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Rare Metals 2024年第9期43卷 4356-4366页

作者： Qin-Ke Tang Jiang-Chuan liu Rui Shi Yun-Feng Zhu Ji-Guang Zhang Ya-Na liu Jun Wang Yao Zhang Xiao-Hui Hu zhi-bin liu Li-Quan Li College of Materials Science and Engineering Jiangsu Collaborative Innovation Centre for Advanced Inorganic Function CompositesNanjing Tech UniversityNanjing 211816China School of Materials Science and Engineering Southeast UniversityNanjing 211189China

Magnesium-based hydrides have been widely recognized as an appropriate choice for solid-state hydrogen ***,its undesirable thermodynamics and sluggish hydrogenation/dehydrogenation kinetics are major bottlenecks for its ***,a highly stable and highly dispersed Ni-based catalyst(Ni/Al_(2)O_(3)/GN)was fabricated to promote the hydrogen storage performance of MgH_(2)via the electrostatic effect of NiAl-LDH/GN precursor with a co-calcination reduction ***_(2)-5wt%Ni/Al_(2)O_(3)/GN exhibits excellent hydrogen storage performance,releasing about 5.7 wt%hydrogen in 3500 s at 250℃,and can reach a saturation hydrogen absorption of about 6.15 wt%in 3000 s at 100℃.Furthermore,it also shows low dehydrogenation apparent activation energy of 89.1 and 118.2 kJ·mol^(-1).Impressively,the catalyst ensures the stability of both the physical phase and structure during ball milling and cycling *** role of each phase in Ni/Al_(2)O_(3)/GN on the hydrogen storage performance of MgH_(2)was also discussed through experiments and theoretical calculation,and the synergistic catalytic mechanism of Ni/Al_(2)O_(3)/GN was clearly *** work provides a unique perspective for the preparation of highly stable and highly dispersible catalysts.

关键词： Magnesium hydride Ni/Al_(2)O_(3)/GN Hydrogen storage performance Catalytic mechanism

Microstructure,interfacial reaction behavior,and mechanical properties of Ti_3AlC_(2)reinforced Al6061 composites

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Transactions of Nonferrous Metals Society of China 2024年第9期34卷 2756-2771页

作者： zhi-bin liu Jia-bao BAO Wen-jie HU Hong YAN School of Advanced Manufacturing Nanchang UniversityNanchang 330031China Jiangxi Vocational and Technical College of Communications Nanchang 330013China

The interfacial reaction behavior of Al and Ti_3AlC_(2)at different pouring temperatures and its effect on the microstructure and mechanical properties of the composites were *** results show that the addition of3.0 wt.%Ti_3AlC_(2)refines the average grain size ofα(Al)in the composite by 50.1%compared to Al6061 *** analyses indicate that an in-situ Al_(3Ti)transition layer of-180 nm in thickness is generated around the edge of Ti_3AlC_(2)at 720℃,forming a well-bonded Al-Al_(3Ti)*** this processing temperature,the ultimate tensile strength of A16061-3.0 wt.%Ti_3AlC_(2)composite is 199.2 MPa,an improvement of 41.5%over the Al6061 *** analyses further elucidate that 720℃is favourable for forming the nano-sized transition layer at the Ti_3AlC_(2)***,the thermal mismatch strengthening plays a dominant role in this state,with a strengthening contribution of about 74.8%.

关键词： Al6061 composites Ti3AlC2 microstructure interfacial reaction tensile mechanical properties

Effectiveness and safety of traditional Chinese medicine in treating acquired immune deficiency syndrome: 2004–2014

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Infectious Diseases of Poverty 2015年第1期4卷 506-511页

作者： zhi-bin liu Ji-Ping Yang Li-Ran Xu Department of Acquired Immune Deficiency Syndrome Treatment and Research Center the First Affiliated Hospital of Henan University of Traditional Chinese Medicine19 Ren Min RoadZhengzhou 450000HenanChina Discipline of Internal Chinese Medicine the First Affiliated Hospital of Henan University of Traditional Chinese MedicineZhengzhouHenanChina Department of Cellular Immunology Laboratory Key Laboratory of Viral Diseases Prevention and Treatment of Traditional Chinese Medicine of Henan ProvinceZhengzhou 450000HenanChina

