the activation of T and B *** a EG7-OVA tumor-bearing murine model,APN-OVA-ZOL significantly inhibited the tumor growth and prolonged mice *** work provided a strong empirical foundation indicating that zoledronate-loaded aluminum salt nanovaccines had a strong potency for cancer immunotherapy.

关键词： zoledronate(ZOL) mevalonate pathway antigen cross-presentation cellular immune responses

A Fast Interactive Sequential Pattern Mining Algorithm

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Wuhan University Journal of Natural Sciences 2006年第1期11卷 31-36页

作者： LU Jie-Ping LIU Yue-bo NI wei-wei LIU Tong-ming sun zhi-hui Department of Computer Science and Engineering Southeast University Nanjing 210096 JiangsuChina School of Electronics and Information Jiangsu University of Science and Technology Zhenjiang 212003Jiangsu China

In order to reduce the computational and spatial complexity in rerunning algorithm of sequential patterns query, this paper proposes sequential patterns based and projection database based algorithm for fast interactive sequential patterns mining algorithm （FISP）, in which the number of frequent items of the projection databases constructed by the correct mining which based on the previously mined sequences has been reduced. Furthermore, the algorithm＇s iterative running times are reduced greatly by using global-threshold. The results of experiments testify that FISP outperforms PrefixSpan in interactive mining

关键词： data mining sequential patterns interactive mining projection database

Homoclinic and Periodic Orbits Arising Near the Heteroclinic Cycle Connecting Saddle-focus and Saddle Under Reversible Condition

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Acta Mathematica Sinica,English Series 2007年第8期23卷 1495-1504页

作者： De ming ZHU Ying sun Department of Mathematics East China Normal University Shanghai 200062 P. R. China School of Science University of Ji'nan Ji'nan 250022 P. R. China

In this paper, we study the dynamical behavior for a 4-dimensional reversible system near its heteroclinic loop connecting a saddle-focus and a saddle. The existence of infinitely many reversible 1-homoclinic orbits to the saddle and 2-homoclinic orbits to the saddle-focus is shown. And it is also proved that, corresponding to each 1-homoclinic （resp. 2-homoclinic） orbit F, there is a spiral segment such that the associated orbits starting from the segment are all reversible 1-periodic （resp. 2-periodic） and accumulate onto F. Moreover, each 2-homoclinic orbit may be also accumulated by a sequence of reversible 4-homoclinic orbits.

关键词： reversible condition homoclinic orbit Poincare map periodic orbit saddle-focus

Distribution and Fate of Anthropogenic Nitrogen in the Calamagrostis angustifolia Wetland Ecosystem of Sanjiang Plain, Northeast China

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Journal of Integrative Plant Biology 2008年第4期50卷 402-414页

作者： zhi-Gao sun Jing-Shuang Liu Northeast Institute of Geography and Agricultural Ecology the Chinese Academy of Sciences Changchun 130012 China Graduate School of the Chinese Academy of Sciences Beijing 100039 China

Wetlands are important for the protection of water quality of rivers and lakes, especially those adjacent to agricultural landscapes, by intercepting and removing nutrients in runoff. In this study, the ^15N tracer technique was applied to study the distribution and fate of anthropogenic nitrogen （^15N-fertilizer） in Calamagrostis angustifolia Kom wetland plant-soil microcosms to identify the main ecological effects of it. ^15NH4^15NO3 solution （14.93 mg N/L, 20.28 at.% ^15N） was added to each microcosm of the first group, which was approximate to the current nitrogen concentration （CNC） of farm drainage, and 29.86 mg NIL ^15NH4^15NO3 solution was added to another group, which was approximate to the double nitrogen concentration （DNC） of farm drainage, while no nitrogen （NN） was added to the third group. The results suggest that the input of anthropogenic nitrogen has positive effects on the biomass and total nitrogen content of plant, and the positive effects will be elevated as the increase of its input amount. The increase of ^15N-fertilizer can also elevate its amounts and proportions in plant nitrogen. Soil nitrogen is still the main source of plant nitrogen, but its proportion will be reduced as the increase of ^15 N-fertilizer. The study of the fate of ^15N-fertilizer indicates that, in CNC treatment, only a small proportion is water-dissolved （0,13 ± 0.20%）, a considerable proportion is soil-immobilized （17.02 ± 8.62%）, or plant-assimilated （23.70 ± 0.92%）, and most is lost by gaseous forms （59.15 ± 8.35%）. While in DNC treatment, about 0.09 ± 0.15% is water-dissolved, 15.33 ± 7.46% is soil-immobilized, 23.55±2.86% is plant-assimilated, and 61.01±5.59% is lost by gaseous forms. The double input of anthropogenic nitrogen can not elevate the proportions of plant-assimilation, soil-immobilization and water-dissolution, but it can enhance the gaseous losses.

