检索结果-南通市图书馆

Serum Helicobacter pylori Kat A and Ahp C antibodies as novel biomarkers for gastric cancer

World Journal of gastroenterology 2016年第21期22卷 5060-5067页

作者： Bing Zhang Hai-Lin Li qing Fan Fang guo xi-Yun Ren Hai-Bo Zhou Ji-Wei zhu Ya-Shuang Zhao Wen-Jing Tian Department of Epidemiology College of Public Health Harbin Medical University Harbin 150081 Heilongjiang Province China xiangfang Center for Disease Control and Prevention Harbin 150081 Heilongjiang Province China Department of Forensic Medicine Harbin Medical University Harbin 150081 Heilongjiang Province China

AIM: To investigate catalase (KatA) and alkyl hydroperoxide reductase (AhpC) antibodies of Helicobacter pylori as biomarkers for gastric cancer (gC). METHODS: This study included 232 cases and 264 controls. Recombinant KatA and AhpC proteins were constructed and the levels of antibodies were tested by indirect enzyme-linked immunosorbent assay (ELISA). Logistic regression was applied to analyze the relationships between KatA, AhpC and gC. The chi(2) trend test was used to evaluate the dose-response relationships between serum KatA and AhpC antibody levels and gC. Receiver operating characteristic (ROC) curve was used to evaluate the screening accuracy of KatA and AhpC as biomarkers. Combined analysis was used to observe screening accuracy of predictors for gC. RESULTS: In all subjects, the association between KatA and AhpC and gC risk was significant (P gly related to gC risk with a dose-dependent effect (P for trend g a sensitivity of 66.81% and specificity of 86.36%; and the AUC for AhpC was 0.615, with a sensitivity of 75.65% and specificity of 45.49%. The AUC was 0.906 for KatA and flagella protein A (FlaA) combined analysis. CONCLUSION: Serum KatA and AhpC antibodies are associated with gC risk and KatA may serve as a biomarker for gC. KatA/FlaA combined analysis improved screening accuracy.

关键词： Helicobacter pylori Catalase Serum antibody Alkyl hydroperoxide reductase gastric cancer Case-control study

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

松潘-甘孜地体青海吾和玛高分异Ⅰ型花岗岩的识别与岩石成因

引用

地质通报 2024年第5期43卷 789-801页

作者：陈敏王雁鹤谷强马庆青海大学地质工程系青海西宁810016 中国地质调查局西宁自然资源综合调查中心青海西宁810000 中国地质调查局西安矿产资源调查中心陕西西安710100

为探讨松潘-甘孜地体内青海吾和玛花岗质岩石的成因类型与岩石成因,对其开展了岩相学、地球化学、锆石U-Pb年代学和Lu-Hf同位素等研究。吾和玛花岗质岩石被确定为高分异的Ⅰ型花岗岩,其结晶年龄为216.6±4.3 Ma,为正长花岗岩,具有弱过... 详细信息

为探讨松潘-甘孜地体内青海吾和玛花岗质岩石的成因类型与岩石成因,对其开展了岩相学、地球化学、锆石U-Pb年代学和Lu-Hf同位素等研究。吾和玛花岗质岩石被确定为高分异的Ⅰ型花岗岩,其结晶年龄为216.6±4.3 Ma,为正长花岗岩,具有弱过铝质高钾钙碱性特征。岩石轻、重稀土元素分馏不明显((La/Yb)_(N)ba、Sr和高场强元素Nb、Ta、P、Ti,富集大离子亲石元素Rb、Th、U、K,ε_(Hf)(t)值为-2.54~1.32。吾和玛花岗质岩石的母岩浆是岩石圈拆沉作用引起软流圈上涌,诱发中元古代地壳物质(类似于变杂砂岩的物质)部分熔融形成长英质母岩浆,后期又受到斜长石、钾长石、磷灰石等矿物分离结晶作用的控制,经历了高程度的分异形成的。

关键词：高分异Ⅰ型花岗岩锆石U-Pb Lu-Hf同位素松潘-甘孜地体地质调查工程青海

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Allele-specific expression analyses reveal immune divergences between ibex and goat species