Substantial progress has been made in China in using traditional Chinese medicine(TCM)to treat acquired immune deficiency syndrome(AIDS).Our objective was to review the latest developments in TCM treatment of AIDS in China between 2004 and *** reviewed the content of original articles investigating the efficacy and safety of TCM for treating AIDS published in Chinese and English language *** references from 2004 to 2014 were found using PubMed and the China National Knowledge Infrastructure *** found that TCM has been widely used for treating AIDS and its complications in *** number of TCM studies has increased,which indicates efficacy and *** of efficacy in the reviewed articles included the alleviation of human immunodeficiency virus(HIV)-related signs and symptoms,improvements in quality of life,improvements in long-term survival,counteraction of the adverse side effects of antiviral drugs,promotion of immune reconstitution,and improvement of laboratory *** sum,the literature indicates that TCM is *** plays an important role in the treatment of *** studies have attempted to measure the efficacy and safety of TCM for treating AIDS,but more evidence is ***,more research on this topic is required in the future.

关键词： HIV/AIDS Traditional Chinese medicine Antiretroviral therapy Herbal medicine Quality of life Survival Immune reconstitution

Facile fabrication of porous pure and Ag nanoparticle-doped poly(4-vinylpyridine) films at the liquid-liquid interfaces

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Chinese Chemical Letters 2011年第7期22卷 867-870页

作者： zhi bin Ren Jiang liu Yu Ping Chen Meng Chen Dong Jin Qian Department of Chemistry Fudan University Shanghai 200433 China

We reported an interfacial self-assembly of regularly layered porous poly（4-vinylpyridine）（P4VP） films at the interfaces of water-chloroform or -dichloroethane. The porous diameters were in the range from hundred nanometers to several micrometers. It was revealed that formation of such kind of porous materials was solvent dependent. Moreover, cyclic Ag nanoparticles could be grown in the porous P4VP films to form Ag-P4VP nanohybrids under radiation.

关键词： Self-assembly Interface Porous films Nanohybrids

Using the SELDI ProteinChip System to Detect Changes in Protein Expression in Vero Cells after Infection

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中国病毒学 2007年第1期22卷 68-73页

作者： zhi-jun liu bin WANG zhi-yong YAN Xu-xia SONG Dong-meng QIAN zhi-qiang BAI Department of Microbiology Qingdao Medical College and Key Laboratory of Medicine and Biotechnology of Qingdao Qingdao University Medical College Qingdao 266021China

人的疱疹单一的病毒(HSV-1 ) 1 引起美容，眼睛，并且 encephalitic 疾病并且与潜伏的感染和癌症被联系。这里，我们开发了由使用 SELDI 蛋白质薄片在在 vitro 有教养的 Vero 房间检测蛋白质表示的变化在蛋白质水平学习 HSV-1 感染的致... 详细信息

人的疱疹单一的病毒(HSV-1 ) 1 引起美容，眼睛，并且 encephalitic 疾病并且与潜伏的感染和癌症被联系。这里，我们开发了由使用 SELDI 蛋白质薄片在在 vitro 有教养的 Vero 房间检测蛋白质表示的变化在蛋白质水平学习 HSV-1 感染的致病的一个工具。在有为 12， 24 或 48 h 的 HSV-1 和文化的感染以后，房间被收获并且 lysed。IMAC3 数组被用于 SELDI-TOF-MS 在感染前后检测 proteomic 差别。薄片检测了一系列差别表示蛋白质山峰。有趣地，在 16 912 Da 的山峰和 17 581 Da 与 ISG15 的分子的团精确相应，它可以在感染的过程期间参予抗病毒的活动。因此，我们获得了的结果能用作一个基础学习在病毒和它的主人之间的 HSV-1 和相互作用的致病。另外，他们能为 HSV-1 感染的治疗在新治疗学的目标的发现帮助。关键词 SELDI 蛋白质薄片 - Vero 房间 - HSV-1 - 蛋白质表达式 CLC 数字 R373 基础项目：中国(30540075 ) 的国家自然科学基础；

关键词： SELDI Protein Chip Vero Cells HSV-1 Protein Expression

Experimental investigation on fluid-induced slip behavior of fault filled with fault gouge

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第9期16卷 3661-3672页

作者： Yongshui Kang zhi Geng bin liu Youqi Huang State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071China University of Chinese Academy of Sciences Beijing100049China