关键词： ^15N Tracer technique agricultural runoff Calamagrostis angustifolia wetland distribution and fate Sanjiang Plain.

Relationship between chloride diffusivity and pore structure of hardened cement paste

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第5期12卷 360-367页

作者： Guo-wen sun Wei sun Yun-sheng ZHANG zhi-yong LIU Jiangsu Key Laboratory of Construction Materials.Southeast University Nanjing 211189china

Based on effective media theory, a predictive model, relating chloride diffusivity to the capillary pores, gel pores, tortuosity factor, and pore size distribution of hardened cement, is proposed. To verify the proposed model, the diffusion coefficient of chloride ions, the degree of hydration, and peak radius of capillary pores of cement paste specimens were measured. The predicted results for chloride diffusivity were compared with published data. The results showed that the predicted chloride diffusivity of hardened cement paste was in good agreement with the experimental results. The effect of the evolution of pore structures in cement paste on chloride diffusivity could be deduced simultaneously using the proposed model.

关键词： Hardened cement paste Chloride diffusivity Porosity Tortuosity factor Constrictivity Key words: Hardened cement paste, Chloride diffusivity, Porosity, Tortuosity factor, Conslrictivity

Extraordinary response of metastatic pancreatic cancer to apatinib after failed chemotherapy: A case report and literature review

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World Journal of Gastroenterology 2017年第41期23卷 7478-7488页

作者： Cheng-ming Li zhi-Chao Liu You-Ting Bao Xin-Dong sun Lin-Lin Wang School of Medicine and Life Sciences University of Jinan-Shandong Academy of Medical Sciences Department of Radiation Oncology Shandong Cancer Hospital Affiliated to Shandong University Shandong Academy of Medical Sciences Department of Oncology Weifang Medical University School of Medicine Shandong University

Chemotherapy has limited efficacy in the treatment of advanced and metastatic pancreatic cancer(PC), and has serious side effects. The development of novel effective agents, especially targeted therapy, is essential for patients with PC. We present a 58-year-old Chinese woman initially diagnosed with locally advanced PC. As the disease progressed to Stage Ⅳ, the patient was unable to tolerate chemotherapy after the fourth-line treatment. She was then treated with apatinib, a novel and highly selective tyrosine kinase inhibitor of vascular endothelial growth factor receptor-2 and achieved a progression-free-survival of 7 mo. All drug-related side effects were well controlled with medication. To the best of our knowledge, this is the first case of PC which responded to apatinib. Considering this remarkable response, apatinib may be a promising agent in the treatment of PC. We also reviewed the literature on chemotherapy and targeted therapy, especially the anti-angiogenesis therapy for patients with PC, and investigated the effect of apatinib in other solid tumors as well.

关键词： Anti-angiogenesis Apatinib Pancreatic cancer Targeted therapy Vascular endothelial growth factor receptor-2

Existence and Multiplicity of Solutions for Nonlocal Systems with Kirchhoff Type

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Acta Mathematicae Applicatae Sinica 2016年第1期32卷 35-54页

作者： zhi-tao ZHANG Yi-min sun Academy of Mathematics and Systems Science Chinese Academy of Sciences School of Mathematics Northwest University

Firstly,we use Nehari manifold and Mountain Pass Lemma to prove an existence result of positive solutions for a class of nonlocal elliptic system with Kirchhoff *** a multiplicity result is established by cohomological index of Fadell and *** also consider the critical case and prove existence of positive least energy solution when the parameter β is sufficiently large.

关键词： Critical point Nehari manifold cohomological index

Dynamic generation of entangling wave packets in XY spin system with decaying long-range couplings

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Science China(Physics,Mechanics & Astronomy) 2008年第1期51卷 45-55页

作者： YANG Shuo SONG zhi sun ChangPu Department of Physics Nankai UniversityTianjin 300071China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100080China

The dynamic generation of spin entanglement between two distant sites in a XY model with 1/r 2 decay long-range couplings was *** to the linear dispersion relationε(k)~|k|of magnons in such a model,a well-located spin state can be dynamically split into two moving entangled local wave packets without changing their ***,when such two wave packets meet at the diametrically opposite site after the fast periodτ=Nπ/J,the initial well-located state is completely *** calculation was performed to confirm the analytical result even if the ring system of sizes N up to several thousands is *** truncation approximation for the coupling strengths was also *** simulation shows that the above conclusions still hold even if the range of the coupling strength is truncated to a relatively short scale compared with the size of the spin system.

关键词： quantum information entanglement spin model