引用

Zoological Research 2022年第4期43卷 671-674页

作者： zhi-Rui Yang Jia-xin Li zhu-qing Zheng Chen Zhao Yu Wang Ming Li Hojjat Asadollahpour Nanaei Xue-Lei Dai Yun-Jia Li Ran Li Chun-Na Cao Mao Li Yu Jiang Wen-xin Zheng xi-Hong Wang Key Laboratory of Animal genetics Breeding and Reproduction of Shaanxi ProvinceCollege of Animal Science and TechnologyNorthwest A&F UniversityYanglingShaanxi 712100China Department of Animal Science Faculty of AgricultureShahid Bahonar University of KermanKermanPB 76169-133Iran Tropical Crops genetic Resources Institute Chinese Academy of Tropical Agricultural SciencesDanzhouHainan 571700China xinjiang Academy of Animal Sciences UrumqiXinjiang 830011China

DEAR EDITOR,Understanding the different immune responses of wild and domestic caprid species is critical for addressing certain zoonotic *** this study,we generated blood transcriptomes of 13 Siberian ibex and domestic goat hybrids and performed allele-specific expression and splicing *** showed that genes exhibiting significant imbalance between the ibex and goat were highly related to the Toll-like receptor(TLR),antigen recognition,and immune activation *** genomic analysis of the species revealed that immune function-related genes were under strong selection pressure in the domestic goat.

关键词： immune allele divergence

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Discovery of the Mid-Late Jurassic volcanic rocks(163.4 Ma) in Nanhuangcheng Island, Shandong Province, China

引用

China geology 2022年第1期5卷 191-192页

作者： xiao-qing zhu Ming-jian Wang xi Mei zhi-xian Tian Shi-pu Bi Long Huang qingdao Institute of Marine geology China Geological SurveyMinistry of Natural ResourcesQingdao 266071China Laboratory for Marine Mineral Resources Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China

*** cha.gshan Islands are located on the geographical boundary between the Bohai Sea and the North Yellow Sea,*** tectonic deformation developed in this area,which is an important connection point to study the tectonics of the Shandong Peninsula and Liaoning *** studies have shown that the lithologies of the three northern islands(Beihuangcheng Island,Nanhuangcheng Island,and xiaoqin Island)of the cha.gshan Islands include Neoproterozoic quartzite,phyllite,and slate(Fuzikuang Formation of the Penglai group),and a few areas are covered by Quaternary slope deposits,marine deposits and loess(Fig.1 a;Qiao EW et al.,2019).Recently,a set of volcanic rocks was firstly discovered in Nanhuangcheng Island(Fig.1 a).

关键词： Island Jurassic loess

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Monolithic 0–f Scheme-based Frequency Comb Directly Driven by a High-Power Ti:Sapphire Oscillator

引用

Chinese Physics Letters 2020年第5期37卷 47-50页

作者： Jian-Wang Jiang Shao-Bo Fang Zi-Yue Zhang Jiang-Feng zhu Hai-Nian Han guo-qing cha.g zhi-Yi Wei School of Physics and Optoelectronic Engineering Xidian UniversityXi'an 710071 Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190 University of Chinese Academy of Sciences Beijing 100049 Songshan Lake Material Laboratory Dongguan 523808

A monolithic O-f scheme-based femtosecond optical frequency comb directly driven by a high-power Ti:sapphire laser oscillator is *** spectrum covering from 650 nm to 950 nm is generated from the Ti:sapphire oscillator with a repetition rate of 170 *** average output power up to 630 mW is delivered under the pump power of 4.5 W.A 44-dB signal-to-noise ratio(SNR)of the carrier-envelope phase offset(CEO)beat note is achieved under the resolution of 100 kHz and is long-term stabilized to a reference source at 20 *** integrated phase noise(IPN)in the range from 1 Hz to 1 MHz is calculated to be 138 mrad,corresponding to the timing jitter of 63 as at the central wavelength of 790 nm.