Fault zones are usually filled with fault gouge and accompanied by fault *** coupled effect of fault gouge and water significantly impacts the slip behavior of the fault,which may weaken the fault structure and further induce rupture propagation and *** this study,we carried out a laboratory experiment to investigate the fluid-induced slip behavior of fault filled with *** friction evolution characteristic associated with fluid pressure and effective stress was investigated during the slip *** addition,the role transformation process of the gouge on the slip behavior of fault was *** experimental result indicates that the friction on the filled fault surface is significantly affected by fault *** rupture of the gouge promotes fault slip and the fluid pressure plays a vital role in the initiation of fault *** fault gouge enhances the shearing strength of the fault and acts as a barrier before the initial slip under fluid ***,the fault gouge would accelerate the fault slip and transform into lubricant after the initial slip.

关键词： Fault gouge Fluid Slip behavior Friction Shear strength

Microdynamic mechanical properties and fracture evolution mechanism of monzogabbro with a true triaxial multilevel disturbance method

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International Journal of Mining Science and Technology 2024年第3期34卷 385-411页

作者： zhi Zheng bin Deng Hong liu Wei Wang Shuling Huang Shaojun Li State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures Key Laboratory of Disaster Prevention and Structural Safety of Ministry of EducationCollege of Civil Engineering and ArchitectureGuangxi UniversityNanning 530004China State Key Laboratory of Geomechanics and Geotechnical Engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan 430071China Key Laboratory of Ministry of Education for Geomechanics and Embankment Engineering Hohai UniversityNanjing 210098China Key Laboratory of Geotechnical Mechanics and Engineering of Ministry of Water Resources Changjiang River Scientific Research InstituteWuhan 430015China

The far-field microdynamic disturbance caused by the excavation of deep mineral resources and underground engineering can induce surrounding rock damage in high-stress conditions and even lead to ***,the mechanical properties and damage/fracture evolution mechanisms of deep rock induced by microdynamic disturbance under three-dimensional stress states are ***,a true triaxial multilevel disturbance test method is proposed,which can completely simulate natural geostress,excavation stress redistribution(such as stress unloading,concentration and rotation),and subsequently the microdynamic disturbance triggering damaged rock *** on a dynamic true triaxial test platform,true triaxial microdynamic disturbance tests under different frequency and amplitudes were carried out on *** results show that increasing amplitude or decreasing frequency diminishes the failure strength of *** modulus gradually decreases during disturbance *** frequency and amplitude increase,the degradation rate of deformation modulus decreases slightly,disturbance dissipated energy increases significantly,and disturbance deformation anisotropy strengthens obviously.A damage model has been proposed to quantitatively characterize the disturbance-induced damage evolution at different frequency and amplitude under true triaxial *** disturbance failure,the micro-tensile crack mechanism is dominant,and the micro-shear crack mechanism increases significantly at *** the increase of amplitude and frequency,the micro-shear crack mechanism *** approaching disturbance failure,the acoustic emission fractal dimension changes from a stable value to local large oscillation,and finally increases sharply to a high value at ***,the disturbance-induced failure mechanism of surrounding rock in deep engineering is clearly elucidated.

关键词： True triaxial disturbance test Mechanical properties Fracture evolution mechanism Disturbance-induced damage evolution Failure mechanism and precursor

Adaptive Algorithms on Maximizing Monotone Nonsubmodular Functions

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Journal of the Operations Research Society of China 2024年第2期12卷 428-445页

作者： bin liu Hui Su Shu-Fang Gong Qi-zhi Fang School of Mathematical Sciences Ocean Universityof ChinaQingdao266100ShandongChina

Submodular optimization is widely used in large *** order to speed up the problems solving,it is essential to design low-adaptive algorithms to achieve acceleration in *** general,the function values are given by a value oracle,but in practice,the oracle queries may consume a lot of ***,how to strike a balance between optimizing them is *** this paper,we focus on maximizing a normalized and strictly monotone set function with the diminishing-return ratio under a cardinality constraint,and propose two algorithms to deal with *** apply the adaptive sequencing technique to devise the first algorithm,whose approximation ratio is arbitrarily close to 1-e^(-γ)in O(logn·log(log k/γ)) adaptive rounds,and requires O(logn^(2)·log(log k/γ)) *** by adding preprocessing and parameter estimation steps to the first algorithm,we get the second *** second algorithm trades a small sacrifice in adaptive complexity for a significant improvement in query *** the same approximation and adaptive complexity,the query complexity is improved *** the best of our knowledge,this is the first paper of designing adaptive algorithms for maximizing a monotone function using the diminishing-return ratio.