关键词： pump oscillator noise

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Lipoprotein(a) as a Marker for Predicting the Presence and Severity of Coronary Artery Disease in Untreated Chinese Patients Undergoing Coronary Angiography

引用

Biomedical and Environmental Sciences 2018年第4期31卷 253-260页

作者： SUN Di ZHAO xi LI Sha ZHANg Yan WU Na Qiong zhu Cheng gang gUO Yuan Lin gAO Ying qing Ping LIU geng DONg Qian LI Jian Jun Division of Dyslipidemia State Key Laboratory of Cardiovascular Disease Fu Wai Hospital National Center for Cardiovascular Disease Chinese Academy of Medical Sciences and Peking Union Medical College

Objective Low-density lipoprotein cholesterol（LDL-C） has been well known as the risk factor of coronary artery disease（CAD）. However, the role of lipoprotein（a） [Lp（a）] in the development of CAD is of great interest but still controversial. Thus, we aim to explore the effect of Lp（a） on predicting the presence and severity of CAD in Chinese untreated patients, especially in combination with LDL-C. Methods We consecutively recruited 1,980 non-treated patients undergoing coronary angiography, among which 1,162 patients were diagnosed with CAD. gensini score（gS） was used to assess the severity of CAD. Lp（a） was measured by immunoturbidimetric method. Results Patients with CAD had higher level of LDL-C and Lp（a） compared with non-CAD（P 〈 0.05）. Multivariable logistic regression revealed that Lp（a）〉 205 mg/L（highest tertile） predicted 1.437-fold risk for CAD（95% CI： 1.108-1.865, P = 0.006） and 1.480-fold risk for high gS（95% CI： 1.090-2.009, P = 0.012） respectively. Interestingly, concomitant elevated level of Lp（a） and LDL-C conferred the highest risk for both presence [OR = 1.845, 95% CI： 1.339-2.541, P 〈 0.001] and severity [OR = 1.736, 95% CI： 1.188-2.538, P = 0.004] of CAD. Conclusion Lipoprotein（a） is a useful marker for predicting the presence and severity of CAD, especially combined with LDL-C.

关键词： Lipoprotein(a) LDL-C Coronary artery disease Chinese

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Principle of diffraction enhanced imaging (DEI) and computed tomography based on DEI method

引用

Nuclear Science and Techniques 2006年第6期17卷 342-353页

作者： zhu Pei-Ping HUANg Wan-xia YUAN qing-xi YU Jian WANg Jun-Yue ZHENg xin SHU Hang CHEN Bo LIU Yi-Jin LI En-Rong WU Zi-Yu Beijing Synchrotron Radiation Facility Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China Electronic Institute of Dalian University of Technology Dalian 116023 China

In the first part of this article a more general DEI equation was derived using simple concepts. Not only does the new DEI equation explain all the problems that can be done by the DEI equation proposed by chapman, but also explains the problem that can not be explained with the old DEI equation, such as the noise background caused by the small angle scattering reflected by the analyzer. In the second part, a DEI-PI-CT formula has been proposed and the contour contrast caused by the extinction of refraction beam has been qualitatively explained, and then based on the work of Ando's group two formulae of refraction CT with DEI method has been proposed. Combining one refraction CT formula proposed by Dilmanian with the two refraction CT formulae proposed by us, the whole framework of CT algorithm can be made to reconstruct three components of the gradient of refractive index.

关键词：衍射放大成像 X线断层摄影术 DEI法辐射探测技术

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Improved Kalman filter method considering multiple factors and its application in landslide prediction

引用

Frontiers of Earth Science 2020年第3期14卷 625-636页

作者： qing Ling Wei Qu Qin Zhang Lingjie Kong Jing Zhang Li zhu College of geology Engineering and geomatics Chang’an UniversityXi’an710064China School of Civil Engineering Lanzhou University of TechnologyLanzhou730050China Information Engineering University Zhengzhou450002China