关键词： Approximation algorithm Adaptivity Nonsubmodular maximization Cardinality constraint

Gut-targeted therapies for type 2 diabetes mellitus: A review

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World Journal of Clinical Cases 2024年第1期12卷 1-8页

作者： Tian-Cheng Xu Yun liu zhi Yu bin Xu Key Laboratory of Acupuncture and Medicine Research of Ministry of Education Nanjing University of Chinese MedicineNanjing 210023Jiangsu ProvinceChina

Type 2 diabetes mellitus(T2DM)is a chronic metabolic disorder characterized by hyperglycemia and insulin *** global prevalence of T2DM has reached epidemic proportions,affecting approximately 463 million adults worldwide in *** treatments for T2DM include lifestyle modifications,oral antidiabetic agents,and insulin ***,these therapies may carry side effects and fail to achieve optimal glycemic control in some ***,there is a growing interest in the role of gut microbiota and more gut-targeted therapies in the management of *** gut microbiota,which refers to the community of microorganisms that inhabit the human gut,has been shown to play a crucial role in the regulation of glucose metabolism and insulin *** in gut microbiota composition and diversity have been observed in T2DM patients,with a reduction in beneficial bacteria and an increase in pathogenic *** dysbiosis may contribute to the pathogenesis of the disease by promoting inflammation and impairing gut barrier *** gut-targeted therapies have been developed to modulate the gut microbiota and improve glycemic control in *** potential approach is the use of probio-tics,which are live microorganisms that confer health benefits to the host when administered in adequate *** randomized controlled trials have demonstrated that certain probiotics,such as Lactobacillus and Bifidobacterium species,can improve glycemic control and insulin sensitivity in T2DM *** may include the production of short-chain fatty acids,the improvement of gut barrier function,and the reduction of *** gut-targeted therapy is fecal microbiota transplantation(FMT),which involves the transfer of fecal material from a healthy donor to a *** has been used successfully in the treatment of Clostridioides difficile infection and is now being investigated as a potential therapy for T2DM.A recent rand

关键词： Type 2 diabetes mellitus Gastroenterology Bacteria Implanted device

Secoemestrin C Ameliorates Psoriasis-like Skin Inflammation in Mice by Suppressing the TNF-α/NF-κB Signaling Pathway

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Current Medical Science 2024年第1期44卷 232-240页

作者： zhi-bin ZHU Meng-jie liu Jing WANG Zhou SHU Jie CAO Department of Stomatology Chengdu Seventh People's HospitalChengdu 610044China Department of Pharmacy Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

Objective Secoemestrin C(SC),an epitetrathiodioxopiperazine isolated from Aspergillus nidulans,has been previously reported to have immunomodulatory and hepatoprotective effects against acute autoimmune ***,the effect of SC on regulating the inflammation and its underlying mechanisms in the pathogenesis of psoriasis remain *** study aimed to evaluate the effects of SC on inflammatory dermatosis both in vitro and in *** In vitro,HaCaT cells were induced with tumor necrosis factor-alpha(TNF-α,10 ng/mL)to establish an inflammatory injury model,and the expression of nuclear transcription factor-κB(NF-κB)pathway components was measured using qRT-PCR and Western *** in vivo mouse model of imiquimod(IMQ)-induced psoriasis-like skin inflammation was used to evaluate the effectiveness of SC in alleviating *** SC significantly blocked the activation of NF-κB signaling in TNF-α-stimulated HaCaT *** addition,systemic and local administration of SC improved psoriatic dermatitis in the IMQ-induced mouse *** reduced skin scale and significantly inhibited the secretion of inflammatory factors in skin *** The protective effect of SC against psoriatic-associated inflammation reveals its potential therapeutic value for treating psoriasis.

关键词： secoemestrin C(SC) psoriasis tumor necrosis factor-alpha(TNF-α) nuclear transcription factor-kB(NF-kB) inflammation