Landslides,seriously threatening human lives and environmental safety,have become some of the most catastrophic natural disasters in hilly and mountainous areas ***,it is necessary to forecast landslide deformation for landslide risk *** paper presents a method of predicting landslide displacement,i.e.,the improved multi-factor Kalman filter(KF)*** developed model has two advantages over the traditional KF ***,it considers multiple external environmental factors(e.g.,rainfall),which are the main triggering factors that may induce slope ***,the model includes random disturbances of *** proposed model was constructed using a time series which consists of over 16-month of data on landslide movement and precipitation collected from the Miaodian loess landslide monitoring system and nearby meteorological stations in Shaanxi province,*** validation was performed by predicting movements for periods of up to 7 months in the *** performance of the developed model was compared with that of the improved single-factor KF,multi-factor KF,multi-factor radial basis function,and multi-factor support vector regression *** results show that the improved multi-factor KF method outperforms the other models and that the predictive capability can be improved by considering random disturbances of triggers.

关键词： landslide improved Kalman filter triggering factors displacement prediction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

问题导向的“钢结构设计原理”课堂理论教学改革

引用

教育教学论坛 2024年第15期 73-76页

作者：朱伟庆刘永健陈峰长安大学公路学院陕西西安710064

“钢结构设计原理”是道路桥路与渡河工程专业的核心专业课程,扎实提升课堂理论教学效率和效果是该课程教学改革的重要任务和目标。细致分析“钢结构设计原理”的课程内容特点以及由此导致学生学习过程中存在的问题,有针对性地提出从多... 详细信息

“钢结构设计原理”是道路桥路与渡河工程专业的核心专业课程,扎实提升课堂理论教学效率和效果是该课程教学改革的重要任务和目标。细致分析“钢结构设计原理”的课程内容特点以及由此导致学生学习过程中存在的问题,有针对性地提出从多层次网格模块化教学内容、建立“思维主线”、引入真实工程案例、坚持精确理论推导与定性分析相结合、开展课程横向比较等方面开展课堂理论教学改革,进而从根本上提升课堂理论教学的效率与效果。

关键词：钢结构设计原理问题导向课程特点模块化思维主线

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High Ratio of Polyembryonic Seeds Was Observed in Monoembryonic Kiyomi Tangor X Ponkan and Molecular Evidences Against Asexual Origin of Polyembryos

引用

Agricultural Sciences in China 2003年第5期2卷 561-565页

作者： HONg Qi-bin, LI xi-qing, JIANg Dong, CHEN zhu-sheng, xiANg Su-qiong,gONg gui-zhi and YE qing-liangCitrus Research Institute, Chinese Academy of Agricultural Sciences , Chongqing 400712 , P.R.China Citrus Research Institute Chinese Academy of Agricultural Sciences Chongqing 400712 P. R. China

Polyembryony is a serious handicap in citrus breeding. To obtain zygotic off-springs, monoem-bryonic seed parents were usually used in breeding programs. Kiyomi, a superior monoembryonic tangor, was used as seed parent in 7 cross combinations. When pollen parents was chandler pummelo or Tarocco blood orange, only monoembryonic seeds were observed. However, when Washington Sanguine, Li-xing orange and Bing-tang orange were used as pollen parents, no more than 7. 2% of polyembryonic seeds were observed. Interestingly, while male parents were Nucellar3 Ponkan and Oota Ponkan, high ratio of polyembryonic seeds was observed. The ratio of polyembryonic seeds was steadily at about 30 % in two consecutive years and was obviously different from other results reported. Polyembronic seeds were observed in monoembryonic varieties sometimes, but normally their ratios were no more than 7%. Polyembryonic-seedlings were got by separating the multi-embryos in seeds of Kiyomi×Nucellar3 Ponkan and then their leaves were used in RAPD analysis. Identical bands of male parent and/or different bands from seed parent were found in most of the polyembryonic-seedlings and so it can be sure that these seedlings were of zygotic origin. Some pairs of polyembryonic-seedlings have identical bands in all tested primers and may be resulted from zygotic embryo divisions. Different bands were found in other pairs of polyembryonic-seedlings also and this may indicate multi-egg fertilization or other source of variation.

关键词： Citrus Polyembryony RAPD Breeding

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：